RUN | Initial microstate | Final microstate | ΔΔG / kcal M-1 | ΔΔGexp / kcal M-1 | |ΔΔG-ΔΔGexp| / kcal M-1 | Work distribution | Convergence | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RUN56 | ADA-UCB-6c2cb422-1_1 |
|
JAN-GHE-5a013bed-1_1 |
|
−2.32 ± 0.08 | 1.8 ± 0.2 | 4.1 ± 0.2 |
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||||
RUN62 | ADA-UCB-6c2cb422-1_1 |
|
JAN-GHE-5a013bed-2_1 |
|
−2.2 ± 0.1 | 1.5 ± 0.2 | 3.7 ± 0.2 |
![]() |
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||||
RUN587 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-10_2 |
|
−2.1 ± 0.2 | 1.7 ± 0.2 | 3.6 ± 0.3 |
![]() |
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||||
RUN581 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-10_1 |
|
−1.3 ± 0.2 | 1.7 ± 0.2 | 3.6 ± 0.2 |
![]() |
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||||
RUN195 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-50fe53e8-1_1 |
|
−1.53 ± 0.08 | 2.0 ± 0.2 | 3.6 ± 0.2 |
![]() |
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||||
RUN649 | ADA-UCB-6c2cb422-1_1 |
|
RUB-POS-1325a9ea-20_1 |
|
−1.1 ± 0.1 | 2.7 ± 0.2 | 3.5 ± 0.2 |
![]() |
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||||
RUN651 | ADA-UCB-6c2cb422-1_1 |
|
RUB-POS-1325a9ea-20_2 |
|
−0.3 ± 0.1 | 2.7 ± 0.2 | 3.5 ± 0.2 |
![]() |
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||||
RUN590 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-17_1 |
|
−1.4 ± 0.2 | 2.0 ± 0.2 | 3.3 ± 0.3 |
![]() |
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||||
RUN586 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-17_2 |
|
−1.3 ± 0.2 | 2.0 ± 0.2 | 3.3 ± 0.3 |
![]() |
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||||
RUN718 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-5_1 |
|
−2.0 ± 0.2 | 1.2 ± 0.2 | 3.0 ± 0.2 |
![]() |
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||||
RUN678 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-5_2 |
|
−1.5 ± 0.1 | 1.2 ± 0.2 | 3.0 ± 0.2 |
![]() |
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||||
RUN585 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-6_4 |
|
−2.1 ± 0.1 | 1.4 ± 0.2 | 2.9 ± 0.2 |
![]() |
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||||
RUN584 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-6_1 |
|
−1.6 ± 0.2 | 1.4 ± 0.2 | 2.9 ± 0.2 |
![]() |
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||||
RUN578 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-6_3 |
|
−0.9 ± 0.2 | 1.4 ± 0.2 | 2.9 ± 0.2 |
![]() |
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||||
RUN571 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-6_2 |
|
−0.7 ± 0.2 | 1.4 ± 0.2 | 2.9 ± 0.2 |
![]() |
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||||
RUN632 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-24_1 |
|
−0.22 ± 0.08 | 2.7 ± 0.2 | 2.9 ± 0.2 |
![]() |
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||||
RUN671 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-1_1 |
|
−1.5 ± 0.2 | 1.4 ± 0.2 | 2.9 ± 0.3 |
![]() |
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||||
RUN257 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-bb423b95-1_1 |
|
−1.31 ± 0.08 | 1.4 ± 0.2 | 2.7 ± 0.2 |
![]() |
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||||
RUN576 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-8_1 |
|
−0.9 ± 0.2 | 2.0 ± 0.2 | 2.5 ± 0.2 |
![]() |
![]() |
||||
RUN569 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-8_2 |
|
0.6 ± 0.2 | 2.0 ± 0.2 | 2.5 ± 0.3 |
![]() |
![]() |
||||
RUN45 | ADA-UCB-6c2cb422-1_1 |
|
JAN-GHE-5a013bed-3_1 |
|
−0.9 ± 0.1 | 1.5 ± 0.2 | 2.4 ± 0.2 |
![]() |
![]() |
||||
RUN208 | ADA-UCB-6c2cb422-1_1 |
|
PET-UNK-8df914d1-2_1 |
|
3.8 ± 0.1 | 1.4 ± 0.2 | 2.4 ± 0.2 |
![]() |
![]() |
||||
RUN24 | ADA-UCB-6c2cb422-1_1 |
|
JAN-GHE-83b26c96-8_1 |
|
−0.63 ± 0.10 | 1.9 ± 0.2 | 2.2 ± 0.2 |
![]() |
![]() |
||||
RUN26 | ADA-UCB-6c2cb422-1_1 |
|
JAN-GHE-83b26c96-8_2 |
|
0.3 ± 0.1 | 1.9 ± 0.2 | 2.2 ± 0.2 |
![]() |
![]() |
||||
RUN567 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-16_1 |
|
−1.1 ± 0.2 | 1.5 ± 0.2 | 2.2 ± 0.3 |
![]() |
![]() |
||||
RUN573 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-16_2 |
|
0.5 ± 0.2 | 1.5 ± 0.2 | 2.2 ± 0.2 |
![]() |
![]() |
||||
RUN276 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-1e5f28a7-1_1 |
|
−0.4 ± 0.1 | 2.1 ± 0.2 | 2.0 ± 0.2 |
![]() |
![]() |
||||
RUN278 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-1e5f28a7-1_2 |
|
2.18 ± 0.10 | 2.1 ± 0.2 | 2.0 ± 0.2 |
![]() |
![]() |
||||
RUN591 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-12_1 |
|
−1.1 ± 0.2 | 0.9 ± 0.2 | 1.9 ± 0.2 |
![]() |
![]() |
||||
RUN597 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-4_4 |
|
2.3 ± 0.1 | 1.1 ± 0.2 | 1.9 ± 0.2 |
![]() |
![]() |
||||
RUN592 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-4_3 |
|
3.3 ± 0.1 | 1.1 ± 0.2 | 1.9 ± 0.2 |
![]() |
![]() |
||||
RUN598 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-4_1 |
|
4.6 ± 0.2 | 1.1 ± 0.2 | 1.9 ± 0.2 |
![]() |
![]() |
||||
RUN589 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-4_2 |
|
4.7 ± 0.2 | 1.1 ± 0.2 | 1.9 ± 0.2 |
![]() |
![]() |
||||
RUN287 | ADA-UCB-6c2cb422-1_1 |
|
ALP-POS-8b8a49e1-6_1 |
|
0.3 ± 0.1 | 2.6 ± 0.2 | 1.8 ± 0.2 |
![]() |
![]() |
||||
RUN289 | ADA-UCB-6c2cb422-1_1 |
|
ALP-POS-8b8a49e1-6_2 |
|
2.1 ± 0.1 | 2.6 ± 0.2 | 1.8 ± 0.2 |
![]() |
![]() |
||||
RUN630 | ADA-UCB-6c2cb422-1_1 |
|
RUB-POS-1325a9ea-13_1 |
|
0.25 ± 0.08 | 2.0 ± 0.2 | 1.8 ± 0.2 |
![]() |
![]() |
||||
RUN260 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-bb423b95-7_1 |
|
0.5 ± 0.1 | 2.3 ± 0.2 | 1.8 ± 0.2 |
![]() |
![]() |
||||
RUN647 | ADA-UCB-6c2cb422-1_1 |
|
RUB-POS-1325a9ea-14_1 |
|
−1.28 ± 0.09 | 0.4 ± 0.2 | 1.7 ± 0.2 |
![]() |
![]() |
||||
RUN221 | ADA-UCB-6c2cb422-1_1 |
|
PET-UNK-8df914d1-4_1 |
|
1.24 ± 0.09 | 2.9 ± 0.2 | 1.7 ± 0.2 |
![]() |
![]() |
||||
RUN604 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-3_1 |
|
2.3 ± 0.1 | 0.7 ± 0.2 | 1.6 ± 0.2 |
![]() |
![]() |
||||
RUN629 | ADA-UCB-6c2cb422-1_1 |
|
RUB-POS-1325a9ea-4_1 |
|
1.39 ± 0.08 | −0.2 ± 0.2 | 1.6 ± 0.2 |
![]() |
![]() |
||||
RUN61 | ADA-UCB-6c2cb422-1_1 |
|
EDG-MED-0da5ad92-2_1 |
|
1.02 ± 0.08 | 2.6 ± 0.2 | 1.5 ± 0.2 |
![]() |
![]() |
||||
RUN39 | ADA-UCB-6c2cb422-1_1 |
|
JAN-GHE-83b26c96-22_1 |
|
1.4 ± 0.1 | 2.9 ± 0.2 | 1.5 ± 0.2 |
![]() |
![]() |
||||
RUN556 | ADA-UCB-6c2cb422-1_1 |
|
RAL-THA-2d450e86-19_1 |
|
0.55 ± 0.04 | 2.1 ± 0.2 | 1.5 ± 0.2 |
![]() |
![]() |
||||
RUN190 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-00c1612e-1_1 |
|
1.63 ± 0.09 | 0.1 ± 0.2 | 1.5 ± 0.2 |
![]() |
![]() |
||||
RUN693 | ADA-UCB-6c2cb422-1_1 |
|
PET-UNK-b1ef24dc-1_1 |
|
0.62 ± 0.07 | 2.1 ± 0.2 | 1.5 ± 0.2 |
![]() |
![]() |
||||
RUN305 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-c8e7a002-4_1 |
|
1.45 ± 0.09 | 2.8 ± 0.2 | 1.3 ± 0.2 |
![]() |
![]() |
||||
RUN726 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-d8472c4f-2_2 |
|
1.4 ± 0.3 | 0.5 ± 0.2 | 1.3 ± 0.3 |
![]() |
![]() |
||||
RUN727 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-d8472c4f-2_1 |
|
9.1 ± 0.3 | 0.5 ± 0.2 | 1.3 ± 0.3 |
![]() |
![]() |
||||
RUN617 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-14_1 |
|
1.78 ± 0.08 | 0.6 ± 0.2 | 1.2 ± 0.2 |
![]() |
![]() |
||||
RUN588 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-18_1 |
|
−0.8 ± 0.2 | 0.7 ± 0.2 | 1.2 ± 0.2 |
![]() |
![]() |
||||
RUN577 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-18_2 |
|
0.3 ± 0.2 | 0.7 ± 0.2 | 1.2 ± 0.3 |
![]() |
![]() |
||||
RUN602 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-4_1 |
|
2.55 ± 0.10 | 1.5 ± 0.2 | 1.2 ± 0.2 |
![]() |
![]() |
||||
RUN606 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-4_2 |
|
2.84 ± 0.09 | 1.5 ± 0.2 | 1.2 ± 0.2 |
![]() |
![]() |
||||
RUN6 | ADA-UCB-6c2cb422-1_1 |
|
TRY-UNI-714a760b-18_2 |
|
0.60 ± 0.09 | 2.1 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN2 | ADA-UCB-6c2cb422-1_1 |
|
TRY-UNI-714a760b-18_1 |
|
2.74 ± 0.09 | 2.1 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN1 | ADA-UCB-6c2cb422-1_1 |
|
TRY-UNI-714a760b-6_1 |
|
0.98 ± 0.09 | 2.1 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN270 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-f7918075-8_1 |
|
0.63 ± 0.09 | 1.7 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN271 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-f7918075-5_1 |
|
−0.03 ± 0.08 | 1.1 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN256 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-bb423b95-2_1 |
|
0.27 ± 0.04 | 1.4 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN614 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-20_1 |
|
1.3 ± 0.1 | 2.4 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN559 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-fce787c2-1_1 |
|
2.4 ± 0.1 | 1.3 ± 0.2 | 1.1 ± 0.2 |
![]() |
![]() |
||||
RUN628 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-2_1 |
|
1.4 ± 0.3 | 0.8 ± 0.2 | 1.0 ± 0.3 |
![]() |
![]() |
||||
RUN633 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-cf4b0d25-2_2 |
|
3.8 ± 0.3 | 0.8 ± 0.2 | 1.0 ± 0.4 |
![]() |
![]() |
||||
RUN5 | ADA-UCB-6c2cb422-1_1 |
|
TRY-UNI-714a760b-3_1 |
|
0.06 ± 0.08 | 1.0 ± 0.2 | 1.0 ± 0.2 |
![]() |
![]() |
||||
RUN637 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-22_1 |
|
0.66 ± 0.07 | −0.3 ± 0.2 | 1.0 ± 0.2 |
![]() |
![]() |
||||
RUN565 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-1_2 |
|
0.4 ± 0.2 | 1.6 ± 0.2 | 0.9 ± 0.2 |
![]() |
![]() |
||||
RUN562 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-ee07cf00-1_1 |
|
2.8 ± 0.2 | 1.6 ± 0.2 | 0.9 ± 0.2 |
![]() |
![]() |
||||
RUN149 | ADA-UCB-6c2cb422-1_1 |
|
SAM-UNK-2684b532-12_1 |
|
1.07 ± 0.09 | 1.9 ± 0.2 | 0.9 ± 0.2 |
![]() |
![]() |
||||
RUN259 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-bb423b95-5_1 |
|
1.17 ± 0.10 | 2.0 ± 0.2 | 0.8 ± 0.2 |
![]() |
![]() |
||||
RUN49 | ADA-UCB-6c2cb422-1_1 |
|
JAN-GHE-5a013bed-11_1 |
|
1.7 ± 0.1 | 2.5 ± 0.2 | 0.8 ± 0.2 |
![]() |
![]() |
||||
RUN596 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-a13804f0-1_4 |
|
−0.3 ± 0.1 | 1.1 ± 0.2 | 0.7 ± 0.2 |
![]() |
![]() |
||||
RUN599 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-a13804f0-1_3 |
|
0.9 ± 0.1 | 1.1 ± 0.2 | 0.7 ± 0.2 |
![]() |
![]() |
||||
RUN593 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-a13804f0-1_2 |
|
2.7 ± 0.2 | 1.1 ± 0.2 | 0.7 ± 0.2 |
![]() |
![]() |
||||
RUN595 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-a13804f0-1_1 |
|
3.7 ± 0.2 | 1.1 ± 0.2 | 0.7 ± 0.2 |
![]() |
![]() |
||||
RUN210 | ADA-UCB-6c2cb422-1_1 |
|
MIC-UNK-08cd9c58-1_1 |
|
2.08 ± 0.08 | 2.7 ± 0.2 | 0.6 ± 0.2 |
![]() |
![]() |
||||
RUN344 | ADA-UCB-6c2cb422-1_1 |
|
MIC-UNK-50cce87d-1_1 |
|
−0.25 ± 0.07 | 0.3 ± 0.2 | 0.6 ± 0.2 |
![]() |
![]() |
||||
RUN612 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-11_1 |
|
0.97 ± 0.08 | 0.4 ± 0.2 | 0.6 ± 0.2 |
![]() |
![]() |
||||
RUN314 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-199e2e7c-1_1 |
|
1.72 ± 0.07 | 1.2 ± 0.2 | 0.6 ± 0.2 |
![]() |
![]() |
||||
RUN275 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-14ad9fe9-1_1 |
|
0.83 ± 0.08 | 1.4 ± 0.2 | 0.5 ± 0.2 |
![]() |
![]() |
||||
RUN211 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-0bc33984-1_1 |
|
2.56 ± 0.10 | 2.4 ± 0.2 | 0.4 ± 0.2 |
![]() |
![]() |
||||
RUN206 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-0bc33984-1_3 |
|
2.8 ± 0.1 | 2.4 ± 0.2 | 0.4 ± 0.2 |
![]() |
![]() |
||||
RUN215 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-0bc33984-1_2 |
|
3.0 ± 0.1 | 2.4 ± 0.2 | 0.4 ± 0.2 |
![]() |
![]() |
||||
RUN218 | ADA-UCB-6c2cb422-1_1 |
|
MAT-POS-0bc33984-1_4 |
|
3.1 ± 0.1 | 2.4 ± 0.2 | 0.4 ± 0.2 |
![]() |
![]() |
||||
RUN601 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-3_1 |
|
1.7 ± 0.1 | 2.0 ± 0.2 | 0.3 ± 0.2 |
![]() |
![]() |
||||
RUN191 | ADA-UCB-6c2cb422-1_1 |
|
EDJ-MED-976da9a6-1_1 |
|
1.92 ± 0.07 | 1.7 ± 0.2 | 0.3 ± 0.2 |
![]() |
![]() |
||||
RUN625 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-21_1 |
|
1.21 ± 0.10 | 1.5 ± 0.2 | 0.3 ± 0.2 |
![]() |
![]() |
||||
RUN339 | ADA-UCB-6c2cb422-1_1 |
|
MIC-UNK-50cce87d-3_1 |
|
−0.25 ± 0.06 | −0.5 ± 0.2 | 0.2 ± 0.2 |
![]() |
![]() |
||||
RUN621 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-13_1 |
|
0.18 ± 0.03 | 0.1 ± 0.2 | 0.1 ± 0.2 |
![]() |
![]() |
||||
RUN184 | ADA-UCB-6c2cb422-1_1 |
|
ALP-POS-0c2c77e1-1_1 |
|
2.3 ± 0.1 | 2.4 ± 0.2 | 0.1 ± 0.2 |
![]() |
![]() |
||||
RUN611 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-9_1 |
|
1.59 ± 0.08 | 1.6 ± 0.2 | 0.0 ± 0.2 |
![]() |
![]() |
||||
RUN154 | ADA-UCB-6c2cb422-1_1 |
|
ADA-UCB-6c2cb422-1_1 |
|
−0.03 ± 0.02 | 0.0 ± 0.2 | 0.0 ± 0.2 |
![]() |
![]() |
||||
RUN607 | ADA-UCB-6c2cb422-1_1 |
|
JIN-POS-6dc588a4-6_1 |
|
2.1 ± 0.1 | 2.1 ± 0.2 | 0.0 ± 0.2 |
![]() |
![]() |
||||
RUN34 | ADA-UCB-6c2cb422-1_1 |
|
ALP-POS-95b75b4d-5_1 |
|
1.36 ± 0.10 | 1.4 ± 0.2 | 0.0 ± 0.2 |
![]() |
![]() |