Compounds

Showing 201 through 300 of 408
Rank Compound SMILES ΔG / kcal M-1 pIC50
201 EDJ-MED-40e596c8-3 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CCNC(=O)C6CC6 −8.4 ± 0.5 6.1 ± 0.4
202 EDJ-MED-6b23330e-3 molecule CC(C)(CNC(=O)CN1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl)C#N −8.4 ± 0.4 6.1 ± 0.3
203 EDJ-MED-33064c06-10 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CC(=O)NCC6(CC6)CO −8.4 ± 0.3 6.1 ± 0.2
204 MAT-POS-853c0ffa-11 molecule CC(C)(c1ccc2cncc(c2c1)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N)O −8.4 ± 0.8 6.1 ± 0.6
205 MIK-ENA-794411b8-1 molecule CNC(=O)CN1C[C@@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.4 ± 0.3 6.1 ± 0.2
206 LUO-POS-9931618f-2 molecule CNC(=O)CN1C[C@@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.4 ± 0.3 6.1 ± 0.2
207 MAT-POS-e75f6e44-6 molecule CNC1(CC1)CNC(=O)CN2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −8.4 ± 0.6 6.1 ± 0.5
208 MAT-POS-e75f6e44-18 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(=O)NCC6CC(C6)F −8.4 ± 0.3 6.1 ± 0.3
209 ALP-POS-ecbed2ba-16 molecule CN(CCC#N)S(=O)(=O)N1Cc2ccc(cc2C3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −8.4 ± 1.0 6.1 ± 0.7
210 ALP-POS-c3a90b22-1 molecule CNC(=O)C1(CCC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −8.3 ± 0.7 6.1 ± 0.5
211 MIK-ENA-37e0b697-1 molecule CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.3 ± 0.3 6.1 ± 0.2
212 PET-UNK-94036022-7 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)C(=O)C(=C)N(C3=O)c4cncc5c4cccc5)Cl −8.3 ± 0.3 6.1 ± 0.2
213 ALP-POS-c3a90b22-5 molecule CNC(=O)CCN1CC2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.3 ± 0.4 6.1 ± 0.3
214 JOH-MSK-51c67e7d-1 molecule CN1Cc2ccc(cc2[C@@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl −8.3 ± 0.3 6.1 ± 0.2
215 VLA-UNK-61877630-10 molecule c1ccc2c(c1)cncc2N3CC[C@]4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C(F)(F)F −8.3 ± 0.9 6.0 ± 0.7
216 EDJ-MED-cc48ee33-3 molecule Cn1c(ccn1)C(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −8.3 ± 0.2 6.0 ± 0.2
217 VLA-UNK-e334495f-4 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)c5cc(ccc5CN(C4C(F)F)S(=O)(=O)CC6(CC6)C#N)Cl −8.3 ± 0.5 6.0 ± 0.4
218 EDJ-MED-ee81482e-5 molecule c1cc2cncc(c2cc1CN3CC4(C3)COC4)N5CCC6(C5=O)CN(Cc7c6cc(cc7)Cl)S(=O)(=O)CC8(CC8)C#N −8.3 ± 0.8 6.0 ± 0.6
219 PET-UNK-626a1084-2 molecule C#CCN1C[C@]2(CC(=O)N(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.3 ± 0.4 6.0 ± 0.3
220 MIK-ENA-e143773d-1 molecule CC[C@H]1CN(C(=O)[C@@]12CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 −8.3 ± 0.8 6.0 ± 0.6
221 LUO-POS-e1dab717-2 molecule CNC(=O)C1(CC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −8.2 ± 0.3 6.0 ± 0.2
222 MAT-POS-853c0ffa-1 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3c(ccc4)Cl)c5cc(ccc5C1=O)Cl −8.2 ± 0.1 5.99 ± 0.09
223 PET-UNK-37c7074c-2 molecule c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)Cc6ccon6 −8.2 ± 0.2 6.0 ± 0.1
224 EDJ-MED-9f4ac58c-2 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −8.2 ± 0.6 6.0 ± 0.4
225 EDJ-MED-94fddcec-5 molecule CS(=O)(=O)c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −8.2 ± 0.5 6.0 ± 0.3
226 PET-UNK-c6bcc80b-11 molecule CS(=O)(=O)Nc1cc2cncc(c2cc1F)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −8.2 ± 0.9 6.0 ± 0.6
227 EDJ-MED-33064c06-13 molecule CNC(=O)C1(COC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −8.2 ± 0.3 6.0 ± 0.2
228 VLA-UNK-61877630-3 molecule CNC(=O)CN1C([C@@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl)C(F)(F)F −8.2 ± 0.3 5.9 ± 0.2
229 PET-UNK-94036022-14 molecule CNC(=O)CN1Cc2ccc(cc2C3(C1)C(=O)C(=C)N(C3=O)c4cncc5c4cccc5)Cl −8.2 ± 0.3 5.9 ± 0.2
230 PET-UNK-37c7074c-1 molecule c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)Cc6ccno6 −8.1 ± 0.2 5.9 ± 0.1
231 MAT-POS-e75f6e44-20 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(=O)NCC6CS(=O)(=O)C6 −8.1 ± 0.5 5.9 ± 0.3
232 MAT-POS-50a80394-5 molecule CCC1CN(C(=O)C12CN(Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5 −8.1 ± 0.2 5.9 ± 0.1
233 MAT-POS-1d5ab790-3 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3c(ccc4)Cl)c5cc(ccc5C1=O)Cl −8.1 ± 0.1 5.91 ± 0.09
234 BEN-BAS-c2bc0d80-6 molecule c1ccc2c(c1)cncc2N3C(=O)CC4(C3=O)CCOc5c4cc(cc5)Cl −8.1 ± 0.1 5.90 ± 0.08
235 MAT-POS-50a80394-7 molecule CC1(CN(C(=O)C12CN(Cc3c2cc(cc3)Cl)CC(=O)NC)c4cncc5c4cccc5)C −8.1 ± 0.3 5.9 ± 0.3
236 MAT-POS-c7726e07-5 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)CCN(C3=O)c4cncc5c4cccc5)Cl −8.1 ± 0.2 5.9 ± 0.1
237 PET-UNK-626a1084-4 molecule C#CCN1CC2(CC(=O)N(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −8.1 ± 0.3 5.9 ± 0.3
238 EDJ-MED-40e596c8-2 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CS(=O)(=O)NCC6CC6 −8.1 ± 0.7 5.9 ± 0.5
239 MAT-POS-e75f6e44-17 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(=O)NCC6(CCC6)O −8.0 ± 0.3 5.9 ± 0.2
240 MAT-POS-566864e2-3 molecule CNC(=O)C1(CC1)N2Cc3ccc(cc3[C@]4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −8.0 ± 0.2 5.8 ± 0.2
241 ALP-POS-4483ae88-1 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CNS(=O)(=O)c5c4cc(cc5)Cl −8.0 ± 0.4 5.8 ± 0.3
242 ALP-POS-c3a90b22-8 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CS(=O)(=O)CC6(CC6)C#N −8.0 ± 0.4 5.8 ± 0.3
243 MAT-POS-576f7758-2 molecule CNC(=O)C1(CC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −8.0 ± 0.3 5.8 ± 0.3
244 MAT-POS-be048f2c-7 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)C(=O)c6ccnn6C7CC7 −8.0 ± 0.3 5.8 ± 0.2
245 EDJ-MED-94fddcec-4 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −7.9 ± 0.4 5.8 ± 0.3
246 MAT-POS-ddfe83c6-1 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cc(cc4)OC)c5cc(ccc5C1=O)Cl −7.9 ± 0.3 5.8 ± 0.2
247 PET-UNK-aa57768f-3 molecule C#CCN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −7.9 ± 0.3 5.8 ± 0.2
248 EDJ-MED-98c0a822-1 molecule CNC(=O)C1(CCC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6S2(=O)=O)Cl −7.9 ± 0.7 5.7 ± 0.5
249 PET-UNK-626a1084-3 molecule c1ccc2c(c1)cncc2N3C(=O)CC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CC#N −7.9 ± 0.2 5.7 ± 0.2
250 VLA-UNK-61877630-6 molecule CNC(=O)CN1C([C@@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl)C(F)F −7.8 ± 0.3 5.7 ± 0.2
251 MAT-POS-576f7758-1 molecule CNC(=O)C1(CC1)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −7.8 ± 0.3 5.7 ± 0.2
252 JOH-MSK-1f2dff76-2 molecule CNC(=O)CN1Cc2ccc(cc2[C@]3(C1)CC(=O)N(C3=O)c4cncc5c4cccc5)Cl −7.8 ± 0.2 5.7 ± 0.2
253 PET-UNK-14142a25-10 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −7.8 ± 0.3 5.7 ± 0.2
254 EDJ-MED-ede5c6cb-1 molecule CS(=O)(=O)Nc1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl −7.8 ± 0.4 5.7 ± 0.3
255 EDJ-MED-33064c06-4 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CC(=O)NCC6CS(=O)(=O)C6 −7.8 ± 0.4 5.7 ± 0.3
256 ALP-POS-ecbed2ba-15 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CCCC6)C#N −7.8 ± 1.0 5.7 ± 0.7
257 MIK-ENA-5d9157e9-1 molecule c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.7 ± 0.6 5.6 ± 0.5
258 PET-UNK-626a1084-1 molecule c1ccc2c(c1)cncc2N3C(=O)C[C@@]4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CC#N −7.7 ± 0.3 5.6 ± 0.2
259 VLA-UNK-5d8210f0-4 molecule CNC(=O)CN1Cc2ccc(cc2C3(C1C(F)(F)F)CCN(C3=O)c4cncc5c4cccc5)Cl −7.7 ± 0.4 5.6 ± 0.3
260 JOH-MSK-4bb3d434-2 molecule COC(=O)CN1CC2(CC(=O)N(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −7.7 ± 0.3 5.6 ± 0.2
261 LUO-POS-e1dab717-5 molecule CNC(=O)C1(CC1)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cc(cc6)OC)Cl −7.7 ± 0.3 5.6 ± 0.2
262 EDJ-MED-59d5ca70-1 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)C6(CC6)C(=O)NCC7CC7 −7.7 ± 0.3 5.6 ± 0.2
263 JOH-MSK-4bb3d434-1 molecule COC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −7.6 ± 0.3 5.5 ± 0.2
264 EDJ-MED-40e596c8-4 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CCNC(=O)C6CC6 −7.6 ± 0.3 5.5 ± 0.2
265 LUO-POS-e1dab717-11 molecule CCNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5S1(=O)=O)Cl −7.6 ± 0.5 5.5 ± 0.3
266 EDJ-MED-33064c06-5 molecule CN(C)C1(CC1)CNC(=O)CN2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −7.6 ± 0.4 5.5 ± 0.3
267 MAT-POS-853c0ffa-12 molecule CC(C)(c1ccc2cncc(c2c1)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)OC)O −7.5 ± 0.8 5.5 ± 0.6
268 EDJ-MED-33064c06-11 molecule CNC(=O)C1(CCOCC1)N2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −7.5 ± 0.5 5.5 ± 0.4
269 VLA-UNK-61877630-4 molecule CNC(=O)CN1C[C@@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(cc(c5C1=O)F)Cl −7.5 ± 0.3 5.5 ± 0.2
270 MAT-POS-38eb6498-4 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cc(cc4)OCCN(C)C)c5cc(ccc5C1=O)Cl −7.5 ± 0.5 5.4 ± 0.4
271 ALP-POS-c3a90b22-4 molecule CNC(=O)C1(COC1)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −7.4 ± 0.3 5.4 ± 0.2
272 MAT-POS-be048f2c-6 molecule CC(C)n1c(ccn1)C(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −7.4 ± 0.4 5.4 ± 0.3
273 VLA-UNK-61877630-8 molecule c1ccc2c(c1)cncc2N3CC[C@]4(C3=O)CN(Cc5c4cc(c(c5)F)Cl)S(=O)(=O)CC6(CC6)C#N −7.4 ± 0.8 5.4 ± 0.6
274 VLA-UNK-e334495f-1 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5F)Cl)S(=O)(=O)CC6(CC6)C#N −7.4 ± 0.8 5.4 ± 0.6
275 EDJ-MED-b6c6ee2b-3 molecule COc1ccc2cncc(c2c1)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.4 ± 0.9 5.4 ± 0.6
276 VLA-UNK-3bd6fc51-1 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)CC(F)(F)Cl −7.4 ± 0.2 5.4 ± 0.1
277 EDJ-MED-8bb691af-8 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −7.4 ± 0.3 5.4 ± 0.2
278 ALP-POS-ecbed2ba-8 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CCC6)C#N −7.4 ± 0.9 5.4 ± 0.6
279 ALP-POS-ecbed2ba-1 molecule CC1(CS(=O)(=O)C1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cccc6)Cl −7.3 ± 0.8 5.4 ± 0.6
280 MIC-UNK-c85ea37c-1 molecule c1ccc2c(c1)cncc2N3CC(C4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N)CC7CCCCC7 −7.3 ± 0.9 5.3 ± 0.6
281 MAT-POS-853c0ffa-7 molecule COC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5c(ccc6)Cl)Cl −7.3 ± 0.6 5.3 ± 0.5
282 EDJ-MED-94fddcec-6 molecule CN(c1ccc2c(c1)cncc2N3CCC4(C3=O)CCS(=O)(=O)c5c4cc(cc5)Cl)S(=O)(=O)C −7.3 ± 0.5 5.3 ± 0.4
283 VLA-UNK-61877630-7 molecule c1ccc2c(c1)cncc2N3CC[C@]4(C3=O)CN(Cc5c4cc(cc5F)Cl)S(=O)(=O)CC6(CC6)C#N −7.3 ± 0.9 5.3 ± 0.6
284 EDJ-MED-4138fde9-6 molecule CNC(=O)C1(CC1)N2CC3(CCN(C3=O)c4cncc5c4cc(cc5)OCCNCC(F)(F)F)c6cc(ccc6C2=O)Cl −7.3 ± 0.6 5.3 ± 0.5
285 MAT-POS-853c0ffa-13 molecule c1cc2cncc(c2cc1F)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.3 ± 0.9 5.3 ± 0.6
286 EDJ-MED-4138fde9-4 molecule CNC(=O)C1(CC1)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5cc(cc6)OCCNCC(F)(F)F)Cl −7.3 ± 0.4 5.3 ± 0.3
287 VLA-UNK-8e615992-2 molecule CNC(=O)CN1CC2(CCN(C2=O)c3cncc4c3cccc4)c5cc(c(cc5C1=O)F)Cl −7.2 ± 0.4 5.3 ± 0.3
288 EDJ-MED-33064c06-6 molecule CN1CC(C1)CNC(=O)CN2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −7.2 ± 0.4 5.3 ± 0.3
289 12_-111-3e02a1cd-2 molecule COC(=O)CN1C[C@]2(CC(=O)N(C2=O)c3cncc4c3cccc4)c5cc(ccc5C1=O)Cl −7.2 ± 0.3 5.3 ± 0.2
290 PET-UNK-94036022-11 molecule C#CC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CC(=O)N(C4=O)c5cncc6c5cccc6)Cl −7.2 ± 0.8 5.2 ± 0.6
291 MAT-POS-853c0ffa-17 molecule CC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3C4(C2)CCN(C4=O)c5cncc6c5c(ccc6)Cl)Cl −7.1 ± 0.9 5.2 ± 0.6
292 MAT-POS-853c0ffa-5 molecule c1cc2cncc(c2c(c1)Cl)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.1 ± 0.1 5.15 ± 0.10
293 EDJ-MED-33064c06-3 molecule CNC1(CC1)CNC(=O)CN2CC3(CCN(C3=O)c4cncc5c4cccc5)c6cc(ccc6C2=O)Cl −7.0 ± 0.5 5.1 ± 0.4
294 MAT-POS-1d5ab790-1 molecule c1cc2cncc(c2c(c1)Cl)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −7.0 ± 0.1 5.09 ± 0.10
295 MIK-ENA-be04d1d4-1 molecule CC[C@H]1CN(C(=O)[C@]12CN(Cc3c2cc(cc3)Cl)S(=O)(=O)CC4(CC4)C#N)c5cncc6c5cccc6 −7.0 ± 0.8 5.1 ± 0.6
296 EDJ-MED-b6c6ee2b-4 molecule c1cc2cncc(c2cc1Cl)N3CCC4(C3=O)CN(Cc5c4cc(cc5)Cl)S(=O)(=O)CC6(CC6)C#N −6.9 ± 0.7 5.0 ± 0.5
297 PET-UNK-94036022-4 molecule C#CC1(CC1)CS(=O)(=O)N2Cc3ccc(cc3[C@]4(C2)CC(=O)N(C4=O)c5cncc6c5cccc6)Cl −6.9 ± 0.6 5.0 ± 0.4
298 EDJ-MED-40e596c8-5 molecule c1ccc2c(c1)cncc2N3CCC4(C3=O)CN(C(=O)c5c4cc(cc5)Cl)CS(=O)(=O)NCC6CC6 −6.8 ± 0.4 5.0 ± 0.3
299 EDJ-MED-dfa1d800-1 molecule CNC(=O)C1(CC1)N2CC3(CCN(C3=O)c4cncc5c4cc(cc5)OCCN6CCCC6)c7cc(ccc7C2=O)Cl −6.8 ± 0.4 5.0 ± 0.3
300 VLA-UNK-f2612802-3 molecule CNC(=O)CN1C[C@]2(CCN(C2=O)c3cncc4c3cccc4)c5cc(cc(c5S1(=O)=O)F)Cl −6.8 ± 0.5 4.9 ± 0.3
Last updated 2022-02-18T19:21:08.310654+00:00
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