RUN | Initial microstate | Final microstate | ΔΔG / kcal M-1 | ΔΔGexp / kcal M-1 | |ΔΔG-ΔΔGexp| / kcal M-1 | Work distribution | Convergence | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RUN52 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-2_1 | −2.9 ± 0.1 | 1.5 ± 0.2 | 4.3 ± 0.2 | ||||||||
RUN278 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bfb445d4-2_1 | −2.3 ± 0.2 | 1.2 ± 0.2 | 3.5 ± 0.3 | ||||||||
RUN257 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-7_1 | −0.9 ± 0.3 | 2.3 ± 0.2 | 3.2 ± 0.4 | ||||||||
RUN218 | ADA-UCB-6c2cb422-1_1 | MIC-UNK-08cd9c58-1_1 | 0.11 ± 0.06 | 2.7 ± 0.2 | 2.6 ± 0.2 | ||||||||
RUN212 | ADA-UCB-6c2cb422-1_1 | PET-UNK-8df914d1-2_1 | 3.8 ± 0.3 | 1.4 ± 0.2 | 2.4 ± 0.3 | ||||||||
RUN50 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-1_1 | −0.5 ± 0.2 | 1.8 ± 0.2 | 2.3 ± 0.2 | ||||||||
RUN300 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-c8e7a002-4_1 | 0.8 ± 0.3 | 2.8 ± 0.2 | 1.9 ± 0.3 | ||||||||
RUN272 | ADA-UCB-6c2cb422-1_1 | MAT-POS-1e5f28a7-1_1 | −0.2 ± 0.2 | 2.1 ± 0.2 | 1.9 ± 0.3 | ||||||||
RUN273 | ADA-UCB-6c2cb422-1_1 | MAT-POS-1e5f28a7-1_2 | 7.2 ± 0.4 | 2.1 ± 0.2 | 1.9 ± 0.4 | ||||||||
RUN208 | ADA-UCB-6c2cb422-1_1 | MAT-POS-0bc33984-1_2 | 4.0 ± 0.2 | 2.4 ± 0.2 | 1.9 ± 0.3 | ||||||||
RUN211 | ADA-UCB-6c2cb422-1_1 | MAT-POS-0bc33984-1_3 | 4.2 ± 0.2 | 2.4 ± 0.2 | 1.9 ± 0.3 | ||||||||
RUN207 | ADA-UCB-6c2cb422-1_1 | MAT-POS-0bc33984-1_1 | 4.4 ± 0.2 | 2.4 ± 0.2 | 1.9 ± 0.3 | ||||||||
RUN210 | ADA-UCB-6c2cb422-1_1 | MAT-POS-0bc33984-1_4 | 5.7 ± 0.2 | 2.4 ± 0.2 | 1.9 ± 0.3 | ||||||||
RUN288 | ADA-UCB-6c2cb422-1_1 | ALP-POS-8b8a49e1-6_1 | 0.4 ± 0.2 | 2.6 ± 0.2 | 1.7 ± 0.3 | ||||||||
RUN292 | ADA-UCB-6c2cb422-1_1 | ALP-POS-8b8a49e1-6_2 | 3.5 ± 0.2 | 2.6 ± 0.2 | 1.7 ± 0.3 | ||||||||
RUN258 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-5_1 | 3.7 ± 0.1 | 2.0 ± 0.2 | 1.7 ± 0.2 | ||||||||
RUN255 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-1_1 | 0.04 ± 0.04 | 1.4 ± 0.2 | 1.4 ± 0.2 | ||||||||
RUN31 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-83b26c96-22_1 | 4.3 ± 0.4 | 2.9 ± 0.2 | 1.4 ± 0.4 | ||||||||
RUN183 | ADA-UCB-6c2cb422-1_1 | ALP-POS-0c2c77e1-1_1 | 3.8 ± 0.3 | 2.4 ± 0.2 | 1.4 ± 0.3 | ||||||||
RUN4 | ADA-UCB-6c2cb422-1_1 | TRY-UNI-714a760b-3_1 | 2.3 ± 0.3 | 1.0 ± 0.2 | 1.2 ± 0.3 | ||||||||
RUN269 | ADA-UCB-6c2cb422-1_1 | MAT-POS-f7918075-5_1 | −0.13 ± 0.03 | 1.1 ± 0.2 | 1.2 ± 0.2 | ||||||||
RUN2 | ADA-UCB-6c2cb422-1_1 | TRY-UNI-714a760b-6_1 | 3.3 ± 0.3 | 2.1 ± 0.2 | 1.2 ± 0.3 | ||||||||
RUN277 | ADA-UCB-6c2cb422-1_1 | MAT-POS-14ad9fe9-1_1 | 0.3 ± 0.2 | 1.4 ± 0.2 | 1.1 ± 0.3 | ||||||||
RUN312 | ADA-UCB-6c2cb422-1_1 | MAT-POS-199e2e7c-1_1 | 2.0 ± 0.2 | 1.2 ± 0.2 | 0.8 ± 0.2 | ||||||||
RUN22 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-83b26c96-8_2 | 0.7 ± 0.3 | 1.9 ± 0.2 | 0.7 ± 0.4 | ||||||||
RUN23 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-83b26c96-8_1 | 8.2 ± 0.3 | 1.9 ± 0.2 | 0.7 ± 0.3 | ||||||||
RUN260 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-2_1 | 0.6 ± 0.1 | 1.4 ± 0.2 | 0.7 ± 0.2 | ||||||||
RUN40 | ADA-UCB-6c2cb422-1_1 | ALP-POS-95b75b4d-5_1 | 2.1 ± 0.2 | 1.4 ± 0.2 | 0.7 ± 0.2 | ||||||||
RUN184 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-50fe53e8-1_1 | 2.6 ± 0.2 | 2.0 ± 0.2 | 0.6 ± 0.3 | ||||||||
RUN149 | ADA-UCB-6c2cb422-1_1 | SAM-UNK-2684b532-12_1 | 1.4 ± 0.2 | 1.9 ± 0.2 | 0.5 ± 0.2 | ||||||||
RUN199 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-976da9a6-1_1 | 2.2 ± 0.3 | 1.7 ± 0.2 | 0.5 ± 0.3 | ||||||||
RUN5 | ADA-UCB-6c2cb422-1_1 | TRY-UNI-714a760b-18_2 | 2.2 ± 0.2 | 2.1 ± 0.2 | 0.5 ± 0.2 | ||||||||
RUN1 | ADA-UCB-6c2cb422-1_1 | TRY-UNI-714a760b-18_1 | 4.3 ± 0.3 | 2.1 ± 0.2 | 0.5 ± 0.3 | ||||||||
RUN67 | ADA-UCB-6c2cb422-1_1 | EDG-MED-0da5ad92-2_1 | 2.1 ± 0.2 | 2.6 ± 0.2 | 0.4 ± 0.3 | ||||||||
RUN57 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-3_1 | 1.8 ± 0.3 | 1.5 ± 0.2 | 0.4 ± 0.3 | ||||||||
RUN271 | ADA-UCB-6c2cb422-1_1 | MAT-POS-f7918075-8_1 | 2.1 ± 0.3 | 1.7 ± 0.2 | 0.4 ± 0.4 | ||||||||
RUN344 | ADA-UCB-6c2cb422-1_1 | MIC-UNK-50cce87d-1_1 | 0.03 ± 0.03 | 0.3 ± 0.2 | 0.3 ± 0.2 | ||||||||
RUN189 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-00c1612e-1_1 | 0.4 ± 0.2 | 0.1 ± 0.2 | 0.3 ± 0.3 | ||||||||
RUN340 | ADA-UCB-6c2cb422-1_1 | MIC-UNK-50cce87d-3_1 | −0.3 ± 0.2 | −0.5 ± 0.2 | 0.2 ± 0.2 | ||||||||
RUN46 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-11_1 | 2.3 ± 0.3 | 2.5 ± 0.2 | 0.2 ± 0.3 | ||||||||
RUN215 | ADA-UCB-6c2cb422-1_1 | PET-UNK-8df914d1-4_1 | 2.9 ± 0.7 | 2.9 ± 0.2 | 0.0 ± 0.7 | ||||||||
RUN152 | ADA-UCB-6c2cb422-1_1 | ADA-UCB-6c2cb422-1_1 | −0.01 ± 0.03 | 0.0 ± 0.2 | 0.0 ± 0.2 |