RUN | Initial microstate | Final microstate | ΔΔG / kcal M-1 | ΔΔGexp / kcal M-1 | |ΔΔG-ΔΔGexp| / kcal M-1 | Work distribution | Convergence | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RUN52 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-2_1 | −2.9 ± 0.1 | 1.5 ± 0.2 | 4.3 ± 0.2 | ||||||||
RUN711 | ADA-UCB-6c2cb422-1_1 | PET-UNK-b1ef24dc-1_1 | −1.6 ± 0.1 | 2.1 ± 0.2 | 3.6 ± 0.2 | ||||||||
RUN300 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-c8e7a002-4_1 | −0.3 ± 0.2 | 2.8 ± 0.2 | 3.1 ± 0.2 | ||||||||
RUN278 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bfb445d4-2_1 | −1.8 ± 0.1 | 1.2 ± 0.2 | 3.0 ± 0.2 | ||||||||
RUN212 | ADA-UCB-6c2cb422-1_1 | PET-UNK-8df914d1-2_1 | 4.0 ± 0.2 | 1.4 ± 0.2 | 2.6 ± 0.2 | ||||||||
RUN218 | ADA-UCB-6c2cb422-1_1 | MIC-UNK-08cd9c58-1_1 | 0.10 ± 0.04 | 2.7 ± 0.2 | 2.6 ± 0.2 | ||||||||
RUN50 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-1_1 | −0.6 ± 0.1 | 1.8 ± 0.2 | 2.4 ± 0.2 | ||||||||
RUN257 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-7_1 | 0.2 ± 0.2 | 2.3 ± 0.2 | 2.1 ± 0.3 | ||||||||
RUN643 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-24_1 | 0.8 ± 0.1 | 2.7 ± 0.2 | 1.9 ± 0.2 | ||||||||
RUN632 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-6_1 | 3.8 ± 0.2 | 2.1 ± 0.2 | 1.8 ± 0.2 | ||||||||
RUN557 | ADA-UCB-6c2cb422-1_1 | RAL-THA-2d450e86-19_1 | 0.39 ± 0.04 | 2.1 ± 0.2 | 1.7 ± 0.2 | ||||||||
RUN258 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-5_1 | 3.5 ± 0.1 | 2.0 ± 0.2 | 1.6 ± 0.2 | ||||||||
RUN255 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-1_1 | 0.00 ± 0.03 | 1.4 ± 0.2 | 1.4 ± 0.2 | ||||||||
RUN665 | ADA-UCB-6c2cb422-1_1 | RUB-POS-1325a9ea-13_1 | 0.8 ± 0.1 | 2.0 ± 0.2 | 1.3 ± 0.2 | ||||||||
RUN269 | ADA-UCB-6c2cb422-1_1 | MAT-POS-f7918075-5_1 | −0.17 ± 0.02 | 1.1 ± 0.2 | 1.2 ± 0.2 | ||||||||
RUN630 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-10_1 | 1.7 ± 0.1 | 2.8 ± 0.2 | 1.1 ± 0.2 | ||||||||
RUN645 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-20_1 | 1.3 ± 0.2 | 2.4 ± 0.2 | 1.1 ± 0.2 | ||||||||
RUN277 | ADA-UCB-6c2cb422-1_1 | MAT-POS-14ad9fe9-1_1 | 0.3 ± 0.1 | 1.4 ± 0.2 | 1.1 ± 0.2 | ||||||||
RUN654 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-22_1 | 0.72 ± 0.09 | −0.3 ± 0.2 | 1.0 ± 0.2 | ||||||||
RUN634 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-14_1 | 1.6 ± 0.1 | 0.6 ± 0.2 | 1.0 ± 0.2 | ||||||||
RUN67 | ADA-UCB-6c2cb422-1_1 | EDG-MED-0da5ad92-2_1 | 1.6 ± 0.1 | 2.6 ± 0.2 | 1.0 ± 0.2 | ||||||||
RUN184 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-50fe53e8-1_1 | 1.0 ± 0.1 | 2.0 ± 0.2 | 1.0 ± 0.2 | ||||||||
RUN639 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-11_1 | −0.53 ± 0.10 | 0.4 ± 0.2 | 0.9 ± 0.2 | ||||||||
RUN40 | ADA-UCB-6c2cb422-1_1 | ALP-POS-95b75b4d-5_1 | 2.2 ± 0.1 | 1.4 ± 0.2 | 0.8 ± 0.2 | ||||||||
RUN57 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-3_1 | 0.7 ± 0.2 | 1.5 ± 0.2 | 0.8 ± 0.2 | ||||||||
RUN651 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-21_1 | 0.71 ± 0.08 | 1.5 ± 0.2 | 0.8 ± 0.2 | ||||||||
RUN183 | ADA-UCB-6c2cb422-1_1 | ALP-POS-0c2c77e1-1_1 | 3.1 ± 0.1 | 2.4 ± 0.2 | 0.7 ± 0.2 | ||||||||
RUN260 | ADA-UCB-6c2cb422-1_1 | MAT-POS-bb423b95-2_1 | 0.68 ± 0.08 | 1.4 ± 0.2 | 0.7 ± 0.2 | ||||||||
RUN31 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-83b26c96-22_1 | 2.3 ± 0.1 | 2.9 ± 0.2 | 0.6 ± 0.2 | ||||||||
RUN560 | ADA-UCB-6c2cb422-1_1 | MAT-POS-fce787c2-1_1 | 1.9 ± 0.2 | 1.3 ± 0.2 | 0.6 ± 0.2 | ||||||||
RUN149 | ADA-UCB-6c2cb422-1_1 | SAM-UNK-2684b532-12_1 | 1.4 ± 0.1 | 1.9 ± 0.2 | 0.5 ± 0.2 | ||||||||
RUN271 | ADA-UCB-6c2cb422-1_1 | MAT-POS-f7918075-8_1 | 1.3 ± 0.1 | 1.7 ± 0.2 | 0.4 ± 0.2 | ||||||||
RUN661 | ADA-UCB-6c2cb422-1_1 | RUB-POS-1325a9ea-12_1 | 0.2 ± 0.1 | 0.6 ± 0.2 | 0.4 ± 0.2 | ||||||||
RUN340 | ADA-UCB-6c2cb422-1_1 | MIC-UNK-50cce87d-3_1 | −0.08 ± 0.10 | −0.5 ± 0.2 | 0.4 ± 0.2 | ||||||||
RUN312 | ADA-UCB-6c2cb422-1_1 | MAT-POS-199e2e7c-1_1 | 1.54 ± 0.09 | 1.2 ± 0.2 | 0.4 ± 0.2 | ||||||||
RUN344 | ADA-UCB-6c2cb422-1_1 | MIC-UNK-50cce87d-1_1 | 0.03 ± 0.02 | 0.3 ± 0.2 | 0.3 ± 0.2 | ||||||||
RUN653 | ADA-UCB-6c2cb422-1_1 | RUB-POS-1325a9ea-4_1 | 0.12 ± 0.09 | −0.2 ± 0.2 | 0.3 ± 0.2 | ||||||||
RUN673 | ADA-UCB-6c2cb422-1_1 | RUB-POS-1325a9ea-14_1 | 0.2 ± 0.1 | 0.4 ± 0.2 | 0.3 ± 0.2 | ||||||||
RUN4 | ADA-UCB-6c2cb422-1_1 | TRY-UNI-714a760b-3_1 | 1.3 ± 0.1 | 1.0 ± 0.2 | 0.3 ± 0.2 | ||||||||
RUN2 | ADA-UCB-6c2cb422-1_1 | TRY-UNI-714a760b-6_1 | 1.9 ± 0.1 | 2.1 ± 0.2 | 0.2 ± 0.2 | ||||||||
RUN215 | ADA-UCB-6c2cb422-1_1 | PET-UNK-8df914d1-4_1 | 3.1 ± 0.2 | 2.9 ± 0.2 | 0.2 ± 0.2 | ||||||||
RUN623 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-3_1 | 1.8 ± 0.2 | 2.0 ± 0.2 | 0.2 ± 0.2 | ||||||||
RUN199 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-976da9a6-1_1 | 1.5 ± 0.1 | 1.7 ± 0.2 | 0.1 ± 0.2 | ||||||||
RUN640 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-13_1 | 0.25 ± 0.04 | 0.1 ± 0.2 | 0.1 ± 0.2 | ||||||||
RUN46 | ADA-UCB-6c2cb422-1_1 | JAN-GHE-5a013bed-11_1 | 2.6 ± 0.2 | 2.5 ± 0.2 | 0.1 ± 0.2 | ||||||||
RUN189 | ADA-UCB-6c2cb422-1_1 | EDJ-MED-00c1612e-1_1 | 0.0 ± 0.1 | 0.1 ± 0.2 | 0.1 ± 0.2 | ||||||||
RUN646 | ADA-UCB-6c2cb422-1_1 | JIN-POS-6dc588a4-9_1 | 1.6 ± 0.1 | 1.6 ± 0.2 | 0.1 ± 0.2 | ||||||||
RUN152 | ADA-UCB-6c2cb422-1_1 | ADA-UCB-6c2cb422-1_1 | 0.02 ± 0.02 | 0.0 ± 0.2 | 0.0 ± 0.2 |