| Rank |
Microstate |
SMILES |
ΔG / kcal M-1 |
| 1901 |
MIC-UNK-d58dbb53-1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4)Cl)OC[C@@H]5CCCS5(=O)=O |
−7.0
± 0.2
|
| 1902 |
MIC-UNK-06e5f114-2_1
|
|
CS(=O)(=O)c1cccc(c1)NCc2ccc(cc2CC(=O)Nc3cncc4c3cccc4)Cl |
−7.0
± 0.2
|
| 1903 |
PET-UNK-9b23ef84-7_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CN(Cc4c3cc(c(c4)F)Cl)c5nnco5 |
−7.0
± 0.2
|
| 1904 |
JOH-SUS-a69c159d-2_1
|
|
c1ccc2c(c1)c(cnc2F)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−7.0
± 0.2
|
| 1905 |
ED_-GRI-5b13fbe2-1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC[NH2+]Cc5cc(no5)C(=O)[O-] |
−7.0
± 0.5
|
| 1906 |
ALP-POS-64a710fa-1_1
|
|
c1ccc2c(c1)cncc2CC(=O)N(CCC3CCCCC3)Cc4cccs4 |
−6.98
± 0.09
|
| 1907 |
PET-UNK-ab76d8f6-1_1
|
|
CO[C@]1(CCS(=O)(=O)c2c1cc(cc2)Cl)C(=O)Nc3cncc4c3ccc(c4)C#N |
−7.0
± 0.2
|
| 1908 |
PET-UNK-d9de6a0b-2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5CS(=O)(=O)C5 |
−7.0
± 0.2
|
| 1909 |
VLA-UNK-c65c1026-5_1
|
|
c1ccc2c(c1)cncc2N3C(=O)C[NH2+][C@@]4(C3=O)COc5c4cc(cc5)Cl |
−7.0
± 0.2
|
| 1910 |
MAK-UNK-83e0a0b4-3_2
|
|
c1ccc2c(c1)cncc2N(CCNC3C[NH2+]C3)C(=O)[C@H]4CCOc5c4cc(cc5)Cl |
−7.0
± 0.3
|
| 1911 |
DAR-DIA-0d514e7d-32_22
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3[C@@H]4C[C@H]4CO[C@@H]5[C@H]3C=C(C=C5)Cl |
−7.0
± 0.1
|
| 1912 |
MAT-POS-3b97339c-1_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@]5(CCSC5)O |
−7.0
± 0.2
|
| 1913 |
PET-UNK-689df078-2_1
|
|
c1ccc2c(c1)cncc2N3C(=O)CO[C@H](C3=O)c4cccc(c4)Cl |
−7.0
± 0.3
|
| 1914 |
NIR-THE-47736cde-1_1
|
|
C=CC(=O)N(c1cncc2c1cccc2)C(=O)[C@H]3COc4c3cc(cc4)Cl |
−7.0
± 0.2
|
| 1915 |
DAR-DIA-0f2f46c9-7_3
|
|
CNS(=O)(=O)[N@@]1CC[C@H](c2c1ccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.2
|
| 1916 |
MAT-POS-61f37a1a-10_1
|
|
COC(=O)c1cnc(cn1)Cn2ccc(n2)C[NH2+]C[C@@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.96
± 0.09
|
| 1917 |
MAT-POS-f7918075-1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−7.0
± 0.2
|
| 1918 |
RAL-THA-2d450e86-31_1
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cccc(c3)C(F)(F)F |
−6.96
± 0.10
|
| 1919 |
EDJ-MED-cf4b0d25-1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H](c3cccc(c3)Cl)NC(=O)COCC(=O)N4CCCC4 |
−6.96
± 0.09
|
| 1920 |
ED_-GRI-5b13fbe2-40_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC[C@H](C[NH3+])F |
−7.0
± 0.4
|
| 1921 |
BEN-DND-c852c98b-2_2
|
|
c1cc2cncc(c2cc1OC(F)(F)F)NC(=O)[C@H]3CCOc4c3cc(cc4)Cl |
−7.0
± 0.4
|
| 1922 |
MAT-POS-61f37a1a-1_4
|
|
CC(C)(C)OC(=O)N[C@H](CCO)C[NH2+]C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.95
± 0.09
|
| 1923 |
EDJ-MED-9e38fd34-5_1
|
|
C[C@]1(c2cc(c(cc2NC1=O)Cl)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.4
|
| 1924 |
MAT-POS-8293a91a-4_2
|
|
CNC(=O)C[N@H+]1Cc2ccc(cc2[C@@H](C1)C(=O)Nc3cncc4c3cccc4)Cl |
−7.0
± 0.2
|
| 1925 |
ALP-POS-e6e0c683-4_1
|
|
CS(=O)(=O)c1ccc2cncc(c2c1)NC(=O)[C@@H]3CS(=O)(=O)Cc4c3cc(cc4)Cl |
−7.0
± 0.3
|
| 1926 |
ALF-EVA-82cf4849-10_1
|
|
c1cc2cncc(c2cc1C[NH3+])NC(=O)[C@@H]3CCNc4c3cc(c(c4)Cl)Cl |
−6.9
± 0.2
|
| 1927 |
EDJ-MED-1981ceba-5_2
|
|
C[NH+]1CCN(CC1)S(=O)(=O)[N@]2Cc3ccc(cc3[C@@H](C2)C(=O)Nc4cncc5c4cccc5)Cl |
−6.9
± 0.3
|
| 1928 |
MAT-POS-fb82b63d-4_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3c4cc(ccc4CC[N@@H+]3CC5CC5)Cl |
−6.9
± 0.1
|
| 1929 |
ALP-POS-5bb456a5-1_10
|
|
C[C@H]1C[N@@](CC[C@@H]1NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)C |
−6.94
± 0.10
|
| 1930 |
MIC-UNK-0a05c952-2_1
|
|
c1ccc2c(c1)cncc2N3[C@@H](CC[C@@H](C3=O)c4cccc(c4)Cl)[C@@H]5CO5 |
−6.9
± 0.2
|
| 1931 |
MAT-POS-e6dd326d-11_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)C[NH2+]CC(=O)[O-] |
−6.9
± 0.3
|
| 1932 |
EDJ-MED-d203f206-36_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@](C5)(C#N)C(=O)N |
−6.9
± 0.4
|
| 1933 |
DAR-DIA-23e5a6a0-9_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4C[C@H]5CC6(CC6)C[NH2+]5)Cl |
−6.9
± 0.2
|
| 1934 |
DAR-DIA-0f2f46c9-4_2
|
|
CS(=O)(=O)[N@]1CC[C@@H](c2c1ccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.1
|
| 1935 |
MAT-POS-4223bc15-38_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CN(Cc4c3cc(cc4)Cl)C(=O)c5ncco5 |
−6.94
± 0.10
|
| 1936 |
ED_-GRI-5b13fbe2-34_2
|
|
C[N@@](CCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)CC(C(=O)N)(F)F |
−6.9
± 0.5
|
| 1937 |
MAT-POS-6344a35d-1_1
|
|
COc1cccc(n1)Oc2cc(cc(c2)Cl)NC(=O)Cc3cncc4c3cccc4 |
−6.94
± 0.09
|
| 1938 |
EDG-MED-ba1ac7b9-25_4
|
|
C[C@H]1CN(CC[N@H+]1CCO)C(=O)C[C@@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.94
± 0.08
|
| 1939 |
EDG-MED-90036822-27_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CO[C@H](CN)C(F)(F)F |
−6.9
± 0.6
|
| 1940 |
ALP-POS-fe871b40-1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4C#N)Cl |
−6.9
± 0.2
|
| 1941 |
MIC-UNK-cdc2493e-12_4
|
|
C[NH+](C)[C@H]1CC[C@H](C1)N(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
| 1942 |
MIC-UNK-cdc2493e-16_1
|
|
c1ccc2c(c1)cncc2NC(=O)N(CCc3ccco3)c4cccc(c4)Cl |
−6.9
± 0.3
|
| 1943 |
MAK-UNK-c749d764-15_6
|
|
C[C@H](N(c1cncc2c1cccc2)C(=O)C[C@@H]3CCC[C@H]([C@@H]3O)C(F)F)OCC4CCCCC4 |
−6.9
± 0.1
|
| 1944 |
MIC-UNK-c5a20098-2_1
|
|
c1ccc2c(c1)cncc2C(=O)C(C3CN(C3)c4cccc(c4)Cl)(F)F |
−6.9
± 0.5
|
| 1945 |
EDJ-MED-139368ae-5_2
|
|
C[NH+]1CCN(CC1)S(=O)(=O)[N@]2Cc3ccccc3[C@@H](C2)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.2
|
| 1946 |
JOH-UNI-21fd6073-1_2
|
|
c1ccc(cc1)S(=O)(=O)N(CC#N)C(=O)CN(c2cncc3c2cccc3)C(=O)[C@H]4COc5c4cc(cc5)Cl |
−6.9
± 0.1
|
| 1947 |
JAG-UCB-f37eaa14-4_2
|
|
c1ccc2c(c1)cncc2N3CC[C@@]4(C3=O)C[N@](c5c4cc(cc5)Cl)CC[NH2+]C6CC6 |
−6.9
± 0.2
|
| 1948 |
ALF-EVA-07677224-1_3
|
|
Cc1nc(ns1)S(=O)(=O)[N@@]2Cc3ccc(cc3[C@H](C2)C(=O)Nc4cncc5c4cccc5)Cl |
−6.9
± 0.2
|
| 1949 |
MAT-POS-dc2604c4-3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3C[N@@](Cc4c3cc(cc4)Cl)S(=O)(=O)CC5(CNC5)C#N |
−6.9
± 0.2
|
| 1950 |
RAL-THA-8416115c-14_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3CCN(c4c3cc(cc4)Cl)Cc5cn[nH]n5 |
−6.9
± 0.5
|
| 1951 |
DAR-DIA-0587064e-10_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3CCOc4c3cc(cc4OCCC(F)(F)F)Cl |
−6.93
± 0.08
|
| 1952 |
EDJ-MED-2f867453-1_2
|
|
C[C@]1(CNc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.92
± 0.10
|
| 1953 |
KAD-UNI-8a629cb0-1_1
|
|
CS(=O)(=O)[N@@]1CC[C@H](C1)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.4
|
| 1954 |
ALF-EVA-07677224-10_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3C[N@@](Cc4c3cc(cc4)Cl)S(=O)(=O)c5[nH]ncn5 |
−6.9
± 0.3
|
| 1955 |
KAD-UNI-cb0f2bbc-20_3
|
|
Cn1cc(cn1)N2CC[C@H](C2)C[NH2+]C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.9
± 0.1
|
| 1956 |
KAD-UNI-cb0f2bbc-5_1
|
|
CNC(=O)COc1ccc(cc1OC)C[NH2+]C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.1
|
| 1957 |
BEN-DND-f2e727cd-4_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3COCc4c3cc(cc4)Cl |
−6.92
± 0.10
|
| 1958 |
EDG-MED-ba1ac7b9-28_3
|
|
C[N@@H+](CCO)C1CCN(CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.92
± 0.09
|
| 1959 |
ALP-POS-347519b5-3_9
|
|
CS(=O)(=O)[N@@]1C[C@@H]2[C@@H]3CC[C@H]([C@@H]2[C@@H](C1)C(=O)Nc4cncc5c4cccc5)O3 |
−6.9
± 0.3
|
| 1960 |
MIC-UNK-25b9c114-2_2
|
|
c1ccc2c(c1)cncc2C(=O)N3CC(=O)N(C[C@H]3CNS(=O)(=O)N)c4cccc(c4)Cl |
−6.9
± 0.2
|
| 1961 |
MAT-POS-61f37a1a-13_3
|
|
Cc1[nH]c(c[nH+]1)C[N@@H+]2Cc3ccc(cc3[C@H](C2)C(=O)Nc4cncc5c4cc(cc5)F)Cl |
−6.92
± 0.10
|
| 1962 |
DAR-DIA-0d514e7d-17_1
|
|
C[C@H]1COc2c(cc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)c5cc(cc(c5)F)F |
−6.9
± 0.4
|
| 1963 |
DAR-DIA-6be260fc-4_1
|
|
CC(C)[C@H]1CN(C(=O)[C@@]12CNc3c2cc(cc3)Cl)c4cncc5c4cccc5 |
−6.9
± 0.3
|
| 1964 |
EDJ-MED-1981ceba-4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3C[N@@](Cc4c3cc(cc4)Cl)S(=O)(=O)N5CC(C5)C#N |
−6.9
± 0.2
|
| 1965 |
EDJ-MED-37aac4bd-2_2
|
|
COC[C@]1(CCOc2c1cc(c(c2)Cl)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.91
± 0.09
|
| 1966 |
ALP-POS-347519b5-3_28
|
|
CS(=O)(=O)[N@]1C[C@H]2[C@@H]3CC[C@H]([C@H]2[C@@H](C1)C(=O)Nc4cncc5c4cccc5)O3 |
−6.9
± 0.3
|
| 1967 |
MAT-POS-4223bc15-6_1
|
|
CCS(=O)(=O)[N@@]1Cc2ccc(cc2[C@@H](C1)C(=O)Nc3cncc4c3cccc4)Cl |
−6.91
± 0.10
|
| 1968 |
MAT-POS-4223bc15-11_15
|
|
C[C@@H]1CC[N@](C1)S(=O)(=O)[N@]2Cc3ccc(cc3[C@H](C2)C(=O)Nc4cncc5c4cccc5)Cl |
−6.91
± 0.09
|
| 1969 |
KAD-UNI-cb0f2bbc-20_2
|
|
Cn1cc(cn1)N2CC[C@@H](C2)C[NH2+]C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.9
± 0.2
|
| 1970 |
MIC-UNK-5a93dd5f-3_12
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H](c3cccc(c3)Cl)[N@H+]4CC[C@@H]5CCCC[C@H]5C4 |
−6.9
± 0.5
|
| 1971 |
MAT-POS-61f37a1a-8_2
|
|
Cc1c(c(n(n1)C)N2CCOCC2)C[NH2+]C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.91
± 0.09
|
| 1972 |
KAD-UNI-b13decd3-1_2
|
|
Cn1cc(cn1)N2CC[C@@H](C2)C[NH2+]C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.91
± 0.10
|
| 1973 |
ALP-POS-5bb456a5-7_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[NH+](CC5)[C@H]6CCOC6 |
−6.91
± 0.10
|
| 1974 |
PET-UNK-12d8d43f-1_1
|
|
c1ccc2c(c1)cncc2N(C=O)C(=O)Cc3cccc(c3)Cl |
−6.9
± 0.3
|
| 1975 |
DAR-DIA-0f7b7cd9-10_1
|
|
c1ccc2c(c1)cncc2N3CCC(=O)N(C3=O)c4ccccc4Cl |
−6.9
± 0.3
|
| 1976 |
MIC-UNK-9582b2c5-3_4
|
|
CC(=O)N1CC[C@H]2[C@H](C1)CN(C(=O)N2c3cccc(c3)Cl)c4cncc5c4cccc5 |
−6.9
± 0.1
|
| 1977 |
ALP-POS-c3a96089-1_1
|
|
Cc1ccc(cc1)N(Cc2cscn2)C(=O)Cc3cncc4c3cccc4 |
−6.90
± 0.10
|
| 1978 |
EDJ-MED-6864a934-8_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cccc6n5nnc6 |
−6.9
± 0.3
|
| 1979 |
MAT-POS-4223bc15-8_8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3C[N@](Cc4c3cc(cc4)Cl)S(=O)(=O)[C@H]5CCOC5 |
−6.90
± 0.09
|
| 1980 |
MAK-UNK-ffc90da7-1_4
|
|
C[C@H](C[NH2+]CCCO)[C@H](c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3 |
−6.9
± 0.1
|
| 1981 |
MAK-UNK-c749d764-18_2
|
|
CC(C)SCN(c1cncc2c1cccc2)C(=O)C[C@H]3CCC[C@@H]([C@@H]3O)C(F)F |
−6.9
± 0.3
|
| 1982 |
MIC-UNK-5a93dd5f-5_7
|
|
CC(=O)N[C@@H]1CC[N@H+](C1)[C@H](c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
| 1983 |
MIC-UNK-5a93dd5f-9_6
|
|
CN(C)[C@H]1CC[N@@H+](C1)[C@H](c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
| 1984 |
MIC-UNK-5a93dd5f-5_8
|
|
CC(=O)N[C@H]1CC[N@H+](C1)[C@H](c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
| 1985 |
NAU-LAT-4ce8bf23-3_1
|
|
CC(=O)N[C@@H](c1cncc2c1cccc2)C(=O)Nc3cccc(c3)Cl |
−6.9
± 0.4
|
| 1986 |
DAR-DIA-4987d2cd-4_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3c4cc(ccc4CN3c5c(c(=O)c5=O)[O-])Cl |
−6.9
± 0.2
|
| 1987 |
RAL-THA-b9d6aec1-2_1
|
|
CNS(=O)(=O)c1ccc2cncc(c2c1)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−6.9
± 0.3
|
| 1988 |
MAK-UNK-c749d764-15_7
|
|
C[C@@H](N(c1cncc2c1cccc2)C(=O)C[C@H]3CCC[C@H]([C@@H]3O)C(F)F)OCC4CCCCC4 |
−6.9
± 0.2
|
| 1989 |
DAR-DIA-9e4459de-13_8
|
|
c1cc2c(c(c1)NCOCCOc3ccc4c(c3)cncc4NC(=O)[C@@H]5CCOc6c5cc(cc6)Cl)c(n(c2O)[C@H]7CCC(=O)NC7=O)O |
−6.9
± 0.5
|
| 1990 |
MAK-UNK-c749d764-5_1
|
|
c1ccc2c(c1)cncc2N(CO)C(=O)C[C@@H]3CCC[C@@H]([C@@H]3O)C(F)F |
−6.9
± 0.4
|
| 1991 |
EDG-MED-ba1ac7b9-27_3
|
|
C[C@@H]1C[N@H+](CCN1C(=O)C[C@@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CCO |
−6.88
± 0.08
|
| 1992 |
KAD-UNI-877d7bed-8_1
|
|
CC(=O)N1CCN(CC1)C(=O)COc2cc(cc3c2OCC[C@@H]3C(=O)Nc4cncc5c4cccc5)Cl |
−6.9
± 0.1
|
| 1993 |
ALP-UNI-8e43a71e-12_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccn(n5)[C@H]6CCNC6=O |
−6.9
± 0.2
|
| 1994 |
MIC-UNK-5a93dd5f-8_1
|
|
C[NH+](C)C1CC[NH+](CC1)[C@@H](c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
| 1995 |
ALP-POS-347519b5-3_40
|
|
CS(=O)(=O)[N@]1C[C@H]2[C@H]3CC[C@@H]([C@@H]2[C@H](C1)C(=O)Nc4cncc5c4cccc5)O3 |
−6.88
± 0.08
|
| 1996 |
JOH-UNI-a38a7bdd-6_3
|
|
c1ccc2c(c1)cncc2N(C(=O)Cc3cccc(c3)Cl)C(=O)[C@@H]4C[C@H]4C(F)(F)F |
−6.9
± 0.2
|
| 1997 |
EDG-MED-ba1ac7b9-10_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC[C@@H]5c6ccn[nH]6 |
−6.88
± 0.10
|
| 1998 |
DAR-DIA-0f2f46c9-13_1
|
|
CN(C)S(=O)(=O)[N@@]1CC[C@@H](c2c1ccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.2
|
| 1999 |
ALP-UNI-dbbfd3db-10_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5cc(c(=O)[nH]c5=O)Cl |
−6.9
± 0.1
|
| 2000 |
EDG-MED-ba1ac7b9-14_5
|
|
C[N@@]1CCN(C[C@@H]1C#N)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.5
|