Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2501 |
ERI-UCB-8d4e5055-2
|
|
c1cc2cncc(c2cc1CN3CCNCC3)NC(=O)[C@@H]4CCOc5c4cc(cc5)Cl |
−4.0
± 0.3
|
2.9
± 0.3
|
2502 |
EDG-MED-90036822-43
|
|
Cc1cncn1CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−4.0
± 0.6
|
2.9
± 0.4
|
2503 |
EDJ-MED-670ad2ee-4
|
|
C[C@]1(CN(Cc2c1cc(cc2)Cl)S(=O)(=O)C)C(=O)Nc3cncc4c3cc(cc4)S(=O)(=O)C |
−4.0
± 0.6
|
2.9
± 0.5
|
2504 |
PET-UNK-1320d94d-13
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H](c3ccc(c(c3)Cl)Cl)NC(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCOCC5 |
−4.0
± 0.5
|
2.9
± 0.4
|
2505 |
CHO-MSK-5891c1ff-1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC[C@@H]5C[C@H](CO5)CO |
−4.0
± 0.6
|
2.9
± 0.4
|
2506 |
EDJ-MED-a6bd50ad-1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CC(=O)Nc4c3cc(cc4)Cl |
−4.0
± 0.4
|
2.9
± 0.3
|
2507 |
ALF-EVA-5b152d2f-5
|
|
c1cc2c(cc1C3CCC3)cncc2NC(=O)[C@@H]4CCOc5c4cc(cc5)Cl |
−3.9
± 0.3
|
2.9
± 0.2
|
2508 |
MAT-POS-d8472c4f-2
|
|
COC(=O)[C@H]1CC[C@H](O1)CNC(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−3.9
± 0.3
|
2.9
± 0.2
|
2509 |
ALF-EVA-82cf4849-8
|
|
COC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cc(cc4)S(=O)(=O)N |
−3.9
± 0.4
|
2.8
± 0.3
|
2510 |
LON-WEI-5e7d1b3e-60
|
|
CC1CCN(CC1)CCCNC(=O)Nc2cn(c(=O)c3c2cccc3)CC(C)C |
−3.9
± 0.6
|
2.8
± 0.5
|
2511 |
MIC-UNK-a28eba03-2
|
|
CN1CCN(CC1)C(=O)Cc2cncc3c2cccc3 |
−3.9
± 0.5
|
2.8
± 0.4
|
2512 |
RUB-POS-1325a9ea-5
|
|
Cc1cccc2c1cncc2NC(=O)Cc3cccc(c3)Cl |
−3.86
± 0.08
|
2.81
± 0.05
|
2513 |
EDJ-MED-923a35c2-2
|
|
COC1(CN(Cc2c1cc(c(c2)F)Cl)S(=O)(=O)C)C(=O)Nc3cncc4c3cc(cc4)S(=O)(=O)C |
−3.9
± 0.3
|
2.8
± 0.2
|
2514 |
ALP-POS-2da19ca7-4
|
|
Cn1c(nnn1)C2CCN(CC2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−3.9
± 0.4
|
2.8
± 0.3
|
2515 |
JOH-UNI-ee5ed7c8-1
|
|
C#CC(=O)c1cccc2c1c(cnc2)NC(=O)Cc3cccc(c3)Cl |
−3.8
± 0.5
|
2.8
± 0.4
|
2516 |
ALP-UNI-dbbfd3db-2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5c(=O)c(=O)n6c(n5)CCC6 |
−3.8
± 0.2
|
2.8
± 0.2
|
2517 |
PET-UNK-ac320b15-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H](c3cccc(c3)Cl)NC(=O)[C@@H]4CC[C@H](O4)C(=O)N5CCCC5 |
−3.8
± 0.4
|
2.8
± 0.3
|
2518 |
PET-UNK-9bf1291a-4
|
|
CO[C@]1(CN(Cc2c1cc(cc2)Cl)CC#N)C(=O)Nc3cncc4c3cc(cc4)F |
−3.8
± 0.3
|
2.8
± 0.2
|
2519 |
LON-WEI-5e7d1b3e-30
|
|
CC(C)Cn1cc(c2ccccc2c1=O)NC(=O)Nc3nc4ccccc4s3 |
−3.8
± 0.2
|
2.8
± 0.2
|
2520 |
EDG-MED-90036822-75
|
|
CN1C[C@@H](C[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)F |
−3.8
± 0.4
|
2.8
± 0.3
|
2521 |
EDG-MED-90036822-16
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H](CF)O |
−3.8
± 0.5
|
2.8
± 0.3
|
2522 |
ALP-POS-82da25a3-2
|
|
c1cc2cncc(c2cc1CO)NC(=O)C3CCOc4c3cc(cc4)Cl |
−3.8
± 0.2
|
2.8
± 0.2
|
2523 |
PET-UNK-1320d94d-4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H](c3cccc(c3)Cl)NC(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCOCC5 |
−3.8
± 0.5
|
2.8
± 0.4
|
2524 |
BEN-DND-a02b439d-13
|
|
CO[C@]1(CNCc2c1cc(c(c2)Cl)Cl)C(=O)Nc3cncc4c3cccc4 |
−3.8
± 0.2
|
2.7
± 0.2
|
2525 |
PET-UNK-1320d94d-21
|
|
CN(C)C(=O)[C@H]1CC[C@H](O1)C(=O)N(C)[C@H](c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−3.8
± 0.3
|
2.7
± 0.2
|
2526 |
CHO-MSK-5891c1ff-5
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)[C@@H]5CCS(=O)(=O)C5 |
−3.7
± 0.5
|
2.7
± 0.4
|
2527 |
PET-UNK-2c6614b6-5
|
|
c1cc2c(cc1F)cncc2NC(=O)[C@@H]3CCS(=O)(=O)c4c3cc(cc4)Cl |
−3.7
± 0.4
|
2.7
± 0.3
|
2528 |
PET-UNK-1e13ef09-1
|
|
c1cc2c(cc1F)cncc2NC(=O)[C@@H]3CS(=O)(=O)Cc4c3cc(cc4)Cl |
−3.7
± 0.3
|
2.7
± 0.2
|
2529 |
LON-WEI-5e7d1b3e-20
|
|
CC(C)Cn1cc(c2ccccc2c1=O)NC(=O)NCCc3c[nH]c4c3cccc4 |
−3.7
± 0.4
|
2.7
± 0.3
|
2530 |
RAL-THA-1d44ff04-12
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)Oc4ccc[nH]c4=O |
−3.7
± 0.3
|
2.7
± 0.2
|
2531 |
CHO-MSK-5891c1ff-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NC5CC5 |
−3.6
± 0.6
|
2.6
± 0.5
|
2532 |
PET-UNK-b78139fa-7
|
|
c1cc2cncc(c2cc1F)NC(=O)[C@@H]3CS(=O)(=O)c4c3cc(cc4)Cl |
−3.6
± 0.5
|
2.6
± 0.3
|
2533 |
PET-UNK-1b92fa34-8
|
|
CO[C@]1(CS(=O)(=O)Cc2c1cc(c(c2)F)Cl)C(=O)Nc3cncc4c3cc(cc4)F |
−3.6
± 0.4
|
2.6
± 0.3
|
2534 |
ALP-UNI-0676e700-17
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(nc5)c6n[nH]nn6 |
−3.6
± 0.3
|
2.6
± 0.2
|
2535 |
ALP-UNI-3496895b-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)CCC#N |
−3.6
± 0.3
|
2.6
± 0.2
|
2536 |
EDG-MED-90036822-85
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5C[C@H]([C@@H](C5)F)O |
−3.6
± 0.5
|
2.6
± 0.4
|
2537 |
JOH-UNI-50ce7ec3-1
|
|
C=CS(=O)(=O)N(c1cncc2c1cccc2)C(=O)Cc3cccc(c3)Cl |
−3.6
± 0.6
|
2.6
± 0.4
|
2538 |
DAR-DIA-ecdbc7dd-6
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCNc4c3cc(cc4)Cl)Cn5cnc6c5cccc6 |
−3.5
± 0.1
|
2.59
± 0.09
|
2539 |
PET-UNK-1320d94d-25
|
|
CN([C@H](c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3)C(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCC5 |
−3.5
± 0.4
|
2.6
± 0.3
|
2540 |
PET-UNK-1320d94d-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H](c3cccc(c3)Cl)NC(=O)[C@@H]4C[C@@H](O4)C(=O)N5CCCC5 |
−3.5
± 0.5
|
2.5
± 0.4
|
2541 |
EDG-MED-10fcb19e-5
|
|
COC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cc(cc4)c5c[nH]nc5 |
−3.5
± 0.2
|
2.5
± 0.2
|
2542 |
RUB-POS-1325a9ea-9
|
|
COc1cccc2c1c(cnc2)NC(=O)Cc3cccc(c3)Cl |
−3.5
± 0.1
|
2.52
± 0.10
|
2543 |
PET-UNK-6314f867-3
|
|
c1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2c(ccc3)C#N |
−3.4
± 0.5
|
2.5
± 0.4
|
2544 |
ALP-UNI-0676e700-3
|
|
Cc1cc(no1)NC(=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−3.4
± 0.3
|
2.5
± 0.2
|
2545 |
PET-UNK-6314f867-1
|
|
c1cc2c(cc1C#N)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−3.4
± 0.1
|
2.51
± 0.09
|
2546 |
RAL-THA-2d450e86-21
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cccc(c3C#N)Cl |
−3.4
± 0.6
|
2.5
± 0.4
|
2547 |
JOH-UNI-3fc3434e-2
|
|
c1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2c(ccc3)C(=O)/C=C/C#N |
−3.4
± 0.6
|
2.5
± 0.4
|
2548 |
ED_-GRI-5b13fbe2-13
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC[C@@H]5CN[C@H](CN5)CO |
−3.4
± 0.1
|
2.5
± 0.1
|
2549 |
MAT-POS-8293a91a-8
|
|
c1cc2cncc(c2cc1F)N3CCC4(C3=O)COc5c4cc(cc5)Cl |
−3.4
± 0.2
|
2.5
± 0.2
|
2550 |
MAT-POS-5369c344-2
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3cc(cc4OCCC(F)(F)F)Cl |
−3.39
± 0.10
|
2.47
± 0.07
|
2551 |
PET-UNK-03fd2068-1
|
|
c1cc2c(cc1F)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−3.4
± 0.3
|
2.4
± 0.2
|
2552 |
CHO-MSK-5891c1ff-10
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCC5 |
−3.3
± 0.5
|
2.4
± 0.3
|
2553 |
PET-UNK-ac320b15-2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H](c3ccc(cc3)Cl)NC(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCCC5 |
−3.3
± 0.2
|
2.4
± 0.2
|
2554 |
MIC-UNK-50cce87d-2
|
|
c1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2c(ccc3)Cl |
−3.3
± 0.2
|
2.4
± 0.1
|
2555 |
EDG-MED-90036822-15
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CO)F |
−3.3
± 0.7
|
2.4
± 0.5
|
2556 |
PET-UNK-1e13ef09-2
|
|
CS(=O)(=O)c1ccc2cncc(c2c1)NC(=O)[C@@H]3CS(=O)(=O)Cc4c3cc(cc4)Cl |
−3.3
± 0.3
|
2.4
± 0.2
|
2557 |
BEN-DND-d6f8d3c6-1
|
|
c1ccc2c(c1)cncc2NC(=O)C3CNS(=O)(=O)c4c3cc(cc4)Cl |
−3.2
± 0.3
|
2.4
± 0.2
|
2558 |
EDG-MED-90036822-66
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn[nH]c5F |
−3.2
± 0.7
|
2.4
± 0.5
|
2559 |
PET-UNK-d61f3ea6-3
|
|
CC(C)(C#N)S(=O)(=O)N1Cc2ccc(cc2[C@@H](C1)C(=O)Nc3cncc4c3cccc4)Cl |
−3.2
± 0.2
|
2.3
± 0.2
|
2560 |
KAD-UNI-cb0f2bbc-23
|
|
CNS(=O)(=O)c1cc(ccc1F)CNC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−3.2
± 0.1
|
2.33
± 0.09
|
2561 |
BEN-DND-a02b439d-1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CN(Cc4c3cc(c(c4)Cl)Cl)CC(F)(F)F |
−3.2
± 0.1
|
2.32
± 0.09
|
2562 |
ALF-EVA-82cf4849-13
|
|
COC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cc(cc4)C5COC5 |
−3.2
± 0.4
|
2.3
± 0.3
|
2563 |
EDG-MED-90036822-67
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(c5cnc[nH]5)(F)F |
−3.1
± 0.5
|
2.3
± 0.4
|
2564 |
JOH-UNI-3fc3434e-13
|
|
CN(c1cncc2c1c(ccc2)CC(F)(F)F)C(=O)Cc3cccc(c3)Cl |
−3.1
± 0.4
|
2.3
± 0.3
|
2565 |
PET-UNK-1320d94d-29
|
|
CN([C@H](c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3)C(=O)[C@@H]4CCC[C@@H](O4)C(=O)N5CCCC5 |
−3.1
± 0.4
|
2.2
± 0.3
|
2566 |
VLA-UCB-34f3ed0c-13
|
|
c1ccc2c(c1)cncc2NC(=O)N(CCN3CCNCC3)c4cccc(c4)Cl |
−3.0
± 0.7
|
2.2
± 0.5
|
2567 |
ALP-POS-5bb456a5-5
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)c6n[nH]nn6 |
−3.0
± 0.3
|
2.2
± 0.2
|
2568 |
MAT-POS-b5746674-97
|
|
CCOC(=O)N1CCC(CC1)NC(=O)Nc2cn(c(=O)c3c2cccc3)C |
−3.0
± 0.4
|
2.2
± 0.3
|
2569 |
DAR-DIA-ecdbc7dd-17
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCNc4c3cc(cc4)Cl)CNC(=O)C5CC5 |
−2.9
± 0.2
|
2.1
± 0.1
|
2570 |
EDJ-MED-4c7486ba-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cnc[nH]5 |
−2.9
± 0.7
|
2.1
± 0.5
|
2571 |
DAR-DIA-0d514e7d-34
|
|
C[C@@H]1[C@@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−2.9
± 0.2
|
2.1
± 0.1
|
2572 |
NAU-LAT-2fed8305-7
|
|
c1ccc2c(c1)cncc2NC(=O)C3(COC3)c4cccc(c4)Cl |
−2.8
± 0.2
|
2.1
± 0.1
|
2573 |
DAR-DIA-b4e9dd8d-2
|
|
COC(=O)/C=C/C(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CNc4c3cc(cc4)Cl |
−2.8
± 0.2
|
2.0
± 0.2
|
2574 |
KAD-UNI-cb0f2bbc-6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNCc5ccc(nc5)n6ccc(n6)C(=O)N |
−2.8
± 0.1
|
2.01
± 0.09
|
2575 |
KAD-UNI-8a629cb0-14
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@@H]6C[C@H]5C[C@H]6O |
−2.7
± 0.5
|
2.0
± 0.4
|
2576 |
EDJ-MED-ee07cf00-2
|
|
Cc1c(c(=O)n2c(n1)cc[nH]2)CC(=O)NC(c3cccc(c3)Cl)C(=O)Nc4cncc5c4cccc5 |
−2.7
± 0.2
|
2.0
± 0.1
|
2577 |
MIC-UNK-50cce87d-1
|
|
c1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2c(ccc3)F |
−2.7
± 0.1
|
1.93
± 0.09
|
2578 |
EDJ-MED-d203f206-25
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@@H](C5)C#N |
−2.7
± 0.4
|
1.9
± 0.3
|
2579 |
EDJ-MED-670ad2ee-2
|
|
CO[C@]1(CN(Cc2c1cc(c(c2)F)Cl)S(=O)(=O)C)C(=O)Nc3cncc4c3cccc4 |
−2.6
± 0.6
|
1.9
± 0.4
|
2580 |
PET-UNK-03fd2068-8
|
|
CO[C@]1(CCOc2c1cc(c(c2)F)Cl)C(=O)Nc3cncc4c3ccc(c4)F |
−2.6
± 0.4
|
1.9
± 0.3
|
2581 |
ED_-GRI-5b13fbe2-28
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCn5c(c(nn5)CN)C(F)F |
−2.6
± 0.4
|
1.9
± 0.3
|
2582 |
DAR-DIA-076fb6ea-5
|
|
c1ccc2c(c1)cncc2N(C#CC#N)C(=O)Cc3cccc(c3)Cl |
−2.6
± 0.3
|
1.9
± 0.2
|
2583 |
ED_-GRI-5b13fbe2-68
|
|
C[C@@H](CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N |
−2.6
± 0.7
|
1.9
± 0.5
|
2584 |
ERI-UCB-8d4e5055-4
|
|
CS(=O)(=O)c1ccc2cncc(c2c1)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−2.6
± 0.5
|
1.9
± 0.3
|
2585 |
MIC-UNK-37660950-1
|
|
CS(=O)(=O)c1cccc(c1)CNc2ccc(cc2CC(=O)Nc3cncc4c3cccc4)Cl |
−2.5
± 0.5
|
1.8
± 0.3
|
2586 |
VLA-UNK-8e76d113-2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCNc4c3cc(c(c4C#N)Cl)Cl |
−2.5
± 0.2
|
1.8
± 0.2
|
2587 |
EDJ-MED-9e38fd34-3
|
|
C[C@@]1(c2cc(ccc2NC1=O)Cl)C(=O)Nc3cncc4c3cccc4 |
−2.5
± 0.3
|
1.8
± 0.2
|
2588 |
DAR-DIA-0587064e-2
|
|
CCCOc1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2cccc3 |
−2.5
± 0.1
|
1.80
± 0.09
|
2589 |
PET-UNK-1320d94d-17
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H](c3ccc(c(c3)Cl)Cl)NC(=O)[C@@H]4C[C@@H](O4)C(=O)N5CCCC5 |
−2.4
± 0.2
|
1.7
± 0.2
|
2590 |
PET-UNK-1320d94d-19
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H](c3ccc(c(c3)Cl)Cl)NC(=O)[C@@H]4CCC[C@@H](O4)C(=O)N5CCCC5 |
−2.4
± 0.4
|
1.7
± 0.3
|
2591 |
RUB-POS-1325a9ea-17
|
|
c1ccc2c(c1)c(cnc2F)NC(=O)Cc3cccc(c3)Cl |
−2.4
± 0.1
|
1.72
± 0.09
|
2592 |
KAD-UNI-8a629cb0-24
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC6(C5)CS(=O)(=O)C6 |
−2.3
± 0.4
|
1.7
± 0.3
|
2593 |
JOH-UNI-6fede743-4
|
|
c1ccc2c(c1)cnc(c2NC(=O)Cc3cccc(c3)Cl)O |
−2.3
± 0.4
|
1.7
± 0.3
|
2594 |
MAT-POS-45b13633-5
|
|
COC(=O)CC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−2.3
± 0.1
|
1.66
± 0.10
|
2595 |
ALP-UNI-3496895b-16
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5ccc(cc5)S(=O)(=O)N |
−2.2
± 0.3
|
1.6
± 0.2
|
2596 |
PET-UNK-0cc03aae-5
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCC#N |
−2.2
± 0.3
|
1.6
± 0.2
|
2597 |
EDJ-MED-fcba3f31-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5=NCCO5 |
−2.2
± 0.4
|
1.6
± 0.3
|
2598 |
ED_-GRI-5b13fbe2-70
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC[C@H]5C[C@H]5N |
−2.2
± 0.6
|
1.6
± 0.4
|
2599 |
NAU-LAT-30527ac5-1
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc4c3[nH]cc4)Cl |
−2.1
± 0.5
|
1.5
± 0.4
|
2600 |
ED_-GRI-5b13fbe2-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCOCCNCCN |
−1.9
± 0.2
|
1.4
± 0.1
|