Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2401 |
DAR-DIA-e7614d05-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4)Cl)OC(F)(F)F |
−4.6
± 0.4
|
3.4
± 0.3
|
2402 |
PET-UNK-bcc8fd08-3
|
|
[2H]C([2H])([2H])O[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3ccc(c4)F |
−4.6
± 0.3
|
3.4
± 0.2
|
2403 |
VLA-UNK-f702bf1c-6
|
|
c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CCOc5c4cc(cc5)Cl)N(C3=O)CC6CCCCC6 |
−4.6
± 0.3
|
3.4
± 0.2
|
2404 |
EDG-MED-90036822-63
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(F)F |
−4.6
± 0.5
|
3.4
± 0.4
|
2405 |
EDJ-MED-d203f206-13
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5cnncn5 |
−4.6
± 0.4
|
3.3
± 0.3
|
2406 |
EDG-MED-ba1ac7b9-29
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCOc4c3cc(cc4)Cl)CC(=O)N(Cc5ccc(cn5)O)C6CC6 |
−4.6
± 0.2
|
3.3
± 0.1
|
2407 |
PET-UNK-1320d94d-24
|
|
CN([C@@H](c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3)C(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCOCC5 |
−4.6
± 0.3
|
3.3
± 0.3
|
2408 |
MAT-POS-e6dd326d-12
|
|
CNC(=O)NCC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.6
± 0.3
|
3.3
± 0.2
|
2409 |
RAL-THA-e002e396-8
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCOc4c3cc(cc4)Cl)CS(=O)(=O)CCO |
−4.6
± 0.1
|
3.33
± 0.09
|
2410 |
MIC-UNK-37660950-4
|
|
CS(=O)(=O)N1CCC(C1)CNc2ccc(cc2CC(=O)Nc3cncc4c3cccc4)Cl |
−4.6
± 0.3
|
3.3
± 0.2
|
2411 |
ROB-UNI-6ee2df8c-1
|
|
c1cc2cncc(c2cc1Cl)NC(=O)[C@@H]3CCOc4c3cc(c(c4)Cl)Cl |
−4.6
± 0.3
|
3.3
± 0.2
|
2412 |
JOH-UNI-f51e3bbc-3
|
|
c1ccc2c(c1)cnc(c2NC(=O)C3CCOc4c3cc(cc4)Cl)O |
−4.6
± 0.2
|
3.3
± 0.1
|
2413 |
DAR-DIA-0d514e7d-8
|
|
C[C@H]1COc2ccc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)C#N |
−4.5
± 0.3
|
3.3
± 0.2
|
2414 |
EDJ-MED-ee07cf00-13
|
|
Cc1nc2n(n1)C[C@@H](CC2)C(=O)NC(c3cccc(c3)Cl)C(=O)Nc4cncc5c4cccc5 |
−4.5
± 0.3
|
3.3
± 0.2
|
2415 |
MAT-POS-b5746674-100
|
|
CC(C)Cn1cc(c2ccccc2c1=O)NC(=O)NCCCN3CCCC3=O |
−4.5
± 0.3
|
3.3
± 0.2
|
2416 |
LON-WEI-5e7d1b3e-47
|
|
CCc1ccccc1N(CC)C(=O)Nc2cn(c(=O)c3c2cccc3)C |
−4.5
± 0.6
|
3.3
± 0.4
|
2417 |
ALP-UNI-76695c4f-9
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)CC(CO)(F)F |
−4.5
± 0.3
|
3.3
± 0.2
|
2418 |
ALP-UNI-3496895b-3
|
|
CC(=O)N1CC2CC1CN2C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−4.5
± 0.3
|
3.3
± 0.2
|
2419 |
PET-UNK-8c422e11-2
|
|
CCC(c1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2cccc3)(F)F |
−4.5
± 0.5
|
3.3
± 0.3
|
2420 |
ALF-EVA-82cf4849-6
|
|
CNc1ccc2c(c1)cncc2NC(=O)[C@@H]3CCNc4c3cc(c(c4)Cl)Cl |
−4.5
± 0.2
|
3.3
± 0.2
|
2421 |
EDG-MED-90036822-20
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(c5cnc[nH]5)F |
−4.5
± 0.5
|
3.3
± 0.3
|
2422 |
MIC-UNK-16ccb665-1
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)OC(F)F |
−4.5
± 0.3
|
3.3
± 0.2
|
2423 |
EDG-MED-90036822-62
|
|
CN(C)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.5
± 0.4
|
3.3
± 0.3
|
2424 |
JOH-UNI-ee5ed7c8-5
|
|
CN(c1cncc2c1c(ccc2)C(=O)C#C)C(=O)Cc3cccc(c3)Cl |
−4.5
± 0.4
|
3.3
± 0.3
|
2425 |
EDG-MED-90036822-56
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC#N |
−4.5
± 0.5
|
3.3
± 0.3
|
2426 |
KAD-UNI-cb0f2bbc-4
|
|
Cn1c(c(c(=O)n(c1=O)C)CNC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)N6CCCCC6 |
−4.5
± 0.1
|
3.27
± 0.10
|
2427 |
EDG-MED-90036822-21
|
|
CN(C)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.5
± 0.5
|
3.3
± 0.4
|
2428 |
KAD-UNI-8a629cb0-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cc(sc5)S(=O)(=O)N |
−4.5
± 0.4
|
3.3
± 0.3
|
2429 |
PET-UNK-49566573-2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCC(=O)N5CCC5 |
−4.5
± 0.2
|
3.3
± 0.1
|
2430 |
ALP-UNI-3735e77e-3
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3cc(c(c4)Cl)F |
−4.5
± 0.5
|
3.2
± 0.3
|
2431 |
ED_-GRI-5b13fbe2-44
|
|
Cc1c(nnn1CC(CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)(F)F)CN |
−4.5
± 0.6
|
3.2
± 0.5
|
2432 |
PET-UNK-1b92fa34-6
|
|
CO[C@]1(CS(=O)(=O)Cc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cc(cc4)F |
−4.5
± 0.3
|
3.2
± 0.2
|
2433 |
MIC-UNK-5d22d78d-2
|
|
CC(=CCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C |
−4.5
± 0.2
|
3.2
± 0.2
|
2434 |
VLA-MRT-a639d434-3
|
|
c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CNCc5c4cc(cc5)Cl)NC3=O |
−4.5
± 0.3
|
3.2
± 0.3
|
2435 |
PET-UNK-9b23ef84-2
|
|
CC(=O)N1Cc2ccc(cc2[C@@H](C1)C(=O)Nc3cncc4c3cccc4)Cl |
−4.5
± 0.4
|
3.2
± 0.3
|
2436 |
ALF-EVA-82cf4849-1
|
|
CNc1cc2c(cc1Cl)[C@@H](CCN2)C(=O)Nc3cncc4c3cccc4 |
−4.5
± 0.4
|
3.2
± 0.3
|
2437 |
EDG-MED-ba1ac7b9-6
|
|
CC(C)N(CC#N)C(=O)CC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.4
± 0.2
|
3.2
± 0.2
|
2438 |
DAR-DIA-6be260fc-6
|
|
c1ccc2c(c1)cncc2N3CCCC4(C3=O)CNc5c4cc(cc5)Cl |
−4.4
± 0.6
|
3.2
± 0.4
|
2439 |
PET-UNK-3bb57da2-3
|
|
COCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.4
± 0.3
|
3.2
± 0.2
|
2440 |
EDG-MED-90036822-31
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5[nH]ccn5 |
−4.4
± 0.4
|
3.2
± 0.3
|
2441 |
ALP-POS-a9ad2217-1
|
|
c1ccc2c(c1)cncc2NC(=O)C(c3ccc(c(c3)Cl)Cl)NC(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCCC5 |
−4.4
± 0.3
|
3.2
± 0.2
|
2442 |
PET-UNK-022eab87-2
|
|
CO[C@]1(CS(=O)(=O)c2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.4
± 0.3
|
3.2
± 0.2
|
2443 |
ALF-EVA-a24cc7ce-7
|
|
CN(c1cncc2c1cccc2)C(=O)Cc3cc(cc(c3)F)F |
−4.4
± 0.4
|
3.2
± 0.3
|
2444 |
MIC-UNK-ea4eb352-8
|
|
COC1(CCSc2c1cc(c(c2)Cl)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.4
± 0.2
|
3.2
± 0.2
|
2445 |
ALP-UNI-0676e700-30
|
|
CN1CCC(CC1)OCC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−4.4
± 0.3
|
3.2
± 0.2
|
2446 |
CHO-MSK-5891c1ff-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCOC5=O |
−4.4
± 0.4
|
3.2
± 0.3
|
2447 |
EDG-MED-90036822-48
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N(C)C |
−4.4
± 0.5
|
3.2
± 0.4
|
2448 |
EDJ-MED-6864a934-4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6nccn6ccn5 |
−4.4
± 0.4
|
3.2
± 0.3
|
2449 |
ED_-GRI-5b13fbe2-31
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCNC(=O)C5 |
−4.4
± 0.7
|
3.2
± 0.5
|
2450 |
KAD-UNI-8a629cb0-45
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6cc[nH]n6c5=O |
−4.4
± 0.3
|
3.2
± 0.2
|
2451 |
JOH-UNI-ee5ed7c8-11
|
|
c1ccc2c(c1)cnc(c2NC(=O)Cc3cccc(c3)Cl)CC(F)(F)F |
−4.4
± 0.3
|
3.2
± 0.2
|
2452 |
ALP-POS-a9ad2217-2
|
|
CN(C(c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3)C(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCCC5 |
−4.4
± 0.2
|
3.2
± 0.1
|
2453 |
BEN-DND-d1eb1f41-6
|
|
CN(C)Cc1ccc(cc1CC(=O)Nc2cncc3c2cccc3)Cl |
−4.3
± 0.2
|
3.2
± 0.2
|
2454 |
DAR-DIA-4987d2cd-2
|
|
c1ccc2c(c1)cncc2NC(=O)C3CN(Cc4c3cc(cc4)Cl)c5c(c(=O)c5=O)O |
−4.3
± 0.2
|
3.2
± 0.2
|
2455 |
MIC-UNK-54748b58-3
|
|
CNC(=O)CN1CC(c2cc(c(cc2S1(=O)=O)Cl)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.3
± 0.2
|
3.2
± 0.1
|
2456 |
ALP-UNI-0676e700-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(CC5)NC(=O)N |
−4.3
± 0.3
|
3.2
± 0.3
|
2457 |
PET-UNK-ac320b15-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H](c3cccc(c3)Cl)NC(=O)[C@@H]4CC[C@H](O4)C(=O)N5CCCC5 |
−4.3
± 0.5
|
3.2
± 0.4
|
2458 |
PET-UNK-1320d94d-30
|
|
CN([C@@H](c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3)C(=O)[C@@H]4CCC[C@@H](O4)C(=O)N5CCCC5 |
−4.3
± 0.2
|
3.1
± 0.2
|
2459 |
MIC-UNK-06e5f114-1
|
|
CS(=O)(=O)c1ccc(cc1)NCc2ccc(cc2CC(=O)Nc3cncc4c3cccc4)Cl |
−4.3
± 0.4
|
3.1
± 0.3
|
2460 |
PET-UNK-b78139fa-15
|
|
CO[C@]1(CS(=O)(=O)c2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cc(c(c4)F)F |
−4.3
± 0.3
|
3.1
± 0.2
|
2461 |
EDJ-MED-fcba3f31-11
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]5C[C@@H](CO5)CO |
−4.3
± 0.3
|
3.1
± 0.2
|
2462 |
PET-UNK-83d689b6-1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCn5ccnn5 |
−4.3
± 0.2
|
3.1
± 0.2
|
2463 |
PET-UNK-c65ea24c-1
|
|
CO[C@]1(CN(Cc2c1cc(cc2)Cl)S(=O)(=O)C)C(=O)Nc3cncc4c3ccc(c4)C#N |
−4.3
± 0.2
|
3.1
± 0.1
|
2464 |
MAT-POS-e69ad64a-3
|
|
C=CC(=O)N(c1cncc2c1cccc2)C(=O)Cc3ccc(c(c3)Cl)Cl |
−4.3
± 0.3
|
3.1
± 0.3
|
2465 |
EDJ-MED-d203f206-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CC56CC(C6)O |
−4.3
± 0.4
|
3.1
± 0.3
|
2466 |
LON-WEI-4d77710c-43
|
|
Cc1cc(c(cc1Cl)OC)NC(=O)Nc2cn(c(=O)c3c2cccc3)CC(C)C |
−4.3
± 0.1
|
3.1
± 0.1
|
2467 |
ALP-POS-5bb456a5-10
|
|
CCNC(=O)CN1CCN(CC1)C(=O)C[C@@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−4.3
± 0.2
|
3.1
± 0.2
|
2468 |
CHO-MSK-5891c1ff-4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCC[C@@H](C5)C(=O)N |
−4.3
± 0.6
|
3.1
± 0.5
|
2469 |
PET-UNK-1b92fa34-7
|
|
CO[C@]1(CS(=O)(=O)Cc2c1cc(c(c2)F)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.2
± 0.3
|
3.1
± 0.2
|
2470 |
EDJ-MED-d203f206-23
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CCCNC5=O |
−4.2
± 0.4
|
3.1
± 0.3
|
2471 |
UNK-UNK-2ede4078-96
|
|
Cc1cccc(c1C)N2CCN(CC2)C(=O)c3c[nH]c(=O)c4c3cccc4 |
−4.2
± 0.4
|
3.1
± 0.3
|
2472 |
EDJ-MED-96f6b92c-1
|
|
c1ccc2c(c1)cncc2N3CCCC(C3=O)(c4cccc(c4)Cl)O |
−4.2
± 0.4
|
3.1
± 0.3
|
2473 |
EDG-MED-90036822-80
|
|
CC(C#N)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.2
± 0.4
|
3.1
± 0.3
|
2474 |
JOH-UNI-6e27fddc-3
|
|
CO[C@]1(CCOc2c1cc(cc2)Cl)/C(=N\CC(F)F)/Nc3cncc4c3cccc4 |
−4.2
± 0.3
|
3.1
± 0.2
|
2475 |
BEN-DND-d1eb1f41-9
|
|
c1ccc2c(c1)cncc2N3CCN4CCc5ccc(cc5[C@@H]4C3=O)Cl |
−4.2
± 0.2
|
3.1
± 0.2
|
2476 |
ALP-UNI-76695c4f-7
|
|
CCN1CCN(CC1)C2CN(C2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−4.2
± 0.3
|
3.1
± 0.2
|
2477 |
ED_-GRI-5b13fbe2-53
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5c[nH]nc5 |
−4.2
± 0.5
|
3.1
± 0.4
|
2478 |
EDJ-MED-40433386-5
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H](C5CCC5)O |
−4.2
± 0.3
|
3.1
± 0.2
|
2479 |
RAL-THA-05e671eb-25
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3cc(cn4)Cl |
−4.2
± 0.5
|
3.1
± 0.3
|
2480 |
RAL-THA-e002e396-4
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCOc4c3cc(cc4)Cl)CS(=O)(=O)c5ccccn5 |
−4.2
± 0.2
|
3.0
± 0.1
|
2481 |
ALP-UNI-dbbfd3db-11
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5cc(c(=O)[nH]c5=O)C#N |
−4.2
± 0.3
|
3.0
± 0.2
|
2482 |
RYA-UNI-14580791-1
|
|
c1ccc2c(c1)cncc2NC(=O)N(c3ccc(cc3)Cl)c4ccc(cc4)Cl |
−4.2
± 0.3
|
3.0
± 0.2
|
2483 |
JIN-POS-6dc588a4-19
|
|
c1ccc2c(c1)c(c[nH]c2=O)NC(=O)Cc3cccc(c3)Cl |
−4.2
± 0.4
|
3.0
± 0.3
|
2484 |
ED_-GRI-5b13fbe2-46
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCC(CC5=O)C(=O)O |
−4.2
± 0.4
|
3.0
± 0.3
|
2485 |
VLA-MRT-a639d434-2
|
|
c1ccc2c(c1)cncc2N3C(=O)[C@@]4(CN(Cc5c4cc(cc5)Cl)CC(=O)N)NC3=O |
−4.1
± 0.3
|
3.0
± 0.2
|
2486 |
EDJ-MED-40433386-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@]5(CCSC5)O |
−4.1
± 0.3
|
3.0
± 0.2
|
2487 |
EDJ-MED-827e7cb4-3
|
|
CNC(=O)CN1CC(c2cc(ccc2C1=O)Cl)C(=O)Nc3cncc4c3cc(cc4)S(=O)(=O)C |
−4.1
± 0.4
|
3.0
± 0.3
|
2488 |
LON-WEI-5e7d1b3e-12
|
|
CCOC(=O)c1ccc(cc1)NC(=O)Nc2cn(c(=O)c3c2cccc3)C |
−4.1
± 0.2
|
3.0
± 0.1
|
2489 |
EDG-MED-90036822-71
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CN5CCNC5=O)(F)F |
−4.1
± 0.5
|
3.0
± 0.4
|
2490 |
ED_-GRI-5b13fbe2-52
|
|
CC(CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(c5cn(nn5)CC6CC6)N |
−4.1
± 0.4
|
3.0
± 0.3
|
2491 |
EDJ-MED-670ad2ee-5
|
|
c1cc2cncc(c2cc1F)NC(=O)[C@H]3CN(Cc4c3cc(cc4)Cl)S(=O)(=O)C5CC5 |
−4.1
± 0.5
|
3.0
± 0.4
|
2492 |
DAR-DIA-0587064e-23
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCNc4c3cc(cc4OCc5ccccc5Cl)Cl |
−4.1
± 0.2
|
3.0
± 0.1
|
2493 |
ALF-EVA-82cf4849-2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCNc4c3cc(c(c4)C5CC5)Cl |
−4.1
± 0.2
|
3.0
± 0.2
|
2494 |
PET-UNK-10339a1d-1
|
|
CN(C(c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3)C(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCCC5 |
−4.1
± 0.2
|
3.0
± 0.2
|
2495 |
PET-UNK-ac320b15-1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H](c3ccc(cc3)Cl)NC(=O)[C@@H]4CC[C@@H](O4)C(=O)N5CCCC5 |
−4.0
± 0.4
|
2.9
± 0.3
|
2496 |
EDJ-MED-611d11e7-9
|
|
COc1ccc2cncc(c2c1)NC(=O)[C@@H]3CCOc4c3cc(c(c4)F)Cl |
−4.0
± 0.4
|
2.9
± 0.3
|
2497 |
ED_-GRI-5b13fbe2-2
|
|
CC(CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NCc5cc(no5)C(=O)O |
−4.0
± 0.4
|
2.9
± 0.3
|
2498 |
ALF-EVA-82cf4849-7
|
|
c1cc2c(cc1C#N)cncc2NC(=O)[C@@H]3CCNc4c3cc(c(c4)Cl)Cl |
−4.0
± 0.2
|
2.9
± 0.2
|
2499 |
EDJ-MED-015fb6b4-1
|
|
CNC(=O)CN1CC(c2cc(ccc2C1=O)Cl)(C(=O)Nc3cncc4c3cccc4)OC |
−4.0
± 0.2
|
2.9
± 0.2
|
2500 |
EDJ-MED-d08626de-2
|
|
CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.0
± 0.4
|
2.9
± 0.3
|