| Rank | Compound | SMILES | ΔG / kcal M-1 | pIC50 | 
  
  
    | 701 | DAR-DIA-23e5a6a0-3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4OC5CC6(N5)COC6)Cl | −8.3
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 702 | EN300-247468_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC56COC6 | −8.3
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 703 | EN300-71405_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5ccn[nH]5 | −8.3
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 704 | EN300-1911992_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(C5CCOC5)O | −8.3
         ± 0.1 | 6.0
         ± 0.1 | 
  
  
    | 705 | EN300-39278_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCS(=O)(=O)CC5 | −8.3
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 706 | FRA-DIA-b66f7109-3 |   | c1ccc2c(c1)cncc2NC(=O)[C@H]3CCOc4c3cc(cc4Cl)OC5CC(=O)N5 | −8.3
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 707 | VLA-UCB-34f3ed0c-10 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCc5cc[nH]n5 | −8.3
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 708 | DAR-DIA-0d514e7d-6 |   | C[C@H]1COc2c(cc(cc2OC3CC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 | −8.3
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 709 | EN300-378343_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC=CC5CO | −8.3
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 710 | EN300-142333_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C6(C5)CC6)O | −8.3
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 711 | EN300-321703_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCOC5COC5 | −8.3
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 712 | PET-UNK-29afea89-1 |   | C#C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 | −8.25
         ± 0.10 | 6.01
         ± 0.07 | 
  
  
    | 713 | EN300-12440_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(=O)N(C5)C6CC6 | −8.3
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 714 | EN300-42270_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnsn5 | −8.3
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 715 | EN300-21258_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCO | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 716 | EN300-101796_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(c5)OCCO | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 717 | EN300-128277_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(=O)NCC(F)F | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 718 | EN300-107048_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CC5)CO | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 719 | EN300-7457159_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5cc(on5)C6(COC6)O | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 720 | EN300-98099_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(cs5)S(=O)(=O)N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 721 | EN300-99391_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC5CCOC5 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 722 | EN300-154944_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5OCCO5 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 723 | EN300-363154_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc([nH]c5=O)CC6CC6 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 724 | EN300-36158_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5COCCO5 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 725 | EN300-217107_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCC5C(=O)N | −8.2
         ± 0.1 | 6.0
         ± 0.1 | 
  
  
    | 726 | EN300-104029_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6C(C5)C(=O)NC6=O | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 727 | EN300-97300_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC5F | −8.2
         ± 0.1 | 6.00
         ± 0.08 | 
  
  
    | 728 | EN300-35843_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5[nH]c(=O)[nH]n5 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 729 | EN300-183001_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC#N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 730 | EN300-1071940_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5(CCCOC5)O | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 731 | EN300-123489_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(CO)(F)F | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 732 | EN300-107267_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC5CCCNC5=O | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 733 | EN300-51350_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCc6nncn6C5 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 734 | EN300-97938_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]([C@H](C5)O)O | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 735 | EN300-7434114_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)C(CCCO6)O | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 736 | EN300-1700143_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)c6ncon6 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 737 | EN300-1718836_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5nnc6n5CCOC6 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 738 | EN300-250120_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCS(=O)(=O)CC5 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 739 | EN300-107892_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cc(nn5)C6CC6 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 740 | EN300-1253178_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NC5CC5 | −8.2
         ± 0.1 | 5.98
         ± 0.10 | 
  
  
    | 741 | EN300-55498_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)COc5ccc(cc5)C(=O)N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 742 | EN300-233678_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C(C5)CO)O | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 743 | EN300-317082_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC5COC5 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 744 | EN300-1696043_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)C6COC6 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 745 | EN300-186943_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCOCC5=O | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 746 | EN300-222145_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CNC(=O)N5 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 747 | JOH-SUS-a69c159d-7 |   | c1cc2c(cc1F)c(c(nc2F)F)NC(=O)C3CCOc4c3cc(cc4)Cl | −8.20
         ± 0.09 | 5.97
         ± 0.06 | 
  
  
    | 748 | EN300-21813_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5c(=O)c6ccccc6nn5 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 749 | EN300-60330_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6C(C5)CCC6=O | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 750 | EN300-7431365_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6n(c5)CCCNC6=O | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 751 | EN300-227044_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CO)C#N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 752 | EN300-10895_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCCC#N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 753 | EN300-91315_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)Cc6ccccn6 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 754 | EN300-125143_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCCC(=O)N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 755 | EN300-246747_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5CC(=O)NC5 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 756 | EN300-44873_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCN5CCCS5(=O)=O | −8.2
         ± 0.5 | 6.0
         ± 0.4 | 
  
  
    | 757 | EN300-1717166_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC56CC(C6)O | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 758 | EN300-87536_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCCN5C(=O)N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 759 | EN300-861925_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC(CO)F | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 760 | EN300-367383_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@]56C[C@H]5COC6 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 761 | EN300-116234_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCCO5 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 762 | EN300-31562_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5c[nH]nc5 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 763 | EN300-817811_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)[nH]cn5 | −8.2
         ± 0.1 | 6.0
         ± 0.1 | 
  
  
    | 764 | EN300-256798_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCc6nnnn6CC5 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 765 | EN300-395654_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C6(C5)COC6)CO | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 766 | EN300-261859_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c(=O)[nH]sn5 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 767 | EN300-19762_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)CCO | −8.2
         ± 0.4 | 6.0
         ± 0.3 | 
  
  
    | 768 | EN300-96159_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5[nH]cnn5 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 769 | EN300-149013_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c([nH]nn5)Cl | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 770 | EN300-14006_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCS(=O)(=O)C5 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 771 | EN300-60837_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc6nncn6c5 | −8.2
         ± 0.2 | 6.0
         ± 0.1 | 
  
  
    | 772 | EN300-6503811_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H](Cc5cnc[nH]5)O | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 773 | EN300-6482296_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5COC6C5COC6 | −8.2
         ± 0.1 | 5.96
         ± 0.10 | 
  
  
    | 774 | EN300-2924757_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cc5)CC(=O)N | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 775 | EN300-243828_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnncc5O | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 776 | EN300-359842_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6ccnn6ccn5 | −8.2
         ± 0.2 | 6.0
         ± 0.2 | 
  
  
    | 777 | EN300-1589101_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5c[nH]nc5 | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 778 | EN300-196160_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)(c6[nH]nnn6)O | −8.2
         ± 0.3 | 6.0
         ± 0.2 | 
  
  
    | 779 | EN300-69107_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(=O)NCC5 | −8.2
         ± 0.2 | 5.9
         ± 0.1 | 
  
  
    | 780 | EN300-6238494_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)C5COCCO5 | −8.2
         ± 0.2 | 5.9
         ± 0.2 | 
  
  
    | 781 | EN300-92031_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5nc(no5)c6[nH]cnn6 | −8.2
         ± 0.3 | 5.9
         ± 0.2 | 
  
  
    | 782 | EN300-95094_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CSC5 | −8.2
         ± 0.2 | 5.9
         ± 0.1 | 
  
  
    | 783 | EN300-14437_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCS(=O)(=O)C5 | −8.2
         ± 0.2 | 5.9
         ± 0.1 | 
  
  
    | 784 | EN300-365017_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(on5)C6(COC6)O | −8.2
         ± 0.2 | 5.9
         ± 0.2 | 
  
  
    | 785 | EN300-1715993_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCn5ccnn5 | −8.2
         ± 0.2 | 5.9
         ± 0.2 | 
  
  
    | 786 | EN300-7457160_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5=NOC(C5)CC6(COC6)O | −8.2
         ± 0.2 | 5.9
         ± 0.2 | 
  
  
    | 787 | EN300-695831_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5nnc(s5)C(=O)N | −8.2
         ± 0.2 | 5.9
         ± 0.2 | 
  
  
    | 788 | DAR-DIA-0d514e7d-8 |   | C[C@H]1COc2ccc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)C#N | −8.15
         ± 0.09 | 5.94
         ± 0.06 | 
  
  
    | 789 | EN300-37102_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)C5CC5 | −8.1
         ± 0.3 | 5.9
         ± 0.2 | 
  
  
    | 790 | EN300-77092_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5OCCO5 | −8.1
         ± 0.3 | 5.9
         ± 0.2 | 
  
  
    | 791 | EN300-188377_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc6c5[nH]nn6 | −8.1
         ± 0.2 | 5.9
         ± 0.2 | 
  
  
    | 792 | EN300-97746_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)C5CCOCC5 | −8.1
         ± 0.3 | 5.9
         ± 0.2 | 
  
  
    | 793 | EN300-1725529_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCCO)C5COC5 | −8.1
         ± 0.4 | 5.9
         ± 0.3 | 
  
  
    | 794 | EN300-59478_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCC(=O)N | −8.1
         ± 0.3 | 5.9
         ± 0.2 | 
  
  
    | 795 | EN300-246992_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCC(=O)NC5 | −8.1
         ± 0.2 | 5.9
         ± 0.1 | 
  
  
    | 796 | EN300-83280_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5ccccn5 | −8.1
         ± 0.3 | 5.9
         ± 0.2 | 
  
  
    | 797 | EN300-1644723_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5C6C5COCC6 | −8.13
         ± 0.10 | 5.92
         ± 0.07 | 
  
  
    | 798 | EN300-10747_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CSCC5=O | −8.1
         ± 0.2 | 5.9
         ± 0.2 | 
  
  
    | 799 | EN300-13489_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCN(CC5)C(=O)N | −8.1
         ± 0.4 | 5.9
         ± 0.3 | 
  
  
    | 800 | EN300-1654606_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5C[C@@H]5F | −8.1
         ± 0.1 | 5.9
         ± 0.1 |