Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
701 |
DAR-DIA-23e5a6a0-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4OC5CC6(N5)COC6)Cl |
−8.3
± 0.3
|
6.0
± 0.2
|
702 |
EN300-247468_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC56COC6 |
−8.3
± 0.2
|
6.0
± 0.1
|
703 |
EN300-71405_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5ccn[nH]5 |
−8.3
± 0.2
|
6.0
± 0.2
|
704 |
EN300-1911992_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(C5CCOC5)O |
−8.3
± 0.1
|
6.0
± 0.1
|
705 |
EN300-39278_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCS(=O)(=O)CC5 |
−8.3
± 0.2
|
6.0
± 0.1
|
706 |
FRA-DIA-b66f7109-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3CCOc4c3cc(cc4Cl)OC5CC(=O)N5 |
−8.3
± 0.2
|
6.0
± 0.1
|
707 |
VLA-UCB-34f3ed0c-10
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCc5cc[nH]n5 |
−8.3
± 0.2
|
6.0
± 0.1
|
708 |
DAR-DIA-0d514e7d-6
|
|
C[C@H]1COc2c(cc(cc2OC3CC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−8.3
± 0.2
|
6.0
± 0.1
|
709 |
EN300-378343_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC=CC5CO |
−8.3
± 0.2
|
6.0
± 0.2
|
710 |
EN300-142333_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C6(C5)CC6)O |
−8.3
± 0.2
|
6.0
± 0.1
|
711 |
EN300-321703_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCOC5COC5 |
−8.3
± 0.2
|
6.0
± 0.2
|
712 |
PET-UNK-29afea89-1
|
|
C#C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−8.25
± 0.10
|
6.01
± 0.07
|
713 |
EN300-12440_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(=O)N(C5)C6CC6 |
−8.3
± 0.2
|
6.0
± 0.1
|
714 |
EN300-42270_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnsn5 |
−8.3
± 0.2
|
6.0
± 0.2
|
715 |
EN300-21258_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCO |
−8.2
± 0.2
|
6.0
± 0.1
|
716 |
EN300-101796_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(c5)OCCO |
−8.2
± 0.3
|
6.0
± 0.2
|
717 |
EN300-128277_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(=O)NCC(F)F |
−8.2
± 0.2
|
6.0
± 0.1
|
718 |
EN300-107048_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CC5)CO |
−8.2
± 0.3
|
6.0
± 0.2
|
719 |
EN300-7457159_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5cc(on5)C6(COC6)O |
−8.2
± 0.2
|
6.0
± 0.2
|
720 |
EN300-98099_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(cs5)S(=O)(=O)N |
−8.2
± 0.2
|
6.0
± 0.2
|
721 |
EN300-99391_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC5CCOC5 |
−8.2
± 0.2
|
6.0
± 0.1
|
722 |
EN300-154944_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5OCCO5 |
−8.2
± 0.3
|
6.0
± 0.2
|
723 |
EN300-363154_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc([nH]c5=O)CC6CC6 |
−8.2
± 0.3
|
6.0
± 0.2
|
724 |
EN300-36158_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5COCCO5 |
−8.2
± 0.2
|
6.0
± 0.1
|
725 |
EN300-217107_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCC5C(=O)N |
−8.2
± 0.1
|
6.0
± 0.1
|
726 |
EN300-104029_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6C(C5)C(=O)NC6=O |
−8.2
± 0.2
|
6.0
± 0.1
|
727 |
EN300-97300_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC5F |
−8.2
± 0.1
|
6.00
± 0.08
|
728 |
EN300-35843_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5[nH]c(=O)[nH]n5 |
−8.2
± 0.2
|
6.0
± 0.2
|
729 |
EN300-183001_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC#N |
−8.2
± 0.2
|
6.0
± 0.2
|
730 |
EN300-1071940_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5(CCCOC5)O |
−8.2
± 0.2
|
6.0
± 0.2
|
731 |
EN300-123489_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(CO)(F)F |
−8.2
± 0.3
|
6.0
± 0.2
|
732 |
EN300-107267_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC5CCCNC5=O |
−8.2
± 0.2
|
6.0
± 0.1
|
733 |
EN300-51350_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCc6nncn6C5 |
−8.2
± 0.2
|
6.0
± 0.2
|
734 |
EN300-97938_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]([C@H](C5)O)O |
−8.2
± 0.2
|
6.0
± 0.2
|
735 |
EN300-7434114_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)C(CCCO6)O |
−8.2
± 0.2
|
6.0
± 0.1
|
736 |
EN300-1700143_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)c6ncon6 |
−8.2
± 0.2
|
6.0
± 0.1
|
737 |
EN300-1718836_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5nnc6n5CCOC6 |
−8.2
± 0.2
|
6.0
± 0.2
|
738 |
EN300-250120_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCS(=O)(=O)CC5 |
−8.2
± 0.3
|
6.0
± 0.2
|
739 |
EN300-107892_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cc(nn5)C6CC6 |
−8.2
± 0.3
|
6.0
± 0.2
|
740 |
EN300-1253178_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NC5CC5 |
−8.2
± 0.1
|
5.98
± 0.10
|
741 |
EN300-55498_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)COc5ccc(cc5)C(=O)N |
−8.2
± 0.2
|
6.0
± 0.2
|
742 |
EN300-233678_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C(C5)CO)O |
−8.2
± 0.2
|
6.0
± 0.1
|
743 |
EN300-317082_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC5COC5 |
−8.2
± 0.2
|
6.0
± 0.1
|
744 |
EN300-1696043_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)C6COC6 |
−8.2
± 0.2
|
6.0
± 0.1
|
745 |
EN300-186943_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCOCC5=O |
−8.2
± 0.3
|
6.0
± 0.2
|
746 |
EN300-222145_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CNC(=O)N5 |
−8.2
± 0.2
|
6.0
± 0.2
|
747 |
JOH-SUS-a69c159d-7
|
|
c1cc2c(cc1F)c(c(nc2F)F)NC(=O)C3CCOc4c3cc(cc4)Cl |
−8.20
± 0.09
|
5.97
± 0.06
|
748 |
EN300-21813_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5c(=O)c6ccccc6nn5 |
−8.2
± 0.3
|
6.0
± 0.2
|
749 |
EN300-60330_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6C(C5)CCC6=O |
−8.2
± 0.2
|
6.0
± 0.1
|
750 |
EN300-7431365_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6n(c5)CCCNC6=O |
−8.2
± 0.2
|
6.0
± 0.2
|
751 |
EN300-227044_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CO)C#N |
−8.2
± 0.2
|
6.0
± 0.2
|
752 |
EN300-10895_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCCC#N |
−8.2
± 0.2
|
6.0
± 0.2
|
753 |
EN300-91315_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)Cc6ccccn6 |
−8.2
± 0.2
|
6.0
± 0.2
|
754 |
EN300-125143_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCCC(=O)N |
−8.2
± 0.2
|
6.0
± 0.2
|
755 |
EN300-246747_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5CC(=O)NC5 |
−8.2
± 0.2
|
6.0
± 0.1
|
756 |
EN300-44873_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCN5CCCS5(=O)=O |
−8.2
± 0.5
|
6.0
± 0.4
|
757 |
EN300-1717166_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC56CC(C6)O |
−8.2
± 0.2
|
6.0
± 0.1
|
758 |
EN300-87536_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCCN5C(=O)N |
−8.2
± 0.2
|
6.0
± 0.2
|
759 |
EN300-861925_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC(CO)F |
−8.2
± 0.2
|
6.0
± 0.1
|
760 |
EN300-367383_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@]56C[C@H]5COC6 |
−8.2
± 0.2
|
6.0
± 0.2
|
761 |
EN300-116234_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCCO5 |
−8.2
± 0.2
|
6.0
± 0.2
|
762 |
EN300-31562_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5c[nH]nc5 |
−8.2
± 0.2
|
6.0
± 0.2
|
763 |
EN300-817811_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)[nH]cn5 |
−8.2
± 0.1
|
6.0
± 0.1
|
764 |
EN300-256798_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCc6nnnn6CC5 |
−8.2
± 0.2
|
6.0
± 0.1
|
765 |
EN300-395654_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C6(C5)COC6)CO |
−8.2
± 0.2
|
6.0
± 0.2
|
766 |
EN300-261859_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c(=O)[nH]sn5 |
−8.2
± 0.2
|
6.0
± 0.2
|
767 |
EN300-19762_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)CCO |
−8.2
± 0.4
|
6.0
± 0.3
|
768 |
EN300-96159_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5[nH]cnn5 |
−8.2
± 0.3
|
6.0
± 0.2
|
769 |
EN300-149013_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c([nH]nn5)Cl |
−8.2
± 0.2
|
6.0
± 0.2
|
770 |
EN300-14006_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCS(=O)(=O)C5 |
−8.2
± 0.3
|
6.0
± 0.2
|
771 |
EN300-60837_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc6nncn6c5 |
−8.2
± 0.2
|
6.0
± 0.1
|
772 |
EN300-6503811_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H](Cc5cnc[nH]5)O |
−8.2
± 0.2
|
6.0
± 0.2
|
773 |
EN300-6482296_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5COC6C5COC6 |
−8.2
± 0.1
|
5.96
± 0.10
|
774 |
EN300-2924757_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cc5)CC(=O)N |
−8.2
± 0.2
|
6.0
± 0.2
|
775 |
EN300-243828_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnncc5O |
−8.2
± 0.2
|
6.0
± 0.2
|
776 |
EN300-359842_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6ccnn6ccn5 |
−8.2
± 0.2
|
6.0
± 0.2
|
777 |
EN300-1589101_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5c[nH]nc5 |
−8.2
± 0.3
|
6.0
± 0.2
|
778 |
EN300-196160_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)(c6[nH]nnn6)O |
−8.2
± 0.3
|
6.0
± 0.2
|
779 |
EN300-69107_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(=O)NCC5 |
−8.2
± 0.2
|
5.9
± 0.1
|
780 |
EN300-6238494_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)C5COCCO5 |
−8.2
± 0.2
|
5.9
± 0.2
|
781 |
EN300-92031_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5nc(no5)c6[nH]cnn6 |
−8.2
± 0.3
|
5.9
± 0.2
|
782 |
EN300-95094_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CSC5 |
−8.2
± 0.2
|
5.9
± 0.1
|
783 |
EN300-14437_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCS(=O)(=O)C5 |
−8.2
± 0.2
|
5.9
± 0.1
|
784 |
EN300-365017_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(on5)C6(COC6)O |
−8.2
± 0.2
|
5.9
± 0.2
|
785 |
EN300-1715993_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCn5ccnn5 |
−8.2
± 0.2
|
5.9
± 0.2
|
786 |
EN300-7457160_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5=NOC(C5)CC6(COC6)O |
−8.2
± 0.2
|
5.9
± 0.2
|
787 |
EN300-695831_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5nnc(s5)C(=O)N |
−8.2
± 0.2
|
5.9
± 0.2
|
788 |
DAR-DIA-0d514e7d-8
|
|
C[C@H]1COc2ccc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)C#N |
−8.15
± 0.09
|
5.94
± 0.06
|
789 |
EN300-37102_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)C5CC5 |
−8.1
± 0.3
|
5.9
± 0.2
|
790 |
EN300-77092_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5OCCO5 |
−8.1
± 0.3
|
5.9
± 0.2
|
791 |
EN300-188377_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc6c5[nH]nn6 |
−8.1
± 0.2
|
5.9
± 0.2
|
792 |
EN300-97746_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)C5CCOCC5 |
−8.1
± 0.3
|
5.9
± 0.2
|
793 |
EN300-1725529_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCCO)C5COC5 |
−8.1
± 0.4
|
5.9
± 0.3
|
794 |
EN300-59478_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCC(=O)N |
−8.1
± 0.3
|
5.9
± 0.2
|
795 |
EN300-246992_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCC(=O)NC5 |
−8.1
± 0.2
|
5.9
± 0.1
|
796 |
EN300-83280_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5ccccn5 |
−8.1
± 0.3
|
5.9
± 0.2
|
797 |
EN300-1644723_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5C6C5COCC6 |
−8.13
± 0.10
|
5.92
± 0.07
|
798 |
EN300-10747_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CSCC5=O |
−8.1
± 0.2
|
5.9
± 0.2
|
799 |
EN300-13489_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCN(CC5)C(=O)N |
−8.1
± 0.4
|
5.9
± 0.3
|
800 |
EN300-1654606_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5C[C@@H]5F |
−8.1
± 0.1
|
5.9
± 0.1
|