Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
501 |
EN300-246747_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CC(=O)NC5 |
−8.6
± 0.2
|
6.2
± 0.1
|
502 |
EN300-19507_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(F)F |
−8.6
± 0.2
|
6.2
± 0.1
|
503 |
EN300-245265_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCn5cnc(n5)C#N |
−8.6
± 0.3
|
6.2
± 0.2
|
504 |
EN300-1662365_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCc6ncnn6C5 |
−8.6
± 0.1
|
6.2
± 0.1
|
505 |
EN300-77092_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5OCCO5 |
−8.6
± 0.2
|
6.2
± 0.2
|
506 |
EN300-118045_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc([nH]c5=O)C6CC6 |
−8.6
± 0.3
|
6.2
± 0.2
|
507 |
EN300-21258_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCO |
−8.6
± 0.2
|
6.2
± 0.1
|
508 |
EN300-153245_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H](C[C@H]5CO)O |
−8.5
± 0.3
|
6.2
± 0.2
|
509 |
EN300-6238494_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)C5COCCO5 |
−8.5
± 0.2
|
6.2
± 0.1
|
510 |
EN300-306316_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5[nH]cnn5 |
−8.5
± 0.2
|
6.2
± 0.1
|
511 |
EN300-5253939_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5COC(=O)O5 |
−8.5
± 0.2
|
6.2
± 0.1
|
512 |
EN300-214849_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5nnc6n5nc[nH]6 |
−8.5
± 0.2
|
6.2
± 0.1
|
513 |
EN300-7445396_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5Cc6c[nH]cc6S5(=O)=O |
−8.5
± 0.3
|
6.2
± 0.2
|
514 |
EN300-1664603_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5ccn[nH]5 |
−8.5
± 0.2
|
6.2
± 0.2
|
515 |
EN300-222620_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cc(cnc5)O |
−8.5
± 0.2
|
6.2
± 0.2
|
516 |
EN300-1932780_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C(F)F)O |
−8.5
± 0.2
|
6.2
± 0.1
|
517 |
EN300-314088_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]([C@@H](C5)CO)CO |
−8.5
± 0.3
|
6.2
± 0.2
|
518 |
EN300-120820_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cn[nH]c5=O |
−8.5
± 0.2
|
6.2
± 0.2
|
519 |
EN300-872798_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5c(nnn5)C6CC6 |
−8.5
± 0.3
|
6.2
± 0.2
|
520 |
EN300-172179_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCOC5=O |
−8.5
± 0.2
|
6.2
± 0.2
|
521 |
EN300-25702_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)O |
−8.5
± 0.2
|
6.2
± 0.2
|
522 |
EN300-113234_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(=O)OC5 |
−8.5
± 0.2
|
6.2
± 0.1
|
523 |
EN300-182579_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CN(C5)CC(F)F |
−8.5
± 0.2
|
6.2
± 0.2
|
524 |
EN300-97300_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC5F |
−8.5
± 0.2
|
6.2
± 0.1
|
525 |
EN300-121144_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5ccccc5C(=O)N |
−8.5
± 0.2
|
6.2
± 0.2
|
526 |
EN300-6758891_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6COCCN6C(=O)C5 |
−8.5
± 0.2
|
6.2
± 0.2
|
527 |
EN300-113234_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC(=O)OC5 |
−8.5
± 0.2
|
6.2
± 0.1
|
528 |
EN300-47606_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCC5CCS(=O)(=O)C5 |
−8.5
± 0.3
|
6.2
± 0.2
|
529 |
EN300-101197_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5[nH]cnn5 |
−8.5
± 0.2
|
6.2
± 0.2
|
530 |
EN300-101197_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5[nH]cnn5 |
−8.5
± 0.3
|
6.2
± 0.2
|
531 |
EN300-10170_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CO)NC(=O)N |
−8.5
± 0.2
|
6.2
± 0.2
|
532 |
EN300-7385389_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cnc(n5)C(F)(F)F |
−8.5
± 0.3
|
6.2
± 0.2
|
533 |
EN300-01527_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCC5CCCO5 |
−8.5
± 0.2
|
6.2
± 0.2
|
534 |
EN300-33513_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CSCC(=O)N |
−8.5
± 0.3
|
6.2
± 0.2
|
535 |
EN300-332606_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCC(=O)O5 |
−8.5
± 0.2
|
6.2
± 0.1
|
536 |
EN300-222357_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCc5c[nH]nn5 |
−8.5
± 0.2
|
6.2
± 0.1
|
537 |
EN300-34636_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cccc(=O)[nH]5 |
−8.5
± 0.2
|
6.2
± 0.2
|
538 |
EN300-6494158_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5CC(CO5)CO |
−8.5
± 0.1
|
6.20
± 0.10
|
539 |
EN300-114134_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCCS5(=O)=O |
−8.5
± 0.2
|
6.2
± 0.2
|
540 |
EN300-250593_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CC(=O)N5 |
−8.5
± 0.2
|
6.2
± 0.2
|
541 |
EN300-73772_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5[nH]c(=O)[nH]n5 |
−8.5
± 0.2
|
6.2
± 0.2
|
542 |
EN300-341337_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C56CCOC5CCOC6 |
−8.5
± 0.2
|
6.2
± 0.2
|
543 |
EN300-52009_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCC5)O |
−8.5
± 0.2
|
6.2
± 0.2
|
544 |
EN300-21258_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCO |
−8.5
± 0.2
|
6.2
± 0.1
|
545 |
EN300-1600517_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(CO)F |
−8.5
± 0.2
|
6.2
± 0.2
|
546 |
EN300-185751_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cncnc5 |
−8.5
± 0.2
|
6.2
± 0.1
|
547 |
EN300-140751_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnnn5CC6CC6 |
−8.5
± 0.3
|
6.2
± 0.2
|
548 |
EN300-244403_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CNC(=O)O5 |
−8.5
± 0.2
|
6.2
± 0.1
|
549 |
EN300-73772_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5[nH]c(=O)[nH]n5 |
−8.5
± 0.2
|
6.2
± 0.1
|
550 |
EN300-102347_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5(COC5)CO |
−8.5
± 0.2
|
6.2
± 0.2
|
551 |
EN300-128715_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC(=O)NCC(F)(F)F |
−8.5
± 0.2
|
6.2
± 0.2
|
552 |
EN300-170463_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCOC5 |
−8.5
± 0.2
|
6.2
± 0.2
|
553 |
EN300-145616_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5cnc[nH]5 |
−8.5
± 0.3
|
6.2
± 0.2
|
554 |
EN300-43939_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)CC(F)(F)F |
−8.5
± 0.2
|
6.2
± 0.2
|
555 |
EN300-315792_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COCC(F)F |
−8.5
± 0.2
|
6.2
± 0.2
|
556 |
EN300-109535_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CC(=O)OC5 |
−8.5
± 0.2
|
6.2
± 0.1
|
557 |
EN300-2690393_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(cnc5)n6cnnn6 |
−8.5
± 0.3
|
6.2
± 0.2
|
558 |
EN300-50514_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)COc5ccc(cc5)CC(=O)N |
−8.5
± 0.2
|
6.2
± 0.2
|
559 |
EN300-189563_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCC5CS(=O)(=O)C5 |
−8.5
± 0.2
|
6.2
± 0.2
|
560 |
EN300-6744029_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ccsc5n6cnnn6 |
−8.5
± 0.3
|
6.2
± 0.2
|
561 |
EN300-6494859_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(OC5)Cn6cccn6 |
−8.5
± 0.2
|
6.2
± 0.1
|
562 |
EN300-179091_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC(F)F |
−8.5
± 0.2
|
6.2
± 0.1
|
563 |
EN300-178829_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC(=O)NCC5CC5 |
−8.5
± 0.3
|
6.2
± 0.2
|
564 |
EN300-120569_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)CCCC#N |
−8.5
± 0.2
|
6.2
± 0.2
|
565 |
EN300-05620_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCNC(=O)N |
−8.5
± 0.2
|
6.2
± 0.2
|
566 |
EN300-1265948_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCS(=O)(=O)CC5 |
−8.5
± 0.3
|
6.2
± 0.2
|
567 |
EN300-1706036_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5C(=O)NCCO5 |
−8.5
± 0.2
|
6.2
± 0.2
|
568 |
EN300-254121_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(c5cnc[nH]5)O |
−8.5
± 0.2
|
6.2
± 0.2
|
569 |
EN300-31998_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c[nH]nn5 |
−8.5
± 0.2
|
6.2
± 0.1
|
570 |
EN300-90142_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCC(C5)C(=O)N |
−8.5
± 0.2
|
6.2
± 0.1
|
571 |
EN300-1722017_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CC5)n6nccn6 |
−8.5
± 0.2
|
6.2
± 0.1
|
572 |
EN300-22880_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCCC(C5)C(=O)N |
−8.5
± 0.3
|
6.2
± 0.2
|
573 |
EN300-370967_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCOC5=O |
−8.5
± 0.2
|
6.2
± 0.1
|
574 |
EN300-08259_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCCCN5CCCC5=O |
−8.5
± 0.3
|
6.2
± 0.2
|
575 |
EN300-135182_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)n6c([nH]5)ncn6 |
−8.5
± 0.2
|
6.2
± 0.2
|
576 |
EN300-203293_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5CNC(=O)O5 |
−8.5
± 0.3
|
6.2
± 0.2
|
577 |
EN300-107823_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5ncnn5 |
−8.4
± 0.3
|
6.2
± 0.2
|
578 |
EN300-261365_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CS(=O)(=O)C5 |
−8.4
± 0.2
|
6.2
± 0.2
|
579 |
EN300-7385329_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5Cc6nccn6C5 |
−8.4
± 0.2
|
6.1
± 0.1
|
580 |
EN300-221518_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCCO |
−8.4
± 0.1
|
6.15
± 0.08
|
581 |
EN300-07752_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(CC5C(=O)N)O |
−8.4
± 0.2
|
6.1
± 0.1
|
582 |
EN300-6491117_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cnco5 |
−8.4
± 0.2
|
6.1
± 0.2
|
583 |
EN300-94945_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCNC5=O |
−8.4
± 0.2
|
6.1
± 0.1
|
584 |
EN300-310888_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5nnc6n5CCOCC6 |
−8.4
± 0.2
|
6.1
± 0.2
|
585 |
EN300-222357_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCc5c[nH]nn5 |
−8.4
± 0.2
|
6.1
± 0.1
|
586 |
EN300-317555_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5=NCCO5 |
−8.4
± 0.2
|
6.1
± 0.1
|
587 |
EN300-7430501_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCn6c(cnn6)C5 |
−8.4
± 0.1
|
6.1
± 0.1
|
588 |
EN300-214800_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCNC5=O |
−8.4
± 0.3
|
6.1
± 0.2
|
589 |
EN300-10170_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(CO)NC(=O)N |
−8.4
± 0.3
|
6.1
± 0.2
|
590 |
EN300-107990_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5cccnc5 |
−8.4
± 0.2
|
6.1
± 0.2
|
591 |
EN300-6732784_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c(c(n[nH]6)CO)C5 |
−8.4
± 0.2
|
6.1
± 0.2
|
592 |
EN300-1911992_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(C5CCOC5)O |
−8.4
± 0.2
|
6.1
± 0.1
|
593 |
EN300-19242_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CO |
−8.4
± 0.2
|
6.1
± 0.1
|
594 |
EN300-1608590_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5nc(on5)N6CCOCC6 |
−8.4
± 0.3
|
6.1
± 0.2
|
595 |
EN300-82037_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5ccon5 |
−8.4
± 0.2
|
6.1
± 0.2
|
596 |
EN300-13252_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCCCNC(=O)N |
−8.4
± 0.3
|
6.1
± 0.2
|
597 |
EN300-249804_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCOC(=O)N5 |
−8.4
± 0.2
|
6.1
± 0.2
|
598 |
EN300-237561_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5c(=O)cccn5 |
−8.4
± 0.3
|
6.1
± 0.2
|
599 |
EN300-6494158_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CC(CO5)CO |
−8.4
± 0.2
|
6.1
± 0.1
|
600 |
EN300-7121836_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn[nH]c5F |
−8.4
± 0.2
|
6.1
± 0.1
|