| Rank | Compound | SMILES | ΔG / kcal M-1 | pIC50 | 
  
  
    | 501 | EN300-246747_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CC(=O)NC5 | −8.6
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 502 | EN300-19507_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(F)F | −8.6
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 503 | EN300-245265_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCn5cnc(n5)C#N | −8.6
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 504 | EN300-1662365_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCc6ncnn6C5 | −8.6
         ± 0.1 | 6.2
         ± 0.1 | 
  
  
    | 505 | EN300-77092_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5OCCO5 | −8.6
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 506 | EN300-118045_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc([nH]c5=O)C6CC6 | −8.6
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 507 | EN300-21258_4 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCO | −8.6
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 508 | EN300-153245_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H](C[C@H]5CO)O | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 509 | EN300-6238494_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)C5COCCO5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 510 | EN300-306316_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5[nH]cnn5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 511 | EN300-5253939_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5COC(=O)O5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 512 | EN300-214849_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5nnc6n5nc[nH]6 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 513 | EN300-7445396_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5Cc6c[nH]cc6S5(=O)=O | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 514 | EN300-1664603_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5ccn[nH]5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 515 | EN300-222620_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cc(cnc5)O | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 516 | EN300-1932780_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C(F)F)O | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 517 | EN300-314088_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]([C@@H](C5)CO)CO | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 518 | EN300-120820_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cn[nH]c5=O | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 519 | EN300-872798_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5c(nnn5)C6CC6 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 520 | EN300-172179_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCOC5=O | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 521 | EN300-25702_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)O | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 522 | EN300-113234_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(=O)OC5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 523 | EN300-182579_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CN(C5)CC(F)F | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 524 | EN300-97300_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC5F | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 525 | EN300-121144_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5ccccc5C(=O)N | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 526 | EN300-6758891_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6COCCN6C(=O)C5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 527 | EN300-113234_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC(=O)OC5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 528 | EN300-47606_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCC5CCS(=O)(=O)C5 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 529 | EN300-101197_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5[nH]cnn5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 530 | EN300-101197_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5[nH]cnn5 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 531 | EN300-10170_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CO)NC(=O)N | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 532 | EN300-7385389_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cnc(n5)C(F)(F)F | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 533 | EN300-01527_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCC5CCCO5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 534 | EN300-33513_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CSCC(=O)N | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 535 | EN300-332606_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCC(=O)O5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 536 | EN300-222357_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCc5c[nH]nn5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 537 | EN300-34636_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cccc(=O)[nH]5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 538 | EN300-6494158_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5CC(CO5)CO | −8.5
         ± 0.1 | 6.20
         ± 0.10 | 
  
  
    | 539 | EN300-114134_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCCS5(=O)=O | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 540 | EN300-250593_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CC(=O)N5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 541 | EN300-73772_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5[nH]c(=O)[nH]n5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 542 | EN300-341337_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C56CCOC5CCOC6 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 543 | EN300-52009_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCC5)O | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 544 | EN300-21258_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCO | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 545 | EN300-1600517_4 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(CO)F | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 546 | EN300-185751_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cncnc5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 547 | EN300-140751_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnnn5CC6CC6 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 548 | EN300-244403_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CNC(=O)O5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 549 | EN300-73772_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5[nH]c(=O)[nH]n5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 550 | EN300-102347_4 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5(COC5)CO | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 551 | EN300-128715_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC(=O)NCC(F)(F)F | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 552 | EN300-170463_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCOC5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 553 | EN300-145616_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5cnc[nH]5 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 554 | EN300-43939_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)CC(F)(F)F | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 555 | EN300-315792_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COCC(F)F | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 556 | EN300-109535_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CC(=O)OC5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 557 | EN300-2690393_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(cnc5)n6cnnn6 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 558 | EN300-50514_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)COc5ccc(cc5)CC(=O)N | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 559 | EN300-189563_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCC5CS(=O)(=O)C5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 560 | EN300-6744029_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ccsc5n6cnnn6 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 561 | EN300-6494859_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(OC5)Cn6cccn6 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 562 | EN300-179091_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC(F)F | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 563 | EN300-178829_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC(=O)NCC5CC5 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 564 | EN300-120569_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)CCCC#N | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 565 | EN300-05620_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCNC(=O)N | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 566 | EN300-1265948_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCS(=O)(=O)CC5 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 567 | EN300-1706036_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5C(=O)NCCO5 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 568 | EN300-254121_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(c5cnc[nH]5)O | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 569 | EN300-31998_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c[nH]nn5 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 570 | EN300-90142_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCC(C5)C(=O)N | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 571 | EN300-1722017_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CC5)n6nccn6 | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 572 | EN300-22880_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCCC(C5)C(=O)N | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 573 | EN300-370967_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCOC5=O | −8.5
         ± 0.2 | 6.2
         ± 0.1 | 
  
  
    | 574 | EN300-08259_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCCCN5CCCC5=O | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 575 | EN300-135182_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)n6c([nH]5)ncn6 | −8.5
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 576 | EN300-203293_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5CNC(=O)O5 | −8.5
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 577 | EN300-107823_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5ncnn5 | −8.4
         ± 0.3 | 6.2
         ± 0.2 | 
  
  
    | 578 | EN300-261365_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CS(=O)(=O)C5 | −8.4
         ± 0.2 | 6.2
         ± 0.2 | 
  
  
    | 579 | EN300-7385329_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5Cc6nccn6C5 | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 580 | EN300-221518_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCCO | −8.4
         ± 0.1 | 6.15
         ± 0.08 | 
  
  
    | 581 | EN300-07752_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(CC5C(=O)N)O | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 582 | EN300-6491117_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cnco5 | −8.4
         ± 0.2 | 6.1
         ± 0.2 | 
  
  
    | 583 | EN300-94945_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCNC5=O | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 584 | EN300-310888_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5nnc6n5CCOCC6 | −8.4
         ± 0.2 | 6.1
         ± 0.2 | 
  
  
    | 585 | EN300-222357_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCc5c[nH]nn5 | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 586 | EN300-317555_4 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5=NCCO5 | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 587 | EN300-7430501_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCn6c(cnn6)C5 | −8.4
         ± 0.1 | 6.1
         ± 0.1 | 
  
  
    | 588 | EN300-214800_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCNC5=O | −8.4
         ± 0.3 | 6.1
         ± 0.2 | 
  
  
    | 589 | EN300-10170_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(CO)NC(=O)N | −8.4
         ± 0.3 | 6.1
         ± 0.2 | 
  
  
    | 590 | EN300-107990_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5cccnc5 | −8.4
         ± 0.2 | 6.1
         ± 0.2 | 
  
  
    | 591 | EN300-6732784_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c(c(n[nH]6)CO)C5 | −8.4
         ± 0.2 | 6.1
         ± 0.2 | 
  
  
    | 592 | EN300-1911992_2 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(C5CCOC5)O | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 593 | EN300-19242_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CO | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 594 | EN300-1608590_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5nc(on5)N6CCOCC6 | −8.4
         ± 0.3 | 6.1
         ± 0.2 | 
  
  
    | 595 | EN300-82037_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5ccon5 | −8.4
         ± 0.2 | 6.1
         ± 0.2 | 
  
  
    | 596 | EN300-13252_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCCCNC(=O)N | −8.4
         ± 0.3 | 6.1
         ± 0.2 | 
  
  
    | 597 | EN300-249804_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCOC(=O)N5 | −8.4
         ± 0.2 | 6.1
         ± 0.2 | 
  
  
    | 598 | EN300-237561_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5c(=O)cccn5 | −8.4
         ± 0.3 | 6.1
         ± 0.2 | 
  
  
    | 599 | EN300-6494158_3 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CC(CO5)CO | −8.4
         ± 0.2 | 6.1
         ± 0.1 | 
  
  
    | 600 | EN300-7121836_1 |   | c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn[nH]c5F | −8.4
         ± 0.2 | 6.1
         ± 0.1 |