Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
4001 |
EN300-1233032_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(Cn5cccn5)O |
−4.0
± 0.3
|
2.9
± 0.2
|
4002 |
EN300-80481_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(C5CCOCC5)O |
−3.9
± 0.2
|
2.9
± 0.2
|
4003 |
EN300-41663_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5COCCO5 |
−3.9
± 0.2
|
2.9
± 0.1
|
4004 |
EN300-61086_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(C5CC5)C6CC(=O)NC6=O |
−3.9
± 0.3
|
2.9
± 0.2
|
4005 |
EN300-126866_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)N5CCOCC5 |
−3.9
± 0.4
|
2.9
± 0.3
|
4006 |
EN300-309457_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CN(C5)C6CCOC6 |
−3.9
± 0.2
|
2.9
± 0.2
|
4007 |
EN300-205518_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCS(=O)(=O)CC5)O |
−3.9
± 0.3
|
2.9
± 0.2
|
4008 |
EN300-114312_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CCC5 |
−3.9
± 0.4
|
2.9
± 0.3
|
4009 |
EN300-316193_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]6COC(=O)[C@H]6C5 |
−3.9
± 0.3
|
2.8
± 0.2
|
4010 |
EN300-7427798_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC6CS(=O)(=O)CC6C5 |
−3.9
± 0.3
|
2.8
± 0.2
|
4011 |
EN300-36522_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CNC(=O)C5CC5 |
−3.9
± 0.3
|
2.8
± 0.2
|
4012 |
EN300-77408_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CN(CCO5)C6CC6 |
−3.9
± 0.1
|
2.8
± 0.1
|
4013 |
EN300-7499295_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CCCO)CO |
−3.9
± 0.2
|
2.8
± 0.1
|
4014 |
EN300-817811_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(=O)[nH]cn5 |
−3.9
± 0.2
|
2.8
± 0.1
|
4015 |
EN300-125100_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cccc(=O)[nH]5 |
−3.9
± 0.3
|
2.8
± 0.2
|
4016 |
EN300-7356782_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNC(=O)CC5C(=O)N |
−3.9
± 0.2
|
2.8
± 0.2
|
4017 |
EN300-144970_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H](C5)CO |
−3.9
± 0.2
|
2.8
± 0.2
|
4018 |
EN300-78135_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(=O)NC5CC5 |
−3.9
± 0.2
|
2.8
± 0.2
|
4019 |
EN300-261178_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]c(=O)ccn5 |
−3.9
± 0.3
|
2.8
± 0.2
|
4020 |
EN300-226334_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCCN(C5)CCCO |
−3.9
± 0.4
|
2.8
± 0.3
|
4021 |
EN300-260475_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)N5CCCO5 |
−3.8
± 0.3
|
2.8
± 0.2
|
4022 |
EN300-142130_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H](CO)C(F)(F)F |
−3.8
± 0.4
|
2.8
± 0.3
|
4023 |
EN300-28262_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccnc6n5ncn6 |
−3.8
± 0.3
|
2.8
± 0.2
|
4024 |
EN300-6487134_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC56CC(C5)C(=O)NC6 |
−3.8
± 0.3
|
2.8
± 0.2
|
4025 |
EN300-42007_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCN(CC5)CC(=O)N |
−3.8
± 0.3
|
2.8
± 0.2
|
4026 |
EN300-114540_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CN6CCN5CC6 |
−3.8
± 0.3
|
2.8
± 0.2
|
4027 |
EN300-701259_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cnc6n5CCOC6 |
−3.8
± 0.5
|
2.8
± 0.3
|
4028 |
EN300-1091489_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5C[C@H]6[C@@H]5CC(C6)C(=O)N |
−3.8
± 0.3
|
2.8
± 0.2
|
4029 |
EN300-05620_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCNC(=O)N |
−3.8
± 0.3
|
2.8
± 0.2
|
4030 |
EN300-6489696_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(Cc6ccn[nH]6)O |
−3.8
± 0.4
|
2.8
± 0.3
|
4031 |
EN300-268196_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)N6CCOCC6 |
−3.8
± 0.3
|
2.8
± 0.2
|
4032 |
EN300-11934_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCCC5=O |
−3.8
± 0.3
|
2.8
± 0.2
|
4033 |
EN300-212797_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CN5CCCC5)CO |
−3.8
± 0.4
|
2.8
± 0.3
|
4034 |
EN300-208465_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CN6CCC5CC6)O |
−3.8
± 0.3
|
2.8
± 0.2
|
4035 |
EN300-321161_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCN5CCOCC5 |
−3.8
± 0.2
|
2.7
± 0.2
|
4036 |
MAK-UNK-83e0a0b4-4
|
|
CCCCc1ccc2c(c1)C(CCO2)C(=O)N(CCNC3CNC3)c4cncc5c4cccc5 |
−3.8
± 0.4
|
2.7
± 0.3
|
4037 |
EN300-53433_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCNC(=O)c5cnccn5 |
−3.7
± 0.3
|
2.7
± 0.2
|
4038 |
EN300-754584_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5CS(=O)(=O)CC(=O)N5 |
−3.7
± 0.3
|
2.7
± 0.2
|
4039 |
EN300-36065_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCS(=O)(=O)N |
−3.7
± 0.5
|
2.7
± 0.3
|
4040 |
EN300-102853_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc6nnnn6c5 |
−3.7
± 0.3
|
2.7
± 0.2
|
4041 |
EN300-1273172_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnc(cn5)C(=O)N |
−3.7
± 0.3
|
2.7
± 0.2
|
4042 |
EN300-180982_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)N6CCOCC6 |
−3.7
± 0.3
|
2.7
± 0.2
|
4043 |
EN300-263418_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6n5ccc(n6)C#N |
−3.7
± 0.3
|
2.7
± 0.3
|
4044 |
EN300-227055_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CC(=O)NC5=O |
−3.7
± 0.2
|
2.7
± 0.2
|
4045 |
EN300-298550_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)N6CCOC6=O |
−3.7
± 0.2
|
2.7
± 0.2
|
4046 |
EN300-34636_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccc(=O)[nH]5 |
−3.7
± 0.3
|
2.7
± 0.2
|
4047 |
EN300-13499_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCCNC(=O)N |
−3.6
± 0.3
|
2.6
± 0.3
|
4048 |
EN300-6486793_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCCC5)S(=O)(=O)N |
−3.6
± 0.2
|
2.6
± 0.1
|
4049 |
EN300-41518_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCOCC5 |
−3.6
± 0.3
|
2.6
± 0.2
|
4050 |
EN300-73703_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCS(=O)(=O)NCC5CCC5 |
−3.6
± 0.7
|
2.6
± 0.5
|
4051 |
EN300-60164_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CCCS5(=O)=O |
−3.6
± 0.3
|
2.6
± 0.2
|
4052 |
EN300-233407_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCCCN5CCO |
−3.6
± 0.3
|
2.6
± 0.2
|
4053 |
EN300-59879_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCC(CC5)CO |
−3.6
± 0.3
|
2.6
± 0.2
|
4054 |
EN300-51335_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCS(=O)(=O)N |
−3.6
± 0.3
|
2.6
± 0.3
|
4055 |
EN300-239233_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5c(=O)cccn5 |
−3.6
± 0.3
|
2.6
± 0.2
|
4056 |
EN300-59757_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCCNC5=O |
−3.6
± 0.4
|
2.6
± 0.3
|
4057 |
EN300-210110_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn(nn5)C6CC6 |
−3.6
± 0.3
|
2.6
± 0.2
|
4058 |
EN300-133821_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)CC(C6CC6)O |
−3.6
± 0.3
|
2.6
± 0.2
|
4059 |
EN300-129384_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCCCNC5=O |
−3.5
± 0.1
|
2.6
± 0.1
|
4060 |
EN300-199149_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CN5CCOCC5)CO |
−3.5
± 0.4
|
2.6
± 0.3
|
4061 |
EN300-60837_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc6nncn6c5 |
−3.5
± 0.3
|
2.6
± 0.2
|
4062 |
EN300-98214_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CCCC5=O |
−3.5
± 0.4
|
2.6
± 0.3
|
4063 |
EN300-62808_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnc[nH]5 |
−3.5
± 0.2
|
2.6
± 0.2
|
4064 |
EN300-57990_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]nnn5 |
−3.5
± 0.3
|
2.6
± 0.2
|
4065 |
EN300-184355_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(C(=O)N)O |
−3.5
± 0.4
|
2.5
± 0.3
|
4066 |
EN300-134204_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCc5[nH]nnn5 |
−3.5
± 0.4
|
2.5
± 0.3
|
4067 |
EN300-318110_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)C(C(=O)N)F |
−3.5
± 0.3
|
2.5
± 0.2
|
4068 |
EN300-33667_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCS(=O)(=O)NC5CC5 |
−3.5
± 0.4
|
2.5
± 0.3
|
4069 |
EN300-69144_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)N5CCCC5 |
−3.5
± 0.2
|
2.5
± 0.2
|
4070 |
EN300-702756_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CS(=O)(=O)CC(=O)N5 |
−3.5
± 0.3
|
2.5
± 0.2
|
4071 |
EN300-315836_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5[nH]ccn5 |
−3.5
± 0.2
|
2.5
± 0.1
|
4072 |
EN300-7535791_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCC(CC5)(CO)CO |
−3.4
± 0.4
|
2.5
± 0.3
|
4073 |
EN300-65352_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)c5ncccn5 |
−3.4
± 0.3
|
2.5
± 0.2
|
4074 |
EN300-761719_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@H](CO)O |
−3.4
± 0.4
|
2.5
± 0.3
|
4075 |
EN300-102071_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccnc(c5)C(=O)N |
−3.4
± 0.3
|
2.5
± 0.2
|
4076 |
EN300-1587825_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CC6(C5)COC6 |
−3.4
± 0.4
|
2.5
± 0.3
|
4077 |
EN300-145616_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5cnc[nH]5 |
−3.4
± 0.3
|
2.4
± 0.2
|
4078 |
EN300-2666482_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cncc(n5)n6ccnc6 |
−3.3
± 0.2
|
2.4
± 0.2
|
4079 |
EN300-132613_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c(scn5)S(=O)(=O)N |
−3.3
± 0.3
|
2.4
± 0.2
|
4080 |
EN300-257058_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5C[C@H]5N6CCOCC6 |
−3.3
± 0.3
|
2.4
± 0.2
|
4081 |
EN300-248542_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CCC(CC5)O |
−3.3
± 0.2
|
2.4
± 0.2
|
4082 |
EN300-6733995_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCNS(=O)(=O)C(F)F |
−3.3
± 0.4
|
2.4
± 0.3
|
4083 |
EN300-1072874_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCNC(=O)CC5 |
−3.3
± 0.3
|
2.4
± 0.2
|
4084 |
EN300-205518_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCS(=O)(=O)CC5)O |
−3.3
± 0.2
|
2.4
± 0.2
|
4085 |
EN300-173536_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCS5(=O)=O |
−3.3
± 0.4
|
2.4
± 0.3
|
4086 |
EN300-75807_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCS(=O)(=O)CC5 |
−3.2
± 0.3
|
2.4
± 0.2
|
4087 |
EN300-249245_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(C(F)F)O |
−3.2
± 0.3
|
2.4
± 0.2
|
4088 |
EN300-33667_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCS(=O)(=O)NC5CC5 |
−3.2
± 0.6
|
2.3
± 0.4
|
4089 |
EN300-39439_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCC(=O)N |
−3.2
± 0.3
|
2.3
± 0.2
|
4090 |
EN300-108422_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)CC(=O)N |
−3.2
± 0.2
|
2.3
± 0.2
|
4091 |
EN300-227021_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCc5[nH]cnn5 |
−3.2
± 0.3
|
2.3
± 0.2
|
4092 |
EN300-159881_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CCCOCC5 |
−3.1
± 0.3
|
2.3
± 0.2
|
4093 |
EN300-74856_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCCS(=O)(=O)C5 |
−3.1
± 0.3
|
2.3
± 0.2
|
4094 |
EN300-1657545_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5nc6n(n5)CCC(=O)N6 |
−3.1
± 0.3
|
2.3
± 0.2
|
4095 |
EN300-7537340_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCC(=O)NC5=O)CO |
−3.0
± 0.2
|
2.2
± 0.1
|
4096 |
EN300-153245_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@@H](C[C@H]5CO)O |
−3.0
± 0.3
|
2.2
± 0.2
|
4097 |
EN300-325737_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c6ccccn6nn5 |
−3.0
± 0.3
|
2.2
± 0.2
|
4098 |
JOH-UNI-f51e3bbc-1
|
|
c1ccc2c(c1)c(c[nH]c2=O)NC(=O)C3CCOc4c3cc(cc4)Cl |
−3.0
± 0.2
|
2.2
± 0.2
|
4099 |
EN300-68350_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOCC5)CO |
−3.0
± 0.4
|
2.2
± 0.3
|
4100 |
EN300-7427197_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCN(CC5)C6COC6 |
−3.0
± 0.3
|
2.2
± 0.2
|