Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3901 |
EN300-21473_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5[nH]c(=O)c6c(n5)nc[nH]6 |
−4.4
± 0.2
|
3.2
± 0.2
|
3902 |
EN300-28262_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc6n5ncn6 |
−4.4
± 0.2
|
3.2
± 0.2
|
3903 |
EN300-1268087_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)c6[nH]nnn6 |
−4.4
± 0.4
|
3.2
± 0.3
|
3904 |
EN300-256939_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CCOC5 |
−4.4
± 0.2
|
3.2
± 0.1
|
3905 |
EN300-43972_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]cnn5 |
−4.4
± 0.2
|
3.2
± 0.2
|
3906 |
EN300-262136_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CCC6 |
−4.3
± 0.4
|
3.2
± 0.3
|
3907 |
EN300-1720784_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC[C@@H](CO)O |
−4.3
± 0.3
|
3.2
± 0.2
|
3908 |
EN300-62192_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CC(=O)NC(=O)C5 |
−4.3
± 0.3
|
3.2
± 0.2
|
3909 |
EN300-22410_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCNC(=O)C5CC5 |
−4.3
± 0.2
|
3.2
± 0.1
|
3910 |
EN300-21200_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c(nccn5)C(=O)N |
−4.3
± 0.3
|
3.2
± 0.2
|
3911 |
EN300-252044_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5C[C@@H]5N6CCOCC6 |
−4.3
± 0.3
|
3.2
± 0.2
|
3912 |
EN300-6491697_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5cccc(=O)[nH]5 |
−4.3
± 0.3
|
3.1
± 0.2
|
3913 |
EN300-49839_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCN5CCC(CC5)O |
−4.3
± 0.2
|
3.1
± 0.2
|
3914 |
EN300-7444335_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOC5)c6[nH]nnn6 |
−4.3
± 0.3
|
3.1
± 0.2
|
3915 |
EN300-7426624_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnnn5C6CCC6 |
−4.3
± 0.3
|
3.1
± 0.2
|
3916 |
EN300-98143_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c(cn[nH]5)F |
−4.3
± 0.2
|
3.1
± 0.2
|
3917 |
EN300-71106_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCc6ncnn6C5 |
−4.3
± 0.2
|
3.1
± 0.1
|
3918 |
EN300-307190_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnc6n5CCOC6 |
−4.3
± 0.3
|
3.1
± 0.2
|
3919 |
EN300-321161_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCN5CCOCC5 |
−4.3
± 0.2
|
3.1
± 0.2
|
3920 |
EN300-1178005_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(on5)C#N |
−4.3
± 0.3
|
3.1
± 0.2
|
3921 |
EN300-1425899_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CC[C@@H](C5)CS(=O)(=O)N |
−4.3
± 0.4
|
3.1
± 0.3
|
3922 |
EN300-129820_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCNC(=O)C5 |
−4.3
± 0.3
|
3.1
± 0.2
|
3923 |
EN300-90372_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5c[nH]c(=O)[nH]c5=O |
−4.3
± 0.3
|
3.1
± 0.2
|
3924 |
EN300-7183657_2
|
|
C[C@]1(C[C@@H](C1)C(=O)NC[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5)O |
−4.3
± 0.2
|
3.1
± 0.2
|
3925 |
EN300-75875_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccnnc5 |
−4.3
± 0.3
|
3.1
± 0.2
|
3926 |
EN300-300825_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOCC5)CCO |
−4.3
± 0.2
|
3.1
± 0.2
|
3927 |
EN300-1605566_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CN6CCN5CC6 |
−4.3
± 0.3
|
3.1
± 0.2
|
3928 |
EN300-121078_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CC5)CCO |
−4.3
± 0.3
|
3.1
± 0.2
|
3929 |
EN300-1268087_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)c6[nH]nnn6 |
−4.3
± 0.3
|
3.1
± 0.2
|
3930 |
EN300-198633_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCCCNC5=O |
−4.3
± 0.2
|
3.1
± 0.2
|
3931 |
EN300-53591_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(CC5)NC(=O)N |
−4.3
± 0.3
|
3.1
± 0.2
|
3932 |
EN300-6763470_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(C(=O)N)C(F)(F)F |
−4.3
± 0.2
|
3.1
± 0.1
|
3933 |
EN300-94202_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(C(=O)C5)CCO |
−4.3
± 0.3
|
3.1
± 0.2
|
3934 |
EN300-246501_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)C6CS(=O)(=O)C6 |
−4.3
± 0.3
|
3.1
± 0.2
|
3935 |
EN300-370792_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)c5cnccn5 |
−4.3
± 0.3
|
3.1
± 0.2
|
3936 |
EN300-77265_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(=O)c(co5)O |
−4.3
± 0.3
|
3.1
± 0.2
|
3937 |
EN300-80855_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(C5CCOC5)O |
−4.3
± 0.2
|
3.1
± 0.2
|
3938 |
EN300-256798_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCc6nnnn6CC5 |
−4.3
± 0.2
|
3.1
± 0.2
|
3939 |
EN300-52645_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5cnn(c5)CCO |
−4.2
± 0.2
|
3.1
± 0.1
|
3940 |
EN300-14006_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCS(=O)(=O)C5 |
−4.2
± 0.3
|
3.1
± 0.2
|
3941 |
EN300-246808_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCCS5(=O)=O |
−4.2
± 0.2
|
3.1
± 0.1
|
3942 |
EN300-6734454_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC56CC(C5)(OC6)CO |
−4.2
± 0.3
|
3.1
± 0.2
|
3943 |
EN300-76707_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCCC5)C(=O)N |
−4.2
± 0.3
|
3.1
± 0.2
|
3944 |
EN300-1698650_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCn5ccnn5 |
−4.2
± 0.2
|
3.1
± 0.2
|
3945 |
EN300-260621_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCc5ccc(=O)[nH]c5 |
−4.2
± 0.3
|
3.1
± 0.2
|
3946 |
EN300-322161_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCn6ccnc6C5 |
−4.2
± 0.3
|
3.1
± 0.2
|
3947 |
EN300-373791_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccnn5CC#N |
−4.2
± 0.2
|
3.1
± 0.2
|
3948 |
EN300-817811_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(=O)[nH]cn5 |
−4.2
± 0.2
|
3.1
± 0.1
|
3949 |
EN300-97661_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc[nH]c(=O)c5 |
−4.2
± 0.2
|
3.1
± 0.2
|
3950 |
EN300-637522_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C6CCC5(CC6)C(=O)N |
−4.2
± 0.3
|
3.1
± 0.2
|
3951 |
EN300-129441_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccc6n5ncn6 |
−4.2
± 0.3
|
3.1
± 0.2
|
3952 |
EN300-221418_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)CN6CCOCC6 |
−4.2
± 0.4
|
3.1
± 0.3
|
3953 |
EN300-219427_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCn6c(c(nn6)CO)C5 |
−4.2
± 0.3
|
3.1
± 0.2
|
3954 |
DAR-DIA-0d514e7d-5
|
|
C[C@H]1COc2c(cc(cc2NC3CCCC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−4.2
± 0.2
|
3.1
± 0.1
|
3955 |
EN300-68735_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)N6CCOCC6 |
−4.2
± 0.2
|
3.1
± 0.1
|
3956 |
EN300-171752_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCOC5 |
−4.2
± 0.2
|
3.1
± 0.1
|
3957 |
EN300-188377_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccnc6c5[nH]nn6 |
−4.2
± 0.3
|
3.1
± 0.2
|
3958 |
EN300-7435482_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C6(C5)CCOCC6)O |
−4.2
± 0.2
|
3.1
± 0.2
|
3959 |
EN300-39826_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5nc6ncccn6n5 |
−4.2
± 0.3
|
3.1
± 0.2
|
3960 |
EN300-74706_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCC(CC5)C(=O)N |
−4.2
± 0.4
|
3.0
± 0.3
|
3961 |
EN300-1689158_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc([nH]n5)C(=O)N |
−4.2
± 0.3
|
3.0
± 0.2
|
3962 |
EN300-366852_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)c6[nH]nnn6 |
−4.2
± 0.3
|
3.0
± 0.2
|
3963 |
MAK-UNK-3875bbc8-3
|
|
CN(c1cncc2c1cccc2)C(=O)C3CCOc4c3cccc4 |
−4.2
± 0.1
|
3.0
± 0.1
|
3964 |
EN300-67573_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NC5CCOCC5 |
−4.1
± 0.3
|
3.0
± 0.2
|
3965 |
EN300-27476_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5c(=O)n6ccccc6n5 |
−4.1
± 0.3
|
3.0
± 0.2
|
3966 |
EN300-2010167_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccc6n5nnc6 |
−4.1
± 0.3
|
3.0
± 0.2
|
3967 |
EN300-6762830_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5C[C@@H]([C@H]([C@H]5O)O)O |
−4.1
± 0.3
|
3.0
± 0.2
|
3968 |
EN300-252018_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c6c(nc[nH]6)ncn5 |
−4.1
± 0.2
|
3.0
± 0.2
|
3969 |
EN300-75807_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCS(=O)(=O)CC5 |
−4.1
± 0.1
|
3.0
± 0.1
|
3970 |
EN300-384280_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5ccc(=O)[nH]c5=O |
−4.1
± 0.3
|
3.0
± 0.2
|
3971 |
EN300-333468_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnn(c5Cl)CCO |
−4.1
± 0.3
|
3.0
± 0.2
|
3972 |
EN300-11441_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cc(=O)[nH]c(=O)[nH]5 |
−4.1
± 0.3
|
3.0
± 0.2
|
3973 |
ADA-UCB-dc2b944c-14
|
|
C[C@H]1COc2ccc(cc2[C@H]1C(=O)Nc3cncc4c3cccc4)Cl |
−4.1
± 0.2
|
3.0
± 0.1
|
3974 |
EN300-6477139_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CCS(=O)(=O)CC6 |
−4.1
± 0.3
|
3.0
± 0.2
|
3975 |
EN300-60957_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCS(=O)(=O)N5CCOCC5 |
−4.1
± 0.7
|
3.0
± 0.5
|
3976 |
EN300-1608240_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(=O)N6C5COCC6 |
−4.1
± 0.3
|
3.0
± 0.2
|
3977 |
EN300-345754_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC5CCO |
−4.1
± 0.2
|
3.0
± 0.1
|
3978 |
EN300-227398_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCCN(C5)CCO |
−4.1
± 0.2
|
3.0
± 0.1
|
3979 |
EN300-254121_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(c5cnc[nH]5)O |
−4.1
± 0.2
|
3.0
± 0.2
|
3980 |
EN300-6732784_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCc6c(c(n[nH]6)CO)C5 |
−4.1
± 0.3
|
3.0
± 0.2
|
3981 |
EN300-171605_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC5CS(=O)(=O)C5 |
−4.1
± 0.2
|
3.0
± 0.2
|
3982 |
EN300-1704113_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)N5CC=CC5 |
−4.1
± 0.3
|
3.0
± 0.2
|
3983 |
EN300-318305_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CC6(C5)CS(=O)(=O)C6 |
−4.1
± 0.2
|
3.0
± 0.2
|
3984 |
VLA-UCB-05e51b3f-7
|
|
CC(=O)N1CCN(CC1)CC(=O)N(c2cncc3c2cccc3)C(=O)[C@H]4CCOc5c4cc(cc5)Cl |
−4.1
± 0.6
|
3.0
± 0.4
|
3985 |
EN300-42154_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CS(=O)(=O)C5CCCC5 |
−4.0
± 0.3
|
2.9
± 0.2
|
3986 |
EN300-6760451_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5nnc6n5cccc6 |
−4.0
± 0.3
|
2.9
± 0.2
|
3987 |
EN300-1688980_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCCCNS(=O)(=O)CC5 |
−4.0
± 0.5
|
2.9
± 0.3
|
3988 |
EN300-746311_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c[nH]c6c5c(=O)[nH]cn6 |
−4.0
± 0.2
|
2.9
± 0.2
|
3989 |
EN300-256513_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)CC(=O)N |
−4.0
± 0.3
|
2.9
± 0.2
|
3990 |
EN300-147397_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnc6nccn6c5 |
−4.0
± 0.4
|
2.9
± 0.3
|
3991 |
EN300-40888_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC(=O)N |
−4.0
± 0.3
|
2.9
± 0.2
|
3992 |
EN300-58259_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NCC(F)(F)F |
−4.0
± 0.2
|
2.9
± 0.1
|
3993 |
EN300-39278_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCS(=O)(=O)CC5 |
−4.0
± 0.3
|
2.9
± 0.2
|
3994 |
EN300-114540_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CN6CCN5CC6 |
−4.0
± 0.3
|
2.9
± 0.2
|
3995 |
EN300-322100_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccnc6n5ncc6 |
−4.0
± 0.3
|
2.9
± 0.2
|
3996 |
EN300-6734977_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC56CC(C5)OC6 |
−4.0
± 0.3
|
2.9
± 0.2
|
3997 |
EN300-383904_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCNC(=O)CO |
−4.0
± 0.4
|
2.9
± 0.3
|
3998 |
EN300-309106_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn6cnnc6cn5 |
−4.0
± 0.3
|
2.9
± 0.2
|
3999 |
EN300-226921_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCCN5CCCO |
−4.0
± 0.2
|
2.9
± 0.2
|
4000 |
EN300-7427921_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)n6cnnc6 |
−4.0
± 0.3
|
2.9
± 0.2
|