Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3801 |
EN300-215014_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC5(CCCOC5)O |
−4.6
± 0.2
|
3.4
± 0.2
|
3802 |
EN300-244278_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc6n(n5)CCOC6 |
−4.6
± 0.3
|
3.4
± 0.2
|
3803 |
EN300-256759_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCC(=O)NCC5 |
−4.6
± 0.2
|
3.4
± 0.1
|
3804 |
EN300-657211_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5[nH]c(nn5)C6CC6 |
−4.6
± 0.3
|
3.4
± 0.2
|
3805 |
EN300-80390_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5ccn(n5)CCC(=O)N |
−4.6
± 0.2
|
3.4
± 0.2
|
3806 |
EN300-131690_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC(C5)c6ncon6 |
−4.6
± 0.3
|
3.4
± 0.2
|
3807 |
EN300-7237143_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCc6c([nH]c(=O)[nH]6)C5 |
−4.6
± 0.2
|
3.4
± 0.2
|
3808 |
EN300-144606_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn[nH]c5S(=O)(=O)N |
−4.6
± 0.3
|
3.4
± 0.2
|
3809 |
EN300-253681_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CCNC5=O |
−4.6
± 0.2
|
3.4
± 0.2
|
3810 |
EN300-260603_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5c[nH]c(=O)[nH]5 |
−4.6
± 0.3
|
3.4
± 0.2
|
3811 |
EN300-2011576_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5Cc6c(nccn6)C5 |
−4.6
± 0.3
|
3.4
± 0.2
|
3812 |
EN300-86205_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5c(=O)[nH]cnc5O |
−4.6
± 0.3
|
3.4
± 0.2
|
3813 |
EN300-378836_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCCS5(=O)=O |
−4.6
± 0.3
|
3.4
± 0.2
|
3814 |
EN300-59879_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCC(CC5)CO |
−4.6
± 0.3
|
3.4
± 0.2
|
3815 |
EN300-1440321_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCC5)S(=O)(=O)N |
−4.6
± 0.3
|
3.4
± 0.2
|
3816 |
EN300-39843_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCS(=O)(=O)CC5 |
−4.6
± 0.4
|
3.3
± 0.3
|
3817 |
EN300-359842_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c6ccnn6ccn5 |
−4.6
± 0.3
|
3.3
± 0.2
|
3818 |
EN300-905492_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CN(C5)c6ncc(cn6)F |
−4.6
± 0.3
|
3.3
± 0.2
|
3819 |
EN300-42819_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCC(=O)NC5 |
−4.6
± 0.3
|
3.3
± 0.2
|
3820 |
EN300-114593_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnn6c5cccn6 |
−4.6
± 0.3
|
3.3
± 0.2
|
3821 |
EN300-198633_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCCCNC5=O |
−4.6
± 0.2
|
3.3
± 0.1
|
3822 |
EN300-204507_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(CO)F |
−4.6
± 0.2
|
3.3
± 0.1
|
3823 |
EN300-52167_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5ccn(n5)CC(=O)N |
−4.6
± 0.3
|
3.3
± 0.2
|
3824 |
EN300-1721667_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NC5CCC5 |
−4.6
± 0.3
|
3.3
± 0.2
|
3825 |
EN300-71125_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCn6cnnc6C5 |
−4.6
± 0.3
|
3.3
± 0.2
|
3826 |
EN300-172179_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCOC5=O |
−4.6
± 0.3
|
3.3
± 0.2
|
3827 |
EN300-148321_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)C6CCOC6 |
−4.6
± 0.2
|
3.3
± 0.1
|
3828 |
EN300-59478_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCC(=O)N |
−4.6
± 0.4
|
3.3
± 0.3
|
3829 |
EN300-1609231_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CC(C5)CO)C(=O)N |
−4.6
± 0.3
|
3.3
± 0.2
|
3830 |
EN300-6732769_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)C6CC(=O)NC6=O |
−4.6
± 0.2
|
3.3
± 0.2
|
3831 |
EN300-263346_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5c(=O)n6c(n5)CCCC6 |
−4.6
± 0.3
|
3.3
± 0.2
|
3832 |
EN300-7431651_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CN(C5)C6COC6 |
−4.5
± 0.3
|
3.3
± 0.2
|
3833 |
EN300-761209_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnn(c5)CCO |
−4.5
± 0.3
|
3.3
± 0.2
|
3834 |
EN300-20345_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCOCC5 |
−4.5
± 0.4
|
3.3
± 0.3
|
3835 |
JAG-UCB-706446eb-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)O |
−4.5
± 0.2
|
3.3
± 0.2
|
3836 |
EN300-29228_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCn6c(cnn6)C5 |
−4.5
± 0.3
|
3.3
± 0.2
|
3837 |
EN300-7370063_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)CO |
−4.5
± 0.2
|
3.3
± 0.1
|
3838 |
EN300-233786_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCS(=O)(=O)C5)O |
−4.5
± 0.3
|
3.3
± 0.2
|
3839 |
JOH-SUS-a69c159d-3
|
|
c1ccc2c(c1)c(cnc2C(F)F)NC(=O)C3CCOc4c3cc(cc4)Cl |
−4.5
± 0.1
|
3.30
± 0.09
|
3840 |
EN300-83529_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5nc6ncccn6n5 |
−4.5
± 0.2
|
3.3
± 0.2
|
3841 |
EN300-225165_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CC(=O)NC(=O)C5 |
−4.5
± 0.4
|
3.3
± 0.3
|
3842 |
EN300-7456562_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCC(=O)NC5=O |
−4.5
± 0.3
|
3.3
± 0.2
|
3843 |
EN300-244947_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5c[nH]nn5 |
−4.5
± 0.3
|
3.3
± 0.2
|
3844 |
EN300-301703_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOCC5)C(=O)N |
−4.5
± 0.2
|
3.3
± 0.2
|
3845 |
EN300-1704723_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn(nn5)CCCF |
−4.5
± 0.3
|
3.3
± 0.2
|
3846 |
EN300-6743433_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccn6c(c5)cnn6 |
−4.5
± 0.3
|
3.3
± 0.2
|
3847 |
EN300-317867_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCNC(=O)C5 |
−4.5
± 0.3
|
3.3
± 0.2
|
3848 |
EN300-74706_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCC(CC5)C(=O)N |
−4.5
± 0.3
|
3.3
± 0.2
|
3849 |
EN300-59879_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCC(CC5)CO |
−4.5
± 0.5
|
3.3
± 0.3
|
3850 |
EN300-67050_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCS(=O)(=O)CC5 |
−4.5
± 0.3
|
3.3
± 0.2
|
3851 |
EN300-7426781_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c6cccn6ncn5 |
−4.5
± 0.2
|
3.3
± 0.2
|
3852 |
EN300-107493_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCNC(=O)C5 |
−4.5
± 0.2
|
3.3
± 0.2
|
3853 |
EN300-6730698_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)N6CC(C6)O |
−4.5
± 0.2
|
3.3
± 0.2
|
3854 |
EN300-02623_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5[nH]c(nn5)CCCO |
−4.5
± 0.2
|
3.3
± 0.2
|
3855 |
EN300-41307_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5cnn(c5)CC(=O)N |
−4.5
± 0.2
|
3.3
± 0.2
|
3856 |
EN300-110245_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCS(=O)(=O)CC5CC5 |
−4.5
± 0.5
|
3.3
± 0.4
|
3857 |
EN300-31147_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCNC(=O)C5CC5 |
−4.5
± 0.3
|
3.3
± 0.2
|
3858 |
EN300-21473_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5[nH]c(=O)c6c(n5)nc[nH]6 |
−4.5
± 0.2
|
3.3
± 0.2
|
3859 |
EN300-204161_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5ccc[nH]c5=O |
−4.5
± 0.2
|
3.3
± 0.2
|
3860 |
EN300-205486_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cnccc5O |
−4.5
± 0.3
|
3.3
± 0.2
|
3861 |
EN300-207543_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CN5CCCCC5)CO |
−4.5
± 0.4
|
3.3
± 0.3
|
3862 |
EN300-86205_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5c(=O)[nH]cnc5O |
−4.5
± 0.2
|
3.3
± 0.2
|
3863 |
EN300-2969289_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCCOC5)CO |
−4.5
± 0.4
|
3.3
± 0.3
|
3864 |
EN300-248542_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCC(CC5)O |
−4.5
± 0.2
|
3.3
± 0.2
|
3865 |
EN300-141942_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCOCC5)O |
−4.5
± 0.2
|
3.3
± 0.2
|
3866 |
EN300-1587825_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CC6(C5)COC6 |
−4.5
± 0.3
|
3.3
± 0.2
|
3867 |
ALP-POS-d3acb8cc-3
|
|
C[C@H]1C[C@@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.5
± 0.2
|
3.3
± 0.1
|
3868 |
EN300-235010_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(c(=O)[nH]c5=O)C#N |
−4.5
± 0.3
|
3.2
± 0.2
|
3869 |
EN300-640698_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc([nH]c5=O)C#N |
−4.5
± 0.3
|
3.2
± 0.2
|
3870 |
EN300-7433864_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c[nH]c(=O)n(c5=O)C6CC6 |
−4.4
± 0.3
|
3.2
± 0.2
|
3871 |
EN300-141464_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NCC5(CC5)C#N |
−4.4
± 0.3
|
3.2
± 0.2
|
3872 |
EN300-343433_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCc5c[nH]c(=O)nc5 |
−4.4
± 0.4
|
3.2
± 0.3
|
3873 |
EN300-20181_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)CCO |
−4.4
± 0.4
|
3.2
± 0.3
|
3874 |
EN300-305996_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5COC(=O)N5 |
−4.4
± 0.2
|
3.2
± 0.2
|
3875 |
EN300-260405_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CCC(C6)O |
−4.4
± 0.2
|
3.2
± 0.1
|
3876 |
EN300-122340_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCSCC5)O |
−4.4
± 0.3
|
3.2
± 0.2
|
3877 |
EN300-92012_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5C(=O)CCCC5=O |
−4.4
± 0.3
|
3.2
± 0.2
|
3878 |
EN300-1086911_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nc(cs5)c6[nH]nnn6 |
−4.4
± 0.3
|
3.2
± 0.2
|
3879 |
EN300-383906_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CNC(=O)N5CCCC5 |
−4.4
± 0.3
|
3.2
± 0.2
|
3880 |
EN300-311920_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCS(=O)(=O)C5)F |
−4.4
± 0.3
|
3.2
± 0.2
|
3881 |
EN300-1081929_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CCS(=O)(=O)CC6C5 |
−4.4
± 0.2
|
3.2
± 0.1
|
3882 |
EN300-141628_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc(c5)S(=O)(=O)N |
−4.4
± 0.3
|
3.2
± 0.2
|
3883 |
EN300-44993_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(cnc5)C(=O)N |
−4.4
± 0.2
|
3.2
± 0.2
|
3884 |
EN300-52212_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCCN(C5)CC(=O)N |
−4.4
± 0.3
|
3.2
± 0.2
|
3885 |
EN300-98690_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6n5cccn6 |
−4.4
± 0.3
|
3.2
± 0.2
|
3886 |
EN300-6489476_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CCNC(=O)C6 |
−4.4
± 0.3
|
3.2
± 0.2
|
3887 |
EN300-7465104_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(C5)(C6(CCC6)O)O |
−4.4
± 0.4
|
3.2
± 0.3
|
3888 |
EN300-6474933_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCOC5CCS(=O)(=O)C5 |
−4.4
± 0.2
|
3.2
± 0.1
|
3889 |
EN300-57126_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(CN5CCCC5=O)O |
−4.4
± 0.6
|
3.2
± 0.4
|
3890 |
EN300-41375_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCCC5 |
−4.4
± 0.3
|
3.2
± 0.2
|
3891 |
EN300-59386_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc(s5)S(=O)(=O)N |
−4.4
± 0.3
|
3.2
± 0.2
|
3892 |
EN300-124964_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCS(=O)CC5 |
−4.4
± 0.2
|
3.2
± 0.2
|
3893 |
EN300-7438185_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc6nncn6nc5 |
−4.4
± 0.3
|
3.2
± 0.2
|
3894 |
EN300-259230_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCOCC5)c6[nH]nnn6 |
−4.4
± 0.4
|
3.2
± 0.3
|
3895 |
EN300-1722465_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)N6CC(C6)O |
−4.4
± 0.4
|
3.2
± 0.3
|
3896 |
EN300-187385_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5ccc(=O)[nH]c5 |
−4.4
± 0.3
|
3.2
± 0.2
|
3897 |
EN300-60035_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCCNC5=O |
−4.4
± 0.2
|
3.2
± 0.1
|
3898 |
EN300-93574_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCS(=O)C5 |
−4.4
± 0.2
|
3.2
± 0.2
|
3899 |
EN300-195590_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCCNC(=O)C5 |
−4.4
± 0.2
|
3.2
± 0.1
|
3900 |
EN300-123712_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc(n5)n6cncn6 |
−4.4
± 0.3
|
3.2
± 0.2
|