Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3601 |
EN300-364890_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC[C@@H]5C(=O)N |
−5.0
± 0.3
|
3.7
± 0.2
|
3602 |
EN300-1588907_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5[C@H]6CCO[C@H]6C[C@H]5CO |
−5.0
± 0.3
|
3.7
± 0.2
|
3603 |
EN300-6733595_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC56CC(C5)(CO6)C(=O)N |
−5.0
± 0.3
|
3.7
± 0.2
|
3604 |
EN300-69144_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)N5CCCC5 |
−5.0
± 0.2
|
3.7
± 0.1
|
3605 |
EN300-41375_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCCC5 |
−5.0
± 0.3
|
3.7
± 0.2
|
3606 |
EN300-134536_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5ccnn5CCO |
−5.0
± 0.2
|
3.7
± 0.2
|
3607 |
EN300-69993_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCN(CC5)CCO |
−5.0
± 0.5
|
3.7
± 0.4
|
3608 |
EN300-154191_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)C5CCOCC5 |
−5.0
± 0.4
|
3.6
± 0.3
|
3609 |
EN300-133788_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOC5)CO |
−5.0
± 0.3
|
3.6
± 0.2
|
3610 |
EN300-378760_1
|
|
CS(=O)(=O)[C@H]1C[C@@H](C1)NC(=O)C[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5 |
−5.0
± 0.3
|
3.6
± 0.2
|
3611 |
EN300-10729_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCNC(=O)N |
−5.0
± 0.3
|
3.6
± 0.2
|
3612 |
EN300-22410_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCNC(=O)C5CC5 |
−5.0
± 0.2
|
3.6
± 0.1
|
3613 |
EN300-373552_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cncc(n5)F |
−5.0
± 0.3
|
3.6
± 0.2
|
3614 |
EN300-10729_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCNC(=O)N |
−5.0
± 0.3
|
3.6
± 0.2
|
3615 |
EN300-142432_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)NC(=O)C6CC6 |
−5.0
± 0.3
|
3.6
± 0.2
|
3616 |
EN300-72556_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC(C5)c6[nH]nnn6 |
−5.0
± 0.3
|
3.6
± 0.2
|
3617 |
EN300-223284_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5c[nH][nH]c5=O |
−5.0
± 0.2
|
3.6
± 0.2
|
3618 |
EN300-249093_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC5CC(=O)N |
−5.0
± 0.4
|
3.6
± 0.3
|
3619 |
EN300-16216_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)N |
−5.0
± 0.2
|
3.6
± 0.2
|
3620 |
EN300-195855_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cn5)n6cncn6 |
−5.0
± 0.1
|
3.6
± 0.1
|
3621 |
EN300-88656_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCS5(=O)=O |
−5.0
± 0.2
|
3.6
± 0.2
|
3622 |
EN300-129424_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCC5O |
−5.0
± 0.2
|
3.6
± 0.2
|
3623 |
EN300-307190_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6n5CCOC6 |
−5.0
± 0.3
|
3.6
± 0.2
|
3624 |
EN300-253365_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC(=O)Nc5[nH]ccn5 |
−5.0
± 0.3
|
3.6
± 0.2
|
3625 |
EN300-144935_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCN5CCCS5(=O)=O |
−5.0
± 0.2
|
3.6
± 0.1
|
3626 |
EN300-1273016_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCc6n5ncn6 |
−5.0
± 0.2
|
3.6
± 0.1
|
3627 |
EN300-313440_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CN(C5)C6CCOCC6 |
−5.0
± 0.3
|
3.6
± 0.2
|
3628 |
EN300-114312_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCC5 |
−5.0
± 0.3
|
3.6
± 0.2
|
3629 |
EN300-66126_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCCO |
−5.0
± 0.2
|
3.6
± 0.2
|
3630 |
EN300-7500408_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCCOC5)CO |
−5.0
± 0.2
|
3.6
± 0.1
|
3631 |
EN300-262604_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cnc(n5)C(=O)N |
−5.0
± 0.3
|
3.6
± 0.2
|
3632 |
EN300-87536_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CCCN5C(=O)N |
−5.0
± 0.2
|
3.6
± 0.2
|
3633 |
EN300-1666341_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5Cc6c(cn[nH]6)C5CO |
−5.0
± 0.2
|
3.6
± 0.2
|
3634 |
EN300-1600887_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC5COCCO5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3635 |
EN300-1696043_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn(nn5)C6COC6 |
−4.9
± 0.3
|
3.6
± 0.2
|
3636 |
EN300-35781_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6ccccn6c5=O |
−4.9
± 0.4
|
3.6
± 0.3
|
3637 |
EN300-154942_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5OCCO5 |
−4.9
± 0.2
|
3.6
± 0.1
|
3638 |
EN300-1428805_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5Cc6cncn6C(=O)N5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3639 |
EN300-7445396_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5Cc6c[nH]cc6S5(=O)=O |
−4.9
± 0.2
|
3.6
± 0.1
|
3640 |
EN300-190026_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)C5CCCO5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3641 |
EN300-6491316_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc6cnnn6c5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3642 |
EN300-208465_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CN6CCC5CC6)O |
−4.9
± 0.5
|
3.6
± 0.3
|
3643 |
EN300-195743_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H](CCO)CO |
−4.9
± 0.3
|
3.6
± 0.2
|
3644 |
EN300-36158_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5COCCO5 |
−4.9
± 0.2
|
3.6
± 0.1
|
3645 |
EN300-18610_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(C5)C(=O)N |
−4.9
± 0.2
|
3.6
± 0.2
|
3646 |
EN300-1719075_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(COC6)C(C5)(CO)F |
−4.9
± 0.3
|
3.6
± 0.2
|
3647 |
EN300-304771_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCN(C5=O)C6CC6 |
−4.9
± 0.3
|
3.6
± 0.2
|
3648 |
EDJ-MED-e4b030d8-1
|
|
C[C@@]1(c2cc(ccc2OCC1=O)Cl)C(=O)Nc3cncc4c3cccc4 |
−4.9
± 0.2
|
3.6
± 0.1
|
3649 |
EN300-263456_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(=O)n(n5)CCF |
−4.9
± 0.3
|
3.6
± 0.2
|
3650 |
EN300-7492698_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cn6c(n5)COCC6 |
−4.9
± 0.4
|
3.6
± 0.3
|
3651 |
EN300-264685_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CCOCC6 |
−4.9
± 0.4
|
3.6
± 0.3
|
3652 |
EN300-1587757_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCNS5(=O)=O |
−4.9
± 0.2
|
3.6
± 0.2
|
3653 |
EN300-111159_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c(cc(=O)[nH]n5)O |
−4.9
± 0.2
|
3.6
± 0.2
|
3654 |
EN300-84783_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CC=CC5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3655 |
EN300-257536_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5cc(=O)[nH]c(=O)[nH]5 |
−4.9
± 0.2
|
3.6
± 0.2
|
3656 |
EN300-79022_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccnn5 |
−4.9
± 0.2
|
3.6
± 0.2
|
3657 |
EN300-7434791_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@@H](CO)O |
−4.9
± 0.3
|
3.6
± 0.2
|
3658 |
EN300-11441_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cc(=O)[nH]c(=O)[nH]5 |
−4.9
± 0.2
|
3.6
± 0.2
|
3659 |
EN300-366468_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCNC(=O)C5 |
−4.9
± 0.2
|
3.6
± 0.2
|
3660 |
EN300-305984_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccn6c5nnn6 |
−4.9
± 0.4
|
3.6
± 0.3
|
3661 |
EN300-109119_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5cc([nH]n5)C(=O)N |
−4.9
± 0.2
|
3.6
± 0.2
|
3662 |
EN300-1932013_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(CC(F)(F)F)O |
−4.9
± 0.2
|
3.6
± 0.2
|
3663 |
EN300-80083_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCCC(=O)N5 |
−4.9
± 0.2
|
3.6
± 0.2
|
3664 |
EN300-126389_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5COC(=O)N5 |
−4.9
± 0.2
|
3.6
± 0.2
|
3665 |
EN300-81528_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCN5CCNC(=O)C5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3666 |
EN300-39033_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCNC(=O)c5ccncc5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3667 |
EN300-184266_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5CC(=O)N5 |
−4.9
± 0.2
|
3.6
± 0.2
|
3668 |
EN300-31553_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCS(=O)(=O)N |
−4.9
± 0.5
|
3.6
± 0.3
|
3669 |
EN300-191187_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(C5CCCO5)C(=O)N |
−4.9
± 0.2
|
3.6
± 0.1
|
3670 |
EN300-98099_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(cs5)S(=O)(=O)N |
−4.9
± 0.3
|
3.6
± 0.2
|
3671 |
EN300-42252_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn6cccnc6n5 |
−4.9
± 0.3
|
3.6
± 0.2
|
3672 |
EN300-7473032_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNC(=O)C5C(=O)N |
−4.9
± 0.2
|
3.6
± 0.1
|
3673 |
EN300-321213_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCN5CC[C@H](C5)O |
−4.9
± 0.3
|
3.6
± 0.2
|
3674 |
EN300-225920_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(c5ccccn5)C(=O)N |
−4.9
± 0.2
|
3.6
± 0.1
|
3675 |
EN300-1604951_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCNC(=O)C5 |
−4.9
± 0.4
|
3.6
± 0.3
|
3676 |
EN300-58864_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc(nc5)C(=O)N |
−4.9
± 0.3
|
3.5
± 0.2
|
3677 |
EN300-7440263_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCn6c(ncn6)C5 |
−4.9
± 0.2
|
3.5
± 0.2
|
3678 |
EN300-80230_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ncccn5 |
−4.9
± 0.2
|
3.5
± 0.1
|
3679 |
EN300-178515_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCC(=O)N |
−4.9
± 0.3
|
3.5
± 0.2
|
3680 |
EN300-657153_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC6(C5)CS(=O)(=O)C6 |
−4.9
± 0.2
|
3.5
± 0.2
|
3681 |
EN300-1709745_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cn(nn5)C6COC6 |
−4.9
± 0.3
|
3.5
± 0.2
|
3682 |
EN300-249804_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCOC(=O)N5 |
−4.9
± 0.2
|
3.5
± 0.1
|
3683 |
EN300-40006_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCNC(=O)c5cccnc5 |
−4.9
± 0.3
|
3.5
± 0.2
|
3684 |
EN300-115058_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCC5)C(=O)N |
−4.9
± 0.4
|
3.5
± 0.3
|
3685 |
EN300-6494606_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(c(=O)[nH]c5=O)Cl |
−4.9
± 0.3
|
3.5
± 0.2
|
3686 |
EN300-1073068_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCC(=O)NC5 |
−4.9
± 0.3
|
3.5
± 0.2
|
3687 |
EN300-19762_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)CCO |
−4.9
± 0.4
|
3.5
± 0.3
|
3688 |
EN300-45182_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCN5CCOC5=O |
−4.8
± 0.3
|
3.5
± 0.2
|
3689 |
EN300-251562_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnc6n5nccc6 |
−4.8
± 0.3
|
3.5
± 0.2
|
3690 |
EN300-146491_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5CCCC(=O)N5 |
−4.8
± 0.3
|
3.5
± 0.2
|
3691 |
EN300-6473108_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc6cccnn6n5 |
−4.8
± 0.2
|
3.5
± 0.2
|
3692 |
EN300-7470948_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCc5c(nco5)CO |
−4.8
± 0.3
|
3.5
± 0.2
|
3693 |
EN300-251851_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5[nH]nnn5 |
−4.8
± 0.3
|
3.5
± 0.2
|
3694 |
EN300-261210_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCOC5)C#N |
−4.8
± 0.2
|
3.5
± 0.1
|
3695 |
EN300-39785_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5ccn[nH]5 |
−4.8
± 0.2
|
3.5
± 0.1
|
3696 |
EN300-246808_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCCS5(=O)=O |
−4.8
± 0.3
|
3.5
± 0.2
|
3697 |
EN300-384557_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(c5cnc[nH]5)O |
−4.8
± 0.3
|
3.5
± 0.2
|
3698 |
EN300-318250_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCN(CC5)CC(=O)N |
−4.8
± 0.2
|
3.5
± 0.2
|
3699 |
EN300-19625_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCN5CCOCC5 |
−4.8
± 0.3
|
3.5
± 0.2
|
3700 |
EN300-205486_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cnccc5O |
−4.8
± 0.3
|
3.5
± 0.2
|