Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3501 |
EN300-223741_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)S(=O)(=O)N |
−5.2
± 0.2
|
3.8
± 0.2
|
3502 |
EN300-7492698_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5cn6c(n5)COCC6 |
−5.2
± 0.3
|
3.8
± 0.2
|
3503 |
EN300-6487630_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CS(=O)(=O)C5)CCO |
−5.2
± 0.3
|
3.8
± 0.2
|
3504 |
EN300-1720418_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5=NOCC5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3505 |
EN300-69313_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H](C5)O |
−5.2
± 0.3
|
3.8
± 0.2
|
3506 |
EN300-307198_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(COC5)CO |
−5.2
± 0.3
|
3.8
± 0.2
|
3507 |
EN300-6480951_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)C6CC(=O)NC6 |
−5.2
± 0.2
|
3.8
± 0.1
|
3508 |
EN300-264318_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CCOC(=O)N6 |
−5.2
± 0.3
|
3.8
± 0.2
|
3509 |
EN300-393334_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(C5)CC(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3510 |
EN300-35966_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5cccc(c5)S(=O)(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3511 |
EN300-7427198_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCN(C5)C6COC6 |
−5.2
± 0.2
|
3.8
± 0.2
|
3512 |
EN300-132613_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c(scn5)S(=O)(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3513 |
EN300-66290_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CC(=O)N)CC(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3514 |
EN300-195855_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(cn5)n6cncn6 |
−5.2
± 0.2
|
3.8
± 0.1
|
3515 |
EN300-322161_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCn6ccnc6C5 |
−5.2
± 0.3
|
3.8
± 0.3
|
3516 |
EN300-1609249_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC6(CC5)CS(=O)(=O)C6 |
−5.2
± 0.2
|
3.8
± 0.2
|
3517 |
EN300-105829_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCOC5)CCO |
−5.2
± 0.2
|
3.8
± 0.1
|
3518 |
JOH-UNI-f51e3bbc-3
|
|
c1ccc2c(c1)cnc(c2NC(=O)C3CCOc4c3cc(cc4)Cl)O |
−5.2
± 0.1
|
3.8
± 0.1
|
3519 |
EN300-1215712_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(COC5)O |
−5.2
± 0.3
|
3.8
± 0.2
|
3520 |
EN300-96808_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)OCC(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3521 |
EN300-1592151_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc6ncnn6c5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3522 |
EN300-244909_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCOCC5)CO |
−5.2
± 0.3
|
3.8
± 0.2
|
3523 |
EN300-124652_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC5CC(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3524 |
EN300-188650_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5[nH]ccn5 |
−5.1
± 0.3
|
3.8
± 0.2
|
3525 |
EN300-219609_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCn5cnccc5=O |
−5.1
± 0.3
|
3.7
± 0.2
|
3526 |
EN300-640503_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5C[C@H](C56CCOCC6)O |
−5.1
± 0.4
|
3.7
± 0.3
|
3527 |
EN300-6474933_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCOC5CCS(=O)(=O)C5 |
−5.1
± 0.2
|
3.7
± 0.1
|
3528 |
EN300-39305_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCS(=O)(=O)CC5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3529 |
EN300-19515_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCC(=O)N5 |
−5.1
± 0.2
|
3.7
± 0.1
|
3530 |
EN300-146051_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc(nc5)CO |
−5.1
± 0.3
|
3.7
± 0.2
|
3531 |
EN300-120480_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(nc5)S(=O)(=O)N |
−5.1
± 0.3
|
3.7
± 0.3
|
3532 |
EN300-6487134_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC56CC(C5)C(=O)NC6 |
−5.1
± 0.3
|
3.7
± 0.2
|
3533 |
EN300-1068231_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn6ccncc6n5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3534 |
EN300-51335_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCS(=O)(=O)N |
−5.1
± 0.3
|
3.7
± 0.2
|
3535 |
EN300-370951_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CCCC6=O |
−5.1
± 0.3
|
3.7
± 0.2
|
3536 |
EN300-252018_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6c(nc[nH]6)ncn5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3537 |
EN300-73620_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCS(=O)(=O)CC5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3538 |
EN300-1270299_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc(cn5)CO |
−5.1
± 0.3
|
3.7
± 0.2
|
3539 |
EN300-313197_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCn5cc(c(=O)[nH]c5=O)C#N |
−5.1
± 0.3
|
3.7
± 0.2
|
3540 |
EN300-113218_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CSC5CCOC5=O |
−5.1
± 0.2
|
3.7
± 0.2
|
3541 |
EN300-233407_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCCCN5CCO |
−5.1
± 0.3
|
3.7
± 0.2
|
3542 |
EN300-36096_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCCNC5=O |
−5.1
± 0.3
|
3.7
± 0.2
|
3543 |
EN300-210084_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCCC(=O)N5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3544 |
EN300-384234_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(c6cnn[nH]6)O |
−5.1
± 0.3
|
3.7
± 0.2
|
3545 |
EN300-7549555_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5coc(n5)CO |
−5.1
± 0.2
|
3.7
± 0.2
|
3546 |
EN300-29520_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5nccc6 |
−5.1
± 0.3
|
3.7
± 0.2
|
3547 |
EN300-7440089_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6nccn6c(=O)[nH]5 |
−5.1
± 0.2
|
3.7
± 0.2
|
3548 |
EN300-190253_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(cc(=O)o5)O |
−5.1
± 0.2
|
3.7
± 0.2
|
3549 |
EN300-157830_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(C5)OCCO |
−5.1
± 0.2
|
3.7
± 0.2
|
3550 |
EN300-1667046_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(c6ccn[nH]6)O |
−5.1
± 0.3
|
3.7
± 0.2
|
3551 |
EN300-1221623_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCn6c(ccn6)C5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3552 |
EN300-243697_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CN(C5)C(=O)C(F)(F)F |
−5.1
± 0.3
|
3.7
± 0.2
|
3553 |
EN300-29520_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnn6c5nccc6 |
−5.1
± 0.3
|
3.7
± 0.2
|
3554 |
EN300-821316_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CC(=O)NCC6O |
−5.1
± 0.3
|
3.7
± 0.2
|
3555 |
EN300-104395_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5CCCO5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3556 |
EN300-130656_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc(n5)C(=O)N |
−5.1
± 0.2
|
3.7
± 0.2
|
3557 |
EN300-318250_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCN(CC5)CC(=O)N |
−5.1
± 0.2
|
3.7
± 0.1
|
3558 |
EN300-23792_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(sc5)S(=O)(=O)N |
−5.1
± 0.3
|
3.7
± 0.2
|
3559 |
EN300-263418_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc6n5ccc(n6)C#N |
−5.1
± 0.2
|
3.7
± 0.2
|
3560 |
EN300-1723991_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCN5CCCNC5=O |
−5.1
± 0.3
|
3.7
± 0.2
|
3561 |
EN300-6762327_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(Cc5ccccn5)O |
−5.1
± 0.3
|
3.7
± 0.2
|
3562 |
EN300-359842_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6ccnn6ccn5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3563 |
EN300-1266218_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6c([nH]n5)nc[nH]c6=O |
−5.1
± 0.3
|
3.7
± 0.2
|
3564 |
EN300-7385329_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5Cc6nccn6C5 |
−5.1
± 0.2
|
3.7
± 0.2
|
3565 |
MAT-POS-11b63608-1
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3cc(cc4)Br |
−5.09
± 0.05
|
3.71
± 0.04
|
3566 |
EN300-122579_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCSCC5CO |
−5.1
± 0.2
|
3.7
± 0.2
|
3567 |
EN300-36850_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCNC(=O)C5CC5 |
−5.1
± 0.3
|
3.7
± 0.2
|
3568 |
EN300-71012_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCN(CC5)CCO |
−5.1
± 0.4
|
3.7
± 0.3
|
3569 |
EN300-113633_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCC(=O)NC5=O |
−5.1
± 0.2
|
3.7
± 0.2
|
3570 |
MAK-UNK-8be7dca9-10
|
|
c1ccc2c(c1)cncc2NC(=O)C3CC(Oc4c3cc(cc4)Cl)C(=O)O |
−5.1
± 0.1
|
3.70
± 0.07
|
3571 |
EN300-11714_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5ccccc5=O |
−5.1
± 0.3
|
3.7
± 0.2
|
3572 |
EN300-7349829_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(=O)NCC56CCC6 |
−5.1
± 0.4
|
3.7
± 0.3
|
3573 |
EN300-7444106_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCc6nnnn6C5 |
−5.1
± 0.2
|
3.7
± 0.2
|
3574 |
EN300-207092_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5(CCOCC5)O |
−5.1
± 0.3
|
3.7
± 0.2
|
3575 |
EN300-58880_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc(cn5)C(=O)N |
−5.1
± 0.3
|
3.7
± 0.2
|
3576 |
EN300-1272295_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CCCS6(=O)=O |
−5.1
± 0.3
|
3.7
± 0.2
|
3577 |
EN300-1215712_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(COC5)O |
−5.1
± 0.3
|
3.7
± 0.2
|
3578 |
EN300-1425677_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCCO5)CO |
−5.1
± 0.3
|
3.7
± 0.2
|
3579 |
EN300-180982_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CC5)N6CCOCC6 |
−5.1
± 0.3
|
3.7
± 0.2
|
3580 |
EN300-1723254_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CC(C6)O |
−5.1
± 0.4
|
3.7
± 0.3
|
3581 |
EN300-64297_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cncnc5 |
−5.1
± 0.2
|
3.7
± 0.2
|
3582 |
EN300-1087187_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CCC(=O)NC6C5 |
−5.1
± 0.2
|
3.7
± 0.1
|
3583 |
EN300-35778_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCC(CC5)C(=O)N |
−5.1
± 0.2
|
3.7
± 0.2
|
3584 |
EN300-247428_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn(nn5)CC6CC6 |
−5.1
± 0.3
|
3.7
± 0.2
|
3585 |
EN300-6494361_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CNC(=O)O6 |
−5.1
± 0.2
|
3.7
± 0.2
|
3586 |
EN300-49839_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCN5CCC(CC5)O |
−5.1
± 0.3
|
3.7
± 0.2
|
3587 |
EN300-154156_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(=O)NC5 |
−5.0
± 0.2
|
3.7
± 0.2
|
3588 |
EN300-204239_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(=O)[nH]c(n5)C6CC6 |
−5.0
± 0.2
|
3.7
± 0.2
|
3589 |
EN300-196612_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NCCF |
−5.0
± 0.2
|
3.7
± 0.2
|
3590 |
EN300-249764_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(C5CCC5)O |
−5.0
± 0.2
|
3.7
± 0.2
|
3591 |
EN300-6503694_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCNS(=O)(=O)C(F)F |
−5.0
± 0.4
|
3.7
± 0.3
|
3592 |
EN300-126127_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(C6CC6)O |
−5.0
± 0.2
|
3.7
± 0.2
|
3593 |
EN300-365965_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC6(C5)CS(=O)(=O)C6 |
−5.0
± 0.3
|
3.7
± 0.2
|
3594 |
EN300-08705_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNC(=O)C5 |
−5.0
± 0.3
|
3.7
± 0.2
|
3595 |
EN300-298807_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5[nH]c(=O)cc(n5)O |
−5.0
± 0.3
|
3.7
± 0.2
|
3596 |
EN300-93174_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(c5c[nH]c(=O)[nH]c5=O)(F)F |
−5.0
± 0.4
|
3.7
± 0.3
|
3597 |
JOH-SUS-a69c159d-1
|
|
Cc1c2ccccc2c(cn1)NC(=O)C3CCOc4c3cc(cc4)Cl |
−5.0
± 0.2
|
3.7
± 0.1
|
3598 |
EN300-124301_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCn5ccnn5 |
−5.0
± 0.2
|
3.7
± 0.2
|
3599 |
EN300-101197_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5[nH]cnn5 |
−5.0
± 0.3
|
3.7
± 0.2
|
3600 |
EN300-6474647_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN6C(C5)CCNC6=O |
−5.0
± 0.2
|
3.7
± 0.1
|