Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3401 |
EN300-127487_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(=O)NC5 |
−5.3
± 0.2
|
3.9
± 0.2
|
3402 |
EN300-298869_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCOC5)OCCO |
−5.3
± 0.3
|
3.9
± 0.2
|
3403 |
EN300-72896_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CCC(=O)N5 |
−5.3
± 0.2
|
3.9
± 0.1
|
3404 |
EN300-343474_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCNC5=O |
−5.3
± 0.3
|
3.9
± 0.2
|
3405 |
EN300-322494_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC56COCCN5CCOC6 |
−5.3
± 0.3
|
3.9
± 0.2
|
3406 |
EN300-6746631_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5nnc6n5CCCC6 |
−5.3
± 0.2
|
3.9
± 0.2
|
3407 |
MAK-UNK-8be7dca9-9
|
|
c1cc2c(cc1C(=O)O)cncc2NC(=O)C3CCOc4c3cc(cc4)Cl |
−5.3
± 0.1
|
3.89
± 0.07
|
3408 |
EN300-396748_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccnc(c5)CO |
−5.3
± 0.3
|
3.9
± 0.2
|
3409 |
EN300-84186_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)CO |
−5.3
± 0.4
|
3.9
± 0.3
|
3410 |
EN300-342082_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5ncncn5 |
−5.3
± 0.2
|
3.9
± 0.2
|
3411 |
EN300-6472847_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CN(C5)C(=O)N |
−5.3
± 0.2
|
3.9
± 0.2
|
3412 |
EN300-144935_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCN5CCCS5(=O)=O |
−5.3
± 0.2
|
3.9
± 0.2
|
3413 |
EN300-42819_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(=O)NC5 |
−5.3
± 0.2
|
3.9
± 0.2
|
3414 |
EN300-332002_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCc6n5c(=O)ccc6 |
−5.3
± 0.3
|
3.9
± 0.2
|
3415 |
EN300-75807_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCS(=O)(=O)CC5 |
−5.3
± 0.3
|
3.9
± 0.2
|
3416 |
EN300-682529_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCOC5)CO |
−5.3
± 0.2
|
3.9
± 0.2
|
3417 |
EN300-61021_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnc6n5cccn6 |
−5.3
± 0.4
|
3.9
± 0.3
|
3418 |
EN300-154700_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)(CO)CO |
−5.3
± 0.3
|
3.9
± 0.2
|
3419 |
EN300-6733995_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCNS(=O)(=O)C(F)F |
−5.3
± 0.4
|
3.9
± 0.3
|
3420 |
EN300-2009745_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(=O)NCC5C(=O)N |
−5.3
± 0.3
|
3.9
± 0.2
|
3421 |
EN300-68203_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCC(=O)N5 |
−5.3
± 0.2
|
3.9
± 0.1
|
3422 |
EN300-132141_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCc6c(nc[nH]c6=O)C5 |
−5.3
± 0.2
|
3.9
± 0.2
|
3423 |
EN300-323327_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccn6c(n5)ccn6 |
−5.3
± 0.3
|
3.9
± 0.2
|
3424 |
EN300-212797_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CN5CCCC5)CO |
−5.3
± 0.4
|
3.9
± 0.3
|
3425 |
EN300-10170_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(CO)NC(=O)N |
−5.3
± 0.3
|
3.9
± 0.3
|
3426 |
EN300-7430501_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCn6c(cnn6)C5 |
−5.3
± 0.2
|
3.9
± 0.1
|
3427 |
EN300-1215738_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCC5CCC(=O)NC5 |
−5.3
± 0.2
|
3.9
± 0.2
|
3428 |
EN300-67023_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CS(=O)(=O)CC5CCCO5 |
−5.3
± 0.4
|
3.9
± 0.3
|
3429 |
EN300-69852_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5C(=O)CNC5=O |
−5.3
± 0.2
|
3.9
± 0.1
|
3430 |
EN300-1725529_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCCO)C5COC5 |
−5.3
± 0.3
|
3.9
± 0.2
|
3431 |
EN300-14405_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6n(c5=O)CCS6 |
−5.3
± 0.3
|
3.9
± 0.3
|
3432 |
EN300-52210_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC6(CC5)CC(=O)N6 |
−5.3
± 0.2
|
3.9
± 0.2
|
3433 |
EN300-188341_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5ccc(cn5)O |
−5.3
± 0.3
|
3.9
± 0.2
|
3434 |
EN300-90531_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCCC5C(=O)N |
−5.3
± 0.3
|
3.9
± 0.2
|
3435 |
EN300-366857_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccn6c5ncn6 |
−5.3
± 0.3
|
3.9
± 0.2
|
3436 |
EN300-1720811_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC[C@H](CO)O |
−5.3
± 0.3
|
3.9
± 0.2
|
3437 |
EN300-91886_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(C5CC5)N6CCOCC6 |
−5.3
± 0.3
|
3.9
± 0.2
|
3438 |
EN300-139403_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H](CO)C(F)(F)F |
−5.3
± 0.4
|
3.9
± 0.3
|
3439 |
EN300-175160_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(C(F)F)O |
−5.3
± 0.2
|
3.9
± 0.1
|
3440 |
EN300-3451857_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCC(=O)NC5=O |
−5.3
± 0.2
|
3.9
± 0.2
|
3441 |
EN300-254554_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCS(=O)(=O)C5CC5 |
−5.3
± 0.6
|
3.9
± 0.4
|
3442 |
EN300-175400_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCn6c(cnn6)C5 |
−5.3
± 0.3
|
3.9
± 0.2
|
3443 |
EN300-106023_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(no5)C(=O)N |
−5.3
± 0.3
|
3.8
± 0.2
|
3444 |
EN300-250836_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5c[nH]nc5 |
−5.3
± 0.2
|
3.8
± 0.2
|
3445 |
EN300-309235_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(C5)CO |
−5.3
± 0.2
|
3.8
± 0.2
|
3446 |
EN300-1074262_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccn6c5cnn6 |
−5.3
± 0.3
|
3.8
± 0.2
|
3447 |
EN300-6474064_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)c6[nH]nnn6 |
−5.3
± 0.3
|
3.8
± 0.2
|
3448 |
EN300-341337_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C56CCOC5CCOC6 |
−5.3
± 0.2
|
3.8
± 0.2
|
3449 |
EN300-255990_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5ncc(c6)C#N |
−5.3
± 0.3
|
3.8
± 0.2
|
3450 |
EN300-2007648_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C56CC(C5)CO6 |
−5.3
± 0.2
|
3.8
± 0.2
|
3451 |
EN300-6745581_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5nncn5C6CC6 |
−5.3
± 0.2
|
3.8
± 0.2
|
3452 |
EN300-98802_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)OCC(=O)N |
−5.3
± 0.2
|
3.8
± 0.2
|
3453 |
EN300-748981_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCn6c5nnc6 |
−5.3
± 0.2
|
3.8
± 0.2
|
3454 |
EN300-6779469_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5C6C5CS(=O)(=O)C6 |
−5.3
± 0.2
|
3.8
± 0.1
|
3455 |
EN300-97055_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c(=O)[nH]ccn5 |
−5.3
± 0.2
|
3.8
± 0.2
|
3456 |
EN300-77408_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CN(CCO5)C6CC6 |
−5.3
± 0.1
|
3.84
± 0.09
|
3457 |
EN300-249086_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CC[C@@H](C5)C(=O)N |
−5.3
± 0.3
|
3.8
± 0.2
|
3458 |
EN300-743350_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC6(C5)CCNC6=O |
−5.3
± 0.3
|
3.8
± 0.2
|
3459 |
EN300-120255_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCCOC5)C(=O)N |
−5.3
± 0.3
|
3.8
± 0.2
|
3460 |
EN300-398631_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCS(=O)(=O)N5CCCC5 |
−5.3
± 0.7
|
3.8
± 0.5
|
3461 |
EN300-246486_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5coc(=O)[nH]5 |
−5.3
± 0.2
|
3.8
± 0.2
|
3462 |
EN300-1212491_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5CCS(=O)(=O)C5 |
−5.3
± 0.2
|
3.8
± 0.2
|
3463 |
EN300-95507_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(on5)CO |
−5.3
± 0.2
|
3.8
± 0.2
|
3464 |
EN300-1644703_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)O |
−5.3
± 0.2
|
3.8
± 0.2
|
3465 |
EN300-41518_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCOCC5 |
−5.3
± 0.3
|
3.8
± 0.2
|
3466 |
EN300-25986_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCn5cccn5 |
−5.3
± 0.3
|
3.8
± 0.2
|
3467 |
EN300-111006_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccncn5 |
−5.2
± 0.2
|
3.8
± 0.2
|
3468 |
EN300-189729_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CCO6 |
−5.2
± 0.2
|
3.8
± 0.2
|
3469 |
ALP-UNI-4b8a177c-1
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3c(ccc4O)Cl |
−5.2
± 0.1
|
3.82
± 0.10
|
3470 |
EN300-155176_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCCS5(=O)=O |
−5.2
± 0.3
|
3.8
± 0.2
|
3471 |
EN300-75464_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5c(=O)c6ccnn6cn5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3472 |
EN300-321960_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn6c(n5)COCC6 |
−5.2
± 0.3
|
3.8
± 0.2
|
3473 |
EN300-7354033_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C56CC(C5)S(=O)(=O)C6 |
−5.2
± 0.3
|
3.8
± 0.2
|
3474 |
EN300-54417_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)c5cccc(c5)O |
−5.2
± 0.2
|
3.8
± 0.2
|
3475 |
EN300-75342_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCn5ccnc5 |
−5.2
± 0.2
|
3.8
± 0.1
|
3476 |
EN300-1703015_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(=O)Nc5[nH]ccn5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3477 |
EN300-148321_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)C6CCOC6 |
−5.2
± 0.2
|
3.8
± 0.1
|
3478 |
EN300-155823_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(CC#N)O |
−5.2
± 0.3
|
3.8
± 0.2
|
3479 |
EN300-13489_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCN(CC5)C(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3480 |
EN300-257536_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(=O)[nH]c(=O)[nH]5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3481 |
EN300-213215_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)N6CCC(C6)O |
−5.2
± 0.2
|
3.8
± 0.1
|
3482 |
EN300-200699_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCOC5)O |
−5.2
± 0.2
|
3.8
± 0.1
|
3483 |
EN300-39504_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCS(=O)(=O)N |
−5.2
± 0.5
|
3.8
± 0.3
|
3484 |
EN300-303908_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@]6(C[C@H]6C5)O |
−5.2
± 0.3
|
3.8
± 0.2
|
3485 |
EN300-317867_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCNC(=O)C5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3486 |
EN300-90068_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5ccc(nc5)C(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3487 |
EN300-4293814_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CS(=O)(=O)CCO |
−5.2
± 0.5
|
3.8
± 0.3
|
3488 |
EN300-1272704_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CCO[C@@H]5c6[nH]cnn6 |
−5.2
± 0.3
|
3.8
± 0.2
|
3489 |
EN300-100741_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5[nH]cnn5 |
−5.2
± 0.2
|
3.8
± 0.2
|
3490 |
EN300-6743781_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCCNS(=O)(=O)CC5 |
−5.2
± 0.4
|
3.8
± 0.3
|
3491 |
EN300-21009_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCO5 |
−5.2
± 0.2
|
3.8
± 0.2
|
3492 |
EN300-658559_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)n6ccnn6 |
−5.2
± 0.3
|
3.8
± 0.2
|
3493 |
EN300-312662_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]c(nn5)CO |
−5.2
± 0.3
|
3.8
± 0.2
|
3494 |
EN300-33999_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5[nH]nnn5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3495 |
EN300-7355835_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCn6c(c(cn6)O)C5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3496 |
EN300-152756_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H](C[C@H]5CO)O |
−5.2
± 0.2
|
3.8
± 0.2
|
3497 |
EN300-77438_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCN(C5=O)C6CC6 |
−5.2
± 0.1
|
3.8
± 0.1
|
3498 |
EN300-246992_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCC(=O)NC5 |
−5.2
± 0.3
|
3.8
± 0.2
|
3499 |
EN300-31015_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCSCC(=O)N |
−5.2
± 0.3
|
3.8
± 0.2
|
3500 |
EN300-83280_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)c5ccccn5 |
−5.2
± 0.3
|
3.8
± 0.2
|