Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3301 |
EN300-87536_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5CCCN5C(=O)N |
−5.5
± 0.3
|
4.0
± 0.2
|
3302 |
EN300-14767_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCN(C5)C(=O)N |
−5.5
± 0.2
|
4.0
± 0.2
|
3303 |
EN300-131572_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnn6c5cncc6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3304 |
DAR-DIA-0d514e7d-22
|
|
C[C@H]1COc2c(cc(cc2N3CCN(CC3)C)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3305 |
VLA-UCB-34f3ed0c-19
|
|
c1ccc2c(c1)cncc2N(C(=O)c3ccco3)C(=O)[C@@H]4CCOc5c4cc(cc5)Cl |
−5.5
± 0.2
|
4.0
± 0.2
|
3306 |
EN300-313440_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CN(C5)C6CCOCC6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3307 |
EN300-1609922_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)(c6ccn[nH]6)O |
−5.5
± 0.4
|
4.0
± 0.3
|
3308 |
EN300-7444121_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]([C@H](C56CCC6)O)O |
−5.5
± 0.3
|
4.0
± 0.2
|
3309 |
EN300-226921_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCCN5CCCO |
−5.5
± 0.3
|
4.0
± 0.2
|
3310 |
EN300-268196_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)N6CCOCC6 |
−5.5
± 0.4
|
4.0
± 0.3
|
3311 |
EN300-383824_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6c([nH]c5=O)CCOC6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3312 |
EN300-267089_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5[C@@H](CC[C@H]5CO)CO |
−5.5
± 0.4
|
4.0
± 0.3
|
3313 |
EN300-159881_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCCOCC5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3314 |
EN300-69368_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCOCC5)O |
−5.5
± 0.3
|
4.0
± 0.2
|
3315 |
EN300-65063_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCN(CC5)C(=O)N |
−5.5
± 0.2
|
4.0
± 0.2
|
3316 |
EN300-7427198_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCN(C5)C6COC6 |
−5.5
± 0.2
|
4.0
± 0.1
|
3317 |
EN300-1696143_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CCCN6C(=O)C5 |
−5.5
± 0.2
|
4.0
± 0.2
|
3318 |
EN300-270328_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCn5cncn5 |
−5.5
± 0.1
|
4.0
± 0.1
|
3319 |
EN300-7442191_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CN6CCC5CC6)O |
−5.5
± 0.3
|
4.0
± 0.2
|
3320 |
EN300-1256657_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNC(=O)C5C6CC6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3321 |
EN300-6737762_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCCNC5=O |
−5.5
± 0.2
|
4.0
± 0.1
|
3322 |
EN300-298184_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCNC5=O |
−5.5
± 0.2
|
4.0
± 0.2
|
3323 |
EN300-203306_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)(C(=O)N)O |
−5.5
± 0.4
|
4.0
± 0.3
|
3324 |
EN300-105873_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5ccccc5=O |
−5.5
± 0.3
|
4.0
± 0.2
|
3325 |
EN300-188316_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(CO)C5CCOC5 |
−5.5
± 0.2
|
4.0
± 0.1
|
3326 |
EN300-123400_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(C5CCOC5)C(=O)N |
−5.5
± 0.2
|
4.0
± 0.1
|
3327 |
EN300-31244_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCS(=O)(=O)C5 |
−5.5
± 0.1
|
4.0
± 0.1
|
3328 |
EN300-755040_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCn5ccc(=O)[nH]c5=O |
−5.5
± 0.3
|
4.0
± 0.2
|
3329 |
EN300-367589_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(=O)NCC56COC6 |
−5.5
± 0.4
|
4.0
± 0.3
|
3330 |
EN300-195072_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CN(CCO5)C(=O)N |
−5.5
± 0.3
|
4.0
± 0.2
|
3331 |
EN300-248618_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CS(=O)(=O)C5CC5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3332 |
EN300-43206_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCCS5(=O)=O |
−5.5
± 0.4
|
4.0
± 0.3
|
3333 |
EN300-05620_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCNC(=O)N |
−5.4
± 0.3
|
4.0
± 0.2
|
3334 |
DAR-DIA-0d514e7d-10
|
|
C[C@H]1COc2c(cc(cc2Nc3cnn(c3)C)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−5.4
± 0.2
|
4.0
± 0.1
|
3335 |
EN300-1425963_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCC5N6CCOCC6 |
−5.4
± 0.2
|
4.0
± 0.1
|
3336 |
EN300-245318_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(C5)C(=O)C6CC6 |
−5.4
± 0.2
|
4.0
± 0.2
|
3337 |
EN300-62448_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CNC(=O)C5CCC5 |
−5.4
± 0.3
|
4.0
± 0.2
|
3338 |
EN300-1071940_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5(CCCOC5)O |
−5.4
± 0.2
|
4.0
± 0.1
|
3339 |
EN300-20980_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5cnnn5 |
−5.4
± 0.3
|
4.0
± 0.2
|
3340 |
EN300-19900_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnccn5 |
−5.4
± 0.2
|
4.0
± 0.2
|
3341 |
EN300-321558_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC(C5)CC(=O)N |
−5.4
± 0.2
|
4.0
± 0.2
|
3342 |
EN300-298807_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]c(=O)cc(n5)O |
−5.4
± 0.3
|
4.0
± 0.2
|
3343 |
EN300-106781_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5ccc(=O)[nH]c5=O |
−5.4
± 0.3
|
4.0
± 0.2
|
3344 |
EN300-192893_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccn6c(c5)ncn6 |
−5.4
± 0.3
|
4.0
± 0.2
|
3345 |
EN300-40048_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)CCC#N |
−5.4
± 0.4
|
4.0
± 0.3
|
3346 |
EN300-83864_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(CC5)S(=O)(=O)N |
−5.4
± 0.3
|
4.0
± 0.2
|
3347 |
EN300-249899_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6ncccn6cn5 |
−5.4
± 0.2
|
4.0
± 0.2
|
3348 |
EN300-118869_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)NC(=O)N |
−5.4
± 0.2
|
4.0
± 0.2
|
3349 |
EN300-6488240_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5nncs5 |
−5.4
± 0.2
|
4.0
± 0.2
|
3350 |
EN300-6489145_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNS(=O)(=O)CC5 |
−5.4
± 0.4
|
4.0
± 0.3
|
3351 |
EN300-193679_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCCOC5)O |
−5.4
± 0.3
|
4.0
± 0.2
|
3352 |
EN300-13287_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5ccc(=O)[nH]c5=O |
−5.4
± 0.3
|
4.0
± 0.2
|
3353 |
EN300-250112_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5csc(n5)CO |
−5.4
± 0.3
|
3.9
± 0.2
|
3354 |
EN300-309457_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CN(C5)C6CCOC6 |
−5.4
± 0.2
|
3.9
± 0.2
|
3355 |
EN300-7430372_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CNC(=O)CO6 |
−5.4
± 0.3
|
3.9
± 0.2
|
3356 |
EN300-233951_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC(C5)O |
−5.4
± 0.2
|
3.9
± 0.2
|
3357 |
EN300-259060_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(C5)(CC(=O)N)O |
−5.4
± 0.3
|
3.9
± 0.2
|
3358 |
EN300-39504_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCS(=O)(=O)N |
−5.4
± 0.4
|
3.9
± 0.3
|
3359 |
EN300-7534935_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CCC(=O)O6 |
−5.4
± 0.3
|
3.9
± 0.2
|
3360 |
EN300-1707774_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)OC(=O)N |
−5.4
± 0.2
|
3.9
± 0.2
|
3361 |
EN300-7442191_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CN6CCC5CC6)O |
−5.4
± 0.3
|
3.9
± 0.2
|
3362 |
EN300-343434_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCC5)c6[nH]nnn6 |
−5.4
± 0.3
|
3.9
± 0.2
|
3363 |
EN300-1718836_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5nnc6n5CCOC6 |
−5.4
± 0.3
|
3.9
± 0.2
|
3364 |
ADA-UCB-dc2b944c-13
|
|
C[C@@H]1COc2ccc(cc2[C@H]1C(=O)Nc3cncc4c3cccc4)Cl |
−5.4
± 0.2
|
3.9
± 0.1
|
3365 |
EN300-7435929_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ncc6c(n5)CCOC6 |
−5.4
± 0.2
|
3.9
± 0.2
|
3366 |
EN300-124555_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc6c(nc5)n[nH]n6 |
−5.4
± 0.3
|
3.9
± 0.2
|
3367 |
EN300-658865_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc([nH]n5)CO |
−5.4
± 0.3
|
3.9
± 0.2
|
3368 |
EN300-6760451_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5nnc6n5cccc6 |
−5.4
± 0.2
|
3.9
± 0.2
|
3369 |
EN300-202232_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(C(=O)C5)C6CC6 |
−5.4
± 0.2
|
3.9
± 0.1
|
3370 |
EN300-34531_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5ccc(s5)S(=O)(=O)N |
−5.4
± 0.3
|
3.9
± 0.2
|
3371 |
EN300-1072972_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCOC5=O |
−5.4
± 0.3
|
3.9
± 0.2
|
3372 |
EN300-36111_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCCC5=O |
−5.4
± 0.3
|
3.9
± 0.2
|
3373 |
EN300-317867_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCNC(=O)C5 |
−5.4
± 0.4
|
3.9
± 0.3
|
3374 |
EN300-237561_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5c(=O)cccn5 |
−5.4
± 0.3
|
3.9
± 0.2
|
3375 |
EN300-237561_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5c(=O)cccn5 |
−5.4
± 0.3
|
3.9
± 0.2
|
3376 |
EN300-185751_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cncnc5 |
−5.4
± 0.2
|
3.9
± 0.1
|
3377 |
EN300-83527_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc6ncccn6n5 |
−5.4
± 0.2
|
3.9
± 0.2
|
3378 |
EN300-7438227_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCC5)CCS(=O)(=O)N |
−5.4
± 0.5
|
3.9
± 0.4
|
3379 |
EN300-7494115_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6c(=O)[nH]cnc6nc5 |
−5.4
± 0.3
|
3.9
± 0.2
|
3380 |
EN300-7441080_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6cccn6c(=O)[nH]5 |
−5.4
± 0.2
|
3.9
± 0.2
|
3381 |
EN300-6740040_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCNS(=O)(=O)N |
−5.4
± 0.5
|
3.9
± 0.4
|
3382 |
EN300-212795_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC5CNC(=O)N |
−5.4
± 0.3
|
3.9
± 0.2
|
3383 |
EN300-1271967_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)C(=O)CCO |
−5.4
± 0.3
|
3.9
± 0.2
|
3384 |
EN300-7432415_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5C6(CCC6)OC(=O)N5 |
−5.4
± 0.3
|
3.9
± 0.2
|
3385 |
EN300-190253_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(cc(=O)o5)O |
−5.4
± 0.3
|
3.9
± 0.2
|
3386 |
EN300-1268512_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5ccsc5S(=O)(=O)N |
−5.4
± 0.3
|
3.9
± 0.3
|
3387 |
EN300-149224_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnc(cn5)C#N |
−5.4
± 0.3
|
3.9
± 0.2
|
3388 |
EN300-731622_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5COCCO5 |
−5.4
± 0.2
|
3.9
± 0.1
|
3389 |
EN300-88819_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c6c(on5)CCOC6 |
−5.4
± 0.3
|
3.9
± 0.2
|
3390 |
EN300-657211_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5[nH]c(nn5)C6CC6 |
−5.4
± 0.3
|
3.9
± 0.2
|
3391 |
EN300-657410_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)c5[nH]ccn5 |
−5.4
± 0.3
|
3.9
± 0.2
|
3392 |
EN300-100765_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN6C(C5)CNC6=O |
−5.4
± 0.2
|
3.9
± 0.1
|
3393 |
EN300-321161_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCN5CCOCC5 |
−5.4
± 0.2
|
3.9
± 0.2
|
3394 |
EN300-313360_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(C5CCCO5)O |
−5.4
± 0.3
|
3.9
± 0.2
|
3395 |
EN300-6491682_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCc6c(nn[nH]6)C5 |
−5.4
± 0.2
|
3.9
± 0.2
|
3396 |
EN300-43206_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCS5(=O)=O |
−5.3
± 0.3
|
3.9
± 0.2
|
3397 |
EN300-238405_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CC(=O)NC5 |
−5.3
± 0.3
|
3.9
± 0.2
|
3398 |
EN300-121144_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5ccccc5C(=O)N |
−5.3
± 0.2
|
3.9
± 0.2
|
3399 |
EN300-122590_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5nnc(s5)CCO |
−5.3
± 0.2
|
3.9
± 0.2
|
3400 |
EN300-54837_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5C(=O)CCCC5=O |
−5.3
± 0.2
|
3.9
± 0.2
|