Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3201 |
EN300-39506_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)NC5CCS(=O)(=O)C5 |
−5.6
± 0.4
|
4.1
± 0.3
|
3202 |
EN300-1073320_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(C5(CCC5)O)O |
−5.6
± 0.2
|
4.1
± 0.2
|
3203 |
EN300-92012_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5C(=O)CCCC5=O |
−5.6
± 0.3
|
4.1
± 0.2
|
3204 |
EN300-95642_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5c[nH]c(=O)[nH]c5=O |
−5.6
± 0.2
|
4.1
± 0.2
|
3205 |
EN300-38979_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5ccnc5 |
−5.6
± 0.2
|
4.1
± 0.1
|
3206 |
EN300-6474064_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)c6[nH]nnn6 |
−5.6
± 0.2
|
4.1
± 0.1
|
3207 |
EN300-176135_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnc6n5nccc6 |
−5.6
± 0.2
|
4.1
± 0.2
|
3208 |
EN300-262599_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H]6COC(=O)N[C@@H]6C5 |
−5.6
± 0.3
|
4.1
± 0.2
|
3209 |
EN300-379533_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)O |
−5.6
± 0.2
|
4.1
± 0.2
|
3210 |
EN300-1703415_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5COCCO5 |
−5.6
± 0.3
|
4.1
± 0.2
|
3211 |
EN300-43282_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC5c6[nH]nnn6 |
−5.6
± 0.2
|
4.1
± 0.2
|
3212 |
EN300-183736_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOC5)CCO |
−5.6
± 0.2
|
4.1
± 0.2
|
3213 |
EN300-1215738_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCC5CCC(=O)NC5 |
−5.6
± 0.3
|
4.1
± 0.2
|
3214 |
EN300-6763991_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5nnc6n5CCOC6 |
−5.6
± 0.3
|
4.1
± 0.2
|
3215 |
EN300-257949_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CC[C@H]5O |
−5.6
± 0.2
|
4.1
± 0.2
|
3216 |
EN300-1661036_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CC5)c6[nH]nnn6 |
−5.6
± 0.2
|
4.1
± 0.1
|
3217 |
EN300-75342_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5ccnc5 |
−5.6
± 0.2
|
4.1
± 0.2
|
3218 |
EN300-181558_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5(CCC(CC5)O)O |
−5.6
± 0.3
|
4.1
± 0.2
|
3219 |
EN300-93491_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnnn5C6CC6 |
−5.6
± 0.3
|
4.1
± 0.2
|
3220 |
EN300-225012_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c6nccn6ccn5 |
−5.6
± 0.2
|
4.1
± 0.1
|
3221 |
EN300-3044054_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCC(=O)N5C6CC6 |
−5.6
± 0.2
|
4.1
± 0.1
|
3222 |
VLA-UCB-05e51b3f-4
|
|
CC(=O)N(c1cncc2c1cccc2)C(=O)[C@H]3CCOc4c3cc(cc4)Cl |
−5.6
± 0.2
|
4.1
± 0.1
|
3223 |
EN300-14437_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCS(=O)(=O)C5 |
−5.6
± 0.2
|
4.1
± 0.1
|
3224 |
EN300-141224_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCn6c(ncn6)C5 |
−5.6
± 0.3
|
4.1
± 0.2
|
3225 |
EN300-107435_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCCS5(=O)=O |
−5.6
± 0.2
|
4.1
± 0.1
|
3226 |
EN300-1662365_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCc6ncnn6C5 |
−5.6
± 0.2
|
4.1
± 0.1
|
3227 |
EN300-1087098_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCC(C(=O)N5)(F)F |
−5.6
± 0.2
|
4.1
± 0.2
|
3228 |
EN300-260621_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5ccc(=O)[nH]c5 |
−5.6
± 0.3
|
4.1
± 0.2
|
3229 |
EN300-7538678_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(=O)n6c5COCC6 |
−5.6
± 0.3
|
4.1
± 0.2
|
3230 |
EN300-1179673_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cccc(c5)C(=O)N |
−5.6
± 0.3
|
4.1
± 0.2
|
3231 |
EN300-220676_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCCS(=O)(=O)C5 |
−5.6
± 0.2
|
4.1
± 0.2
|
3232 |
EN300-66461_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CNC(=O)N5 |
−5.6
± 0.2
|
4.1
± 0.1
|
3233 |
EN300-386232_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CC5CCCO5)CO |
−5.6
± 0.2
|
4.1
± 0.2
|
3234 |
EN300-301925_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCCOC5)C#N |
−5.6
± 0.2
|
4.1
± 0.2
|
3235 |
EN300-204239_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cc(=O)[nH]c(n5)C6CC6 |
−5.6
± 0.3
|
4.1
± 0.2
|
3236 |
EN300-1428769_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC[C@@H]5[C@H](CO)O |
−5.6
± 0.5
|
4.1
± 0.4
|
3237 |
EN300-1266316_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCS(=O)(=O)N5 |
−5.6
± 0.2
|
4.1
± 0.2
|
3238 |
EN300-6759972_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(CC5)NC(=O)N |
−5.6
± 0.2
|
4.1
± 0.2
|
3239 |
EN300-2007620_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(OCC5)CO |
−5.6
± 0.2
|
4.1
± 0.2
|
3240 |
EN300-640698_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc([nH]c5=O)C#N |
−5.6
± 0.3
|
4.1
± 0.2
|
3241 |
EN300-360157_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5(CCOC5)O |
−5.6
± 0.3
|
4.1
± 0.2
|
3242 |
EN300-657320_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5CSCC(=O)N5 |
−5.6
± 0.2
|
4.1
± 0.2
|
3243 |
EN300-99214_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(=O)N(C5)C6CC6 |
−5.6
± 0.2
|
4.1
± 0.2
|
3244 |
EN300-624143_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC56CC(C6)O |
−5.6
± 0.3
|
4.1
± 0.2
|
3245 |
EN300-1091448_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC5(CO)CO |
−5.6
± 0.3
|
4.1
± 0.2
|
3246 |
EN300-322100_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc6n5ncc6 |
−5.6
± 0.2
|
4.1
± 0.2
|
3247 |
EN300-1212400_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(CC5CO)CO |
−5.6
± 0.2
|
4.1
± 0.1
|
3248 |
EN300-184355_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(C(=O)N)O |
−5.6
± 0.4
|
4.1
± 0.3
|
3249 |
EN300-7434398_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CC5)c6[nH]cnn6 |
−5.6
± 0.3
|
4.1
± 0.2
|
3250 |
EN300-127156_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(no5)C(=O)N |
−5.6
± 0.2
|
4.0
± 0.2
|
3251 |
EN300-294602_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ccsc5S(=O)(=O)N |
−5.6
± 0.3
|
4.0
± 0.2
|
3252 |
EN300-304981_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5[nH]c(nn5)C6CCOC6 |
−5.6
± 0.2
|
4.0
± 0.2
|
3253 |
EN300-370767_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnc6n5cc[nH]c6=O |
−5.6
± 0.2
|
4.0
± 0.2
|
3254 |
EN300-1723511_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCC5)CO |
−5.5
± 0.3
|
4.0
± 0.2
|
3255 |
EN300-1718675_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnnn5C6CC6 |
−5.5
± 0.2
|
4.0
± 0.2
|
3256 |
EN300-1724075_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(CO)(CO)O |
−5.5
± 0.4
|
4.0
± 0.3
|
3257 |
EN300-6763900_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCCC56COC6 |
−5.5
± 0.4
|
4.0
± 0.3
|
3258 |
EN300-1719428_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5cc(cnc5)S(=O)(=O)N |
−5.5
± 0.2
|
4.0
± 0.2
|
3259 |
EN300-322332_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5ccc(nc5)C(=O)N |
−5.5
± 0.3
|
4.0
± 0.2
|
3260 |
EN300-257058_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5C[C@H]5N6CCOCC6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3261 |
EN300-44993_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(cnc5)C(=O)N |
−5.5
± 0.3
|
4.0
± 0.2
|
3262 |
EN300-378652_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CC5)S(=O)(=O)N |
−5.5
± 0.3
|
4.0
± 0.2
|
3263 |
EN300-396146_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(CO)CO |
−5.5
± 0.2
|
4.0
± 0.2
|
3264 |
EN300-57126_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(CN5CCCC5=O)O |
−5.5
± 0.4
|
4.0
± 0.3
|
3265 |
EN300-245265_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCn5cnc(n5)C#N |
−5.5
± 0.3
|
4.0
± 0.2
|
3266 |
EN300-6745997_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CC[C@@H]([C@H]([C@H]5O)O)O |
−5.5
± 0.3
|
4.0
± 0.2
|
3267 |
EN300-1440100_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC6(C5)CC(=O)NC6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3268 |
EN300-7430165_1
|
|
CS(=O)(=O)C[C@H]1C[C@H](C1)NC(=O)C[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3269 |
EN300-7373519_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c(c(=O)[nH]c(=O)[nH]6)C5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3270 |
EN300-75030_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCC(=O)N5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3271 |
EN300-301425_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)(CO)O |
−5.5
± 0.4
|
4.0
± 0.3
|
3272 |
EN300-321053_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCOCC5O |
−5.5
± 0.2
|
4.0
± 0.2
|
3273 |
EN300-107990_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)c5cccnc5 |
−5.5
± 0.2
|
4.0
± 0.2
|
3274 |
EN300-254272_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(=O)cc[nH]5 |
−5.5
± 0.2
|
4.0
± 0.2
|
3275 |
VLA-UCB-05e51b3f-9
|
|
c1ccc2c(c1)cncc2N(C(=O)CCl)C(=O)[C@H]3CCOc4c3cc(cc4)Cl |
−5.5
± 0.2
|
4.0
± 0.2
|
3276 |
EN300-39504_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCS(=O)(=O)N |
−5.5
± 0.4
|
4.0
± 0.3
|
3277 |
EN300-321459_2
|
|
CN(C(=O)CC[C@@]1(c2c(ccc(c2)Cl)OCC1)C(=O)Nc3c4c(cnc3)cccc4)[C@H]5C[C@H](C5)C(=O)N |
−5.5
± 0.3
|
4.0
± 0.2
|
3278 |
EN300-82181_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NCCO |
−5.5
± 0.3
|
4.0
± 0.2
|
3279 |
EN300-40888_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC(=O)N |
−5.5
± 0.3
|
4.0
± 0.2
|
3280 |
EN300-55109_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC5CO |
−5.5
± 0.2
|
4.0
± 0.1
|
3281 |
EN300-1605566_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CN6CCN5CC6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3282 |
MAK-UNK-8be7dca9-8
|
|
c1cc2cncc(c2cc1CC(=O)O)NC(=O)C3CCOc4c3cc(cc4)Cl |
−5.5
± 0.1
|
4.02
± 0.09
|
3283 |
EN300-251562_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6n5nccc6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3284 |
EN300-746646_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn6cc[nH]c(=O)c6n5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3285 |
EN300-172481_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)(C(=O)N)O |
−5.5
± 0.3
|
4.0
± 0.2
|
3286 |
JAG-UCB-706446eb-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)Cc5cccc(c5)CN |
−5.5
± 0.2
|
4.0
± 0.1
|
3287 |
EN300-252044_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5C[C@@H]5N6CCOCC6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3288 |
EN300-103638_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCOC5=O |
−5.5
± 0.3
|
4.0
± 0.2
|
3289 |
EN300-263408_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC5(CCOC5)O |
−5.5
± 0.2
|
4.0
± 0.2
|
3290 |
EN300-36089_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)c5ccncc5 |
−5.5
± 0.3
|
4.0
± 0.2
|
3291 |
EN300-186536_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCCCC5)n6cnnn6 |
−5.5
± 0.4
|
4.0
± 0.3
|
3292 |
EN300-53918_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCN5CCOC5=O |
−5.5
± 0.3
|
4.0
± 0.2
|
3293 |
EN300-133058_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccc6c(n5)n[nH]n6 |
−5.5
± 0.3
|
4.0
± 0.2
|
3294 |
EN300-7355777_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5ncc(s5)C(=O)N |
−5.5
± 0.2
|
4.0
± 0.2
|
3295 |
EN300-108422_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)CC(=O)N |
−5.5
± 0.2
|
4.0
± 0.2
|
3296 |
EN300-1605058_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC(=O)NC(=O)C5 |
−5.5
± 0.2
|
4.0
± 0.2
|
3297 |
EN300-186943_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCOCC5=O |
−5.5
± 0.2
|
4.0
± 0.2
|
3298 |
EN300-185751_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cncnc5 |
−5.5
± 0.1
|
4.0
± 0.1
|
3299 |
EN300-333078_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H](Cc5cnc[nH]5)CO |
−5.5
± 0.3
|
4.0
± 0.2
|
3300 |
EN300-1604607_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C56CC(C5)OC6 |
−5.5
± 0.2
|
4.0
± 0.2
|