Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2901 |
EN300-2690403_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(nc5)c6[nH]nnn6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2902 |
EN300-1661036_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CC5)c6[nH]nnn6 |
−6.0
± 0.2
|
4.4
± 0.1
|
2903 |
EN300-309106_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn6cnnc6cn5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2904 |
EN300-93174_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(c5c[nH]c(=O)[nH]c5=O)(F)F |
−6.0
± 0.6
|
4.4
± 0.4
|
2905 |
EN300-657320_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CSCC(=O)N5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2906 |
EN300-210084_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCCC(=O)N5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2907 |
EN300-6746631_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5nnc6n5CCCC6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2908 |
EN300-295372_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5ccnn5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2909 |
EN300-1271967_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)C(=O)CCO |
−6.0
± 0.4
|
4.4
± 0.3
|
2910 |
EN300-100916_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5nccn5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2911 |
EN300-77778_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCS(=O)(=O)C5 |
−6.0
± 0.2
|
4.3
± 0.2
|
2912 |
EN300-57990_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5[nH]nnn5 |
−6.0
± 0.2
|
4.3
± 0.2
|
2913 |
EN300-7500524_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@H]6[C@@H](C5)COC(=O)N6 |
−6.0
± 0.3
|
4.3
± 0.2
|
2914 |
EN300-43206_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCCS5(=O)=O |
−6.0
± 0.3
|
4.3
± 0.2
|
2915 |
EN300-86732_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCNC(=O)C5CCCO5 |
−6.0
± 0.2
|
4.3
± 0.2
|
2916 |
EN300-20363_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5nccnn5 |
−6.0
± 0.2
|
4.3
± 0.2
|
2917 |
EN300-6970573_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(COC5)CF |
−6.0
± 0.3
|
4.3
± 0.2
|
2918 |
EN300-1699492_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@H]5COCCO5 |
−6.0
± 0.3
|
4.3
± 0.2
|
2919 |
EN300-1724075_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(CO)(CO)O |
−6.0
± 0.4
|
4.3
± 0.3
|
2920 |
EN300-359750_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5CCC(=O)O5 |
−6.0
± 0.2
|
4.3
± 0.2
|
2921 |
EN300-109827_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN6C(C5)COC6=O |
−6.0
± 0.2
|
4.3
± 0.2
|
2922 |
EN300-6732363_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCNC(=O)N5CCOCC5 |
−6.0
± 0.3
|
4.3
± 0.2
|
2923 |
EN300-59043_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)Nc5c[nH]nc5 |
−6.0
± 0.3
|
4.3
± 0.2
|
2924 |
EN300-321161_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCN5CCOCC5 |
−6.0
± 0.2
|
4.3
± 0.2
|
2925 |
EN300-316171_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(C(=O)N)O |
−6.0
± 0.4
|
4.3
± 0.3
|
2926 |
EN300-98690_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnc6n5cccn6 |
−6.0
± 0.3
|
4.3
± 0.2
|
2927 |
EN300-105873_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCn5ccccc5=O |
−6.0
± 0.3
|
4.3
± 0.2
|
2928 |
EN300-129441_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc6n5ncn6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2929 |
EN300-135238_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5[nH]cc6 |
−5.9
± 0.2
|
4.3
± 0.2
|
2930 |
EN300-251752_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(Cn5ccnn5)O |
−5.9
± 0.2
|
4.3
± 0.2
|
2931 |
EN300-263085_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)n6cnnn6 |
−5.9
± 0.2
|
4.3
± 0.2
|
2932 |
EN300-243697_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CN(C5)C(=O)C(F)(F)F |
−5.9
± 0.2
|
4.3
± 0.2
|
2933 |
EN300-113234_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CC(=O)OC5 |
−5.9
± 0.2
|
4.3
± 0.1
|
2934 |
EN300-383904_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCNC(=O)CO |
−5.9
± 0.3
|
4.3
± 0.2
|
2935 |
EN300-1222185_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)C(=O)NC6CC6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2936 |
EN300-254121_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(c5cnc[nH]5)O |
−5.9
± 0.2
|
4.3
± 0.2
|
2937 |
EN300-343562_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC[C@H]([C@H]5CO)CO |
−5.9
± 0.3
|
4.3
± 0.2
|
2938 |
EN300-104029_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC6C(C5)C(=O)NC6=O |
−5.9
± 0.1
|
4.3
± 0.1
|
2939 |
EN300-05512_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NC5CCS(=O)(=O)C5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2940 |
EN300-6764893_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)OCCO |
−5.9
± 0.3
|
4.3
± 0.2
|
2941 |
EN300-105482_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(COC5)CO |
−5.9
± 0.2
|
4.3
± 0.2
|
2942 |
EN300-367383_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@]56C[C@H]5COC6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2943 |
EN300-323327_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ccn6c(n5)ccn6 |
−5.9
± 0.2
|
4.3
± 0.2
|
2944 |
EN300-731622_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5COCCO5 |
−5.9
± 0.2
|
4.3
± 0.1
|
2945 |
EN300-6491697_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCc5cccc(=O)[nH]5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2946 |
EN300-41375_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCCC5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2947 |
EN300-256583_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CS(=O)(=O)C5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2948 |
EN300-59043_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)Nc5c[nH]nc5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2949 |
EN300-7456641_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6c(nn5)CCOC6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2950 |
EN300-6474355_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CC(C5)C(F)F)C(=O)N |
−5.9
± 0.3
|
4.3
± 0.2
|
2951 |
EN300-58433_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc(c5)n6cncn6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2952 |
EN300-126408_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCN5CCS(=O)(=O)CC5 |
−5.9
± 0.4
|
4.3
± 0.3
|
2953 |
EN300-310888_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5nnc6n5CCOCC6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2954 |
EN300-365747_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)C(=O)N6CCOCC6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2955 |
EN300-366857_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccn6c5ncn6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2956 |
EN300-1228556_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)Cn6ccnn6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2957 |
EN300-6735568_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCc6nncn6C5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2958 |
EN300-2010167_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc6n5nnc6 |
−5.9
± 0.2
|
4.3
± 0.2
|
2959 |
EN300-36622_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5ccccc5=O |
−5.9
± 0.3
|
4.3
± 0.2
|
2960 |
EN300-225012_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6nccn6ccn5 |
−5.9
± 0.2
|
4.3
± 0.1
|
2961 |
DAR-DIA-0d514e7d-21
|
|
C[C@H]1COc2c(cc(cc2N3CCNCC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2962 |
EN300-246992_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCC(=O)NC5 |
−5.9
± 0.2
|
4.3
± 0.1
|
2963 |
EN300-6730698_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)N6CC(C6)O |
−5.9
± 0.2
|
4.3
± 0.2
|
2964 |
EN300-215014_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5(CCCOC5)O |
−5.9
± 0.2
|
4.3
± 0.2
|
2965 |
EN300-6746727_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5Cc6c([nH]c(=O)[nH]c6=O)C5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2966 |
EN300-196614_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCc5[nH]cnn5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2967 |
EN300-6735421_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5(CN(C5)C6CC6)CO |
−5.9
± 0.3
|
4.3
± 0.3
|
2968 |
EN300-6474355_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CC(C5)C(F)F)C(=O)N |
−5.9
± 0.3
|
4.3
± 0.2
|
2969 |
EN300-53918_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCN5CCOC5=O |
−5.9
± 0.4
|
4.3
± 0.3
|
2970 |
EN300-58864_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(nc5)C(=O)N |
−5.9
± 0.2
|
4.3
± 0.2
|
2971 |
EN300-6729573_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCN5CCNC5=O |
−5.9
± 0.3
|
4.3
± 0.2
|
2972 |
EN300-96544_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5[nH]c(=O)[nH]n5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2973 |
EN300-62449_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCNC(=O)C5CCC5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2974 |
EN300-1440321_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCC5)S(=O)(=O)N |
−5.9
± 0.3
|
4.3
± 0.2
|
2975 |
EN300-6526669_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnn6c5C(=O)NCC6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2976 |
EN300-52212_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCCN(C5)CC(=O)N |
−5.9
± 0.3
|
4.3
± 0.2
|
2977 |
EN300-22245_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccon5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2978 |
EN300-702062_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCOC5CCOC5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2979 |
EN300-54837_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5C(=O)CCCC5=O |
−5.9
± 0.2
|
4.3
± 0.2
|
2980 |
EN300-1726277_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(n5cccn5)F |
−5.9
± 0.2
|
4.3
± 0.1
|
2981 |
EN300-115421_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)c5c(cccn5)O |
−5.9
± 0.3
|
4.3
± 0.2
|
2982 |
EN300-1387104_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCS5(=O)=O |
−5.9
± 0.2
|
4.3
± 0.2
|
2983 |
EN300-103284_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCC5)CC(=O)N |
−5.9
± 0.2
|
4.3
± 0.2
|
2984 |
EN300-261859_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c(=O)[nH]sn5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2985 |
EN300-101637_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5nnco5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2986 |
EN300-264685_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)N6CCOCC6 |
−5.9
± 0.3
|
4.3
± 0.2
|
2987 |
EN300-1248250_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CN(C5)C(=O)N |
−5.9
± 0.3
|
4.3
± 0.2
|
2988 |
EN300-68350_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCOCC5)CO |
−5.9
± 0.3
|
4.3
± 0.3
|
2989 |
EN300-1072972_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCOC5=O |
−5.9
± 0.2
|
4.3
± 0.2
|
2990 |
EN300-13499_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCCNC(=O)N |
−5.9
± 0.3
|
4.3
± 0.2
|
2991 |
EN300-150212_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(n[nH]5)F |
−5.9
± 0.2
|
4.3
± 0.2
|
2992 |
EN300-260696_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(C5n6cccn6)O |
−5.9
± 0.2
|
4.3
± 0.1
|
2993 |
EN300-7465386_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCS(=O)(=O)C5)CO |
−5.9
± 0.3
|
4.3
± 0.2
|
2994 |
EN300-127612_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCNC(=O)c5ccn[nH]5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2995 |
EN300-171605_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5CS(=O)(=O)C5 |
−5.9
± 0.3
|
4.3
± 0.2
|
2996 |
EN300-393121_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6c(=O)[nH]ccn6n5 |
−5.9
± 0.2
|
4.3
± 0.2
|
2997 |
EN300-93878_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCN5CC[C@H](C5)O |
−5.9
± 0.2
|
4.3
± 0.1
|
2998 |
EN300-7355519_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CC6C(O5)CCO6 |
−5.9
± 0.1
|
4.27
± 0.09
|
2999 |
EN300-68618_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cocn5 |
−5.9
± 0.3
|
4.3
± 0.2
|
3000 |
EN300-6734276_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H]6[C@@]5(COC6=O)CO |
−5.9
± 0.3
|
4.3
± 0.2
|