Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2801 |
EN300-367292_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6C5CCCN6CCO |
−6.1
± 0.2
|
4.4
± 0.2
|
2802 |
EN300-373903_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)Cc6[nH]nnn6 |
−6.1
± 0.4
|
4.4
± 0.3
|
2803 |
EN300-294602_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccsc5S(=O)(=O)N |
−6.1
± 0.3
|
4.4
± 0.2
|
2804 |
EN300-210089_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5C6C5COC6 |
−6.1
± 0.1
|
4.4
± 0.1
|
2805 |
EN300-110244_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCOCO5 |
−6.1
± 0.2
|
4.4
± 0.1
|
2806 |
EN300-3710141_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCCO5)C#N |
−6.1
± 0.2
|
4.4
± 0.2
|
2807 |
EN300-98447_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CC(=O)N)C5CCOCC5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2808 |
EN300-366687_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCc6nncn6CC5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2809 |
EN300-83529_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5nc6ncccn6n5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2810 |
EN300-105267_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)Nc5cnccn5 |
−6.1
± 0.3
|
4.4
± 0.2
|
2811 |
EN300-38979_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5ccnc5 |
−6.1
± 0.2
|
4.4
± 0.1
|
2812 |
EN300-97758_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCF |
−6.1
± 0.2
|
4.4
± 0.1
|
2813 |
EN300-708742_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(=O)NC5=O |
−6.1
± 0.2
|
4.4
± 0.2
|
2814 |
EN300-2009339_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CS(=O)(=O)C56CCOCC6 |
−6.1
± 0.3
|
4.4
± 0.2
|
2815 |
EN300-6760451_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5nnc6n5cccc6 |
−6.1
± 0.2
|
4.4
± 0.2
|
2816 |
EN300-2913619_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5Cc6nccn6C5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2817 |
EN300-315963_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cnoc5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2818 |
EN300-139268_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(=O)NCC(F)(F)F |
−6.1
± 0.2
|
4.4
± 0.2
|
2819 |
EN300-246423_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5(CCC5)O |
−6.1
± 0.3
|
4.4
± 0.2
|
2820 |
EN300-6504535_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CC(CO5)CO |
−6.1
± 0.2
|
4.4
± 0.1
|
2821 |
EN300-128277_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(=O)NCC(F)F |
−6.1
± 0.3
|
4.4
± 0.2
|
2822 |
EN300-128464_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC(=O)NC5CC5 |
−6.1
± 0.3
|
4.4
± 0.2
|
2823 |
EN300-298582_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC5CC(=O)NC5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2824 |
EN300-99214_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC(=O)N(C5)C6CC6 |
−6.1
± 0.2
|
4.4
± 0.2
|
2825 |
EN300-111863_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5cnc(n5)C#N |
−6.1
± 0.3
|
4.4
± 0.2
|
2826 |
VLA-UCB-34f3ed0c-20
|
|
c1ccc2c(c1)cncc2N(C(=O)c3c[nH]cn3)C(=O)[C@@H]4CCOc5c4cc(cc5)Cl |
−6.1
± 0.3
|
4.4
± 0.2
|
2827 |
EN300-45049_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCS(=O)(=O)N5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2828 |
EN300-104493_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)C5CCOC5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2829 |
EN300-6499719_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccn6ccnc6n5 |
−6.1
± 0.3
|
4.4
± 0.2
|
2830 |
EN300-205779_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5CCC(=O)N5 |
−6.1
± 0.2
|
4.4
± 0.1
|
2831 |
EN300-1251424_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccn(n5)CC#N |
−6.1
± 0.2
|
4.4
± 0.2
|
2832 |
EN300-247428_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cn(nn5)CC6CC6 |
−6.1
± 0.2
|
4.4
± 0.2
|
2833 |
EN300-249899_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c6ncccn6cn5 |
−6.1
± 0.3
|
4.4
± 0.2
|
2834 |
EN300-1605566_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CN6CCN5CC6 |
−6.1
± 0.2
|
4.4
± 0.1
|
2835 |
EN300-52380_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn(nn5)CC(=O)N |
−6.0
± 0.3
|
4.4
± 0.2
|
2836 |
EN300-194172_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)CC(=O)N |
−6.0
± 0.3
|
4.4
± 0.2
|
2837 |
EN300-108506_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc(cn5)n6cccn6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2838 |
EN300-195590_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCCNC(=O)C5 |
−6.0
± 0.2
|
4.4
± 0.1
|
2839 |
EN300-19392_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCO |
−6.0
± 0.3
|
4.4
± 0.2
|
2840 |
EN300-222620_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cc(cnc5)O |
−6.0
± 0.3
|
4.4
± 0.2
|
2841 |
EN300-50674_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCN5CCOCC5)CCO |
−6.0
± 0.5
|
4.4
± 0.3
|
2842 |
EN300-6488157_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc6n5cnn6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2843 |
EN300-50194_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5cccn5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2844 |
EN300-60164_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CCCS5(=O)=O |
−6.0
± 0.2
|
4.4
± 0.2
|
2845 |
EN300-658355_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CCNC(=O)O6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2846 |
EN300-34636_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc(=O)[nH]5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2847 |
EN300-367405_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)n6ccnn6 |
−6.0
± 0.2
|
4.4
± 0.1
|
2848 |
EN300-303519_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5OCC6 |
−6.0
± 0.2
|
4.4
± 0.2
|
2849 |
EN300-80083_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCCC(=O)N5 |
−6.0
± 0.2
|
4.4
± 0.1
|
2850 |
EN300-300825_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCOCC5)CCO |
−6.0
± 0.2
|
4.4
± 0.2
|
2851 |
EN300-300519_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5csnn5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2852 |
EN300-396372_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CC(CNC6=O)O |
−6.0
± 0.2
|
4.4
± 0.2
|
2853 |
EN300-7540875_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6ncnn6c5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2854 |
EN300-101291_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(c(=O)[nH]c5=O)CCO |
−6.0
± 0.3
|
4.4
± 0.3
|
2855 |
EN300-259849_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCCC(C5=O)O |
−6.0
± 0.2
|
4.4
± 0.2
|
2856 |
EN300-58400_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccc(=O)n(c5)CC(=O)N |
−6.0
± 0.3
|
4.4
± 0.2
|
2857 |
EN300-304263_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(C(C5)C(=O)N)C6CC6 |
−6.0
± 0.2
|
4.4
± 0.2
|
2858 |
EN300-14006_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCS(=O)(=O)C5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2859 |
EN300-35248_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5ccc(cc5)S(=O)(=O)N |
−6.0
± 0.2
|
4.4
± 0.2
|
2860 |
EN300-316216_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCn5cncn5 |
−6.0
± 0.2
|
4.4
± 0.1
|
2861 |
EN300-70092_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)C(=O)N |
−6.0
± 0.3
|
4.4
± 0.2
|
2862 |
EN300-4726186_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CN5CCCNS5(=O)=O |
−6.0
± 0.3
|
4.4
± 0.2
|
2863 |
EN300-77265_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5cc(=O)c(co5)O |
−6.0
± 0.3
|
4.4
± 0.2
|
2864 |
EN300-214800_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCN5CCNC5=O |
−6.0
± 0.2
|
4.4
± 0.2
|
2865 |
EN300-246440_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)n6cncn6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2866 |
EN300-103979_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6c(nc5)OCC(=O)N6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2867 |
EN300-35789_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5cccnc5=O |
−6.0
± 0.2
|
4.4
± 0.2
|
2868 |
EN300-268196_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CC5)N6CCOCC6 |
−6.0
± 0.2
|
4.4
± 0.2
|
2869 |
EN300-41307_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5cnn(c5)CC(=O)N |
−6.0
± 0.2
|
4.4
± 0.2
|
2870 |
EN300-173536_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCS5(=O)=O |
−6.0
± 0.3
|
4.4
± 0.2
|
2871 |
EN300-114134_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCN5CCCS5(=O)=O |
−6.0
± 0.3
|
4.4
± 0.2
|
2872 |
EN300-378316_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5nnc6n5cc[nH]c6=O |
−6.0
± 0.3
|
4.4
± 0.2
|
2873 |
EN300-313360_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(C5CCCO5)O |
−6.0
± 0.5
|
4.4
± 0.3
|
2874 |
EN300-6504325_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCNS(=O)(=O)N |
−6.0
± 0.6
|
4.4
± 0.5
|
2875 |
EN300-99899_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)c5cccnn5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2876 |
EN300-182084_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CNC(=O)c5cscn5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2877 |
EN300-91886_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C5CC5)N6CCOCC6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2878 |
EN300-30039_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(=O)[nH]c(=O)[nH]5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2879 |
EN300-1589101_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5c[nH]nc5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2880 |
EN300-122866_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCSCC5C(=O)N |
−6.0
± 0.3
|
4.4
± 0.2
|
2881 |
DAR-DIA-23e5a6a0-10
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4CC5CC6(N5)CC6)Cl |
−6.0
± 0.2
|
4.4
± 0.2
|
2882 |
EN300-10334_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C56CCC(=O)N5CCS6 |
−6.0
± 0.2
|
4.4
± 0.1
|
2883 |
EN300-269419_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCNC(=O)N |
−6.0
± 0.2
|
4.4
± 0.1
|
2884 |
EN300-6730275_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCNS(=O)(=O)C5CC5 |
−6.0
± 0.4
|
4.4
± 0.3
|
2885 |
EN300-1720784_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC[C@@H](CO)O |
−6.0
± 0.3
|
4.4
± 0.2
|
2886 |
EN300-189672_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5ccc(=O)[nH]c5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2887 |
EN300-152337_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCC(=O)NCC5 |
−6.0
± 0.2
|
4.4
± 0.1
|
2888 |
EN300-1707870_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)(CCO)CO |
−6.0
± 0.2
|
4.4
± 0.1
|
2889 |
EN300-175474_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c(c(=O)[nH]cn6)C5 |
−6.0
± 0.2
|
4.4
± 0.2
|
2890 |
EN300-266552_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)c6[nH]cnn6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2891 |
EN300-64686_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5[nH]ccc(=O)n5 |
−6.0
± 0.2
|
4.4
± 0.1
|
2892 |
EN300-25960_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCCC5)O |
−6.0
± 0.3
|
4.4
± 0.2
|
2893 |
EN300-1273016_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCc6n5ncn6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2894 |
EN300-7432415_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5C6(CCC6)OC(=O)N5 |
−6.0
± 0.2
|
4.4
± 0.1
|
2895 |
EN300-248618_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CS(=O)(=O)C5CC5 |
−6.0
± 0.3
|
4.4
± 0.2
|
2896 |
EN300-11934_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCC5=O |
−6.0
± 0.3
|
4.4
± 0.2
|
2897 |
EN300-107892_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(nn5)C6CC6 |
−6.0
± 0.3
|
4.4
± 0.2
|
2898 |
ADA-UCB-dc2b944c-8
|
|
c1cc2c(cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl)c(c1)Cl |
−5.98
± 0.07
|
4.36
± 0.05
|
2899 |
EN300-227055_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CC(=O)NC5=O |
−6.0
± 0.2
|
4.4
± 0.1
|
2900 |
EN300-103284_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCC5)CC(=O)N |
−6.0
± 0.3
|
4.4
± 0.2
|