Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2701 |
EN300-6478631_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCc6n5cnn6 |
−6.2
± 0.2
|
4.5
± 0.2
|
2702 |
EN300-70656_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCC5)O |
−6.2
± 0.3
|
4.5
± 0.2
|
2703 |
EN300-112454_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccc(nn5)C(=O)N |
−6.2
± 0.2
|
4.5
± 0.2
|
2704 |
DAR-DIA-0d514e7d-23
|
|
C[C@H]1COc2c(cc(cc2N3CCCC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−6.2
± 0.2
|
4.5
± 0.1
|
2705 |
EN300-31998_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c[nH]nn5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2706 |
EN300-243828_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnncc5O |
−6.2
± 0.3
|
4.5
± 0.2
|
2707 |
EN300-103722_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnn6c5OCCC6 |
−6.2
± 0.3
|
4.5
± 0.2
|
2708 |
EN300-59705_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)NCc5ccncc5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2709 |
EN300-6736649_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CC(CO5)CC(=O)N |
−6.2
± 0.2
|
4.5
± 0.1
|
2710 |
EN300-7434398_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CC5)c6[nH]cnn6 |
−6.2
± 0.2
|
4.5
± 0.2
|
2711 |
EN300-131132_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5c[nH]nn5 |
−6.2
± 0.2
|
4.5
± 0.1
|
2712 |
EN300-149224_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnc(cn5)C#N |
−6.2
± 0.2
|
4.5
± 0.2
|
2713 |
EN300-149013_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c([nH]nn5)Cl |
−6.2
± 0.2
|
4.5
± 0.2
|
2714 |
EN300-34531_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5ccc(s5)S(=O)(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2715 |
EN300-100916_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5nccn5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2716 |
EN300-195072_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CN(CCO5)C(=O)N |
−6.2
± 0.2
|
4.5
± 0.1
|
2717 |
EN300-1704113_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)N5CC=CC5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2718 |
EN300-90142_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCC(C5)C(=O)N |
−6.2
± 0.2
|
4.5
± 0.1
|
2719 |
EN300-253365_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC(=O)Nc5[nH]ccn5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2720 |
EN300-94856_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CC(C5)O |
−6.2
± 0.3
|
4.5
± 0.2
|
2721 |
EN300-05512_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NC5CCS(=O)(=O)C5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2722 |
EN300-05277_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCC(=O)N5CCOCC5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2723 |
DAR-DIA-6a508060-8
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3cc(cc4)C5CC5 |
−6.2
± 0.1
|
4.50
± 0.09
|
2724 |
EN300-7448078_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC6(CC5)C(CC6O)O |
−6.2
± 0.2
|
4.5
± 0.1
|
2725 |
EN300-373446_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCO[C@@H](C5)[C@H](CO)O |
−6.2
± 0.5
|
4.5
± 0.3
|
2726 |
EN300-236974_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)S(=O)(=O)C6CC6 |
−6.2
± 0.3
|
4.5
± 0.2
|
2727 |
MAK-UNK-8be7dca9-3
|
|
c1ccc2c(c1)cncc2NC(=O)C3c4cc(ccc4OCC3CN)Cl |
−6.17
± 0.09
|
4.50
± 0.07
|
2728 |
EN300-44993_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cc(cnc5)C(=O)N |
−6.2
± 0.2
|
4.5
± 0.2
|
2729 |
EN300-131051_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc(ccn5)C(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2730 |
EN300-175220_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5cn[nH]c5C(=O)N |
−6.2
± 0.2
|
4.5
± 0.2
|
2731 |
EN300-182084_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)c5cscn5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2732 |
DAR-DIA-0d514e7d-2
|
|
C[C@@H]1COc2c(cc(cc2OC)Cl)[C@@H]1C(=O)Nc3cncc4c3cccc4 |
−6.2
± 0.1
|
4.49
± 0.08
|
2733 |
EN300-307418_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CC5(C6)C(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2734 |
EN300-24419_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5c(ccs5)S(=O)(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2735 |
EN300-09239_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc(c5)n6cnnn6 |
−6.2
± 0.3
|
4.5
± 0.2
|
2736 |
EN300-6746627_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5[nH]c(nn5)C(C6CC6)O |
−6.2
± 0.2
|
4.5
± 0.2
|
2737 |
EN300-191114_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCn5cccnc5=O |
−6.2
± 0.3
|
4.5
± 0.2
|
2738 |
EN300-51350_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCc6nncn6C5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2739 |
EN300-19900_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnccn5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2740 |
EN300-1723565_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CC5CCOC5)CO |
−6.2
± 0.3
|
4.5
± 0.2
|
2741 |
EN300-79588_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCCS(=O)(=O)N |
−6.2
± 0.2
|
4.5
± 0.2
|
2742 |
EN300-210256_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)CNC(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2743 |
EN300-157158_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC=CCO |
−6.2
± 0.2
|
4.5
± 0.1
|
2744 |
EN300-178829_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC(=O)NCC5CC5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2745 |
EN300-01527_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NCC5CCCO5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2746 |
EN300-75402_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCN(C5)C(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2747 |
EN300-04520_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cccc(c5)S(=O)(=O)N |
−6.1
± 0.3
|
4.5
± 0.2
|
2748 |
EN300-60514_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(cn5)S(=O)(=O)N |
−6.1
± 0.4
|
4.5
± 0.3
|
2749 |
EN300-20284_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(C5)O |
−6.1
± 0.3
|
4.5
± 0.2
|
2750 |
EN300-103722_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5OCCC6 |
−6.1
± 0.2
|
4.5
± 0.2
|
2751 |
EN300-262540_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccc(=O)n(c5)CCO |
−6.1
± 0.3
|
4.5
± 0.2
|
2752 |
EN300-245231_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCS(=O)(=O)CC5C6CC6 |
−6.1
± 0.3
|
4.5
± 0.2
|
2753 |
EN300-318344_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ncco5 |
−6.1
± 0.1
|
4.5
± 0.1
|
2754 |
EN300-263408_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5(CCOC5)O |
−6.1
± 0.2
|
4.5
± 0.2
|
2755 |
EN300-78135_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(=O)NC5CC5 |
−6.1
± 0.2
|
4.5
± 0.2
|
2756 |
EN300-6478054_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC(C5)CO |
−6.1
± 0.3
|
4.5
± 0.2
|
2757 |
EN300-187385_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCc5ccc(=O)[nH]c5 |
−6.1
± 0.3
|
4.5
± 0.2
|
2758 |
EN300-223187_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5c6c(nn5)CCCC6 |
−6.1
± 0.3
|
4.5
± 0.2
|
2759 |
EN300-1932780_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(C(F)F)O |
−6.1
± 0.2
|
4.5
± 0.2
|
2760 |
EN300-1720811_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC[C@H](CO)O |
−6.1
± 0.3
|
4.5
± 0.2
|
2761 |
EN300-42154_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CS(=O)(=O)C5CCCC5 |
−6.1
± 0.3
|
4.5
± 0.2
|
2762 |
EN300-261178_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5[nH]c(=O)ccn5 |
−6.1
± 0.2
|
4.5
± 0.2
|
2763 |
EN300-126866_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)N5CCOCC5 |
−6.1
± 0.3
|
4.5
± 0.2
|
2764 |
EN300-379616_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnc6n5CCNC6=O |
−6.1
± 0.3
|
4.5
± 0.2
|
2765 |
EN300-62448_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)C5CCC5 |
−6.1
± 0.3
|
4.5
± 0.2
|
2766 |
EN300-1264911_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(CF)O |
−6.1
± 0.3
|
4.5
± 0.2
|
2767 |
EN300-124374_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(cn5)S(=O)(=O)N |
−6.1
± 0.2
|
4.5
± 0.2
|
2768 |
EN300-309457_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CN(C5)C6CCOC6 |
−6.1
± 0.2
|
4.5
± 0.2
|
2769 |
EN300-107435_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCCS5(=O)=O |
−6.1
± 0.3
|
4.5
± 0.2
|
2770 |
EN300-6499719_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccn6ccnc6n5 |
−6.1
± 0.2
|
4.5
± 0.2
|
2771 |
EN300-61592_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCC[C@@H]5O |
−6.1
± 0.2
|
4.5
± 0.2
|
2772 |
EN300-6745997_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CC[C@@H]([C@H]([C@H]5O)O)O |
−6.1
± 0.3
|
4.5
± 0.2
|
2773 |
EN300-04520_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc(c5)S(=O)(=O)N |
−6.1
± 0.3
|
4.5
± 0.2
|
2774 |
EN300-7440263_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCn6c(ncn6)C5 |
−6.1
± 0.2
|
4.5
± 0.2
|
2775 |
EN300-210553_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(C5)(C(=O)N)O |
−6.1
± 0.2
|
4.5
± 0.1
|
2776 |
EN300-1270299_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(cn5)CO |
−6.1
± 0.2
|
4.5
± 0.2
|
2777 |
EN300-143449_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCN(=O)=O |
−6.1
± 0.2
|
4.5
± 0.2
|
2778 |
EN300-321597_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CC[C@H](C5)O |
−6.1
± 0.2
|
4.5
± 0.2
|
2779 |
EN300-42270_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnsn5 |
−6.1
± 0.2
|
4.5
± 0.2
|
2780 |
EN300-1709213_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC(C5)c6[nH]cnn6 |
−6.1
± 0.2
|
4.4
± 0.2
|
2781 |
EN300-101373_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC(C5)CO |
−6.1
± 0.2
|
4.4
± 0.2
|
2782 |
EN300-7463176_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5c(=O)[nH]cc6 |
−6.1
± 0.2
|
4.4
± 0.2
|
2783 |
EN300-708742_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC(=O)NC5=O |
−6.1
± 0.2
|
4.4
± 0.1
|
2784 |
EN300-06654_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cncn5 |
−6.1
± 0.2
|
4.4
± 0.1
|
2785 |
EN300-1068231_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn6ccncc6n5 |
−6.1
± 0.3
|
4.4
± 0.2
|
2786 |
EN300-303598_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nc(cs5)C(=O)N |
−6.1
± 0.2
|
4.4
± 0.2
|
2787 |
EN300-2910941_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(nn5)C(F)(F)F |
−6.1
± 0.2
|
4.4
± 0.2
|
2788 |
EN300-74089_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCOCC5)C#N |
−6.1
± 0.3
|
4.4
± 0.2
|
2789 |
EN300-80230_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ncccn5 |
−6.1
± 0.2
|
4.4
± 0.1
|
2790 |
EN300-17045_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5[nH]cnn5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2791 |
EN300-343433_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5c[nH]c(=O)nc5 |
−6.1
± 0.3
|
4.4
± 0.2
|
2792 |
EN300-91886_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(C5CC5)N6CCOCC6 |
−6.1
± 0.2
|
4.4
± 0.2
|
2793 |
EN300-210104_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5cnc(n5)C#N |
−6.1
± 0.2
|
4.4
± 0.2
|
2794 |
EN300-7465925_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC5CCNC(=O)C5 |
−6.1
± 0.3
|
4.4
± 0.2
|
2795 |
EN300-7385329_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5Cc6nccn6C5 |
−6.1
± 0.2
|
4.4
± 0.1
|
2796 |
EN300-220676_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCCS(=O)(=O)C5 |
−6.1
± 0.2
|
4.4
± 0.2
|
2797 |
EN300-7445890_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC6(C5)C(CC6O)O |
−6.1
± 0.3
|
4.4
± 0.2
|
2798 |
EN300-135123_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5ccc(cc5)C(=O)N |
−6.1
± 0.2
|
4.4
± 0.2
|
2799 |
EN300-1260794_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCSC5)CO |
−6.1
± 0.3
|
4.4
± 0.2
|
2800 |
EN300-83527_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6ncccn6n5 |
−6.1
± 0.2
|
4.4
± 0.2
|