Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2601 |
EN300-7456948_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cccnn5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2602 |
EN300-342226_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cnc[nH]5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2603 |
EN300-22473_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCn5ccnc5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2604 |
EN300-1248250_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CN(C5)C(=O)N |
−6.3
± 0.2
|
4.6
± 0.2
|
2605 |
EN300-99653_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCOCC5)CC(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2606 |
EN300-58259_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)NCC(F)(F)F |
−6.3
± 0.2
|
4.6
± 0.1
|
2607 |
VLA-UCB-50c39ae8-10
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC5CCCCC5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2608 |
EN300-7444335_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCOC5)c6[nH]nnn6 |
−6.3
± 0.2
|
4.6
± 0.1
|
2609 |
EN300-220527_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5[nH]ccn5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2610 |
EN300-260405_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)N6CCC(C6)O |
−6.3
± 0.2
|
4.6
± 0.1
|
2611 |
EN300-7121836_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn[nH]c5F |
−6.3
± 0.2
|
4.6
± 0.2
|
2612 |
EN300-171481_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCC5)OCCO |
−6.3
± 0.3
|
4.6
± 0.2
|
2613 |
EN300-396146_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CO)CO |
−6.3
± 0.2
|
4.6
± 0.2
|
2614 |
EN300-71106_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCc6ncnn6C5 |
−6.3
± 0.2
|
4.6
± 0.1
|
2615 |
EN300-57949_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)NCc5ccccn5 |
−6.3
± 0.2
|
4.6
± 0.1
|
2616 |
EN300-366278_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(=O)NCC56COC6 |
−6.3
± 0.4
|
4.6
± 0.3
|
2617 |
EN300-179091_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)COC(F)F |
−6.3
± 0.2
|
4.6
± 0.2
|
2618 |
EN300-196614_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCc5[nH]cnn5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2619 |
EN300-7493197_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5ncc(c6)C(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2620 |
EN300-25986_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5cccn5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2621 |
EN300-365106_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)C(=O)N |
−6.3
± 0.2
|
4.6
± 0.2
|
2622 |
EN300-267089_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5[C@@H](CC[C@H]5CO)CO |
−6.3
± 0.3
|
4.6
± 0.2
|
2623 |
EN300-68618_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cocn5 |
−6.3
± 0.2
|
4.6
± 0.1
|
2624 |
EN300-42252_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn6cccnc6n5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2625 |
MAK-UNK-83e0a0b4-3
|
|
c1ccc2c(c1)cncc2N(CCNC3CNC3)C(=O)C4CCOc5c4cc(cc5)Cl |
−6.3
± 0.4
|
4.6
± 0.3
|
2626 |
EN300-1587691_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNC(=O)C5CCO |
−6.3
± 0.4
|
4.6
± 0.3
|
2627 |
EN300-314274_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cncc6c5CCNC6=O |
−6.3
± 0.3
|
4.6
± 0.2
|
2628 |
EN300-305567_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccn6c(c5)nnn6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2629 |
EN300-127843_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)NCC5CC5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2630 |
EN300-115058_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCC5)C(=O)N |
−6.3
± 0.2
|
4.6
± 0.2
|
2631 |
EN300-1721883_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)n6ccnn6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2632 |
EN300-331476_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5COC[C@@H]5O |
−6.3
± 0.2
|
4.6
± 0.2
|
2633 |
EN300-27314_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC(=O)N5CCOCC5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2634 |
EN300-239233_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCn5c(=O)cccn5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2635 |
EN300-71405_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5ccn[nH]5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2636 |
EN300-10170_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(CO)NC(=O)N |
−6.3
± 0.3
|
4.6
± 0.3
|
2637 |
EN300-6762830_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5C[C@@H]([C@H]([C@H]5O)O)O |
−6.3
± 0.3
|
4.6
± 0.2
|
2638 |
EN300-98038_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]c(=O)[nH]n5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2639 |
EN300-149296_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ncc(cn5)F |
−6.3
± 0.2
|
4.6
± 0.2
|
2640 |
EN300-66800_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)c5ccc(cc5)O |
−6.2
± 0.3
|
4.6
± 0.2
|
2641 |
EN300-11300_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5cc(=O)[nH]c(=O)[nH]5 |
−6.2
± 0.3
|
4.6
± 0.2
|
2642 |
EN300-60033_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)COCC5CCCO5 |
−6.2
± 0.2
|
4.6
± 0.2
|
2643 |
EN300-323327_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccn6c(n5)ccn6 |
−6.2
± 0.2
|
4.6
± 0.2
|
2644 |
EN300-256583_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CS(=O)(=O)C5 |
−6.2
± 0.4
|
4.6
± 0.3
|
2645 |
EN300-65383_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5cc[nH]c(=O)c5=O |
−6.2
± 0.3
|
4.6
± 0.2
|
2646 |
EN300-6732590_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ncnn5C6CCOCC6 |
−6.2
± 0.3
|
4.6
± 0.2
|
2647 |
EN300-1604951_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCNC(=O)C5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2648 |
EN300-67023_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CS(=O)(=O)CC5CCCO5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2649 |
EN300-78135_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(=O)NC5CC5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2650 |
EN300-53433_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCNC(=O)c5cnccn5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2651 |
EN300-7442191_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CN6CCC5CC6)O |
−6.2
± 0.3
|
4.5
± 0.2
|
2652 |
EN300-378044_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CC=CCO5 |
−6.2
± 0.2
|
4.5
± 0.1
|
2653 |
EN300-716207_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)C(CO)(F)F |
−6.2
± 0.3
|
4.5
± 0.2
|
2654 |
EN300-344563_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(c6[nH]nnn6)O |
−6.2
± 0.3
|
4.5
± 0.2
|
2655 |
EN300-41549_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)CNC(=O)N |
−6.2
± 0.3
|
4.5
± 0.3
|
2656 |
EN300-269453_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCc6nnnn6C5 |
−6.2
± 0.2
|
4.5
± 0.1
|
2657 |
EN300-7427197_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCN(CC5)C6COC6 |
−6.2
± 0.2
|
4.5
± 0.2
|
2658 |
EN300-193679_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCCOC5)O |
−6.2
± 0.3
|
4.5
± 0.2
|
2659 |
EN300-97055_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c(=O)[nH]ccn5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2660 |
EN300-6472573_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(=O)NC6(C5)CC6 |
−6.2
± 0.3
|
4.5
± 0.2
|
2661 |
EN300-111006_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccncn5 |
−6.2
± 0.2
|
4.5
± 0.1
|
2662 |
EN300-342668_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC56CCN(C5)CC6 |
−6.2
± 0.2
|
4.5
± 0.2
|
2663 |
EN300-203940_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5[nH]ccc6=O |
−6.2
± 0.3
|
4.5
± 0.2
|
2664 |
EN300-6488157_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccc6n5cnn6 |
−6.2
± 0.3
|
4.5
± 0.2
|
2665 |
EN300-74167_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)C5CCOCC5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2666 |
EN300-1721667_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(=O)NC5CCC5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2667 |
EN300-1264911_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(CF)O |
−6.2
± 0.2
|
4.5
± 0.2
|
2668 |
EN300-35789_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cccnc5=O |
−6.2
± 0.2
|
4.5
± 0.2
|
2669 |
EN300-1178005_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(on5)C#N |
−6.2
± 0.2
|
4.5
± 0.2
|
2670 |
EN300-70489_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC(C5)C#N |
−6.2
± 0.3
|
4.5
± 0.2
|
2671 |
EN300-200426_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6n(n5)CCNC6=O |
−6.2
± 0.2
|
4.5
± 0.2
|
2672 |
EN300-222145_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5CNC(=O)N5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2673 |
VLA-UCB-34f3ed0c-1
|
|
C=C(C#N)C(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−6.2
± 0.2
|
4.5
± 0.2
|
2674 |
EN300-1968342_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(CF)O |
−6.2
± 0.2
|
4.5
± 0.1
|
2675 |
EN300-208236_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCc6c5nn[nH]6 |
−6.2
± 0.2
|
4.5
± 0.1
|
2676 |
EN300-318344_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ncco5 |
−6.2
± 0.2
|
4.5
± 0.1
|
2677 |
EN300-1592151_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc6ncnn6c5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2678 |
EN300-47606_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCC5CCS(=O)(=O)C5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2679 |
EN300-1723663_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCN(C(=O)C5)CCO |
−6.2
± 0.3
|
4.5
± 0.2
|
2680 |
EN300-311920_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCS(=O)(=O)C5)F |
−6.2
± 0.2
|
4.5
± 0.1
|
2681 |
EN300-75030_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCC(=O)N5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2682 |
EN300-243828_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnncc5O |
−6.2
± 0.3
|
4.5
± 0.2
|
2683 |
EN300-301703_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCOCC5)C(=O)N |
−6.2
± 0.2
|
4.5
± 0.1
|
2684 |
EN300-67478_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)NC(=O)N |
−6.2
± 0.4
|
4.5
± 0.3
|
2685 |
EN300-399606_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6n(n5)CCCC6O |
−6.2
± 0.2
|
4.5
± 0.1
|
2686 |
EN300-1110374_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccn(n5)C6CCNC6=O |
−6.2
± 0.2
|
4.5
± 0.1
|
2687 |
EN300-373791_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnn5CC#N |
−6.2
± 0.2
|
4.5
± 0.2
|
2688 |
EN300-307418_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CC5(C6)C(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2689 |
EN300-79606_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCCNC(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2690 |
EN300-124213_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CS(=O)(=O)CCO5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2691 |
EN300-44873_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCN5CCCS5(=O)=O |
−6.2
± 0.4
|
4.5
± 0.3
|
2692 |
EN300-253571_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCc6nnnn6CC5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2693 |
EN300-128464_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC(=O)NC5CC5 |
−6.2
± 0.3
|
4.5
± 0.2
|
2694 |
EN300-96159_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5[nH]cnn5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2695 |
EN300-1655839_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCn5cccnc5=O |
−6.2
± 0.3
|
4.5
± 0.2
|
2696 |
EN300-254908_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCOCC5)n6cnnn6 |
−6.2
± 0.4
|
4.5
± 0.3
|
2697 |
EN300-35778_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(CC5)C(=O)N |
−6.2
± 0.3
|
4.5
± 0.2
|
2698 |
EN300-42591_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)NC5CC5 |
−6.2
± 0.2
|
4.5
± 0.2
|
2699 |
EN300-7121836_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cn[nH]c5F |
−6.2
± 0.2
|
4.5
± 0.2
|
2700 |
EN300-149296_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ncc(cn5)F |
−6.2
± 0.2
|
4.5
± 0.2
|