Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2501 |
EN300-135530_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cccnc5C(=O)N |
−6.4
± 0.3
|
4.6
± 0.2
|
2502 |
EN300-155176_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCCS5(=O)=O |
−6.4
± 0.4
|
4.6
± 0.3
|
2503 |
EN300-1273172_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc(cn5)C(=O)N |
−6.4
± 0.3
|
4.6
± 0.2
|
2504 |
EN300-6762327_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(Cc5ccccn5)O |
−6.4
± 0.2
|
4.6
± 0.2
|
2505 |
EN300-107048_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5(CC5)CO |
−6.4
± 0.2
|
4.6
± 0.2
|
2506 |
EN300-219609_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5cnccc5=O |
−6.4
± 0.3
|
4.6
± 0.2
|
2507 |
EN300-73772_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5[nH]c(=O)[nH]n5 |
−6.4
± 0.2
|
4.6
± 0.2
|
2508 |
DAR-DIA-0d514e7d-13
|
|
C[C@H]1COc2c(cc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)c5ccc(cc5)F |
−6.4
± 0.2
|
4.6
± 0.1
|
2509 |
EN300-85760_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCO5 |
−6.4
± 0.2
|
4.6
± 0.1
|
2510 |
EN300-82616_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCNC5=O |
−6.4
± 0.2
|
4.6
± 0.2
|
2511 |
EN300-196870_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCCS(=O)(=O)C5 |
−6.4
± 0.3
|
4.6
± 0.2
|
2512 |
EN300-748981_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCn6c5nnc6 |
−6.4
± 0.3
|
4.6
± 0.2
|
2513 |
EN300-123614_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)NC(=O)N |
−6.4
± 0.3
|
4.6
± 0.2
|
2514 |
EN300-248521_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C(C5)O)CO |
−6.4
± 0.2
|
4.6
± 0.2
|
2515 |
EN300-7465925_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5CCNC(=O)C5 |
−6.4
± 0.3
|
4.6
± 0.2
|
2516 |
EN300-239825_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC5c6[nH]nnn6 |
−6.4
± 0.3
|
4.6
± 0.2
|
2517 |
EN300-205779_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCC5CCC(=O)N5 |
−6.4
± 0.2
|
4.6
± 0.2
|
2518 |
EN300-379570_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)COCCO6 |
−6.4
± 0.2
|
4.6
± 0.2
|
2519 |
EN300-225165_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CC(=O)NC(=O)C5 |
−6.4
± 0.4
|
4.6
± 0.3
|
2520 |
EN300-304771_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCN(C5=O)C6CC6 |
−6.4
± 0.3
|
4.6
± 0.2
|
2521 |
EN300-156995_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCc5c[nH]nn5 |
−6.4
± 0.3
|
4.6
± 0.2
|
2522 |
EN300-1726153_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccn6c5nnc6 |
−6.4
± 0.3
|
4.6
± 0.2
|
2523 |
EN300-69368_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCOCC5)O |
−6.4
± 0.3
|
4.6
± 0.2
|
2524 |
EN300-305294_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CC(C6C5)O |
−6.4
± 0.2
|
4.6
± 0.1
|
2525 |
EN300-104088_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)OCCO |
−6.4
± 0.3
|
4.6
± 0.2
|
2526 |
EN300-80390_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccn(n5)CCC(=O)N |
−6.4
± 0.3
|
4.6
± 0.2
|
2527 |
EN300-208236_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCc6c5nn[nH]6 |
−6.4
± 0.2
|
4.6
± 0.2
|
2528 |
EN300-7354033_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C56CC(C5)S(=O)(=O)C6 |
−6.4
± 0.3
|
4.6
± 0.2
|
2529 |
EN300-26147_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5cncn5 |
−6.4
± 0.3
|
4.6
± 0.2
|
2530 |
EN300-6746778_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5[nH]c(=O)ccn5 |
−6.4
± 0.3
|
4.6
± 0.2
|
2531 |
EN300-872798_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5c(nnn5)C6CC6 |
−6.4
± 0.3
|
4.6
± 0.2
|
2532 |
EN300-118045_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc([nH]c5=O)C6CC6 |
−6.4
± 0.3
|
4.6
± 0.2
|
2533 |
EN300-126389_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5COC(=O)N5 |
−6.4
± 0.2
|
4.6
± 0.2
|
2534 |
EN300-52383_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)Cn5cncn5 |
−6.4
± 0.3
|
4.6
± 0.2
|
2535 |
EN300-195790_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H](CCO)CO |
−6.4
± 0.3
|
4.6
± 0.2
|
2536 |
EN300-11300_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5cc(=O)[nH]c(=O)[nH]5 |
−6.4
± 0.2
|
4.6
± 0.2
|
2537 |
EN300-146491_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5CCCC(=O)N5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2538 |
EN300-68747_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCC5)C(=O)N |
−6.3
± 0.2
|
4.6
± 0.2
|
2539 |
EN300-19515_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(=O)N5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2540 |
EN300-51459_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(C(F)(F)F)O |
−6.3
± 0.3
|
4.6
± 0.2
|
2541 |
EN300-305996_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5COC(=O)N5 |
−6.3
± 0.2
|
4.6
± 0.1
|
2542 |
EN300-6745453_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5Cc6nncn6C5 |
−6.3
± 0.2
|
4.6
± 0.1
|
2543 |
EN300-125143_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCCC(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2544 |
EN300-69588_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCS(=O)CC5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2545 |
EN300-214849_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5nnc6n5nc[nH]6 |
−6.3
± 0.2
|
4.6
± 0.2
|
2546 |
EN300-103720_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc6n(n5)CCCO6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2547 |
EN300-7445540_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(nn5)C6(COC6)O |
−6.3
± 0.3
|
4.6
± 0.2
|
2548 |
EN300-08063_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)N5CCC(CC5)C(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2549 |
EN300-1605058_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(=O)NC(=O)C5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2550 |
EN300-173216_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(=O)NCC5CC5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2551 |
EN300-717493_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6CS(=O)(=O)C[C@@]6(C5)C#N |
−6.3
± 0.3
|
4.6
± 0.2
|
2552 |
EN300-312004_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnc6n5CCOCC6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2553 |
EN300-250533_2
|
|
C[C@]1(C[C@@H](C1)NC(=O)CC[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5)O |
−6.3
± 0.2
|
4.6
± 0.2
|
2554 |
EN300-184266_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5CC(=O)N5 |
−6.3
± 0.2
|
4.6
± 0.1
|
2555 |
EN300-08033_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCS(=O)(=O)C5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2556 |
EN300-88656_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCS5(=O)=O |
−6.3
± 0.2
|
4.6
± 0.1
|
2557 |
EN300-322161_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCn6ccnc6C5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2558 |
EN300-1692359_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCC5CO)CO |
−6.3
± 0.3
|
4.6
± 0.2
|
2559 |
EN300-313366_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C56CCN(C5)CC6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2560 |
EN300-140582_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5COCCN5CC(F)F |
−6.3
± 0.2
|
4.6
± 0.1
|
2561 |
EN300-1425608_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C(C5)CO)CCO |
−6.3
± 0.3
|
4.6
± 0.2
|
2562 |
EN300-343582_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCS(=O)(=O)CC5)C(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2563 |
EN300-6763991_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5nnc6n5CCOC6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2564 |
EN300-31102_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCN(CC5)S(=O)(=O)N |
−6.3
± 0.4
|
4.6
± 0.3
|
2565 |
EN300-248618_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CS(=O)(=O)C5CC5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2566 |
EN300-6479181_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC6N5C(=O)CC6 |
−6.3
± 0.2
|
4.6
± 0.1
|
2567 |
EN300-7425362_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CCOCC(=O)N6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2568 |
EN300-86205_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5c(=O)[nH]cnc5O |
−6.3
± 0.3
|
4.6
± 0.3
|
2569 |
EN300-1452069_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CC5CCOCC5)O |
−6.3
± 0.3
|
4.6
± 0.2
|
2570 |
EN300-261365_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CS(=O)(=O)C5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2571 |
EN300-251562_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc6n5nccc6 |
−6.3
± 0.2
|
4.6
± 0.2
|
2572 |
EN300-31969_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CC(=O)N(C5)CC6CC6 |
−6.3
± 0.2
|
4.6
± 0.1
|
2573 |
EN300-102853_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc6nnnn6c5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2574 |
EN300-6763072_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CS(=O)(=O)C56CC(C5)C6 |
−6.3
± 0.4
|
4.6
± 0.3
|
2575 |
EN300-55498_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COc5ccc(cc5)C(=O)N |
−6.3
± 0.2
|
4.6
± 0.2
|
2576 |
EN300-133915_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5csc(=O)[nH]5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2577 |
EN300-132613_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c(scn5)S(=O)(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2578 |
EN300-39305_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCS(=O)(=O)CC5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2579 |
EN300-220676_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCCS(=O)(=O)C5 |
−6.3
± 0.2
|
4.6
± 0.1
|
2580 |
EN300-266183_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CS(=O)(=O)C5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2581 |
EN300-1703015_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(=O)Nc5[nH]ccn5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2582 |
EN300-321951_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCN5CC[C@@H](C5)O |
−6.3
± 0.3
|
4.6
± 0.2
|
2583 |
EN300-2924757_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(cc5)CC(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2584 |
EN300-79022_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cccnn5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2585 |
EN300-188650_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5[nH]ccn5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2586 |
EN300-28571_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccnc5n6cncn6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2587 |
EN300-325737_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6ccccn6nn5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2588 |
EN300-303598_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nc(cs5)C(=O)N |
−6.3
± 0.3
|
4.6
± 0.2
|
2589 |
EN300-6745453_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5Cc6nncn6C5 |
−6.3
± 0.2
|
4.6
± 0.2
|
2590 |
EN300-204161_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5ccc[nH]c5=O |
−6.3
± 0.2
|
4.6
± 0.2
|
2591 |
EN300-269863_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc6c5CC(=O)N6 |
−6.3
± 0.3
|
4.6
± 0.2
|
2592 |
EN300-18064_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC5 |
−6.3
± 0.3
|
4.6
± 0.2
|
2593 |
EN300-781107_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)(CO)O |
−6.3
± 0.3
|
4.6
± 0.3
|
2594 |
EN300-7459916_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COC(=O)CO |
−6.3
± 0.2
|
4.6
± 0.2
|
2595 |
EN300-108236_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(nn5)CO |
−6.3
± 0.2
|
4.6
± 0.2
|
2596 |
EN300-7535791_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCC(CC5)(CO)CO |
−6.3
± 0.3
|
4.6
± 0.2
|
2597 |
EN300-154700_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)(CO)CO |
−6.3
± 0.3
|
4.6
± 0.2
|
2598 |
EN300-222620_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cc(cnc5)O |
−6.3
± 0.3
|
4.6
± 0.2
|
2599 |
EN300-208993_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N6CCNC6=O |
−6.3
± 0.3
|
4.6
± 0.2
|
2600 |
EN300-6731821_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(=O)nc[nH]5 |
−6.3
± 0.3
|
4.6
± 0.2
|