Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2301 |
EN300-122849_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC5c6ncon6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2302 |
EN300-6493892_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCc5c[nH]nn5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2303 |
EN300-367589_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(=O)NCC56COC6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2304 |
EN300-7430501_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCn6c(cnn6)C5 |
−6.6
± 0.1
|
4.8
± 0.1
|
2305 |
EN300-114593_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5cccn6 |
−6.6
± 0.2
|
4.8
± 0.2
|
2306 |
EN300-151298_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(cnc5)n6ccnn6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2307 |
EN300-12440_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CC(=O)N(C5)C6CC6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2308 |
EN300-74450_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]ccn5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2309 |
EN300-396535_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCC5)S(=O)(=O)N |
−6.6
± 0.3
|
4.8
± 0.2
|
2310 |
EN300-152337_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(=O)NCC5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2311 |
EN300-79022_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccnn5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2312 |
EN300-62192_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CC(=O)NC(=O)C5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2313 |
EN300-6735024_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@]6(C5)C[C@@H](CNC6=O)O |
−6.6
± 0.3
|
4.8
± 0.2
|
2314 |
EN300-20181_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)CCO |
−6.6
± 0.5
|
4.8
± 0.3
|
2315 |
EN300-3013783_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ncnn5c6ncccn6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2316 |
EN300-77885_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CO)C5CC5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2317 |
EN300-25702_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)O |
−6.6
± 0.2
|
4.8
± 0.1
|
2318 |
EN300-141224_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCn6c(ncn6)C5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2319 |
EN300-6729573_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCN5CCNC5=O |
−6.6
± 0.3
|
4.8
± 0.2
|
2320 |
EN300-67573_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NC5CCOCC5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2321 |
ADA-UCB-dc2b944c-9
|
|
c1ccc2c(c1)cnc(c2NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl)Br |
−6.6
± 0.1
|
4.8
± 0.1
|
2322 |
EN300-249804_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCOC(=O)N5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2323 |
EN300-227021_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5[nH]cnn5 |
−6.6
± 0.2
|
4.8
± 0.2
|
2324 |
EN300-5638430_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CS(=O)(=O)C5 |
−6.6
± 0.3
|
4.8
± 0.2
|
2325 |
EN300-658865_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc([nH]n5)CO |
−6.6
± 0.2
|
4.8
± 0.2
|
2326 |
EN300-1452069_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(CC5CCOCC5)O |
−6.6
± 0.4
|
4.8
± 0.3
|
2327 |
EN300-6499531_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCCCS5(=O)=O |
−6.6
± 0.2
|
4.8
± 0.2
|
2328 |
EN300-7457159_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5cc(on5)C6(COC6)O |
−6.6
± 0.3
|
4.8
± 0.2
|
2329 |
EN300-7562761_2
|
|
CS(=O)(=O)[C@H]1C[C@@H](C1)CNC(=O)CC[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5 |
−6.6
± 0.3
|
4.8
± 0.2
|
2330 |
EN300-54837_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5C(=O)CCCC5=O |
−6.6
± 0.3
|
4.8
± 0.2
|
2331 |
EN300-113218_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CSC5CCOC5=O |
−6.6
± 0.2
|
4.8
± 0.1
|
2332 |
EN300-10673_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)C5CCS(=O)(=O)C5 |
−6.6
± 0.4
|
4.8
± 0.3
|
2333 |
EN300-188316_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(CO)C5CCOC5 |
−6.6
± 0.2
|
4.8
± 0.1
|
2334 |
EN300-169955_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5C(CC(=O)N5)C(F)(F)F |
−6.6
± 0.2
|
4.8
± 0.1
|
2335 |
EN300-188174_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc6c(n5)[nH]c(=O)o6 |
−6.6
± 0.2
|
4.8
± 0.2
|
2336 |
EN300-309521_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)c6nccnn6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2337 |
EN300-1083988_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNC(=O)C(C5)(F)F |
−6.6
± 0.3
|
4.8
± 0.2
|
2338 |
EN300-154201_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC5CO |
−6.6
± 0.2
|
4.8
± 0.1
|
2339 |
EN300-821186_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5ncc6c(n5)[nH]nn6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2340 |
EN300-52167_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccn(n5)CC(=O)N |
−6.6
± 0.2
|
4.8
± 0.2
|
2341 |
DAR-DIA-0d514e7d-11
|
|
C[C@@H]1COc2ccc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)C#N |
−6.56
± 0.07
|
4.78
± 0.05
|
2342 |
EN300-95642_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5c[nH]c(=O)[nH]c5=O |
−6.6
± 0.2
|
4.8
± 0.2
|
2343 |
EN300-151330_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)c6cccnc6 |
−6.6
± 0.3
|
4.8
± 0.2
|
2344 |
EN300-298869_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCOC5)OCCO |
−6.6
± 0.2
|
4.8
± 0.2
|
2345 |
EN300-42007_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCN(CC5)CC(=O)N |
−6.6
± 0.3
|
4.8
± 0.2
|
2346 |
EN300-6732769_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)C6CC(=O)NC6=O |
−6.6
± 0.2
|
4.8
± 0.1
|
2347 |
EN300-257315_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCn5cnnc5 |
−6.6
± 0.3
|
4.8
± 0.2
|
2348 |
EN300-67191_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCN5CCCC5=O |
−6.6
± 0.3
|
4.8
± 0.2
|
2349 |
EN300-187253_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(=O)N(C5)CC6CC6 |
−6.6
± 0.2
|
4.8
± 0.2
|
2350 |
EN300-7431365_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6n(c5)CCCNC6=O |
−6.5
± 0.3
|
4.8
± 0.2
|
2351 |
EN300-123614_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)NC(=O)N |
−6.5
± 0.2
|
4.8
± 0.2
|
2352 |
EN300-205047_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6c(c[nH]5)S(=O)(=O)CC6 |
−6.5
± 0.3
|
4.8
± 0.2
|
2353 |
EN300-50488_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)OCC(F)(F)F |
−6.5
± 0.3
|
4.8
± 0.2
|
2354 |
JOH-UNI-f51e3bbc-4
|
|
COc1c(c2ccccc2cn1)NC(=O)C3CCOc4c3cc(cc4)Cl |
−6.5
± 0.1
|
4.77
± 0.10
|
2355 |
EN300-41375_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCC5 |
−6.5
± 0.5
|
4.8
± 0.3
|
2356 |
EN300-135530_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccnc5C(=O)N |
−6.5
± 0.3
|
4.8
± 0.2
|
2357 |
EN300-217107_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC5C(=O)N |
−6.5
± 0.1
|
4.8
± 0.1
|
2358 |
EN300-378316_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5nnc6n5cc[nH]c6=O |
−6.5
± 0.2
|
4.8
± 0.2
|
2359 |
EN300-223741_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)S(=O)(=O)N |
−6.5
± 0.3
|
4.8
± 0.2
|
2360 |
EN300-2011576_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5Cc6c(nccn6)C5 |
−6.5
± 0.3
|
4.8
± 0.2
|
2361 |
EN300-117059_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CC5)CO |
−6.5
± 0.3
|
4.8
± 0.2
|
2362 |
EN300-95639_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C(C5)O)CO |
−6.5
± 0.2
|
4.8
± 0.1
|
2363 |
EN300-246423_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5(CCC5)O |
−6.5
± 0.3
|
4.8
± 0.2
|
2364 |
EN300-51889_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCC(=O)N5CCC(CC5)O |
−6.5
± 0.3
|
4.8
± 0.2
|
2365 |
EN300-1068231_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn6ccncc6n5 |
−6.5
± 0.2
|
4.8
± 0.2
|
2366 |
EN300-202232_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(C(=O)C5)C6CC6 |
−6.5
± 0.2
|
4.8
± 0.1
|
2367 |
EN300-34542_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCCC5C(=O)N |
−6.5
± 0.2
|
4.8
± 0.2
|
2368 |
EN300-16772_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCO |
−6.5
± 0.3
|
4.8
± 0.2
|
2369 |
EN300-298550_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)N6CCOC6=O |
−6.5
± 0.2
|
4.8
± 0.1
|
2370 |
EN300-101443_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(COC5)O |
−6.5
± 0.2
|
4.8
± 0.2
|
2371 |
EN300-6736649_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CC(CO5)CC(=O)N |
−6.5
± 0.2
|
4.8
± 0.2
|
2372 |
EN300-1698650_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCn5ccnn5 |
−6.5
± 0.2
|
4.8
± 0.1
|
2373 |
EN300-80522_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COCC5CCOC5 |
−6.5
± 0.2
|
4.8
± 0.2
|
2374 |
EN300-203306_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)(C(=O)N)O |
−6.5
± 0.3
|
4.8
± 0.2
|
2375 |
EN300-393056_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCS(=O)(=O)CC5CCO |
−6.5
± 0.2
|
4.7
± 0.2
|
2376 |
EN300-39439_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCC(=O)N |
−6.5
± 0.2
|
4.7
± 0.1
|
2377 |
EN300-6482296_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5COC6C5COC6 |
−6.5
± 0.2
|
4.7
± 0.2
|
2378 |
EN300-1704723_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)CCCF |
−6.5
± 0.3
|
4.7
± 0.2
|
2379 |
EN300-300519_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5csnn5 |
−6.5
± 0.2
|
4.7
± 0.2
|
2380 |
EN300-138676_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CC(=O)N)CC(F)(F)F |
−6.5
± 0.2
|
4.7
± 0.2
|
2381 |
EN300-1653482_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCn6c(nnn6)C5 |
−6.5
± 0.2
|
4.7
± 0.2
|
2382 |
EN300-79588_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCCS(=O)(=O)N |
−6.5
± 0.2
|
4.7
± 0.1
|
2383 |
EN300-28871_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCn5ccnn5 |
−6.5
± 0.2
|
4.7
± 0.1
|
2384 |
EN300-378343_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC=CC5CO |
−6.5
± 0.2
|
4.7
± 0.2
|
2385 |
EN300-77520_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)COC5CCOCC5 |
−6.5
± 0.2
|
4.7
± 0.2
|
2386 |
EN300-1228556_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)Cn6ccnn6 |
−6.5
± 0.2
|
4.7
± 0.2
|
2387 |
EN300-383906_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)N5CCCC5 |
−6.5
± 0.2
|
4.7
± 0.2
|
2388 |
EN300-121939_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN6C(C5)CCOC6=O |
−6.5
± 0.3
|
4.7
± 0.2
|
2389 |
EN300-13890_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CSC5CCS(=O)(=O)C5 |
−6.5
± 0.2
|
4.7
± 0.1
|
2390 |
EN300-1723991_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCN5CCCNC5=O |
−6.5
± 0.4
|
4.7
± 0.3
|
2391 |
EN300-1605226_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6(C5)CNC(=O)N6 |
−6.5
± 0.2
|
4.7
± 0.2
|
2392 |
EN300-182579_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CN(C5)CC(F)F |
−6.5
± 0.2
|
4.7
± 0.2
|
2393 |
EN300-817870_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(COC5)CCO |
−6.5
± 0.3
|
4.7
± 0.2
|
2394 |
EN300-7413100_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)CCO |
−6.5
± 0.2
|
4.7
± 0.1
|
2395 |
VLA-UCB-50c39ae8-7
|
|
C=CC(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−6.5
± 0.2
|
4.7
± 0.2
|
2396 |
EN300-42195_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(C5)CNC(=O)N |
−6.5
± 0.2
|
4.7
± 0.2
|
2397 |
EN300-08259_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCCCN5CCCC5=O |
−6.5
± 0.3
|
4.7
± 0.2
|
2398 |
EN300-19900_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnccn5 |
−6.5
± 0.2
|
4.7
± 0.1
|
2399 |
EDJ-MED-e4b030d8-7
|
|
COc1cc(cc2c1OCC[C@H]2C(=O)Nc3cncc4c3cccc4)Cl |
−6.5
± 0.2
|
4.7
± 0.1
|
2400 |
EN300-1655839_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5cccnc5=O |
−6.5
± 0.3
|
4.7
± 0.2
|