Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1701 |
EN300-28871_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCn5ccnn5 |
−7.2
± 0.2
|
5.2
± 0.1
|
1702 |
EN300-155823_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CC#N)O |
−7.2
± 0.2
|
5.2
± 0.2
|
1703 |
EN300-1698571_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCn5cnnn5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1704 |
EN300-262604_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cnc(n5)C(=O)N |
−7.2
± 0.3
|
5.2
± 0.2
|
1705 |
EN300-66518_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)n6cncn6 |
−7.2
± 0.2
|
5.2
± 0.1
|
1706 |
EN300-35428_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NC5CC5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1707 |
EN300-1448603_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5CCS(=O)(=O)C5 |
−7.2
± 0.2
|
5.2
± 0.1
|
1708 |
EN300-7443518_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6cncn6c(=O)[nH]5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1709 |
EN300-244947_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCc5c[nH]nn5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1710 |
ADA-UCB-dc2b944c-12
|
|
Cc1c2ccccc2c(cn1)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−7.16
± 0.09
|
5.22
± 0.06
|
1711 |
EN300-6499164_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(=O)NC6C5CC6 |
−7.2
± 0.2
|
5.2
± 0.1
|
1712 |
EN300-2011083_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCC(=O)OCC5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1713 |
EN300-396748_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc(c5)CO |
−7.2
± 0.3
|
5.2
± 0.2
|
1714 |
EN300-6743433_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccn6c(c5)cnn6 |
−7.2
± 0.3
|
5.2
± 0.2
|
1715 |
JOH-SUS-a69c159d-2
|
|
c1ccc2c(c1)c(cnc2F)NC(=O)C3CCOc4c3cc(cc4)Cl |
−7.16
± 0.08
|
5.21
± 0.06
|
1716 |
EN300-111159_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c(cc(=O)[nH]n5)O |
−7.2
± 0.2
|
5.2
± 0.2
|
1717 |
EN300-13287_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5ccc(=O)[nH]c5=O |
−7.2
± 0.2
|
5.2
± 0.2
|
1718 |
EN300-6482801_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC(C5)C6(CC6)O |
−7.2
± 0.3
|
5.2
± 0.2
|
1719 |
EN300-93074_1
|
|
CN(C(=O)C[C@@]1(c2c(ccc(c2)Cl)OCC1)C(=O)Nc3c4c(cnc3)cccc4)[C@H]5C[C@@H](C5)O |
−7.2
± 0.3
|
5.2
± 0.2
|
1720 |
EN300-94945_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCNC5=O |
−7.2
± 0.2
|
5.2
± 0.1
|
1721 |
EN300-19392_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCO |
−7.2
± 0.3
|
5.2
± 0.2
|
1722 |
EN300-129384_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCCCNC5=O |
−7.1
± 0.1
|
5.21
± 0.09
|
1723 |
EN300-36522_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)C5CC5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1724 |
EN300-1179673_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cccc(c5)C(=O)N |
−7.1
± 0.3
|
5.2
± 0.2
|
1725 |
EN300-223741_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)S(=O)(=O)N |
−7.1
± 0.3
|
5.2
± 0.2
|
1726 |
EN300-101197_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCc5[nH]cnn5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1727 |
EN300-70092_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)C(=O)N |
−7.1
± 0.2
|
5.2
± 0.1
|
1728 |
EN300-65853_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5ccc(cc5)C#N |
−7.1
± 0.3
|
5.2
± 0.2
|
1729 |
EN300-81512_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CC5)CO |
−7.1
± 0.2
|
5.2
± 0.2
|
1730 |
EN300-6731334_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C56CCN(CC5)S(=O)(=O)C6 |
−7.1
± 0.3
|
5.2
± 0.2
|
1731 |
EN300-256583_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CS(=O)(=O)C5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1732 |
EN300-221518_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCCO |
−7.1
± 0.1
|
5.20
± 0.08
|
1733 |
EN300-97300_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CC5F |
−7.1
± 0.2
|
5.2
± 0.2
|
1734 |
EN300-250120_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCS(=O)(=O)CC5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1735 |
EN300-140751_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnnn5CC6CC6 |
−7.1
± 0.3
|
5.2
± 0.2
|
1736 |
EN300-1448603_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CCS(=O)(=O)C5 |
−7.1
± 0.1
|
5.2
± 0.1
|
1737 |
EDJ-MED-28ec730d-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC5CCOCC5 |
−7.1
± 0.2
|
5.2
± 0.1
|
1738 |
EN300-72211_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(C5CC5)O |
−7.1
± 0.2
|
5.2
± 0.1
|
1739 |
EN300-298031_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CC5(C6)CO |
−7.1
± 0.3
|
5.2
± 0.2
|
1740 |
EN300-211158_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cc(cc(c5)CO)CO |
−7.1
± 0.3
|
5.2
± 0.2
|
1741 |
EN300-117059_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CC5)CO |
−7.1
± 0.3
|
5.2
± 0.2
|
1742 |
EN300-105267_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)Nc5cnccn5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1743 |
EN300-51889_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCC(=O)N5CCC(CC5)O |
−7.1
± 0.3
|
5.2
± 0.2
|
1744 |
EN300-373552_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cncc(n5)F |
−7.1
± 0.2
|
5.2
± 0.2
|
1745 |
EN300-60033_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COCC5CCCO5 |
−7.1
± 0.2
|
5.2
± 0.1
|
1746 |
EN300-01527_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCC5CCCO5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1747 |
EN300-181688_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cc6n(n5)CCO6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1748 |
EN300-223741_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CC5)S(=O)(=O)N |
−7.1
± 0.3
|
5.2
± 0.2
|
1749 |
EN300-45049_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCS(=O)(=O)N5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1750 |
EN300-716218_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCNC(=O)C56CC6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1751 |
EN300-176135_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnc6n5nccc6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1752 |
EN300-75464_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5c(=O)c6ccnn6cn5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1753 |
DAR-DIA-0d514e7d-16
|
|
C[C@H]1COc2c(cc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)c5ccccc5F |
−7.1
± 0.2
|
5.2
± 0.1
|
1754 |
EN300-08705_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCNC(=O)C5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1755 |
EN300-657320_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CSCC(=O)N5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1756 |
EN300-256583_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CS(=O)(=O)C5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1757 |
EN300-107435_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCCS5(=O)=O |
−7.1
± 0.2
|
5.2
± 0.1
|
1758 |
EN300-1268020_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)Cc6[nH]nnn6 |
−7.1
± 0.3
|
5.2
± 0.2
|
1759 |
EN300-1644723_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5C6C5COCC6 |
−7.1
± 0.2
|
5.2
± 0.1
|
1760 |
EN300-134855_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(c5cccnc5)O |
−7.1
± 0.2
|
5.2
± 0.2
|
1761 |
EN300-113507_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(=O)N |
−7.1
± 0.2
|
5.2
± 0.1
|
1762 |
EN300-120820_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cn[nH]c5=O |
−7.1
± 0.2
|
5.2
± 0.2
|
1763 |
EN300-173216_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(=O)NCC5CC5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1764 |
DAR-DIA-0d514e7d-20
|
|
C[C@H]1COc2c(cc(cc2N3CCOCC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1765 |
EN300-97661_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc[nH]c(=O)c5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1766 |
EN300-702756_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CS(=O)(=O)CC(=O)N5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1767 |
EN300-7547467_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCN(C5=O)c6ccn[nH]6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1768 |
EN300-104592_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCC5CCC(=O)N5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1769 |
EN300-6731334_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C56CCN(CC5)S(=O)(=O)C6 |
−7.1
± 0.3
|
5.2
± 0.2
|
1770 |
EN300-7426624_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnnn5C6CCC6 |
−7.1
± 0.3
|
5.2
± 0.2
|
1771 |
EN300-250416_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nc6ncccn6n5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1772 |
EN300-383906_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)N5CCCC5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1773 |
EN300-7426781_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c6cccn6ncn5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1774 |
EN300-109060_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)C(=O)CC#N |
−7.1
± 0.3
|
5.2
± 0.2
|
1775 |
EN300-1272707_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5CCO[C@@H]5c6[nH]cnn6 |
−7.1
± 0.3
|
5.2
± 0.2
|
1776 |
EN300-303519_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnn6c5OCC6 |
−7.1
± 0.3
|
5.2
± 0.2
|
1777 |
EN300-45049_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCS(=O)(=O)N5 |
−7.1
± 0.2
|
5.2
± 0.1
|
1778 |
EN300-120920_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC5CCC(=O)NC5=O |
−7.1
± 0.2
|
5.2
± 0.1
|
1779 |
EN300-1604607_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C56CC(C5)OC6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1780 |
EN300-1700143_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)c6ncon6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1781 |
EN300-115011_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCOCC5)CO |
−7.1
± 0.2
|
5.2
± 0.2
|
1782 |
EN300-332453_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CO)C(c5cccnc5)O |
−7.1
± 0.3
|
5.2
± 0.2
|
1783 |
EN300-188582_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@@H](C5)O |
−7.1
± 0.2
|
5.2
± 0.1
|
1784 |
EN300-6504697_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5CC6(CC6)S(=O)(=O)N5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1785 |
EN300-11441_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cc(=O)[nH]c(=O)[nH]5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1786 |
EN300-51736_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COc5cccc(c5)C(=O)N |
−7.1
± 0.3
|
5.2
± 0.2
|
1787 |
EN300-99899_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)c5cccnn5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1788 |
EN300-205047_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6c(c[nH]5)S(=O)(=O)CC6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1789 |
EN300-175400_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCn6c(cnn6)C5 |
−7.1
± 0.2
|
5.2
± 0.2
|
1790 |
EN300-69993_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCN(CC5)CCO |
−7.1
± 0.3
|
5.2
± 0.2
|
1791 |
EN300-81512_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)CO |
−7.1
± 0.2
|
5.2
± 0.2
|
1792 |
EN300-7448078_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6(CC5)C(CC6O)O |
−7.1
± 0.2
|
5.2
± 0.2
|
1793 |
EN300-157158_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC=CCO |
−7.1
± 0.1
|
5.16
± 0.10
|
1794 |
EN300-366468_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCNC(=O)C5 |
−7.1
± 0.3
|
5.2
± 0.2
|
1795 |
EN300-10334_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C56CCC(=O)N5CCS6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1796 |
EN300-7500507_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(COCCOC5)F |
−7.1
± 0.3
|
5.2
± 0.2
|
1797 |
EN300-181688_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cc6n(n5)CCO6 |
−7.1
± 0.2
|
5.2
± 0.2
|
1798 |
EN300-37077_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccn[nH]5 |
−7.1
± 0.2
|
5.2
± 0.1
|
1799 |
EN300-1251424_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccn(n5)CC#N |
−7.1
± 0.2
|
5.2
± 0.2
|
1800 |
EN300-260152_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cnns5 |
−7.1
± 0.2
|
5.2
± 0.2
|