Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1601 |
EN300-113633_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCC(=O)NC5=O |
−7.3
± 0.2
|
5.3
± 0.1
|
1602 |
EN300-366278_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(=O)NCC56COC6 |
−7.3
± 0.3
|
5.3
± 0.2
|
1603 |
EN300-6763072_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CS(=O)(=O)C56CC(C5)C6 |
−7.3
± 0.3
|
5.3
± 0.2
|
1604 |
EN300-71125_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCn6cnnc6C5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1605 |
EN300-1704723_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cn(nn5)CCCF |
−7.3
± 0.3
|
5.3
± 0.2
|
1606 |
EN300-31562_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5c[nH]nc5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1607 |
EN300-61086_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(C5CC5)C6CC(=O)NC6=O |
−7.3
± 0.2
|
5.3
± 0.2
|
1608 |
EN300-6474647_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6C(C5)CCNC6=O |
−7.3
± 0.1
|
5.28
± 0.10
|
1609 |
EN300-315836_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5[nH]ccn5 |
−7.3
± 0.1
|
5.28
± 0.10
|
1610 |
EN300-7459540_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC5C(CO)O |
−7.2
± 0.3
|
5.3
± 0.2
|
1611 |
EN300-6745581_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5nncn5C6CC6 |
−7.2
± 0.2
|
5.3
± 0.2
|
1612 |
EN300-68618_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cocn5 |
−7.2
± 0.2
|
5.3
± 0.1
|
1613 |
ALP-POS-477dc5b7-3
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCOc4c3cc(cc4)Cl)CCC5CC5 |
−7.2
± 0.1
|
5.3
± 0.1
|
1614 |
EN300-316193_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6COC(=O)[C@H]6C5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1615 |
EN300-1721883_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CC5)n6ccnn6 |
−7.2
± 0.2
|
5.3
± 0.2
|
1616 |
EN300-331993_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)Nc5[nH]ccn5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1617 |
EN300-367405_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)n6ccnn6 |
−7.2
± 0.2
|
5.3
± 0.1
|
1618 |
EN300-4293814_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CS(=O)(=O)CCO |
−7.2
± 0.5
|
5.3
± 0.4
|
1619 |
DAR-DIA-23e5a6a0-5
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4OC5CC6(N5)CC6)Cl |
−7.2
± 0.3
|
5.3
± 0.2
|
1620 |
EN300-135123_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5ccc(cc5)C(=O)N |
−7.2
± 0.3
|
5.3
± 0.2
|
1621 |
EN300-6488157_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cccc6n5cnn6 |
−7.2
± 0.3
|
5.3
± 0.2
|
1622 |
EN300-220527_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5[nH]ccn5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1623 |
EN300-761746_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5c(=O)[nH]c(=O)[nH]n5 |
−7.2
± 0.3
|
5.3
± 0.2
|
1624 |
EN300-128277_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(=O)NCC(F)F |
−7.2
± 0.2
|
5.3
± 0.2
|
1625 |
EN300-1425899_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CC[C@@H](C5)CS(=O)(=O)N |
−7.2
± 0.3
|
5.3
± 0.3
|
1626 |
EN300-195756_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5CCC(=O)N5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1627 |
EN300-178829_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC(=O)NCC5CC5 |
−7.2
± 0.3
|
5.3
± 0.2
|
1628 |
EN300-378316_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5nnc6n5cc[nH]c6=O |
−7.2
± 0.3
|
5.3
± 0.2
|
1629 |
EN300-269453_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCc6nnnn6C5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1630 |
EN300-210933_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCN(C5)C(=O)N |
−7.2
± 0.3
|
5.3
± 0.2
|
1631 |
EN300-37195_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NC5CCCCNC5=O |
−7.2
± 0.2
|
5.3
± 0.1
|
1632 |
EN300-18064_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOCC5 |
−7.2
± 0.2
|
5.3
± 0.1
|
1633 |
EN300-80230_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ncccn5 |
−7.2
± 0.1
|
5.26
± 0.10
|
1634 |
EN300-821316_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CC(=O)NCC6O |
−7.2
± 0.3
|
5.3
± 0.2
|
1635 |
EN300-90293_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCc6c([nH]nn6)C5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1636 |
EN300-7438451_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCn6c(nnn6)C5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1637 |
EN300-42819_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCC(=O)NC5 |
−7.2
± 0.3
|
5.3
± 0.2
|
1638 |
EN300-90142_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCC(C5)C(=O)N |
−7.2
± 0.3
|
5.3
± 0.2
|
1639 |
EN300-110245_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCS(=O)(=O)CC5CC5 |
−7.2
± 0.6
|
5.3
± 0.5
|
1640 |
EN300-98099_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(cs5)S(=O)(=O)N |
−7.2
± 0.3
|
5.3
± 0.2
|
1641 |
EN300-97758_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCF |
−7.2
± 0.2
|
5.3
± 0.1
|
1642 |
EN300-15368_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccccc5OCC(=O)N |
−7.2
± 0.3
|
5.3
± 0.2
|
1643 |
EN300-7456948_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cccnn5 |
−7.2
± 0.3
|
5.3
± 0.2
|
1644 |
EN300-62449_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCNC(=O)C5CCC5 |
−7.2
± 0.3
|
5.3
± 0.2
|
1645 |
EN300-256174_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)c5ccncn5 |
−7.2
± 0.3
|
5.3
± 0.2
|
1646 |
EN300-1267093_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@H]6C[C@@]6(C5)O |
−7.2
± 0.3
|
5.3
± 0.2
|
1647 |
EN300-37195_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NC5CCCCNC5=O |
−7.2
± 0.2
|
5.3
± 0.2
|
1648 |
EN300-1657635_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5COC[C@@H]5F |
−7.2
± 0.2
|
5.3
± 0.2
|
1649 |
EN300-134536_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccnn5CCO |
−7.2
± 0.2
|
5.3
± 0.2
|
1650 |
EN300-315792_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COCC(F)F |
−7.2
± 0.2
|
5.3
± 0.2
|
1651 |
EN300-781107_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)(CO)O |
−7.2
± 0.3
|
5.3
± 0.2
|
1652 |
EN300-62808_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnc[nH]5 |
−7.2
± 0.2
|
5.3
± 0.2
|
1653 |
EN300-187385_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5ccc(=O)[nH]c5 |
−7.2
± 0.3
|
5.3
± 0.2
|
1654 |
EN300-93491_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnnn5C6CC6 |
−7.2
± 0.3
|
5.2
± 0.2
|
1655 |
ALP-POS-d3acb8cc-1
|
|
C[C@H]1C[C@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.21
± 0.08
|
5.25
± 0.06
|
1656 |
EN300-4698402_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5C[C@H]5F |
−7.2
± 0.2
|
5.2
± 0.1
|
1657 |
EN300-35843_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5[nH]c(=O)[nH]n5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1658 |
EN300-7445540_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5cc(nn5)C6(COC6)O |
−7.2
± 0.3
|
5.2
± 0.2
|
1659 |
EN300-6735421_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5(CN(C5)C6CC6)CO |
−7.2
± 0.3
|
5.2
± 0.2
|
1660 |
DAR-DIA-0d514e7d-12
|
|
C[C@H]1COc2c(cc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)c5ccc(cc5F)F |
−7.2
± 0.2
|
5.2
± 0.2
|
1661 |
EN300-11441_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cc(=O)[nH]c(=O)[nH]5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1662 |
EN300-11300_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5cc(=O)[nH]c(=O)[nH]5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1663 |
EN300-1696962_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCCn5cnnn5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1664 |
EN300-306105_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(cn5)c6[nH]nnn6 |
−7.2
± 0.3
|
5.2
± 0.2
|
1665 |
EN300-28262_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ccnc6n5ncn6 |
−7.2
± 0.3
|
5.2
± 0.2
|
1666 |
EN300-54541_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCC(=O)N5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1667 |
EN300-74167_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)C5CCOCC5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1668 |
EN300-1251424_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ccn(n5)CC#N |
−7.2
± 0.2
|
5.2
± 0.2
|
1669 |
EN300-7493255_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(OCC56CC6)CO |
−7.2
± 0.3
|
5.2
± 0.2
|
1670 |
EN300-36845_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)C5CCCC5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1671 |
EN300-72211_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(C5CC5)O |
−7.2
± 0.2
|
5.2
± 0.1
|
1672 |
EN300-862094_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC5C(=O)N |
−7.2
± 0.2
|
5.2
± 0.2
|
1673 |
EN300-6745712_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC6(CC5)CNC(=O)N6 |
−7.2
± 0.3
|
5.2
± 0.2
|
1674 |
EN300-6953121_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5C[C@H]5F |
−7.2
± 0.2
|
5.2
± 0.2
|
1675 |
DAR-DIA-23e5a6a0-4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4OC5CC6(CC6)CN5)Cl |
−7.2
± 0.3
|
5.2
± 0.2
|
1676 |
EN300-6487630_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CS(=O)(=O)C5)CCO |
−7.2
± 0.4
|
5.2
± 0.3
|
1677 |
EN300-1654606_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5C[C@@H]5F |
−7.2
± 0.1
|
5.24
± 0.10
|
1678 |
EN300-1241327_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)N5CCOCC5 |
−7.2
± 0.2
|
5.2
± 0.1
|
1679 |
EN300-706065_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(C5(CCOCC5)O)(F)F |
−7.2
± 0.3
|
5.2
± 0.2
|
1680 |
EN300-7431620_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CC6(CC6)S(=O)(=O)N5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1681 |
EN300-73620_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCS(=O)(=O)CC5 |
−7.2
± 0.3
|
5.2
± 0.2
|
1682 |
EN300-6735421_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5(CN(C5)C6CC6)CO |
−7.2
± 0.4
|
5.2
± 0.3
|
1683 |
EN300-94945_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCNC5=O |
−7.2
± 0.2
|
5.2
± 0.2
|
1684 |
EN300-33999_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5[nH]nnn5 |
−7.2
± 0.2
|
5.2
± 0.1
|
1685 |
EN300-42270_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnsn5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1686 |
EN300-318305_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC6(C5)CS(=O)(=O)C6 |
−7.2
± 0.3
|
5.2
± 0.2
|
1687 |
EN300-102871_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CN(C5)c6ccncn6 |
−7.2
± 0.2
|
5.2
± 0.2
|
1688 |
EN300-383904_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCNC(=O)CO |
−7.2
± 0.3
|
5.2
± 0.2
|
1689 |
EN300-6760451_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nnc6n5cccc6 |
−7.2
± 0.2
|
5.2
± 0.1
|
1690 |
EN300-91609_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC6C5C6 |
−7.2
± 0.1
|
5.23
± 0.10
|
1691 |
EN300-139846_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(CO)(F)F |
−7.2
± 0.3
|
5.2
± 0.2
|
1692 |
EN300-19242_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CO |
−7.2
± 0.2
|
5.2
± 0.1
|
1693 |
EN300-53423_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCOC5 |
−7.2
± 0.2
|
5.2
± 0.1
|
1694 |
EN300-359842_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c6ccnn6ccn5 |
−7.2
± 0.2
|
5.2
± 0.2
|
1695 |
EN300-7549839_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn[nH]c5n6cnnn6 |
−7.2
± 0.2
|
5.2
± 0.2
|
1696 |
EN300-215607_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCn5cc(nn5)CO |
−7.2
± 0.3
|
5.2
± 0.2
|
1697 |
EN300-6737762_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCCNC5=O |
−7.2
± 0.2
|
5.2
± 0.2
|
1698 |
EN300-307190_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc6n5CCOC6 |
−7.2
± 0.3
|
5.2
± 0.2
|
1699 |
EN300-191114_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCn5cccnc5=O |
−7.2
± 0.2
|
5.2
± 0.2
|
1700 |
EN300-7493768_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC56CC(C5)S(=O)(=O)C6 |
−7.2
± 0.3
|
5.2
± 0.2
|