Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1501 |
EN300-188356_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCOC5)F |
−7.4
± 0.2
|
5.4
± 0.1
|
1502 |
EN300-1664603_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5ccn[nH]5 |
−7.4
± 0.3
|
5.4
± 0.2
|
1503 |
EN300-105267_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)Nc5cnccn5 |
−7.4
± 0.3
|
5.4
± 0.2
|
1504 |
EN300-69368_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCOCC5)O |
−7.4
± 0.3
|
5.4
± 0.2
|
1505 |
EN300-30536_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5c(cn[nH]5)C(=O)N |
−7.4
± 0.2
|
5.4
± 0.2
|
1506 |
EN300-223187_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5c6c(nn5)CCCC6 |
−7.3
± 0.3
|
5.4
± 0.2
|
1507 |
EN300-1932780_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(C(F)F)O |
−7.3
± 0.2
|
5.4
± 0.2
|
1508 |
EN300-368758_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)CC6CCCO6 |
−7.3
± 0.2
|
5.4
± 0.2
|
1509 |
EN300-7370063_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)CO |
−7.3
± 0.1
|
5.35
± 0.09
|
1510 |
EN300-211158_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(cc(c5)CO)CO |
−7.3
± 0.3
|
5.4
± 0.2
|
1511 |
EN300-7456948_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cccnn5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1512 |
EN300-1440321_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCC5)S(=O)(=O)N |
−7.3
± 0.3
|
5.3
± 0.2
|
1513 |
EN300-7431964_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CN(C5)C(=O)N |
−7.3
± 0.2
|
5.3
± 0.2
|
1514 |
EN300-1587757_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCCNS5(=O)=O |
−7.3
± 0.2
|
5.3
± 0.2
|
1515 |
EN300-6493892_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCc5c[nH]nn5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1516 |
EN300-333468_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnn(c5Cl)CCO |
−7.3
± 0.3
|
5.3
± 0.2
|
1517 |
EN300-6746622_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)NC(=O)N |
−7.3
± 0.2
|
5.3
± 0.2
|
1518 |
EN300-77092_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5OCCO5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1519 |
EN300-205486_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cnccc5O |
−7.3
± 0.3
|
5.3
± 0.2
|
1520 |
EN300-181558_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CCC(CC5)O)O |
−7.3
± 0.3
|
5.3
± 0.2
|
1521 |
EN300-24419_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c(ccs5)S(=O)(=O)N |
−7.3
± 0.3
|
5.3
± 0.2
|
1522 |
EN300-331993_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)Nc5[nH]ccn5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1523 |
EN300-304381_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)CC(=O)N |
−7.3
± 0.2
|
5.3
± 0.1
|
1524 |
EN300-131572_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5cncc6 |
−7.3
± 0.2
|
5.3
± 0.2
|
1525 |
EN300-208993_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)N6CCNC6=O |
−7.3
± 0.3
|
5.3
± 0.2
|
1526 |
EN300-1178209_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5c[nH]nn5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1527 |
EN300-373552_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cncc(n5)F |
−7.3
± 0.2
|
5.3
± 0.2
|
1528 |
EN300-331476_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5COC[C@@H]5O |
−7.3
± 0.2
|
5.3
± 0.1
|
1529 |
EN300-120569_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)CCCC#N |
−7.3
± 0.3
|
5.3
± 0.2
|
1530 |
EN300-6739414_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5Cc6ccnn6CC(C5)CO |
−7.3
± 0.2
|
5.3
± 0.1
|
1531 |
EN300-49064_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5COC5 |
−7.3
± 0.2
|
5.3
± 0.1
|
1532 |
EN300-7353973_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(CO)F |
−7.3
± 0.3
|
5.3
± 0.2
|
1533 |
EN300-227055_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CC(=O)NC5=O |
−7.3
± 0.2
|
5.3
± 0.1
|
1534 |
EN300-1087187_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CCC(=O)NC6C5 |
−7.3
± 0.1
|
5.3
± 0.1
|
1535 |
EN300-1215738_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCC5CCC(=O)NC5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1536 |
EN300-92031_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5nc(no5)c6[nH]cnn6 |
−7.3
± 0.2
|
5.3
± 0.2
|
1537 |
EN300-120255_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CCCOC5)C(=O)N |
−7.3
± 0.2
|
5.3
± 0.2
|
1538 |
EN300-135182_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cc(=O)n6c([nH]5)ncn6 |
−7.3
± 0.3
|
5.3
± 0.2
|
1539 |
DAR-DIA-0d514e7d-3
|
|
CC1(COc2ccc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)C |
−7.31
± 0.09
|
5.33
± 0.07
|
1540 |
EN300-6733137_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CC5)n6cncn6 |
−7.3
± 0.3
|
5.3
± 0.2
|
1541 |
EN300-6494361_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CNC(=O)O6 |
−7.3
± 0.1
|
5.3
± 0.1
|
1542 |
EN300-241988_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)N6CCC(C6)O |
−7.3
± 0.2
|
5.3
± 0.1
|
1543 |
EN300-294602_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccsc5S(=O)(=O)N |
−7.3
± 0.3
|
5.3
± 0.3
|
1544 |
EN300-144606_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cn[nH]c5S(=O)(=O)N |
−7.3
± 0.3
|
5.3
± 0.2
|
1545 |
EN300-716218_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCNC(=O)C56CC6 |
−7.3
± 0.3
|
5.3
± 0.2
|
1546 |
EN300-82179_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC(=O)N |
−7.3
± 0.2
|
5.3
± 0.2
|
1547 |
EN300-1387104_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCS5(=O)=O |
−7.3
± 0.2
|
5.3
± 0.2
|
1548 |
EN300-219427_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCn6c(c(nn6)CO)C5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1549 |
EN300-749499_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C5(CCOCC5)O)O |
−7.3
± 0.3
|
5.3
± 0.2
|
1550 |
EN300-264318_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CCOC(=O)N6 |
−7.3
± 0.3
|
5.3
± 0.2
|
1551 |
EN300-189729_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CCO6 |
−7.3
± 0.2
|
5.3
± 0.1
|
1552 |
EN300-7456499_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCS(=O)(=O)CCCO |
−7.3
± 0.4
|
5.3
± 0.3
|
1553 |
EN300-151423_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CCOCC5)O |
−7.3
± 0.3
|
5.3
± 0.2
|
1554 |
EN300-1081929_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CCS(=O)(=O)CC6C5 |
−7.3
± 0.2
|
5.3
± 0.1
|
1555 |
EN300-95507_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cc(on5)CO |
−7.3
± 0.2
|
5.3
± 0.2
|
1556 |
EN300-6760278_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CC6C(O5)CCO6 |
−7.3
± 0.3
|
5.3
± 0.2
|
1557 |
EN300-67191_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCN5CCCC5=O |
−7.3
± 0.3
|
5.3
± 0.2
|
1558 |
EN300-139846_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(CO)(F)F |
−7.3
± 0.3
|
5.3
± 0.2
|
1559 |
EN300-226314_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)C5CCS(=O)(=O)C5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1560 |
EN300-1428805_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5Cc6cncn6C(=O)N5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1561 |
EN300-6489696_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(Cc6ccn[nH]6)O |
−7.3
± 0.3
|
5.3
± 0.2
|
1562 |
EN300-108022_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5cnnn5 |
−7.3
± 0.3
|
5.3
± 0.2
|
1563 |
EN300-743350_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC6(C5)CCNC6=O |
−7.3
± 0.3
|
5.3
± 0.2
|
1564 |
EN300-16772_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCO |
−7.3
± 0.2
|
5.3
± 0.2
|
1565 |
EN300-7237143_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c([nH]c(=O)[nH]6)C5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1566 |
EN300-7470948_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5c(nco5)CO |
−7.3
± 0.3
|
5.3
± 0.2
|
1567 |
EN300-1072972_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCOC5=O |
−7.3
± 0.2
|
5.3
± 0.2
|
1568 |
EN300-99653_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOCC5)CC(=O)N |
−7.3
± 0.3
|
5.3
± 0.2
|
1569 |
EN300-106988_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5(CC5)C(=O)N |
−7.3
± 0.2
|
5.3
± 0.2
|
1570 |
EN300-07127_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC5C(=O)N |
−7.3
± 0.1
|
5.3
± 0.1
|
1571 |
EN300-154201_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOCC5CO |
−7.3
± 0.2
|
5.3
± 0.1
|
1572 |
EN300-7355519_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CC6C(O5)CCO6 |
−7.3
± 0.2
|
5.3
± 0.2
|
1573 |
EN300-114134_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCN5CCCS5(=O)=O |
−7.3
± 0.2
|
5.3
± 0.2
|
1574 |
DAR-DIA-23e5a6a0-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4CC5CC6(N5)CCC6)Cl |
−7.3
± 0.2
|
5.3
± 0.2
|
1575 |
EN300-317210_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CC(C6)O |
−7.3
± 0.2
|
5.3
± 0.2
|
1576 |
EN300-317272_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)CC6CCOC6 |
−7.3
± 0.2
|
5.3
± 0.1
|
1577 |
EN300-31553_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCS(=O)(=O)N |
−7.3
± 0.4
|
5.3
± 0.3
|
1578 |
EN300-42591_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)NC5CC5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1579 |
EN300-1600363_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5C[C@H]5C#N |
−7.3
± 0.2
|
5.3
± 0.2
|
1580 |
EN300-295372_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCn5ccnn5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1581 |
EN300-263085_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)n6cnnn6 |
−7.3
± 0.2
|
5.3
± 0.2
|
1582 |
EN300-175485_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@H](C5)CO |
−7.3
± 0.2
|
5.3
± 0.2
|
1583 |
EN300-146174_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)CO |
−7.3
± 0.3
|
5.3
± 0.2
|
1584 |
EN300-75342_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5ccnc5 |
−7.3
± 0.2
|
5.3
± 0.1
|
1585 |
EN300-219609_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5cnccc5=O |
−7.3
± 0.3
|
5.3
± 0.2
|
1586 |
EN300-1266218_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6c([nH]n5)nc[nH]c6=O |
−7.3
± 0.2
|
5.3
± 0.1
|
1587 |
EN300-1091448_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC5(CO)CO |
−7.3
± 0.3
|
5.3
± 0.2
|
1588 |
DAR-DIA-0d514e7d-14
|
|
C[C@H]1COc2c(cc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)c5cccc(c5F)F |
−7.3
± 0.2
|
5.3
± 0.2
|
1589 |
EN300-1666341_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5Cc6c(cn[nH]6)C5CO |
−7.3
± 0.3
|
5.3
± 0.2
|
1590 |
EN300-132141_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c(nc[nH]c6=O)C5 |
−7.3
± 0.2
|
5.3
± 0.1
|
1591 |
EN300-640503_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5C[C@H](C56CCOCC6)O |
−7.3
± 0.3
|
5.3
± 0.2
|
1592 |
EN300-1717443_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC56CS(=O)(=O)C6 |
−7.3
± 0.2
|
5.3
± 0.2
|
1593 |
EN300-195464_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NCC(F)F |
−7.3
± 0.2
|
5.3
± 0.2
|
1594 |
EN300-104395_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CCCO5 |
−7.3
± 0.2
|
5.3
± 0.2
|
1595 |
EN300-266299_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CC[C@@H](C5)O |
−7.3
± 0.2
|
5.3
± 0.2
|
1596 |
EN300-1692359_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCC5CO)CO |
−7.3
± 0.2
|
5.3
± 0.1
|
1597 |
EN300-106781_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5ccc(=O)[nH]c5=O |
−7.3
± 0.3
|
5.3
± 0.2
|
1598 |
EN300-6735421_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5(CN(C5)C6CC6)CO |
−7.3
± 0.3
|
5.3
± 0.2
|
1599 |
EN300-306105_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cn5)c6[nH]nnn6 |
−7.3
± 0.2
|
5.3
± 0.2
|
1600 |
EN300-210907_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C5CCS(=O)(=O)CC5)O |
−7.3
± 0.3
|
5.3
± 0.2
|