Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1101 |
EN300-246248_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5CCNC5=O |
−7.8
± 0.2
|
5.7
± 0.1
|
1102 |
ADA-UCB-dc2b944c-16
|
|
CC1(C[C@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4)C |
−7.77
± 0.10
|
5.66
± 0.07
|
1103 |
EN300-1608590_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5nc(on5)N6CCOCC6 |
−7.8
± 0.3
|
5.7
± 0.2
|
1104 |
EN300-6735568_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCc6nncn6C5 |
−7.8
± 0.2
|
5.7
± 0.1
|
1105 |
EN300-141628_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(c5)S(=O)(=O)N |
−7.8
± 0.3
|
5.7
± 0.2
|
1106 |
EN300-1590388_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5cc(cn5)C#N |
−7.8
± 0.3
|
5.7
± 0.2
|
1107 |
EN300-7435482_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C6(C5)CCOCC6)O |
−7.8
± 0.2
|
5.7
± 0.1
|
1108 |
EN300-51350_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCc6nncn6C5 |
−7.8
± 0.2
|
5.7
± 0.1
|
1109 |
EN300-1277662_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5C[C@H]5CO |
−7.8
± 0.2
|
5.7
± 0.2
|
1110 |
EN300-105693_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(COC5)CO |
−7.8
± 0.2
|
5.7
± 0.1
|
1111 |
EN300-11300_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5cc(=O)[nH]c(=O)[nH]5 |
−7.8
± 0.2
|
5.7
± 0.2
|
1112 |
EN300-136080_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)n6cc(nn6)C(=O)N |
−7.8
± 0.2
|
5.7
± 0.2
|
1113 |
EN300-317272_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)CC6CCOC6 |
−7.8
± 0.2
|
5.7
± 0.2
|
1114 |
EN300-07268_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc6c(c5)[nH]c(=O)c(=O)[nH]6 |
−7.8
± 0.3
|
5.7
± 0.2
|
1115 |
EN300-107493_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCNC(=O)C5 |
−7.8
± 0.2
|
5.7
± 0.2
|
1116 |
EN300-260696_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC(C5n6cccn6)O |
−7.8
± 0.2
|
5.7
± 0.1
|
1117 |
EN300-20496_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC5CCOC5=O |
−7.8
± 0.2
|
5.7
± 0.1
|
1118 |
EN300-69107_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(=O)NCC5 |
−7.8
± 0.2
|
5.6
± 0.1
|
1119 |
EN300-31969_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(=O)N(C5)CC6CC6 |
−7.8
± 0.2
|
5.6
± 0.1
|
1120 |
EN300-128715_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC(=O)NCC(F)(F)F |
−7.8
± 0.3
|
5.6
± 0.2
|
1121 |
EN300-85413_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CC(=O)N)C5CC5 |
−7.8
± 0.3
|
5.6
± 0.2
|
1122 |
EN300-316216_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCn5cncn5 |
−7.8
± 0.2
|
5.6
± 0.1
|
1123 |
EN300-226314_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)C5CCS(=O)(=O)C5 |
−7.8
± 0.3
|
5.6
± 0.2
|
1124 |
EN300-101443_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(COC5)O |
−7.8
± 0.2
|
5.6
± 0.2
|
1125 |
EN300-42269_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnns5 |
−7.8
± 0.3
|
5.6
± 0.2
|
1126 |
EN300-6504325_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCNS(=O)(=O)N |
−7.7
± 0.6
|
5.6
± 0.4
|
1127 |
EN300-370753_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CC[C@H](C5)C(=O)N |
−7.7
± 0.3
|
5.6
± 0.2
|
1128 |
EN300-1270299_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cn5)CO |
−7.7
± 0.2
|
5.6
± 0.1
|
1129 |
EN300-313410_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(ncn5)N6CCOCC6 |
−7.7
± 0.2
|
5.6
± 0.1
|
1130 |
EN300-1722713_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CC(=O)NC6 |
−7.7
± 0.2
|
5.6
± 0.2
|
1131 |
EN300-1253178_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NC5CC5 |
−7.7
± 0.2
|
5.6
± 0.1
|
1132 |
EN300-90531_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCCC5C(=O)N |
−7.7
± 0.3
|
5.6
± 0.2
|
1133 |
EN300-145616_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5cnc[nH]5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1134 |
EN300-1588907_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5[C@H]6CCO[C@H]6C[C@H]5CO |
−7.7
± 0.3
|
5.6
± 0.2
|
1135 |
EN300-658355_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CCNC(=O)O6 |
−7.7
± 0.2
|
5.6
± 0.2
|
1136 |
EN300-36111_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCCCC5=O |
−7.7
± 0.3
|
5.6
± 0.2
|
1137 |
EN300-124301_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCn5ccnn5 |
−7.7
± 0.3
|
5.6
± 0.2
|
1138 |
EN300-26147_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5cncn5 |
−7.7
± 0.3
|
5.6
± 0.2
|
1139 |
EN300-14437_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCS(=O)(=O)C5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1140 |
EN300-61636_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)C(=O)NC6CC6 |
−7.7
± 0.3
|
5.6
± 0.2
|
1141 |
EN300-343474_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCNC5=O |
−7.7
± 0.2
|
5.6
± 0.2
|
1142 |
EN300-98143_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5c(cn[nH]5)F |
−7.7
± 0.2
|
5.6
± 0.2
|
1143 |
EN300-142412_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCCC(=O)N |
−7.7
± 0.3
|
5.6
± 0.2
|
1144 |
EN300-305294_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CC(C6C5)O |
−7.7
± 0.1
|
5.63
± 0.07
|
1145 |
EN300-143449_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCN(=O)=O |
−7.7
± 0.3
|
5.6
± 0.2
|
1146 |
EN300-04614_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(=O)[nH]n5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1147 |
EN300-103722_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnn6c5OCCC6 |
−7.7
± 0.3
|
5.6
± 0.2
|
1148 |
EN300-7432415_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5C6(CCC6)OC(=O)N5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1149 |
EN300-1662365_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCc6ncnn6C5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1150 |
EN300-6478054_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOCC(C5)CO |
−7.7
± 0.2
|
5.6
± 0.2
|
1151 |
EN300-95639_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C(C5)O)CO |
−7.7
± 0.2
|
5.6
± 0.1
|
1152 |
EN300-06654_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cn5cncn5 |
−7.7
± 0.2
|
5.6
± 0.1
|
1153 |
EN300-221518_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCCO |
−7.72
± 0.10
|
5.62
± 0.07
|
1154 |
EN300-365106_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)C(=O)N |
−7.7
± 0.2
|
5.6
± 0.2
|
1155 |
EN300-24297_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5csnn5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1156 |
DAR-DIA-23e5a6a0-6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4CC5CCC6(N5)CCC6)Cl |
−7.7
± 0.2
|
5.6
± 0.2
|
1157 |
EN300-171752_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCOC5 |
−7.7
± 0.1
|
5.6
± 0.1
|
1158 |
DAR-DIA-0d514e7d-24
|
|
C[C@H]1COc2c(cc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)CC(C)C |
−7.7
± 0.2
|
5.6
± 0.1
|
1159 |
EN300-219330_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCN5CCOCC5=O |
−7.7
± 0.3
|
5.6
± 0.2
|
1160 |
EN300-1600363_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5C[C@H]5C#N |
−7.7
± 0.2
|
5.6
± 0.1
|
1161 |
EN300-7444106_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCc6nnnn6C5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1162 |
EN300-22879_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCCCC5C(=O)N |
−7.7
± 0.2
|
5.6
± 0.2
|
1163 |
EN300-7470991_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H](C[C@H]5CO)CO |
−7.7
± 0.3
|
5.6
± 0.2
|
1164 |
EN300-43939_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)CC(F)(F)F |
−7.7
± 0.3
|
5.6
± 0.2
|
1165 |
EN300-2007620_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(OCC5)CO |
−7.7
± 0.2
|
5.6
± 0.1
|
1166 |
EN300-33513_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CSCC(=O)N |
−7.7
± 0.2
|
5.6
± 0.2
|
1167 |
EN300-27261_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(nc5)n6cncn6 |
−7.7
± 0.2
|
5.6
± 0.2
|
1168 |
EN300-259060_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC(C5)(CC(=O)N)O |
−7.7
± 0.2
|
5.6
± 0.1
|
1169 |
EN300-67191_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCN5CCCC5=O |
−7.7
± 0.3
|
5.6
± 0.2
|
1170 |
EN300-1248250_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CN(C5)C(=O)N |
−7.7
± 0.2
|
5.6
± 0.2
|
1171 |
EN300-211422_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC5 |
−7.7
± 0.2
|
5.6
± 0.1
|
1172 |
EN300-92031_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5nc(no5)c6[nH]cnn6 |
−7.7
± 0.2
|
5.6
± 0.2
|
1173 |
EN300-249093_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOCC5CC(=O)N |
−7.7
± 0.3
|
5.6
± 0.2
|
1174 |
EN300-1707870_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)(CCO)CO |
−7.7
± 0.2
|
5.6
± 0.1
|
1175 |
EN300-7456499_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCS(=O)(=O)CCCO |
−7.7
± 0.3
|
5.6
± 0.2
|
1176 |
EN300-249764_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C5CCC5)O |
−7.7
± 0.2
|
5.6
± 0.1
|
1177 |
EN300-10397_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)N |
−7.7
± 0.2
|
5.6
± 0.2
|
1178 |
EN300-1071014_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC(=O)C56CCOCC6 |
−7.7
± 0.3
|
5.6
± 0.2
|
1179 |
EN300-154191_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)C5CCOCC5 |
−7.7
± 0.3
|
5.6
± 0.2
|
1180 |
EN300-13499_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCCNC(=O)N |
−7.7
± 0.4
|
5.6
± 0.3
|
1181 |
EN300-731622_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5COCCO5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1182 |
EN300-378044_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC=CCO5 |
−7.7
± 0.2
|
5.6
± 0.1
|
1183 |
EN300-121939_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6C(C5)CCOC6=O |
−7.7
± 0.2
|
5.6
± 0.1
|
1184 |
EN300-3451857_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCC(=O)NC5=O |
−7.7
± 0.2
|
5.6
± 0.2
|
1185 |
EN300-1256657_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCNC(=O)C5C6CC6 |
−7.7
± 0.3
|
5.6
± 0.2
|
1186 |
EN300-258081_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)OCCO |
−7.7
± 0.2
|
5.6
± 0.2
|
1187 |
EN300-214800_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCN5CCNC5=O |
−7.7
± 0.3
|
5.6
± 0.2
|
1188 |
EN300-42269_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cnns5 |
−7.7
± 0.2
|
5.6
± 0.1
|
1189 |
EN300-316216_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCn5cncn5 |
−7.7
± 0.2
|
5.6
± 0.1
|
1190 |
EN300-370967_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCN5CCOC5=O |
−7.7
± 0.2
|
5.6
± 0.1
|
1191 |
EN300-6733137_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)n6cncn6 |
−7.7
± 0.3
|
5.6
± 0.2
|
1192 |
EN300-60033_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COCC5CCCO5 |
−7.7
± 0.2
|
5.6
± 0.1
|
1193 |
EN300-42591_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)NC5CC5 |
−7.7
± 0.3
|
5.6
± 0.2
|
1194 |
EN300-98802_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)OCC(=O)N |
−7.7
± 0.2
|
5.6
± 0.1
|
1195 |
EN300-129424_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCC5O |
−7.7
± 0.1
|
5.6
± 0.1
|
1196 |
EN300-6479273_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c(cc(=O)n6c5COCC6)O |
−7.7
± 0.3
|
5.6
± 0.2
|
1197 |
EN300-378373_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC5CC5 |
−7.7
± 0.2
|
5.6
± 0.2
|
1198 |
EN300-7459768_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC(C5)(C6(CCC6)O)O |
−7.7
± 0.3
|
5.6
± 0.2
|
1199 |
EN300-152756_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H](C[C@H]5CO)O |
−7.7
± 0.3
|
5.6
± 0.2
|
1200 |
EN300-14949_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cc5)OCC(=O)N |
−7.7
± 0.3
|
5.6
± 0.2
|