| Rank |
Microstate |
SMILES |
ΔG / kcal M-1 |
| 4401 |
EN300-1265949_3_1 |
|
C[C@@H](C(=O)N1CCS(=O)(=O)CC1)OCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4402 |
EN300-97699_1_1 |
|
C[C@@H](CS(=O)(=O)C)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4403 |
EN300-370280_1_1 |
|
C[C@]1(CCC(=O)N1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4404 |
EN300-53395_3_1 |
|
CCS(=O)(=O)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4405 |
EN300-263085_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)n6cnnn6 |
−9.8
± 0.4
|
| 4406 |
EN300-7444106_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCc6nnnn6C5 |
−9.8
± 0.2
|
| 4407 |
EN300-383664_1_1 |
|
Cn1cc(ncc1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4408 |
EN300-206592_1_1 |
|
CCC[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−9.8
± 0.3
|
| 4409 |
EN300-396329_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@@H]5C[C@@H]5CO |
−9.8
± 0.3
|
| 4410 |
EN300-256513_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CC5)CC(=O)N |
−9.8
± 0.3
|
| 4411 |
EN300-368758_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)C[C@@H]6CCCO6 |
−9.8
± 0.3
|
| 4412 |
EN300-107435_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CCCCS5(=O)=O |
−9.8
± 0.3
|
| 4413 |
EN300-30859_1_1 |
|
Cn1cnnc1CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4414 |
EN300-22880_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCC[C@@H](C5)C(=O)N |
−9.8
± 0.3
|
| 4415 |
EN300-307155_2_2 |
|
Cn1cnnc1[C@H](CO)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4416 |
EN300-104891_1_1 |
|
CNC(=O)c1cccc(n1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4417 |
EN300-24014_1_1 |
|
CS(=O)(=O)N1CCCC[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4418 |
EN300-1251424_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccn(n5)CC#N |
−9.8
± 0.3
|
| 4419 |
EN300-176877_3_1 |
|
CN(C)C(=O)CCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4420 |
EN300-256759_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CCC(=O)NCC5 |
−9.8
± 0.3
|
| 4421 |
EN300-244909_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCOCC5)CO |
−9.8
± 0.3
|
| 4422 |
EN300-7351945_2_1 |
|
CC1(C[C@@H](CNC1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.8
± 0.3
|
| 4423 |
EN300-56202_4_1 |
|
CC(=O)N1CSC[C@@H]1C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4424 |
EN300-69708_1_1 |
|
Cc1c(c(=O)n2c([nH]1)ccn2)CC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.4
|
| 4425 |
EN300-118760_2_2 |
|
C[C@](C1CC1)(C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.8
± 0.4
|
| 4426 |
EN300-364992_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC[C@H]5CC[C@H](O5)C(=O)N |
−9.8
± 0.4
|
| 4427 |
EN300-1911992_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]([C@@H]5CCOC5)O |
−9.8
± 0.4
|
| 4428 |
EN300-39826_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5nc6ncccn6n5 |
−9.8
± 0.2
|
| 4429 |
JAG-UCB-706446eb-1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(F)(F)F |
−9.8
± 0.2
|
| 4430 |
EN300-307336_1_3 |
|
C[C@@]1(C[C@H](CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O)CO |
−9.8
± 0.4
|
| 4431 |
EN300-311920_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@]5(CCS(=O)(=O)C5)F |
−9.8
± 0.3
|
| 4432 |
EN300-104493_2_3 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H](CO)[C@H]5CCOC5 |
−9.8
± 0.4
|
| 4433 |
EN300-90142_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCC[C@@H](C5)C(=O)N |
−9.8
± 0.3
|
| 4434 |
EN300-08259_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCCCN5CCCC5=O |
−9.8
± 0.4
|
| 4435 |
EN300-114894_1_1 |
|
CC1(OCCO1)CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4436 |
EN300-151411_1_1 |
|
CCn1c(c(nn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.8
± 0.3
|
| 4437 |
EN300-705386_4_1 |
|
COC[C@@H]1C[C@H]1C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4438 |
EN300-705386_4_1 |
|
COC[C@@H]1C[C@H]1C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4439 |
EN300-1697763_2_1 |
|
C[C@]1(CCCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C(=O)N |
−9.8
± 0.3
|
| 4440 |
EN300-386200_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC[C@H]([C@H](CC5)O)O |
−9.8
± 0.3
|
| 4441 |
EN300-42154_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CS(=O)(=O)C5CCCC5 |
−9.8
± 0.4
|
| 4442 |
EN300-107047_1_1 |
|
Cc1cc(=O)[nH]cc1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4443 |
EN300-245098_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC[C@@H]5C(=O)N |
−9.8
± 0.3
|
| 4444 |
EN300-1602334_2_1 |
|
Cc1c(cn2c(n1)ncn2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.4
|
| 4445 |
EN300-31147_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCNC(=O)C5CC5 |
−9.8
± 0.2
|
| 4446 |
EN300-157776_1_2 |
|
C[C@H]1CN(C[C@@H](O1)CO)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4447 |
EN300-314838_1_1 |
|
CCn1c(cnn1)CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4448 |
EN300-30768_4_2 |
|
C[C@H]1C[C@@H]1C(=O)NCC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4449 |
EN300-21409_1_1 |
|
C#CCNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.2
|
| 4450 |
EN300-21409_1_1 |
|
C#CCNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.2
|
| 4451 |
EN300-21009_4_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5CCCO5 |
−9.8
± 0.3
|
| 4452 |
EN300-7442191_1_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@]5(CN6CCC5CC6)O |
−9.8
± 0.4
|
| 4453 |
EN300-378316_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5nnc6n5cc[nH]c6=O |
−9.8
± 0.3
|
| 4454 |
EN300-199481_2_1 |
|
CC1(CNC(=O)CN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.8
± 0.3
|
| 4455 |
EN300-127487_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CC(=O)NC5 |
−9.8
± 0.3
|
| 4456 |
EN300-248526_1_1 |
|
c1ccc(cc1)[C@@](CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)(C(=O)N)O |
−9.8
± 0.3
|
| 4457 |
EN300-141695_4_2 |
|
CN1CC[C@H](C1=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4458 |
EN300-309457_1_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CN(C5)[C@H]6CCOC6 |
−9.8
± 0.4
|
| 4459 |
EN300-1709213_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@@H](C5)c6[nH]cnn6 |
−9.8
± 0.3
|
| 4460 |
EN300-2989643_2_1 |
|
Cn1c(cc(n1)OC)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4461 |
EN300-214552_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6c([nH]c(=O)[nH]6)nc5 |
−9.8
± 0.3
|
| 4462 |
EN300-110012_3_1 |
|
CC[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N(C)C |
−9.8
± 0.3
|
| 4463 |
EN300-124052_1_1 |
|
C[C@@H]1CN(C[C@@H]1O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4464 |
EN300-6738887_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C6CCC5[C@H](CC[C@H]6O)O |
−9.8
± 0.3
|
| 4465 |
EN300-1664603_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCc5ccn[nH]5 |
−9.8
± 0.3
|
| 4466 |
EN300-34705_1_1 |
|
CS(=O)(=O)N1CCC(CC1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4467 |
EN300-34705_1_1 |
|
CS(=O)(=O)N1CCC(CC1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4468 |
EN300-1605226_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CNC(=O)N6 |
−9.8
± 0.3
|
| 4469 |
EN300-185378_4_1 |
|
C[C@@H](COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.8
± 0.4
|
| 4470 |
EN300-817873_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6(C5)COCCO6 |
−9.8
± 0.3
|
| 4471 |
EN300-741926_2_4 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H]([C@H](C5)F)O |
−9.8
± 0.2
|
| 4472 |
EN300-74856_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCCS(=O)(=O)C5 |
−9.8
± 0.3
|
| 4473 |
EN300-83434_2_2 |
|
C[C@H]([C@@H](C)S(=O)(=O)C)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4474 |
EN300-160080_2_1 |
|
CS(=O)(=O)c1nnc(s1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4475 |
EN300-7431964_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CN(C5)C(=O)N |
−9.8
± 0.3
|
| 4476 |
EN300-805037_2_1 |
|
Cn1c2cc(c(=O)[nH]c2cn1)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.3
|
| 4477 |
EN300-137243_2_1 |
|
CN(C)c1ncc(o1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4478 |
EN300-6739162_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@H]6[C@H](C5)OC(=O)N6 |
−9.8
± 0.4
|
| 4479 |
EN300-198540_1_2 |
|
Cn1cc(cn1)[C@H](C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.8
± 0.3
|
| 4480 |
EN300-60049_2_3 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@@H]5CN6CCC[C@H]6CO5 |
−9.8
± 0.3
|
| 4481 |
EN300-62857_1_1 |
|
COCCS(=O)(=O)CCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.5
|
| 4482 |
EN300-3044054_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CCC(=O)N5C6CC6 |
−9.8
± 0.3
|
| 4483 |
EN300-10895_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NCCC#N |
−9.8
± 0.4
|
| 4484 |
EN300-1718675_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnnn5C6CC6 |
−9.8
± 0.4
|
| 4485 |
EN300-7352812_1_1 |
|
Cn1cc(cn1)OC2(CC2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.3
|
| 4486 |
EN300-13489_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCN(CC5)C(=O)N |
−9.8
± 0.3
|
| 4487 |
EN300-302058_1_2 |
|
CON1CC[C@H](C1=O)O[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4488 |
EN300-25572_2_1 |
|
C[C@@H]1CN(CCO1)C(=O)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4489 |
EN300-253443_3_1 |
|
CCCN1C[C@@H](CC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4490 |
EN300-245036_2_1 |
|
C[C@H]1[C@@H](CCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.8
± 0.3
|
| 4491 |
EN300-6335413_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5C[C@H]5C(=O)NCCO |
−9.8
± 0.4
|
| 4492 |
EN300-100741_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5[nH]cnn5 |
−9.8
± 0.3
|
| 4493 |
EN300-6736515_2_2 |
|
C[C@H]([C@@H]1COCCO1)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4494 |
EN300-682529_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@]5(CCOC5)CO |
−9.8
± 0.3
|
| 4495 |
EN300-2983332_1_2 |
|
CC(C)[C@H]1CNC(=O)CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4496 |
EN300-31184_3_1 |
|
C[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C(C)C |
−9.8
± 0.3
|
| 4497 |
EN300-234362_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@H](C5)n6cc(nn6)CO |
−9.8
± 0.4
|
| 4498 |
EN300-117931_2_1 |
|
CC(C)(CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.8
± 0.3
|
| 4499 |
EN300-31148_1_1 |
|
CCC(=O)N[C@@H](C)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.7
± 0.3
|
| 4500 |
EN300-305294_1_3 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H]6C[C@H]([C@@H]6C5)O |
−9.7
± 0.2
|