| Rank |
Microstate |
SMILES |
ΔG / kcal M-1 |
| 4301 |
EN300-98648_4_2 |
|
CN1CC[C@H](C1=O)OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4302 |
EN300-98648_4_2 |
|
CN1CC[C@H](C1=O)OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4303 |
EN300-13668_1_1 |
|
CN(CC(=O)NC1CC1)C(=O)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4304 |
EN300-72211_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H](C5CC5)O |
−9.8
± 0.3
|
| 4305 |
EN300-223491_4_1 |
|
Cn1cnn(c1=O)CCC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4306 |
EN300-1448603_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC[C@@H]5CCS(=O)(=O)C5 |
−9.8
± 0.3
|
| 4307 |
EN300-1448603_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC[C@@H]5CCS(=O)(=O)C5 |
−9.8
± 0.3
|
| 4308 |
EN300-1703015_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(=O)Nc5[nH]ccn5 |
−9.8
± 0.2
|
| 4309 |
EN300-657320_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5CSCC(=O)N5 |
−9.8
± 0.4
|
| 4310 |
EN300-79180_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H](C5CCOCC5)O |
−9.8
± 0.4
|
| 4311 |
EN300-1702677_1_1 |
|
CN1CC2(CN(C2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)C(C1=O)(F)F |
−9.8
± 0.3
|
| 4312 |
EN300-7355477_1_6 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6C[C@@H]([C@H](C[C@@H]6C5)O)O |
−9.8
± 0.3
|
| 4313 |
EN300-05754_2_2 |
|
C[C@H](C(=O)N1CCOCC1)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4314 |
EN300-238405_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@H]5CC(=O)NC5 |
−9.8
± 0.3
|
| 4315 |
EN300-6729572_4_1 |
|
C[C@@H]([C@@H]1C[C@@H]1C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.8
± 0.4
|
| 4316 |
EN300-304662_3_1 |
|
Cc1nnc(o1)CCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4317 |
EN300-205779_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC[C@@H]5CCC(=O)N5 |
−9.8
± 0.3
|
| 4318 |
EN300-02067_3_2 |
|
C[C@H](COC)NC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4319 |
EN300-385132_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5[nH]c(nn5)C6CCOCC6 |
−9.8
± 0.3
|
| 4320 |
EN300-20233_2_1 |
|
COCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.2
|
| 4321 |
EN300-6764836_2_5 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CC6[C@@H]([C@H](C5O6)O)O |
−9.8
± 0.3
|
| 4322 |
EN300-341337_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@]56CCO[C@@H]5CCOC6 |
−9.8
± 0.4
|
| 4323 |
EN300-1387145_1_2 |
|
CS(=O)(=O)[C@H]1CCC[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.8
|
| 4324 |
EN300-6974806_2_1 |
|
C[C@H]([C@@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−9.8
± 0.3
|
| 4325 |
EN300-103187_3_1 |
|
CCOCCNC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.4
|
| 4326 |
EN300-28177_2_2 |
|
C[C@H](C(=O)N1CCC[C@@H](C1)C(=O)N)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4327 |
EN300-177118_2_1 |
|
C[C@@]1(CCC(=O)N1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4328 |
EN300-60514_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5cc(cn5)S(=O)(=O)N |
−9.8
± 0.4
|
| 4329 |
EN300-1600517_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H](CO)F |
−9.8
± 0.4
|
| 4330 |
EN300-71125_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCn6cnnc6C5 |
−9.8
± 0.3
|
| 4331 |
EN300-3044054_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCC(=O)N5C6CC6 |
−9.8
± 0.3
|
| 4332 |
EN300-220228_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6ccnn6c5O |
−9.8
± 0.3
|
| 4333 |
EN300-741926_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H]([C@@H](C5)F)O |
−9.8
± 0.3
|
| 4334 |
EN300-64536_2_1 |
|
COCCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.2
|
| 4335 |
EN300-122340_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCSCC5)O |
−9.8
± 0.5
|
| 4336 |
EN300-7543383_1_2 |
|
CN1C(=O)[C@H](CO1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4337 |
EN300-33553_1_1 |
|
Cc1c(c(=O)[nH]cn1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4338 |
EN300-1262608_2_1 |
|
CCNC(=O)C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4339 |
EN300-93474_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5C[C@H](C=C5)CO |
−9.8
± 0.2
|
| 4340 |
EN300-1988306_1_1 |
|
CS(=O)(=O)CCC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.4
|
| 4341 |
EN300-35642_1_1 |
|
CN(CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−9.8
± 0.4
|
| 4342 |
EN300-12440_1_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CC(=O)N(C5)C6CC6 |
−9.8
± 0.3
|
| 4343 |
EN300-237224_2_1 |
|
CN1CCC(CC1)OCC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4344 |
EN300-307658_2_1 |
|
C=C[C@H](CO)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4345 |
EN300-650518_2_1 |
|
CO[C@@H]1C[C@H]1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4346 |
EN300-7355519_4_3 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C[C@@H]5C[C@H]6[C@@H](O5)CCO6 |
−9.8
± 0.5
|
| 4347 |
EN300-221122_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@](C5)(c6cnn[nH]6)O |
−9.8
± 0.4
|
| 4348 |
EN300-67533_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@H](C5CC5)O |
−9.8
± 0.3
|
| 4349 |
EN300-18064_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOCC5 |
−9.8
± 0.3
|
| 4350 |
EN300-6764450_1_1 |
|
CNC(=O)N1CCC(CC1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4351 |
EN300-1068239_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cnon5 |
−9.8
± 0.3
|
| 4352 |
EN300-260603_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5c[nH]c(=O)[nH]5 |
−9.8
± 0.3
|
| 4353 |
EN300-102347_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5(COC5)CO |
−9.8
± 0.2
|
| 4354 |
EN300-260760_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5cc(=O)[nH][nH]5 |
−9.8
± 0.2
|
| 4355 |
EN300-7459540_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@@H]5[C@@H](CO)O |
−9.8
± 0.5
|
| 4356 |
EN300-10729_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCNC(=O)N |
−9.8
± 0.3
|
| 4357 |
EN300-1268016_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5C[C@@H]6[C@@H]5C[C@@H](C6)C(=O)N |
−9.8
± 0.3
|
| 4358 |
EN300-7438575_2_2 |
|
C[C@H](C1=NO[C@H]2[C@@H]1COC2)NC(=O)CC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.3
|
| 4359 |
EN300-321597_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CC[C@H](C5)O |
−9.8
± 0.3
|
| 4360 |
EN300-7543132_1_1 |
|
CN(C)CCn1cc(nn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4361 |
EN300-7543132_1_1 |
|
CN(C)CCn1cc(nn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4362 |
EN300-649738_1_1 |
|
Cc1c(n(nn1)C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4363 |
EN300-22880_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCC[C@@H](C5)C(=O)N |
−9.8
± 0.3
|
| 4364 |
EN300-23129_2_1 |
|
CC(=O)NCCNC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4365 |
EN300-67050_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCS(=O)(=O)CC5 |
−9.8
± 0.3
|
| 4366 |
EN300-246423_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5(CCC5)O |
−9.8
± 0.3
|
| 4367 |
EN300-313438_2_1 |
|
Cn1c2c(cn1)c(ncn2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.3
|
| 4368 |
EN300-253187_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5COCO5 |
−9.8
± 0.3
|
| 4369 |
EN300-1073320_3_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H](C5(CCC5)O)O |
−9.8
± 0.3
|
| 4370 |
EN300-6746631_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nnc6n5CCCC6 |
−9.8
± 0.3
|
| 4371 |
EN300-247343_3_1 |
|
CC1(CC(C1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.8
± 0.3
|
| 4372 |
EN300-46832_4_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NC[C@H]5CCOC5 |
−9.8
± 0.3
|
| 4373 |
EN300-71126_1_1 |
|
Cc1nnc2n1CCN(C2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.8
± 0.3
|
| 4374 |
EN300-65839_4_1 |
|
CC[C@@H](C(=O)N)OCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.4
|
| 4375 |
EN300-36911_3_1 |
|
CNC(=O)NCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4376 |
EN300-1215738_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC[C@@H]5CCC(=O)NC5 |
−9.8
± 0.4
|
| 4377 |
EN300-1915260_2_2 |
|
COC[C@H](COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.8
± 0.4
|
| 4378 |
EN300-100180_1_1 |
|
CC(=O)N1CC[C@@H](C1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.5
|
| 4379 |
EN300-633533_4_1 |
|
CS(=O)(=O)[C@@H]1C[C@]1(COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C#N |
−9.8
± 0.4
|
| 4380 |
EN300-7438451_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CCn6c(nnn6)C5 |
−9.8
± 0.3
|
| 4381 |
EN300-171605_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCC5CS(=O)(=O)C5 |
−9.8
± 0.3
|
| 4382 |
EN300-31186_3_1 |
|
CCC(=O)NCCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.3
|
| 4383 |
EN300-08033_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCS(=O)(=O)C5 |
−9.8
± 0.3
|
| 4384 |
EN300-370182_2_1 |
|
Cn1c(nnn1)CCCNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.2
|
| 4385 |
EN300-1726073_2_1 |
|
Cn1c(cnn1)C(C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)(F)F |
−9.8
± 0.3
|
| 4386 |
EN300-05512_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)N[C@@H]5CCS(=O)(=O)C5 |
−9.8
± 0.5
|
| 4387 |
EN300-113633_1_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@H]5CCC(=O)NC5=O |
−9.8
± 0.3
|
| 4388 |
EN300-76451_2_4 |
|
CO[C@H]1COCC[C@H]1NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4389 |
EN300-55355_1_2 |
|
CNC(=O)[C@H]1CCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4390 |
EN300-100830_3_1 |
|
CCS(=O)(=O)N(C)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.8
± 0.4
|
| 4391 |
EN300-1709315_2_2 |
|
C[C@]1(CCCNS1(=O)=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4392 |
EN300-83827_1_1 |
|
CS(=O)(=O)[C@@H]1CSCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.3
|
| 4393 |
EN300-7445396_3_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5Cc6c[nH]cc6S5(=O)=O |
−9.8
± 0.4
|
| 4394 |
EN300-6494158_3_3 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC[C@@H]5C[C@H](CO5)CO |
−9.8
± 0.3
|
| 4395 |
EN300-6477724_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5C[C@@H]5c6[nH]cnn6 |
−9.8
± 0.4
|
| 4396 |
EN300-61898_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(nn5)n6ccnc6 |
−9.8
± 0.3
|
| 4397 |
EN300-315854_3_2 |
|
C[C@]1(CCNC(=O)C1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.8
± 0.4
|
| 4398 |
EN300-1709410_2_3 |
|
C[C@@H]1C[C@H](N1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−9.8
± 0.3
|
| 4399 |
EN300-378373_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COC5CC5 |
−9.8
± 0.2
|
| 4400 |
EN300-296237_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H](CO)C(F)(F)F |
−9.8
± 0.4
|