Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
801 |
EN300-97055_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c(=O)[nH]ccn5 |
−11.3
± 0.3
|
8.2
± 0.2
|
802 |
EN300-396748_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(c5)CO |
−11.3
± 0.3
|
8.2
± 0.2
|
803 |
EN300-214800_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCN5CCNC5=O |
−11.3
± 0.3
|
8.2
± 0.2
|
804 |
EN300-1717443_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC56CS(=O)(=O)C6 |
−11.3
± 0.3
|
8.2
± 0.2
|
805 |
EN300-27268_1
|
|
Cc1nc(on1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.3
|
8.2
± 0.2
|
806 |
EN300-6487134_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC56CC(C5)C(=O)NC6 |
−11.3
± 0.4
|
8.2
± 0.3
|
807 |
EN300-56202_3
|
|
CC(=O)N1CSCC1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.3
|
8.2
± 0.2
|
808 |
EN300-36690_1
|
|
Cn1c(=O)ccn(c1=O)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.3
|
8.2
± 0.2
|
809 |
EN300-385235_1
|
|
CC1(CCS(=O)(=O)N1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.4
|
8.2
± 0.3
|
810 |
EN300-219496_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCCN(C5)S(=O)(=O)N |
−11.3
± 0.3
|
8.2
± 0.3
|
811 |
EN300-18928_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CSCN5C(=O)C6CC6 |
−11.3
± 0.3
|
8.2
± 0.2
|
812 |
EN300-95698_3
|
|
CC1CC(=O)NCC1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.2
|
8.2
± 0.2
|
813 |
EN300-249764_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C5CCC5)O |
−11.3
± 0.3
|
8.2
± 0.2
|
814 |
EN300-65414_3
|
|
CC(=O)NC(C)(C)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.3
± 0.3
|
8.2
± 0.2
|
815 |
EN300-180532_1
|
|
CC1CN(CCS(=O)(=O)C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.3
|
8.2
± 0.2
|
816 |
EN300-2908024_1
|
|
CCC(C)(C(=O)N)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.3
± 0.3
|
8.2
± 0.2
|
817 |
EN300-83529_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nc6ncccn6n5 |
−11.3
± 0.2
|
8.2
± 0.2
|
818 |
EN300-1708882_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@@H]5COC[C@H]5O |
−11.3
± 0.2
|
8.2
± 0.2
|
819 |
DAR-DIA-5ff57136-2
|
|
C[C@H]1COc2ccc(cc2[C@@H]1C(=O)N(c3cncc4c3cccc4)C(=O)C=C)Cl |
−11.3
± 0.2
|
8.2
± 0.2
|
820 |
EN300-07268_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc6c(c5)[nH]c(=O)c(=O)[nH]6 |
−11.3
± 0.2
|
8.2
± 0.2
|
821 |
EN300-1072972_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCOC5=O |
−11.3
± 0.2
|
8.2
± 0.1
|
822 |
EN300-7463171_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCS(=O)(=O)CCO |
−11.3
± 0.6
|
8.2
± 0.5
|
823 |
EN300-261056_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(cn5)c6ncccn6 |
−11.3
± 0.2
|
8.2
± 0.1
|
824 |
EN300-35781_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc6ccccn6c5=O |
−11.3
± 0.3
|
8.2
± 0.2
|
825 |
EN300-129455_3
|
|
CCNC(=O)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.3
± 0.4
|
8.2
± 0.3
|
826 |
EN300-259187_3
|
|
CCN1CC(CCC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.4
|
8.2
± 0.3
|
827 |
EN300-13890_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CSC5CCS(=O)(=O)C5 |
−11.3
± 0.3
|
8.2
± 0.2
|
828 |
EN300-222145_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CNC(=O)N5 |
−11.3
± 0.3
|
8.2
± 0.2
|
829 |
EN300-120920_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC5CCC(=O)NC5=O |
−11.3
± 0.2
|
8.2
± 0.1
|
830 |
EN300-217343_1
|
|
Cn1c2c(nn1)CCC(C2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−11.3
± 0.3
|
8.2
± 0.2
|
831 |
EN300-128463_3
|
|
CNC(=O)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.3
± 0.3
|
8.2
± 0.2
|
832 |
EN300-222620_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cc(cnc5)O |
−11.3
± 0.3
|
8.2
± 0.2
|
833 |
EN300-633533_3
|
|
CS(=O)(=O)[C@@H]1C[C@]1(COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C#N |
−11.3
± 0.4
|
8.2
± 0.3
|
834 |
EN300-219330_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCN5CCOCC5=O |
−11.3
± 0.3
|
8.2
± 0.2
|
835 |
EN300-68203_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CCC(=O)N5 |
−11.3
± 0.2
|
8.2
± 0.2
|
836 |
EN300-249804_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCOC(=O)N5 |
−11.3
± 0.2
|
8.2
± 0.2
|
837 |
EN300-177118_1
|
|
CC1(CCC(=O)N1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.2
|
8.2
± 0.2
|
838 |
EN300-156995_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCc5c[nH]nn5 |
−11.3
± 0.4
|
8.2
± 0.3
|
839 |
EN300-1273172_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc(cn5)C(=O)N |
−11.3
± 0.2
|
8.2
± 0.2
|
840 |
EN300-33513_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CSCC(=O)N |
−11.3
± 0.3
|
8.2
± 0.2
|
841 |
EN300-82179_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC(=O)N |
−11.3
± 0.2
|
8.2
± 0.2
|
842 |
EN300-80083_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCCCC(=O)N5 |
−11.3
± 0.2
|
8.2
± 0.1
|
843 |
EN300-6482967_3
|
|
CNS(=O)(=O)CCOCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.3
± 0.4
|
8.2
± 0.3
|
844 |
EN300-44873_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCN5CCCS5(=O)=O |
−11.3
± 0.4
|
8.2
± 0.3
|
845 |
EN300-2908024_3
|
|
CCC(C)(C(=O)N)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.3
± 0.2
|
8.2
± 0.2
|
846 |
EN300-88656_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCCS5(=O)=O |
−11.3
± 0.4
|
8.2
± 0.3
|
847 |
EN300-122656_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCSC5)O |
−11.3
± 0.3
|
8.2
± 0.2
|
848 |
EN300-302058_3
|
|
CON1CCC(C1=O)OCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.3
± 0.2
|
8.2
± 0.2
|
849 |
EN300-360158_1
|
|
CC1(CC(CO1)(CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O)C |
−11.3
± 0.3
|
8.2
± 0.2
|
850 |
EN300-317555_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5=NCCO5 |
−11.3
± 0.2
|
8.2
± 0.1
|
851 |
EN300-183231_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCc5[nH]nnn5 |
−11.3
± 0.3
|
8.2
± 0.2
|
852 |
EN300-202922_3
|
|
CC(C(C)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−11.3
± 0.3
|
8.2
± 0.2
|
853 |
EN300-7436306_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5=NO[C@H]6[C@@H]5COC6 |
−11.2
± 0.3
|
8.2
± 0.2
|
854 |
EN300-221156_1
|
|
Cn1c(c2n(c1=O)CCCC2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−11.2
± 0.3
|
8.2
± 0.2
|
855 |
EN300-51244_1
|
|
Cc1cc(n(n1)C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.2
± 0.2
|
8.2
± 0.2
|
856 |
EN300-82616_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCCNC5=O |
−11.2
± 0.2
|
8.2
± 0.2
|
857 |
EN300-59487_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC(=O)NC5 |
−11.2
± 0.2
|
8.2
± 0.1
|
858 |
EN300-156995_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCc5c[nH]nn5 |
−11.2
± 0.3
|
8.2
± 0.2
|
859 |
EN300-101443_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(COC5)O |
−11.2
± 0.2
|
8.2
± 0.2
|
860 |
EN300-73967_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCS(=O)(=O)CC5)C#N |
−11.2
± 0.4
|
8.2
± 0.3
|
861 |
EN300-1091444_1
|
|
CN(C1COC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.2
± 0.3
|
8.2
± 0.2
|
862 |
EN300-123489_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(CO)(F)F |
−11.2
± 0.2
|
8.2
± 0.2
|
863 |
EN300-657211_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5[nH]c(nn5)C6CC6 |
−11.2
± 0.4
|
8.2
± 0.3
|
864 |
EN300-303519_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5OCC6 |
−11.2
± 0.2
|
8.2
± 0.2
|
865 |
EN300-51257_1
|
|
CC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−11.2
± 0.2
|
8.2
± 0.1
|
866 |
EN300-185398_4
|
|
CC(C(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(F)F)O |
−11.2
± 0.3
|
8.2
± 0.2
|
867 |
EN300-399606_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6n(n5)CCCC6O |
−11.2
± 0.2
|
8.2
± 0.1
|
868 |
EN300-135060_1
|
|
COC(=O)CSCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.2
± 0.3
|
8.2
± 0.2
|
869 |
EN300-253462_3
|
|
CN(C)C(=O)[C@@H]1C[C@@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.2
± 0.3
|
8.2
± 0.2
|
870 |
EN300-305454_1
|
|
Cn1cc(cn1)[C@@H]2CCO[C@@H]2C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−11.2
± 0.4
|
8.2
± 0.3
|
871 |
MAK-UNK-3875bbc8-2
|
|
CN(c1cncc2c1cccc2)C(=O)C3CCOc4c3cc(cc4)Cl |
−11.24
± 0.08
|
8.19
± 0.06
|
872 |
EN300-1604607_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C56CC(C5)OC6 |
−11.2
± 0.3
|
8.2
± 0.2
|
873 |
EN300-00903_1
|
|
Cc1ccnc2n1nc(n2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−11.2
± 0.3
|
8.2
± 0.2
|
874 |
EN300-90206_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CC(C5)C6O |
−11.2
± 0.3
|
8.2
± 0.2
|
875 |
EN300-28262_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc6n5ncn6 |
−11.2
± 0.3
|
8.2
± 0.2
|
876 |
EN300-30397_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)n5cncn5 |
−11.2
± 0.2
|
8.2
± 0.1
|
877 |
EN300-5638430_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CS(=O)(=O)C5 |
−11.2
± 0.3
|
8.2
± 0.2
|
878 |
EN300-224741_1
|
|
CCC(CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−11.2
± 0.2
|
8.2
± 0.1
|
879 |
EN300-7463161_4
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CCCNC(=O)[C@H]5C[C@H](C5)n6cnnc6)cc1 |
−11.2
± 0.3
|
8.2
± 0.3
|
880 |
EN300-748981_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCn6c5nnc6 |
−11.2
± 0.4
|
8.2
± 0.3
|
881 |
EN300-2007564_3
|
|
CC1(C(CCS1(=O)=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−11.2
± 0.3
|
8.2
± 0.2
|
882 |
EN300-195855_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(cn5)n6cncn6 |
−11.2
± 0.2
|
8.2
± 0.2
|
883 |
EN300-177118_3
|
|
CC1(CCC(=O)N1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.2
± 0.3
|
8.2
± 0.2
|
884 |
EN300-1387145_1
|
|
CS(=O)(=O)C1CCCC1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.2
± 0.2
|
8.2
± 0.2
|
885 |
EN300-222145_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CNC(=O)N5 |
−11.2
± 0.2
|
8.2
± 0.2
|
886 |
EN300-97661_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc[nH]c(=O)c5 |
−11.2
± 0.3
|
8.2
± 0.2
|
887 |
EN300-220194_1
|
|
CC(C(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)OC |
−11.2
± 0.2
|
8.2
± 0.1
|
888 |
EN300-179091_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC(F)F |
−11.2
± 0.2
|
8.2
± 0.2
|
889 |
EN300-649743_1
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)Cn5cnnn5 |
−11.2
± 0.4
|
8.2
± 0.3
|
890 |
EN300-1718194_1
|
|
COC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)OC |
−11.2
± 0.2
|
8.2
± 0.2
|
891 |
EN300-244947_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5c[nH]nn5 |
−11.2
± 0.3
|
8.2
± 0.2
|
892 |
EN300-6792206_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H](C5CCOCC5)O |
−11.2
± 0.4
|
8.2
± 0.3
|
893 |
EN300-50561_1
|
|
Cc1nnc2n1CC(CC2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−11.2
± 0.2
|
8.2
± 0.2
|
894 |
EN300-7542429_1
|
|
CC1CN(C2(CC2)C(=O)N1)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−11.2
± 0.2
|
8.2
± 0.2
|
895 |
EN300-204936_2
|
|
Cn1c(cnn1)C(=O)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.2
± 0.3
|
8.2
± 0.2
|
896 |
EN300-378373_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)COC5CC5 |
−11.2
± 0.3
|
8.2
± 0.2
|
897 |
EN300-102853_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc6nnnn6c5 |
−11.2
± 0.2
|
8.2
± 0.2
|
898 |
EN300-19507_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C(F)F |
−11.2
± 0.2
|
8.2
± 0.2
|
899 |
EN300-1694056_1
|
|
CC1(C(CC(=O)N1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−11.2
± 0.3
|
8.2
± 0.2
|
900 |
EN300-85413_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CC(=O)N)C5CC5 |
−11.2
± 0.2
|
8.2
± 0.1
|