Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
4701 |
EN300-384557_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(c5cnc[nH]5)O |
−9.1
± 0.2
|
6.6
± 0.2
|
4702 |
EN300-1717166_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CC56CC(C6)O |
−9.1
± 0.3
|
6.6
± 0.2
|
4703 |
EN300-257315_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCCn5cnnc5 |
−9.1
± 0.4
|
6.6
± 0.3
|
4704 |
EN300-7102031_4
|
|
COCC(CC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)COC |
−9.1
± 0.4
|
6.6
± 0.3
|
4705 |
EN300-62808_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc[nH]5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4706 |
EN300-135764_1
|
|
CC(C)(CS(=O)(=O)C)NC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.1
± 0.3
|
6.6
± 0.2
|
4707 |
EN300-57824_1
|
|
CC(Cn1cncn1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4708 |
EN300-158260_2
|
|
CC(=O)N1C[C@@H](C[C@@H]1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.1
± 0.4
|
6.6
± 0.3
|
4709 |
EN300-47606_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCC5CCS(=O)(=O)C5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4710 |
EN300-21303_2
|
|
CCOCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.1
± 0.2
|
6.6
± 0.1
|
4711 |
EN300-44014_2
|
|
COCCn1cc(ccc1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.4
|
6.6
± 0.3
|
4712 |
EN300-1722467_1
|
|
CNC(=O)C(C1(CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O)(F)F |
−9.1
± 0.3
|
6.6
± 0.2
|
4713 |
EN300-269419_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCNC(=O)N |
−9.1
± 0.2
|
6.6
± 0.1
|
4714 |
EN300-704039_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC(C56CCOCC6)O |
−9.1
± 0.2
|
6.6
± 0.2
|
4715 |
EN300-208191_3
|
|
C[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N5CCOCC5 |
−9.1
± 0.4
|
6.6
± 0.3
|
4716 |
EN300-102901_2
|
|
CCC[C@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−9.1
± 0.4
|
6.6
± 0.3
|
4717 |
EN300-1688983_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCS(=O)(=O)N6C5CCC6 |
−9.1
± 0.3
|
6.6
± 0.2
|
4718 |
EN300-172782_2
|
|
CC1C(=O)NCCCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4719 |
EN300-6499531_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCCCS5(=O)=O |
−9.1
± 0.2
|
6.6
± 0.2
|
4720 |
EN300-156963_2
|
|
CC(c1ncn(n1)C)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4721 |
EN300-225560_4
|
|
CCn1c(cnn1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.4
|
6.6
± 0.3
|
4722 |
EN300-7370063_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)CO |
−9.1
± 0.2
|
6.6
± 0.1
|
4723 |
EN300-260621_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5ccc(=O)[nH]c5 |
−9.1
± 0.3
|
6.6
± 0.3
|
4724 |
EN300-7433189_2
|
|
CC1(CN(C1)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CS(=O)(=O)C |
−9.1
± 0.3
|
6.6
± 0.2
|
4725 |
EN300-305343_2
|
|
Cn1cncc1C(CO)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4726 |
EN300-258326_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5cnccc5=O |
−9.1
± 0.3
|
6.6
± 0.2
|
4727 |
EN300-27672_2
|
|
Cc1c(cn[nH]1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4728 |
EN300-70323_2
|
|
Cc1nnc(n1C)CNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.1
|
4729 |
EN300-2666483_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cncc(n5)n6cccn6 |
−9.1
± 0.2
|
6.6
± 0.2
|
4730 |
EN300-781041_1
|
|
CC(C)(C)OC(=O)NC[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.1
± 0.3
|
6.6
± 0.2
|
4731 |
EN300-97904_2
|
|
CS(=O)(=O)CC1(CC1)CC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.4
|
6.6
± 0.3
|
4732 |
EN300-703023_1
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CC(=O)N[C@H]5C[C@@H](C5)CO)cc1 |
−9.1
± 0.3
|
6.6
± 0.2
|
4733 |
EN300-183736_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOC5)CCO |
−9.1
± 0.3
|
6.6
± 0.2
|
4734 |
EN300-36522_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)C5CC5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4735 |
EN300-224741_4
|
|
CCC(CC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.1
± 0.2
|
6.6
± 0.2
|
4736 |
EN300-76841_4
|
|
CC(COC)(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.1
± 0.4
|
6.6
± 0.3
|
4737 |
EN300-6758671_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5C[C@@H](C[C@H]5O)O |
−9.1
± 0.3
|
6.6
± 0.2
|
4738 |
EN300-260152_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cnns5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4739 |
EN300-82476_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5cnc[nH]5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4740 |
EN300-102871_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CN(C5)c6ccncn6 |
−9.1
± 0.3
|
6.6
± 0.2
|
4741 |
EN300-1179690_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(C(=O)N)(F)F |
−9.1
± 0.3
|
6.6
± 0.2
|
4742 |
EN300-124964_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCS(=O)CC5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4743 |
EN300-6746326_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCC(=O)NC5 |
−9.1
± 0.2
|
6.6
± 0.1
|
4744 |
EN300-3451857_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCC(=O)NC5=O |
−9.1
± 0.2
|
6.6
± 0.1
|
4745 |
EN300-51887_2
|
|
CNS(=O)(=O)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.1
± 0.2
|
6.6
± 0.2
|
4746 |
EN300-304381_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)CC(=O)N |
−9.1
± 0.2
|
6.6
± 0.2
|
4747 |
EN300-267219_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CC[C@@H](O5)C(=O)N6CCCC6 |
−9.1
± 0.4
|
6.6
± 0.3
|
4748 |
EN300-269628_1
|
|
Cn1c(n[nH]c1=O)CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4749 |
NAU-LAT-0543f7f2-10
|
|
CC(=O)NCCOc1cc(cc2c1OCCC2C(=O)Nc3cncc4c3cccc4)Cl |
−9.1
± 0.3
|
6.6
± 0.2
|
4750 |
EN300-1696043_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)C6COC6 |
−9.1
± 0.3
|
6.6
± 0.2
|
4751 |
EN300-211422_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4752 |
EN300-19392_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCO |
−9.1
± 0.3
|
6.6
± 0.2
|
4753 |
EN300-260816_4
|
|
CN1CCC(C1=O)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.3
|
6.6
± 0.3
|
4754 |
EN300-160277_4
|
|
COCCn1ccc(n1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4755 |
EN300-126548_1
|
|
CN1CN(CC1=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.1
|
4756 |
EN300-295372_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5ccnn5 |
−9.1
± 0.3
|
6.6
± 0.2
|
4757 |
EN300-61021_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5nnc6n5cccn6 |
−9.1
± 0.3
|
6.6
± 0.3
|
4758 |
EN300-6505003_2
|
|
CC1CCC(C(=O)N1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.1
|
4759 |
EN300-1081929_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CCS(=O)(=O)CC6C5 |
−9.1
± 0.2
|
6.6
± 0.1
|
4760 |
EN300-331993_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)Nc5[nH]ccn5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4761 |
EN300-1719160_2
|
|
CCn1cnc(n1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4762 |
EN300-112872_2
|
|
CC(C)(C)C(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NS(=O)(=O)C |
−9.1
± 0.5
|
6.6
± 0.4
|
4763 |
EN300-124063_1
|
|
Cn1c(ncn1)CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4764 |
EN300-98802_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)OCC(=O)N |
−9.1
± 0.3
|
6.6
± 0.2
|
4765 |
EN300-75030_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCC(=O)N5 |
−9.1
± 0.2
|
6.6
± 0.2
|
4766 |
ADA-UCB-dc2b944c-10
|
|
Cc1c(c2ccccc2cn1)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−9.05
± 0.10
|
6.59
± 0.07
|
4767 |
EN300-1726277_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(n5cccn5)F |
−9.1
± 0.2
|
6.6
± 0.2
|
4768 |
EN300-682529_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCOC5)CO |
−9.0
± 0.2
|
6.6
± 0.1
|
4769 |
EN300-344121_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCC[C@H]5O |
−9.0
± 0.2
|
6.6
± 0.2
|
4770 |
EN300-734638_2
|
|
COc1cc(=O)[nH]cc1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4771 |
EN300-148865_2
|
|
C[C@@H](CCO)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.0
± 0.2
|
6.6
± 0.1
|
4772 |
EN300-197801_1
|
|
COc1coc(cc1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4773 |
EN300-51071_4
|
|
CC(C)(C)NS(=O)(=O)CC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.0
± 0.3
|
6.6
± 0.2
|
4774 |
EN300-19785_2
|
|
CC(C)(CO)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.0
± 0.3
|
6.6
± 0.2
|
4775 |
EN300-6497029_1
|
|
CN(C)c1nnc(o1)CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4776 |
EN300-210552_2
|
|
CC(=O)N1CCCC(C1)(C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.0
± 0.5
|
6.6
± 0.4
|
4777 |
EN300-233678_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C(C5)CO)O |
−9.0
± 0.2
|
6.6
± 0.1
|
4778 |
EN300-58821_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN(CC5)C(=O)CO |
−9.0
± 0.3
|
6.6
± 0.2
|
4779 |
EN300-219609_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5cnccc5=O |
−9.0
± 0.3
|
6.6
± 0.2
|
4780 |
EN300-223284_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)Nc5c[nH][nH]c5=O |
−9.0
± 0.2
|
6.6
± 0.2
|
4781 |
EN300-99570_2
|
|
CN1CCC(CC1)(CCO)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.4
|
6.6
± 0.3
|
4782 |
EN300-1178014_1
|
|
COCC1(CCOCC1NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.0
± 0.5
|
6.6
± 0.4
|
4783 |
EN300-315792_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COCC(F)F |
−9.0
± 0.2
|
6.6
± 0.1
|
4784 |
EN300-1138792_4
|
|
Cn1cnnc1CCC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4785 |
EN300-156318_2
|
|
COc1cc[nH]c(=O)c1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4786 |
EN300-112500_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CC(=O)N)C5CC5 |
−9.0
± 0.2
|
6.6
± 0.2
|
4787 |
EN300-196612_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NCCF |
−9.0
± 0.2
|
6.6
± 0.2
|
4788 |
EN300-1425899_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CC[C@@H](C5)CS(=O)(=O)N |
−9.0
± 0.4
|
6.6
± 0.3
|
4789 |
EN300-264184_4
|
|
CCn1c(c[nH]c1=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4790 |
EN300-1213872_1
|
|
CN(C)[C@@H]1CN(C[C@H]1O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.2
|
6.6
± 0.2
|
4791 |
EN300-41507_2
|
|
Cc1nccn1CC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.2
|
6.6
± 0.2
|
4792 |
EN300-07676_1
|
|
c1ccc(cc1)CC(=O)NCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4793 |
EN300-318244_1
|
|
CN1CC(=O)Nc2c1ncc(c2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.0
± 0.4
|
6.6
± 0.3
|
4794 |
EN300-59970_1
|
|
Cc1nc(on1)CCNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4795 |
EN300-7463275_2
|
|
CC([C@@H]1C[C@H]1NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.0
± 0.2
|
6.6
± 0.2
|
4796 |
EN300-108305_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCOCC(=O)N |
−9.0
± 0.3
|
6.6
± 0.2
|
4797 |
EN300-381149_2
|
|
Cn1c(ncn1)C2(CN(C2)C(=O)CC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)O |
−9.0
± 0.3
|
6.6
± 0.2
|
4798 |
EN300-79588_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCCS(=O)(=O)N |
−9.0
± 0.2
|
6.6
± 0.1
|
4799 |
EN300-108171_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5COCCOC5 |
−9.0
± 0.3
|
6.6
± 0.2
|
4800 |
EN300-7437385_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5CN6CCC[C@H]6CO5 |
−9.0
± 0.4
|
6.6
± 0.3
|