Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3601 |
EN300-36850_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCNC(=O)C5CC5 |
−9.6
± 0.3
|
7.0
± 0.3
|
3602 |
EN300-41863_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c[nH]nc5 |
−9.6
± 0.2
|
7.0
± 0.1
|
3603 |
EN300-761746_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5c(=O)[nH]c(=O)[nH]n5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3604 |
EN300-6487407_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]5[C@H](CC(=O)O5)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3605 |
EN300-7549621_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5COC[C@H]5F |
−9.6
± 0.2
|
7.0
± 0.2
|
3606 |
EN300-257790_1
|
|
CCC(=O)N1CCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.3
|
3607 |
EN300-104395_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CCCO5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3608 |
EN300-6481287_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)O[C@H]5[C@@H](C[C@H]6[C@@H]5CC6=O)O |
−9.6
± 0.2
|
7.0
± 0.2
|
3609 |
DAR-DIA-0d514e7d-26
|
|
C[C@@H]1COc2c(cc(cc2OC)Cl)[C@]1(C)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.1
|
3610 |
EN300-14458_4
|
|
CC(C(=O)N(C)C)OCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
3611 |
EN300-51889_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCC(=O)N5CCC(CC5)O |
−9.6
± 0.4
|
7.0
± 0.3
|
3612 |
MAT-POS-8a69d52e-1
|
|
CC1CC(c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.61
± 0.08
|
7.00
± 0.06
|
3613 |
EN300-52009_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCC5)O |
−9.6
± 0.4
|
7.0
± 0.3
|
3614 |
EN300-7435892_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5COC[C@@H]5C(=O)N |
−9.6
± 0.2
|
7.0
± 0.2
|
3615 |
EN300-66779_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)c6[nH]nnn6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3616 |
EN300-28113_2
|
|
CC(C(=O)N1CCC(CC1)C(=O)N)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3617 |
EN300-180875_3
|
|
CN(C)C(=O)C1(CC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3618 |
EN300-269627_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)(Cn6ccnn6)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3619 |
EN300-1071940_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CCCOC5)O |
−9.6
± 0.2
|
7.0
± 0.1
|
3620 |
EN300-1703559_1
|
|
C[C@H](CS(=O)(=O)N)NC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.4
|
7.0
± 0.3
|
3621 |
EN300-266023_2
|
|
Cn1cc(nn1)CNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3622 |
EN300-66518_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)n6cncn6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3623 |
EN300-258477_2
|
|
C[C@@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−9.6
± 0.3
|
7.0
± 0.2
|
3624 |
EN300-27268_4
|
|
Cc1nc(on1)CCC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3625 |
EN300-6478433_3
|
|
CCn1c(nn(c1=O)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.6
± 0.4
|
7.0
± 0.3
|
3626 |
EN300-68882_2
|
|
CC1(C(=O)NCCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.6
± 0.3
|
7.0
± 0.2
|
3627 |
EN300-210933_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5CCN(C5)C(=O)N |
−9.6
± 0.2
|
7.0
± 0.2
|
3628 |
EN300-69811_3
|
|
Cn1cccc(c1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3629 |
EN300-716218_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCNC(=O)C56CC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3630 |
EN300-18074_2
|
|
CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.1
|
3631 |
EN300-393148_1
|
|
CN1C(CCS1(=O)=O)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3632 |
EN300-1238839_1
|
|
CS(=O)(=O)NCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.1
|
3633 |
EN300-35428_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NC5CC5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3634 |
EN300-103284_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCC5)CC(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
3635 |
EN300-260284_2
|
|
Cn1c(c[nH]c1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3636 |
EN300-378316_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5nnc6n5cc[nH]c6=O |
−9.6
± 0.3
|
7.0
± 0.2
|
3637 |
EN300-40947_3
|
|
CC(C)S(=O)(=O)C(C)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.4
|
7.0
± 0.3
|
3638 |
EN300-108430_1
|
|
C[C@@H](CNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)CO |
−9.6
± 0.3
|
7.0
± 0.2
|
3639 |
EN300-202106_2
|
|
Cn1c2c(c(ccn2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)nn1 |
−9.6
± 0.3
|
7.0
± 0.2
|
3640 |
EN300-198540_1
|
|
Cn1cc(cn1)C(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.6
± 0.2
|
7.0
± 0.2
|
3641 |
EN300-107740_1
|
|
Cc1nnn(n1)CCNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3642 |
EN300-62191_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCC(=O)NC5 |
−9.6
± 0.2
|
7.0
± 0.1
|
3643 |
EDJ-MED-e4b030d8-13
|
|
C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.60
± 0.07
|
6.99
± 0.05
|
3644 |
EN300-112872_3
|
|
CC(C)(C)C(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NS(=O)(=O)C |
−9.6
± 0.5
|
7.0
± 0.4
|
3645 |
EN300-325738_4
|
|
CN1C(CCCC1=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3646 |
EN300-52768_2
|
|
CCCS(=O)(=O)C(C)C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.6
|
7.0
± 0.4
|
3647 |
EN300-226776_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)(CO)O |
−9.6
± 0.4
|
7.0
± 0.3
|
3648 |
EN300-2723070_4
|
|
CN(C)C1COCC1OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.3
|
3649 |
EN300-7434334_2
|
|
Cn1cnc2c1ncnc2C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3650 |
EN300-04073_3
|
|
CC(=O)NCCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
3651 |
EN300-657211_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5[nH]c(nn5)C6CC6 |
−9.6
± 0.2
|
7.0
± 0.2
|
3652 |
EN300-27261_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(nc5)n6cncn6 |
−9.6
± 0.2
|
7.0
± 0.2
|
3653 |
EN300-746311_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c[nH]c6c5c(=O)[nH]cn6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3654 |
EN300-72272_2
|
|
CC(C(C)O)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.1
|
3655 |
EN300-250533_1
|
|
C[C@]1(C[C@@H](C1)NC(=O)C[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5)O |
−9.6
± 0.2
|
7.0
± 0.2
|
3656 |
EN300-6493060_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6[C@@H]([C@@H]5CO6)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3657 |
EN300-22245_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccon5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3658 |
EN300-6479181_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC6N5C(=O)CC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3659 |
EN300-74856_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCCS(=O)(=O)C5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3660 |
EN300-307592_2
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CCC(=O)N[C@H]5C[C@@H](C5)O)cc1 |
−9.6
± 0.3
|
7.0
± 0.2
|
3661 |
EN300-05512_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NC5CCS(=O)(=O)C5 |
−9.6
± 0.3
|
7.0
± 0.3
|
3662 |
EN300-83030_2
|
|
COCC(CCO)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
3663 |
EN300-98648_4
|
|
CN1CCC(C1=O)OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.1
|
3664 |
EN300-21258_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCO |
−9.6
± 0.2
|
7.0
± 0.2
|
3665 |
EN300-1277662_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5C[C@H]5CO |
−9.6
± 0.3
|
7.0
± 0.2
|
3666 |
EN300-118869_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)NC(=O)N |
−9.6
± 0.2
|
7.0
± 0.2
|
3667 |
EN300-184355_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(C(=O)N)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3668 |
EN300-67533_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(C5CC5)O |
−9.6
± 0.2
|
7.0
± 0.2
|
3669 |
EN300-7352438_4
|
|
COC[C@H]1C[C@@H]1C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3670 |
EN300-23942_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cccn5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3671 |
EN300-181558_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5(CCC(CC5)O)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3672 |
EN300-214038_2
|
|
CC(CN(CCO)C(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3673 |
EN300-262745_2
|
|
CCn1cc(nn1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3674 |
EN300-190353_1
|
|
Cc1cccc(=O)n1CC(C)(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.6
± 0.2
|
7.0
± 0.2
|
3675 |
EN300-251867_2
|
|
COCCn1cc(nn1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3676 |
EN300-6760451_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nnc6n5cccc6 |
−9.6
± 0.2
|
7.0
± 0.2
|
3677 |
EN300-1708882_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C[C@@H]5COC[C@H]5O |
−9.6
± 0.4
|
7.0
± 0.3
|
3678 |
EN300-6736413_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC5CCNC5=O |
−9.6
± 0.1
|
6.98
± 0.08
|
3679 |
EN300-68740_1
|
|
CCCNC(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
3680 |
EN300-257315_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCn5cnnc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3681 |
EN300-08063_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCC(CC5)C(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
3682 |
EN300-360158_3
|
|
CC1(CC(CO1)(CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O)C |
−9.6
± 0.3
|
7.0
± 0.2
|
3683 |
EN300-6255179_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCn5cncn5 |
−9.6
± 0.2
|
7.0
± 0.1
|
3684 |
EN300-233821_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CC5C(=O)O6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3685 |
EN300-89418_4
|
|
CC(CO)(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.4
|
7.0
± 0.3
|
3686 |
EN300-1241327_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)N5CCOCC5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3687 |
EN300-7461023_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)N(=O)=O |
−9.6
± 0.2
|
7.0
± 0.2
|
3688 |
EN300-95152_1
|
|
CN(C1CCS(=O)(=O)CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3689 |
EN300-253187_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5COCO5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3690 |
EN300-142412_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCCC(=O)N |
−9.6
± 0.4
|
7.0
± 0.3
|
3691 |
EN300-249245_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(C(F)F)O |
−9.6
± 0.2
|
7.0
± 0.2
|
3692 |
EN300-637522_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C6CCC5(CC6)C(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
3693 |
EN300-1692359_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCC5CO)CO |
−9.6
± 0.2
|
7.0
± 0.2
|
3694 |
EN300-215256_1
|
|
CC(=O)N1CCC(C1)CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3695 |
EN300-1987964_2
|
|
CS(=O)(=O)Cc1cc(no1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3696 |
EN300-378652_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)S(=O)(=O)N |
−9.6
± 0.4
|
7.0
± 0.3
|
3697 |
EN300-99391_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COC5CCOC5 |
−9.6
± 0.2
|
7.0
± 0.1
|
3698 |
EN300-97453_1
|
|
COCCCS(=O)(=O)NCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.4
|
7.0
± 0.3
|
3699 |
EN300-31562_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5c[nH]nc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3700 |
EN300-108022_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCn5cnnn5 |
−9.6
± 0.3
|
7.0
± 0.2
|