Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3501 |
EN300-1722016_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CC5)n6nccn6 |
−9.7
± 0.2
|
7.0
± 0.2
|
3502 |
EN300-783124_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(C5CCOC5)F |
−9.7
± 0.2
|
7.0
± 0.1
|
3503 |
EN300-236175_1
|
|
Cn1cc(c(=O)cc1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC |
−9.7
± 0.3
|
7.0
± 0.2
|
3504 |
EN300-69312_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@H](C5)O |
−9.7
± 0.3
|
7.0
± 0.2
|
3505 |
EN300-96808_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(CC5)OCC(=O)N |
−9.7
± 0.3
|
7.0
± 0.2
|
3506 |
EN300-383906_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)N5CCCC5 |
−9.7
± 0.4
|
7.0
± 0.3
|
3507 |
EN300-331941_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5C[C@H]5C(=O)N |
−9.7
± 0.2
|
7.0
± 0.1
|
3508 |
EN300-7430165_1
|
|
CS(=O)(=O)C[C@H]1C[C@H](C1)NC(=O)C[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3509 |
EN300-716207_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)C(CO)(F)F |
−9.7
± 0.3
|
7.0
± 0.2
|
3510 |
EN300-253462_1
|
|
CN(C)C(=O)[C@@H]1C[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3511 |
EN300-331476_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5COC[C@@H]5O |
−9.7
± 0.3
|
7.0
± 0.2
|
3512 |
EN300-6734334_1
|
|
Cc1[nH]cc(c(=O)n1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3513 |
EN300-7375395_2
|
|
CC[C@@H](C(=O)N)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.7
± 0.3
|
7.0
± 0.2
|
3514 |
EN300-68203_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCC(=O)N5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3515 |
EN300-1215712_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(COC5)O |
−9.7
± 0.3
|
7.0
± 0.2
|
3516 |
EN300-1718675_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnnn5C6CC6 |
−9.7
± 0.4
|
7.0
± 0.3
|
3517 |
EN300-103031_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6c([nH]n5)CCOC6 |
−9.7
± 0.3
|
7.0
± 0.2
|
3518 |
EN300-7442332_1
|
|
Cc1c(n(cn1)OC)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3519 |
EN300-1253122_4
|
|
CCN(C)C(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.7
± 0.2
|
7.0
± 0.1
|
3520 |
EN300-366931_2
|
|
COc1cnnc(c1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC |
−9.7
± 0.4
|
7.0
± 0.3
|
3521 |
EN300-1073320_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C5(CCC5)O)O |
−9.7
± 0.2
|
7.0
± 0.2
|
3522 |
EN300-55087_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC(C5)N6CCNC6=O |
−9.7
± 0.2
|
7.0
± 0.1
|
3523 |
EN300-7432302_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@]56CC[C@H](C5)[C@@H]([C@@H]6O)O |
−9.7
± 0.2
|
7.0
± 0.1
|
3524 |
EN300-6504498_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOCC(C5)n6cncn6 |
−9.7
± 0.3
|
7.0
± 0.2
|
3525 |
EN300-126575_2
|
|
CNC(=O)COCCNC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.7
± 0.3
|
7.0
± 0.2
|
3526 |
EN300-6739934_4
|
|
Cc1cc(nn1CCO)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3527 |
EN300-53591_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(CC5)NC(=O)N |
−9.7
± 0.3
|
7.0
± 0.2
|
3528 |
EN300-266552_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)c6[nH]cnn6 |
−9.7
± 0.3
|
7.0
± 0.2
|
3529 |
EN300-101197_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5[nH]cnn5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3530 |
EN300-1590388_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(cn5)C#N |
−9.7
± 0.3
|
7.0
± 0.2
|
3531 |
EN300-66800_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5ccc(cc5)O |
−9.7
± 0.4
|
7.0
± 0.3
|
3532 |
EN300-146174_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)CO |
−9.7
± 0.3
|
7.0
± 0.2
|
3533 |
EN300-7542465_1
|
|
CN(CC1CCCS1(=O)=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3534 |
EN300-77778_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCS(=O)(=O)C5 |
−9.7
± 0.3
|
7.0
± 0.2
|
3535 |
EN300-1709202_2
|
|
COCC(C1(CC1)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.7
± 0.5
|
7.0
± 0.3
|
3536 |
EN300-69312_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@H](C5)O |
−9.7
± 0.3
|
7.0
± 0.2
|
3537 |
EN300-51028_2
|
|
CC(C)S(=O)(=O)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.7
± 0.4
|
7.0
± 0.3
|
3538 |
EN300-7355519_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CC6C(O5)CCO6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3539 |
EN300-6487407_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC[C@@H]5[C@H](CC(=O)O5)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3540 |
EN300-116092_3
|
|
CCS(=O)(=O)NCCCOCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.5
|
7.0
± 0.4
|
3541 |
EN300-90206_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CC(C5)C6O |
−9.6
± 0.3
|
7.0
± 0.2
|
3542 |
EN300-151461_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)C6CCOC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3543 |
EN300-172870_4
|
|
COc1cncc(n1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3544 |
EN300-50488_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)OCC(F)(F)F |
−9.6
± 0.3
|
7.0
± 0.2
|
3545 |
EN300-36845_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)C5CCCC5 |
−9.6
± 0.4
|
7.0
± 0.3
|
3546 |
EN300-83280_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5ccccn5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3547 |
EN300-1440100_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC6(C5)CC(=O)NC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3548 |
EN300-22879_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCCCC5C(=O)N |
−9.6
± 0.4
|
7.0
± 0.3
|
3549 |
EN300-82181_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(=O)NCCO |
−9.6
± 0.3
|
7.0
± 0.2
|
3550 |
EN300-1629199_1
|
|
Cc1c(c(nn1C)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)N |
−9.6
± 0.4
|
7.0
± 0.3
|
3551 |
EN300-1264911_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC(CF)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3552 |
EN300-1083988_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCNC(=O)C(C5)(F)F |
−9.6
± 0.3
|
7.0
± 0.2
|
3553 |
EN300-368758_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)CC6CCCO6 |
−9.6
± 0.2
|
7.0
± 0.2
|
3554 |
EN300-1720418_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5=NOCC5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3555 |
EN300-198515_2
|
|
CC(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)n5cnc(n5)C#N |
−9.6
± 0.3
|
7.0
± 0.2
|
3556 |
EN300-102988_1
|
|
CCOC(=O)C[C@H](CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.4
|
7.0
± 0.3
|
3557 |
EN300-1215738_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCC5CCC(=O)NC5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3558 |
EN300-254105_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC(CO)C5CCCOC5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3559 |
EN300-315854_3
|
|
CC1(CCNC(=O)C1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3560 |
EN300-313366_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C56CCN(C5)CC6 |
−9.6
± 0.4
|
7.0
± 0.3
|
3561 |
EN300-37195_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NC5CCCCNC5=O |
−9.6
± 0.2
|
7.0
± 0.1
|
3562 |
EN300-1702864_2
|
|
CS(=O)(=O)C[C@@H]1C[C@@H](CN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)F |
−9.6
± 0.3
|
7.0
± 0.2
|
3563 |
EN300-6498076_1
|
|
Cc1c(c(=O)ccn1CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.6
± 0.4
|
7.0
± 0.3
|
3564 |
DAR-DIA-0d514e7d-20
|
|
C[C@H]1COc2c(cc(cc2N3CCOCC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3565 |
EN300-260760_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(=O)[nH][nH]5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3566 |
EN300-89418_3
|
|
CC(CO)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3567 |
EN300-301721_1
|
|
CC(C1CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.6
± 0.2
|
7.0
± 0.2
|
3568 |
EN300-6762327_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(Cc5ccccn5)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3569 |
EN300-87527_1
|
|
CC[C@H](C)[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
3570 |
EN300-175251_1
|
|
COCCCNC(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
3571 |
EN300-157897_2
|
|
CC[C@@H](CO)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
3572 |
EN300-1073533_4
|
|
COC1(CC(C1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C#N |
−9.6
± 0.3
|
7.0
± 0.2
|
3573 |
EN300-19515_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCC(=O)N5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3574 |
EN300-746646_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn6cc[nH]c(=O)c6n5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3575 |
EN300-6729572_2
|
|
CC(C1CC1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.6
± 0.1
|
7.0
± 0.1
|
3576 |
EN300-117430_1
|
|
C[C@H](CNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3577 |
EN300-141695_4
|
|
CN1CCC(C1=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3578 |
EN300-195790_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H](CCO)CO |
−9.6
± 0.3
|
7.0
± 0.2
|
3579 |
EN300-100700_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H](NC(=O)C5)CO |
−9.6
± 0.3
|
7.0
± 0.2
|
3580 |
EN300-393148_2
|
|
CN1C(CCS1(=O)=O)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3581 |
EN300-6763291_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC6CC5C(C6O)O |
−9.6
± 0.3
|
7.0
± 0.2
|
3582 |
EN300-247468_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC56COC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3583 |
EN300-76205_4
|
|
CC(C)(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−9.6
± 0.6
|
7.0
± 0.4
|
3584 |
EN300-7466671_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6CCO[C@]6(C5)CO |
−9.6
± 0.4
|
7.0
± 0.3
|
3585 |
EN300-1428805_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5Cc6cncn6C(=O)N5 |
−9.6
± 0.3
|
7.0
± 0.2
|
3586 |
EN300-4254263_4
|
|
Cn1ccn2c1c(cn2)C(=O)NCCC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.6
± 0.4
|
7.0
± 0.3
|
3587 |
EN300-211482_2
|
|
CC(C(=O)NC)OC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.1
|
7.01
± 0.09
|
3588 |
EN300-7353973_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC(CO)F |
−9.6
± 0.3
|
7.0
± 0.2
|
3589 |
EN300-1726150_1
|
|
Cn1cc(cn1)n2cc(nc2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.6
± 0.2
|
7.0
± 0.2
|
3590 |
DAR-DIA-0d514e7d-27
|
|
C[C@@]1(c2cc(cc(c2OCC1(C)C)OC)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.1
|
3591 |
EN300-315737_1
|
|
CSCC[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−9.6
± 0.4
|
7.0
± 0.3
|
3592 |
EN300-139167_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5COCCO5 |
−9.6
± 0.2
|
7.0
± 0.1
|
3593 |
EN300-83527_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6ncccn6n5 |
−9.6
± 0.2
|
7.0
± 0.2
|
3594 |
EN300-187998_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6(C5)CC(=O)NC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
3595 |
EN300-6497863_2
|
|
CC(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OCCN(C)C |
−9.6
± 0.6
|
7.0
± 0.4
|
3596 |
EN300-1689158_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc([nH]n5)C(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
3597 |
EN300-304187_1
|
|
CC1(CC(CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC)CO |
−9.6
± 0.2
|
7.0
± 0.2
|
3598 |
EN300-7438451_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCn6c(nnn6)C5 |
−9.6
± 0.2
|
7.0
± 0.1
|
3599 |
EN300-1865348_4
|
|
CN(C)CCOCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.6
|
7.0
± 0.5
|
3600 |
EN300-178876_4
|
|
CC1(CCCNC1=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.5
|
7.0
± 0.4
|