Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
3001 |
EN300-62574_1
|
|
Cn1c(nnn1)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.2
|
3002 |
EN300-15368_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccccc5OCC(=O)N |
−9.9
± 0.3
|
7.2
± 0.2
|
3003 |
EN300-6482967_4
|
|
CNS(=O)(=O)CCOCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.3
|
7.2
± 0.3
|
3004 |
EN300-717233_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CNCCN6S5(=O)=O |
−9.9
± 0.4
|
7.2
± 0.3
|
3005 |
EN300-378722_3
|
|
CN1CCC(C1=O)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.2
|
3006 |
EN300-373435_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5C[C@H]6CC[C@@H](C5)S6(=O)=O |
−9.9
± 0.3
|
7.2
± 0.2
|
3007 |
EN300-199290_1
|
|
Cn1c(cnn1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3008 |
EN300-76574_2
|
|
CC(CS(=O)(=O)C)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.3
|
7.2
± 0.2
|
3009 |
EN300-128431_1
|
|
Cn1c2c(cc(cn2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)nn1 |
−9.9
± 0.3
|
7.2
± 0.2
|
3010 |
EN300-1253092_1
|
|
CN(C1CCC(=O)NC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3011 |
EN300-1681046_2
|
|
Cn1c2c(c(n1)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)COCC2 |
−9.9
± 0.3
|
7.2
± 0.2
|
3012 |
EN300-203853_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNS(=O)(=O)C5CC5 |
−9.9
± 0.5
|
7.2
± 0.3
|
3013 |
EN300-36851_4
|
|
CC1CC1C(=O)NCCC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3014 |
EN300-52467_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCOCCO |
−9.9
± 0.2
|
7.2
± 0.1
|
3015 |
EN300-35592_1
|
|
Cn1cc(cc1C(=O)N)C(=O)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3016 |
EN300-84785_2
|
|
CC(CC(=O)N)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.1
|
3017 |
EN300-1699797_1
|
|
Cc1[nH]c(nn1)[C@@H](CO)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3018 |
EN300-193679_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCCOC5)O |
−9.9
± 0.2
|
7.2
± 0.2
|
3019 |
EN300-123623_1
|
|
CC(CNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−9.9
± 0.3
|
7.2
± 0.2
|
3020 |
EN300-316216_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCn5cncn5 |
−9.9
± 0.2
|
7.2
± 0.1
|
3021 |
EN300-170715_1
|
|
CC(CNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)c5nncn5C |
−9.9
± 0.3
|
7.2
± 0.2
|
3022 |
EN300-24653_1
|
|
CNC(=O)C1CCN(CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3023 |
EN300-02067_3
|
|
CC(COC)NC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.2
|
3024 |
EN300-36845_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CNC(=O)C5CCCC5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3025 |
EN300-70431_2
|
|
COc1c(c(ncn1)OC)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3026 |
EN300-248888_4
|
|
CC(C=C)(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.9
± 0.3
|
7.2
± 0.2
|
3027 |
EN300-246440_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)n6cncn6 |
−9.9
± 0.4
|
7.2
± 0.3
|
3028 |
EN300-174561_1
|
|
Cn1cncc1CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3029 |
EN300-45384_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N5CCN(CC5)C |
−9.9
± 0.4
|
7.2
± 0.3
|
3030 |
EN300-103187_4
|
|
CCOCCNC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.4
|
7.2
± 0.3
|
3031 |
EN300-101505_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CC(=O)N5 |
−9.9
± 0.2
|
7.2
± 0.1
|
3032 |
PET-UNK-29afea89-2
|
|
CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.1
|
7.20
± 0.10
|
3033 |
EN300-296237_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)C(F)(F)F |
−9.9
± 0.3
|
7.2
± 0.2
|
3034 |
MAK-UNK-83e0a0b4-1
|
|
CCCCc1ccc2c(c1)C(CCO2)C(=O)N(CCNC3CNC3)c4cncc5c4ccc(c5)CN6CCNCC6 |
−9.9
± 0.5
|
7.2
± 0.3
|
3035 |
EN300-7493197_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5ncc(c6)C(=O)N |
−9.9
± 0.3
|
7.2
± 0.2
|
3036 |
EN300-190283_2
|
|
Cn1cncc1C(C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.9
± 0.4
|
7.2
± 0.3
|
3037 |
EN300-7433125_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@]56C[C@@H]5[C@@H](C6)O |
−9.9
± 0.3
|
7.2
± 0.2
|
3038 |
EN300-36622_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5ccccc5=O |
−9.9
± 0.4
|
7.2
± 0.3
|
3039 |
EN300-384234_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(c6cnn[nH]6)O |
−9.9
± 0.3
|
7.2
± 0.2
|
3040 |
EN300-76205_2
|
|
CC(C)(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−9.9
± 0.3
|
7.2
± 0.2
|
3041 |
EN300-82037_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5ccon5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3042 |
EN300-5638430_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5CS(=O)(=O)C5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3043 |
EN300-718785_4
|
|
CCN1C(CCC1=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3044 |
EN300-117059_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CC5)CO |
−9.9
± 0.3
|
7.2
± 0.2
|
3045 |
EN300-129424_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCC5O |
−9.9
± 0.1
|
7.2
± 0.1
|
3046 |
EN300-118647_2
|
|
CN(C)C(=O)C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.3
|
7.2
± 0.2
|
3047 |
EN300-30859_2
|
|
Cn1cnnc1CNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.2
|
3048 |
EN300-25572_2
|
|
CC1CN(CCO1)C(=O)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.2
|
3049 |
EN300-151756_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6c(cn5)nc[nH]c6=O |
−9.9
± 0.3
|
7.2
± 0.2
|
3050 |
EN300-254908_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCOCC5)n6cnnn6 |
−9.9
± 0.5
|
7.2
± 0.3
|
3051 |
EN300-651177_1
|
|
C[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)Cn5cnnn5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3052 |
EN300-105482_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(COC5)CO |
−9.9
± 0.3
|
7.2
± 0.2
|
3053 |
EN300-7463171_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCS(=O)(=O)CCO |
−9.9
± 0.6
|
7.2
± 0.4
|
3054 |
EN300-1657635_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5COC[C@@H]5F |
−9.9
± 0.2
|
7.2
± 0.2
|
3055 |
EN300-122340_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCSCC5)O |
−9.9
± 0.4
|
7.2
± 0.3
|
3056 |
EN300-245036_1
|
|
C[C@H]1[C@@H](CCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
3057 |
EN300-175186_2
|
|
CC(CO)OC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.1
|
3058 |
EN300-124301_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCn5ccnn5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3059 |
EN300-39458_2
|
|
Cc1c(c(n(n1)CCO)C)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3060 |
EN300-72896_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CCC(=O)N5 |
−9.9
± 0.2
|
7.2
± 0.2
|
3061 |
EN300-120920_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC5CCC(=O)NC5=O |
−9.9
± 0.2
|
7.2
± 0.1
|
3062 |
EN300-39501_2
|
|
COCCS(=O)(=O)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.4
|
7.2
± 0.3
|
3063 |
EN300-68794_3
|
|
CS(=O)(=O)CCCOCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.2
|
3064 |
EN300-321053_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CCOCC5O |
−9.9
± 0.2
|
7.2
± 0.1
|
3065 |
EN300-313440_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CN(C5)C6CCOCC6 |
−9.9
± 0.6
|
7.2
± 0.4
|
3066 |
EN300-1073264_4
|
|
Cn1cc(nn1)CC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3067 |
EN300-6493060_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]6[C@@H]([C@@H]5CO6)O |
−9.9
± 0.3
|
7.2
± 0.2
|
3068 |
EN300-7412943_2
|
|
CC1(CN(C[C@@H](O1)CO)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−9.9
± 0.4
|
7.2
± 0.3
|
3069 |
EN300-135238_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5[nH]cc6 |
−9.9
± 0.3
|
7.2
± 0.2
|
3070 |
EN300-132523_1
|
|
CN(CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−9.9
± 0.3
|
7.2
± 0.2
|
3071 |
EN300-343103_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5[nH]c(=O)c6c(n5)CCOC6 |
−9.9
± 0.4
|
7.2
± 0.3
|
3072 |
EN300-1073264_3
|
|
Cn1cc(nn1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3073 |
EN300-331704_1
|
|
C[C@H]1CN(CCS1(=O)=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3074 |
EN300-6481287_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCO[C@H]5[C@@H](C[C@H]6[C@@H]5CC6=O)O |
−9.9
± 0.3
|
7.2
± 0.2
|
3075 |
EN300-305996_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5COC(=O)N5 |
−9.9
± 0.2
|
7.2
± 0.1
|
3076 |
EN300-18557_1
|
|
CC(=O)N1CCC(CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3077 |
EN300-75819_1
|
|
CCN(CC)S(=O)(=O)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.4
|
7.2
± 0.3
|
3078 |
EN300-21258_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCO |
−9.9
± 0.2
|
7.2
± 0.1
|
3079 |
EN300-2690393_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(cnc5)n6cnnn6 |
−9.9
± 0.4
|
7.2
± 0.3
|
3080 |
EN300-264301_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H]5CCC(=O)N5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3081 |
EN300-7427921_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)n6cnnc6 |
−9.9
± 0.3
|
7.2
± 0.2
|
3082 |
EN300-6498888_1
|
|
CC(COC1CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
3083 |
EN300-45182_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCCN5CCOC5=O |
−9.9
± 0.4
|
7.2
± 0.3
|
3084 |
EN300-206646_2
|
|
CS(=O)(=O)c1cncc(n1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.3
|
3085 |
EN300-173006_4
|
|
CC(c1nnnn1C)OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3086 |
EN300-37022_3
|
|
Cc1c(c(=O)[nH]c(n1)C)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3087 |
EN300-52467_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCOCCO |
−9.9
± 0.1
|
7.2
± 0.1
|
3088 |
EN300-100180_3
|
|
CC(=O)N1CCC(C1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3089 |
EN300-48760_1
|
|
CC(C)(C)NC(=O)CNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.3
|
7.2
± 0.2
|
3090 |
EN300-17381_2
|
|
CC(C(=O)N)OC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.86
± 0.09
|
7.18
± 0.07
|
3091 |
EN300-227044_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CO)C#N |
−9.9
± 0.3
|
7.2
± 0.2
|
3092 |
EN300-246747_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5CC(=O)NC5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3093 |
EN300-23317_2
|
|
CC(C(=O)NCCOC)OC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.5
|
7.2
± 0.3
|
3094 |
EN300-6766760_1
|
|
CCn1cnnc1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.2
|
3095 |
EN300-124457_2
|
|
CN(C)Cc1cc(no1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3096 |
EN300-132624_1
|
|
CCC(=O)CNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.3
|
7.2
± 0.2
|
3097 |
EN300-359750_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CCC(=O)O5 |
−9.9
± 0.2
|
7.2
± 0.2
|
3098 |
EN300-39305_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCS(=O)(=O)CC5 |
−9.9
± 0.4
|
7.2
± 0.3
|
3099 |
EN300-1600786_4
|
|
Cn1cc(nn1)CCOCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
3100 |
EN300-113633_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCC(=O)NC5=O |
−9.9
± 0.2
|
7.2
± 0.1
|