Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2901 |
EN300-91905_1
|
|
C[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.0
± 0.2
|
7.3
± 0.1
|
2902 |
EN300-54541_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5CCC(=O)N5 |
−10.0
± 0.3
|
7.3
± 0.2
|
2903 |
EN300-224665_1
|
|
CC1(CN(CCOC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.0
± 0.3
|
7.3
± 0.2
|
2904 |
EN300-196320_1
|
|
CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.3
|
7.3
± 0.2
|
2905 |
EN300-31969_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CC(=O)N(C5)CC6CC6 |
−10.0
± 0.3
|
7.3
± 0.2
|
2906 |
EN300-67023_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CS(=O)(=O)CC5CCCO5 |
−10.0
± 0.4
|
7.3
± 0.3
|
2907 |
DAR-DIA-0d514e7d-15
|
|
C[C@H]1COc2c(cc(cc2[C@@H]1C(=O)Nc3cncc4c3cccc4)Cl)c5cc(ccc5F)F |
−10.0
± 0.2
|
7.3
± 0.2
|
2908 |
EN300-124457_1
|
|
CN(C)Cc1cc(no1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.3
|
7.3
± 0.2
|
2909 |
EN300-263085_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CC5)n6cnnn6 |
−10.0
± 0.3
|
7.3
± 0.2
|
2910 |
EN300-188377_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc6c5[nH]nn6 |
−10.0
± 0.3
|
7.3
± 0.2
|
2911 |
EN300-67791_1
|
|
CC(C)C1C(=O)NCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.3
|
7.3
± 0.2
|
2912 |
EN300-264301_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]5CCC(=O)N5 |
−10.0
± 0.2
|
7.3
± 0.2
|
2913 |
EN300-6482967_1
|
|
CNS(=O)(=O)CCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.0
± 0.3
|
7.3
± 0.2
|
2914 |
EN300-248374_2
|
|
CCO[C@@H]1COC[C@H]1NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.3
|
7.3
± 0.2
|
2915 |
EN300-178288_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CC6(C5)O |
−10.0
± 0.3
|
7.3
± 0.2
|
2916 |
EN300-87334_2
|
|
Cn1c(ncn1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.2
|
7.3
± 0.2
|
2917 |
EN300-226486_2
|
|
CCn1ncc(n1)CNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.2
|
7.3
± 0.2
|
2918 |
EN300-6745214_1
|
|
CON=C1CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.2
|
7.2
± 0.2
|
2919 |
EN300-125143_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCCCC(=O)N |
−10.0
± 0.3
|
7.2
± 0.2
|
2920 |
DAR-DIA-6a508060-10
|
|
CC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.0
± 0.1
|
7.25
± 0.07
|
2921 |
EN300-52983_3
|
|
CN1CC(CCC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.0
± 0.3
|
7.2
± 0.2
|
2922 |
EN300-21409_2
|
|
C#CCNC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.1
|
2923 |
EN300-332002_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCc6n5c(=O)ccc6 |
−9.9
± 0.2
|
7.2
± 0.2
|
2924 |
EN300-2924757_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(cc5)CC(=O)N |
−9.9
± 0.3
|
7.2
± 0.2
|
2925 |
EN300-194132_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6COCC(C5)O6 |
−9.9
± 0.3
|
7.2
± 0.2
|
2926 |
EN300-198633_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCCCNC5=O |
−9.9
± 0.3
|
7.2
± 0.2
|
2927 |
EN300-53423_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCOC5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2928 |
EN300-69070_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CC5)C(=O)N |
−9.9
± 0.3
|
7.2
± 0.2
|
2929 |
EN300-65063_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCN(CC5)C(=O)N |
−9.9
± 0.4
|
7.2
± 0.3
|
2930 |
EN300-7445890_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC6(C5)C(CC6O)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2931 |
EN300-202922_1
|
|
CC(C(C)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−9.9
± 0.2
|
7.2
± 0.2
|
2932 |
EN300-383904_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCNC(=O)CO |
−9.9
± 0.3
|
7.2
± 0.2
|
2933 |
EN300-1709295_3
|
|
Cc1cnc(cn1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.4
|
7.2
± 0.3
|
2934 |
EN300-746122_2
|
|
COC[C@H](CNC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2935 |
EN300-1452069_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(CC5CCOCC5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2936 |
EN300-260152_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cnns5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2937 |
EN300-216594_2
|
|
Cn1cncc1CNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.1
|
2938 |
EN300-1268016_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC6C5CC(C6)C(=O)N |
−9.9
± 0.2
|
7.2
± 0.1
|
2939 |
EN300-331993_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)Nc5[nH]ccn5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2940 |
EN300-210552_1
|
|
CC(=O)N1CCCC(C1)(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2941 |
EN300-300519_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5csnn5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2942 |
EN300-7448078_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6(CC5)C(CC6O)O |
−9.9
± 0.2
|
7.2
± 0.2
|
2943 |
EN300-392656_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5C[C@H]([C@H](C5)O)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2944 |
EN300-866702_4
|
|
C=CCOC(=O)NCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.3
|
7.2
± 0.2
|
2945 |
EN300-132615_4
|
|
CC(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−9.9
± 0.4
|
7.2
± 0.3
|
2946 |
EN300-39305_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCS(=O)(=O)CC5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2947 |
EN300-2008120_2
|
|
C[C@H]1[C@H](CCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.9
± 0.2
|
7.2
± 0.1
|
2948 |
EN300-262204_4
|
|
CS(=O)(=O)CC1(COC1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.3
|
2949 |
EN300-227055_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CC(=O)NC5=O |
−9.9
± 0.3
|
7.2
± 0.2
|
2950 |
MAK-UNK-8be7dca9-4
|
|
c1cc2cncc(c2cc1N3CCNCC3)NC(=O)C4CCOc5c4cc(cc5)Cl |
−9.94
± 0.09
|
7.24
± 0.06
|
2951 |
JOH-UNI-f51e3bbc-4
|
|
COc1c(c2ccccc2cn1)NC(=O)C3CCOc4c3cc(cc4)Cl |
−9.9
± 0.1
|
7.24
± 0.10
|
2952 |
EN300-04492_2
|
|
COCCCNC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.4
|
7.2
± 0.3
|
2953 |
EN300-1911992_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(C5CCOC5)O |
−9.9
± 0.2
|
7.2
± 0.2
|
2954 |
EN300-31037_1
|
|
Cn1c2c(c(=O)n(c1=O)C)[nH]c(n2)CO[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.9
± 0.3
|
7.2
± 0.2
|
2955 |
EN300-154229_1
|
|
C[C@H](CN1CCN(CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.9
± 0.4
|
7.2
± 0.3
|
2956 |
EN300-113218_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CSC5CCOC5=O |
−9.9
± 0.3
|
7.2
± 0.2
|
2957 |
EN300-94856_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CC(C5)O |
−9.9
± 0.2
|
7.2
± 0.2
|
2958 |
EN300-7443878_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H](C5CCOCC5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2959 |
EN300-7432022_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C56CCN(C5)S(=O)(=O)C6 |
−9.9
± 0.4
|
7.2
± 0.3
|
2960 |
EN300-20284_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCCC(C5)O |
−9.9
± 0.2
|
7.2
± 0.2
|
2961 |
EN300-7493922_1
|
|
Cn1cnc(n1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2962 |
EN300-321790_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@@H]6C[C@H]5CO6 |
−9.9
± 0.3
|
7.2
± 0.2
|
2963 |
EN300-366540_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CCOC[C@H]5O |
−9.9
± 0.2
|
7.2
± 0.2
|
2964 |
EN300-385235_3
|
|
CC1(CCS(=O)(=O)N1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.4
|
7.2
± 0.3
|
2965 |
EN300-07879_2
|
|
CSCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.2
|
2966 |
EN300-207873_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CC5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2967 |
EN300-1091496_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCN6C(C5)CCS6(=O)=O |
−9.9
± 0.2
|
7.2
± 0.1
|
2968 |
EN300-396146_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CO)CO |
−9.9
± 0.3
|
7.2
± 0.2
|
2969 |
EN300-69162_4
|
|
CC(COC)C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.2
|
2970 |
EN300-88656_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCS5(=O)=O |
−9.9
± 0.2
|
7.2
± 0.2
|
2971 |
EN300-30768_3
|
|
CC1CC1C(=O)NCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.1
|
2972 |
EN300-58433_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(c5)n6cncn6 |
−9.9
± 0.4
|
7.2
± 0.3
|
2973 |
EN300-118647_1
|
|
CN(C)C(=O)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.2
|
2974 |
EN300-685492_1
|
|
COCc1[nH]c(=O)c(cn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.3
|
2975 |
EN300-6974806_4
|
|
C[C@H]([C@@H](C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−9.9
± 0.4
|
7.2
± 0.3
|
2976 |
EN300-18928_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CSCN5C(=O)C6CC6 |
−9.9
± 0.4
|
7.2
± 0.3
|
2977 |
EN300-92790_3
|
|
Cn1ccc(n1)CCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2978 |
EN300-54304_4
|
|
CCOCCOCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.4
|
7.2
± 0.3
|
2979 |
EN300-107435_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCCCS5(=O)=O |
−9.9
± 0.2
|
7.2
± 0.1
|
2980 |
EN300-6493972_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@]56C[C@H]5[C@@H](C6)O |
−9.9
± 0.4
|
7.2
± 0.3
|
2981 |
EN300-250416_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nc6ncccn6n5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2982 |
EN300-04073_1
|
|
CC(=O)NCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.2
|
2983 |
EN300-98429_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5c[nH]nn5 |
−9.9
± 0.2
|
7.2
± 0.2
|
2984 |
EN300-223491_2
|
|
Cn1cnn(c1=O)CCC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2985 |
EN300-87334_4
|
|
Cn1c(ncn1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2986 |
EN300-101291_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(c(=O)[nH]c5=O)CCO |
−9.9
± 0.4
|
7.2
± 0.3
|
2987 |
EN300-22245_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5ccon5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2988 |
EN300-7435400_3
|
|
C[C@@H]1C[C@@H](CC(=O)N1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2989 |
EN300-6499164_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(=O)NC6C5CC6 |
−9.9
± 0.3
|
7.2
± 0.2
|
2990 |
EN300-1589101_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5c[nH]nc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2991 |
EN300-103979_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6c(nc5)OCC(=O)N6 |
−9.9
± 0.3
|
7.2
± 0.2
|
2992 |
EN300-25702_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CC5)O |
−9.9
± 0.3
|
7.2
± 0.2
|
2993 |
EN300-299532_1
|
|
CC(C)(C(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−9.9
± 0.2
|
7.2
± 0.1
|
2994 |
EN300-76584_1
|
|
Cc1c(cn(n1)C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.2
|
7.2
± 0.2
|
2995 |
EN300-124904_1
|
|
Cn1c(nnn1)CCNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2996 |
EN300-1272529_1
|
|
CN(C)C(=O)OC1CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.9
± 0.3
|
7.2
± 0.2
|
2997 |
EN300-49064_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5COC5 |
−9.9
± 0.2
|
7.2
± 0.2
|
2998 |
EN300-1726153_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccn6c5nnc6 |
−9.9
± 0.3
|
7.2
± 0.2
|
2999 |
EN300-54304_3
|
|
CCOCCOCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.3
|
7.2
± 0.2
|
3000 |
EN300-23648_2
|
|
C[C@@H](C(=O)N)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.9
± 0.2
|
7.2
± 0.1
|