Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2601 |
EN300-371704_2
|
|
C[C@@H]1CS(=O)(=O)C[C@@H]1NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.4
± 0.2
|
2602 |
EN300-16091_1
|
|
CCS(=O)(=O)N1CCCC1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.4
|
7.4
± 0.3
|
2603 |
EN300-1720418_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5=NOCC5 |
−10.1
± 0.2
|
7.4
± 0.1
|
2604 |
EN300-262389_1
|
|
C[C@]1(CC[C@H]1NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.1
± 0.3
|
7.4
± 0.2
|
2605 |
EN300-36390_1
|
|
CCOC(=O)NCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.2
|
7.4
± 0.2
|
2606 |
EN300-61021_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnc6n5cccn6 |
−10.1
± 0.3
|
7.4
± 0.2
|
2607 |
EN300-332601_2
|
|
CCC(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−10.1
± 0.3
|
7.4
± 0.2
|
2608 |
EN300-208204_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H](CO)C(=O)N |
−10.1
± 0.3
|
7.4
± 0.2
|
2609 |
EN300-60862_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC(C5)C(=O)N |
−10.1
± 0.2
|
7.4
± 0.1
|
2610 |
EN300-29228_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCn6c(cnn6)C5 |
−10.1
± 0.3
|
7.4
± 0.2
|
2611 |
EN300-7439985_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(CC5C6)CO |
−10.1
± 0.2
|
7.4
± 0.2
|
2612 |
EN300-111006_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccncn5 |
−10.1
± 0.2
|
7.4
± 0.2
|
2613 |
EN300-861925_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC(CO)F |
−10.1
± 0.3
|
7.4
± 0.2
|
2614 |
EN300-6477475_1
|
|
COCc1cc(no1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.4
± 0.2
|
2615 |
EN300-862094_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC5C(=O)N |
−10.1
± 0.2
|
7.4
± 0.2
|
2616 |
EN300-37077_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccn[nH]5 |
−10.1
± 0.2
|
7.4
± 0.2
|
2617 |
EN300-39405_1
|
|
CC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−10.1
± 0.2
|
7.4
± 0.2
|
2618 |
EN300-131093_1
|
|
CC(C(=O)NCC(=O)C)O[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.2
|
7.4
± 0.2
|
2619 |
EN300-12587_3
|
|
CC(=O)N1CCCC1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.4
± 0.2
|
2620 |
EN300-158207_1
|
|
Cc1nnc(o1)[C@H]2C[C@H](CN2C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)O |
−10.1
± 0.4
|
7.4
± 0.3
|
2621 |
EN300-188217_1
|
|
CC(C)(CS(=O)(=O)C)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.4
± 0.2
|
2622 |
EN300-7457159_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5cc(on5)C6(COC6)O |
−10.1
± 0.3
|
7.4
± 0.2
|
2623 |
EN300-158067_1
|
|
Cc1c(c(n(n1)C)n2cncn2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.1
± 0.2
|
7.4
± 0.2
|
2624 |
EN300-380827_1
|
|
Cn1c(cnn1)C2(CN(C2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)OC |
−10.1
± 0.4
|
7.4
± 0.3
|
2625 |
EN300-702735_1
|
|
c1ccc(cc1)c2nnnn2CC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.1
± 0.3
|
7.4
± 0.2
|
2626 |
EN300-325737_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6ccccn6nn5 |
−10.1
± 0.2
|
7.4
± 0.2
|
2627 |
EN300-31242_1
|
|
COCC(=O)NCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.4
± 0.2
|
2628 |
EN300-12204_3
|
|
CCCNC(=O)CN(C)C(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.4
|
7.4
± 0.3
|
2629 |
EN300-1706036_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5C(=O)NCCO5 |
−10.1
± 0.2
|
7.4
± 0.2
|
2630 |
EN300-66432_3
|
|
CN(C)S(=O)(=O)CCCOCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.4
|
7.4
± 0.3
|
2631 |
EN300-23019_2
|
|
CC(C)(C)NC(=O)CN(C)C(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.4
± 0.3
|
2632 |
EN300-105110_1
|
|
Cc1cc(n[nH]1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.4
± 0.2
|
2633 |
EN300-6766359_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5[C@H]6C[C@H]6C(=O)N5 |
−10.1
± 0.3
|
7.4
± 0.2
|
2634 |
EN300-14395_1
|
|
Cn1cc(cn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.2
|
7.4
± 0.2
|
2635 |
EN300-22880_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)N5CCCC(C5)C(=O)N |
−10.1
± 0.2
|
7.4
± 0.2
|
2636 |
EN300-7444316_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]([C@@H](C5)C(=O)N)C(=O)N |
−10.1
± 0.4
|
7.4
± 0.3
|
2637 |
EN300-137734_1
|
|
CC1CN(CCS1(=O)=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.4
± 0.2
|
2638 |
EN300-89418_1
|
|
CC(CO)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.1
± 0.5
|
7.4
± 0.4
|
2639 |
EN300-119126_3
|
|
Cc1[nH]c(nn1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.4
|
7.3
± 0.3
|
2640 |
EN300-1915260_2
|
|
COCC(COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.1
± 0.3
|
7.3
± 0.2
|
2641 |
EN300-75674_2
|
|
Cc1c(non1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2642 |
EN300-27268_3
|
|
Cc1nc(on1)CCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2643 |
EN300-45182_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCN5CCOC5=O |
−10.1
± 0.3
|
7.3
± 0.3
|
2644 |
EN300-385267_3
|
|
COC1(CCS(=O)(=O)C1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2645 |
EN300-82616_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCNC5=O |
−10.1
± 0.2
|
7.3
± 0.2
|
2646 |
EN300-39101_1
|
|
CCOC(=O)N(C)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.3
± 0.2
|
2647 |
EN300-08063_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)N5CCC(CC5)C(=O)N |
−10.1
± 0.3
|
7.3
± 0.2
|
2648 |
EN300-70522_1
|
|
CS(=O)(=O)CCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.3
± 0.2
|
2649 |
EN300-132615_2
|
|
CC(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−10.1
± 0.3
|
7.3
± 0.2
|
2650 |
EN300-132624_2
|
|
CCC(=O)CNC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.4
|
7.3
± 0.3
|
2651 |
EN300-379533_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)O |
−10.1
± 0.2
|
7.3
± 0.1
|
2652 |
EN300-23792_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(sc5)S(=O)(=O)N |
−10.1
± 0.3
|
7.3
± 0.2
|
2653 |
EN300-11195_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)N5CCC5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2654 |
EN300-79536_2
|
|
C=CCN(CCO)C(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.2
|
7.3
± 0.2
|
2655 |
EN300-131093_4
|
|
CC(C(=O)NCC(=O)C)OCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.4
|
7.3
± 0.3
|
2656 |
EN300-302058_2
|
|
CON1CCC(C1=O)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.2
|
7.3
± 0.2
|
2657 |
EN300-67573_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NC5CCOCC5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2658 |
EN300-222969_2
|
|
CN1CC(OC1=O)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2659 |
EN300-19242_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CO |
−10.1
± 0.2
|
7.3
± 0.1
|
2660 |
EN300-182725_4
|
|
CC(C(C)S(=O)(=O)C)C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.3
± 0.2
|
2661 |
EN300-2855057_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)N5CCOCC5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2662 |
EN300-239219_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nc(no5)c6cnccn6 |
−10.1
± 0.2
|
7.3
± 0.1
|
2663 |
EN300-31099_4
|
|
CCC(=O)NCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.4
|
7.3
± 0.3
|
2664 |
EN300-141480_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCCN(C5=O)CCO |
−10.1
± 0.4
|
7.3
± 0.3
|
2665 |
EN300-106781_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5ccc(=O)[nH]c5=O |
−10.1
± 0.4
|
7.3
± 0.3
|
2666 |
EN300-263346_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5c(=O)n6c(n5)CCCC6 |
−10.1
± 0.4
|
7.3
± 0.3
|
2667 |
EN300-36851_1
|
|
CC1CC1C(=O)NCCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.2
|
7.3
± 0.2
|
2668 |
EN300-92633_1
|
|
Cn1cc(cn1)N2CC(CC2=O)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.1
± 0.3
|
7.3
± 0.2
|
2669 |
EN300-6792206_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H](C5CCOCC5)O |
−10.1
± 0.3
|
7.3
± 0.2
|
2670 |
EN300-188585_1
|
|
CC1(CCS(=O)(=O)CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2671 |
JAG-UCB-706446eb-6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccn[nH]5 |
−10.1
± 0.2
|
7.3
± 0.2
|
2672 |
EN300-315836_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5[nH]ccn5 |
−10.1
± 0.2
|
7.3
± 0.2
|
2673 |
EN300-1609922_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)(c6ccn[nH]6)O |
−10.1
± 0.3
|
7.3
± 0.2
|
2674 |
EN300-6479892_1
|
|
CN1C(=O)COC12CCN(CC2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.1
± 0.3
|
7.3
± 0.2
|
2675 |
EN300-77885_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)C5CC5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2676 |
EN300-219802_2
|
|
Cn1cnc2c1c(cc(=O)[nH]2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.1
± 0.3
|
7.3
± 0.2
|
2677 |
EN300-6486855_3
|
|
Cn1c(cnn1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.2
|
7.3
± 0.2
|
2678 |
EN300-37529_1
|
|
Cc1cc(n2c(n1)nc(n2)CC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)C |
−10.1
± 0.3
|
7.3
± 0.2
|
2679 |
MAK-UNK-8be7dca9-5
|
|
c1cc2c(cc1CN)cncc2NC(=O)C3CCOc4c3cc(cc4)Cl |
−10.07
± 0.08
|
7.33
± 0.06
|
2680 |
EN300-07879_4
|
|
CSCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.3
± 0.2
|
2681 |
EN300-44821_4
|
|
C=CCOCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.4
|
7.3
± 0.3
|
2682 |
EN300-45049_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCS(=O)(=O)N5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2683 |
EN300-1627945_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)COC5CCCOC5 |
−10.1
± 0.4
|
7.3
± 0.3
|
2684 |
EN300-7493296_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H]6[C@H]5COC6 |
−10.1
± 0.3
|
7.3
± 0.2
|
2685 |
EN300-154168_1
|
|
COCCN1CCCN(CC1=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2686 |
EN300-86732_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCNC(=O)C5CCCO5 |
−10.1
± 0.2
|
7.3
± 0.2
|
2687 |
EN300-31147_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCNC(=O)C5CC5 |
−10.1
± 0.4
|
7.3
± 0.3
|
2688 |
EN300-129455_2
|
|
CCNC(=O)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.1
± 0.3
|
7.3
± 0.2
|
2689 |
EN300-1721883_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CC5)n6ccnn6 |
−10.1
± 0.3
|
7.3
± 0.2
|
2690 |
EN300-6737762_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCCNC5=O |
−10.1
± 0.2
|
7.3
± 0.2
|
2691 |
EN300-19392_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCO |
−10.1
± 0.3
|
7.3
± 0.2
|
2692 |
EN300-1272704_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CCO[C@@H]5c6[nH]cnn6 |
−10.1
± 0.4
|
7.3
± 0.3
|
2693 |
EN300-80522_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COCC5CCOC5 |
−10.1
± 0.2
|
7.3
± 0.2
|
2694 |
EN300-1723498_4
|
|
CCc1c(non1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.4
|
7.3
± 0.3
|
2695 |
EN300-332606_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H]5CCC(=O)O5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2696 |
EN300-212365_1
|
|
Cn1cnnc1CN(C)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2697 |
EN300-01527_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCC5CCCO5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2698 |
EN300-20160_1
|
|
CC(CNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.1
± 0.2
|
7.3
± 0.2
|
2699 |
EN300-182084_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)c5cscn5 |
−10.1
± 0.3
|
7.3
± 0.2
|
2700 |
EN300-311920_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5(CCS(=O)(=O)C5)F |
−10.1
± 0.3
|
7.3
± 0.2
|