Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2401 |
EN300-60837_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc6nncn6c5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2402 |
EN300-2977549_1
|
|
CNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.1
|
7.45
± 0.08
|
2403 |
EN300-83280_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)c5ccccn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2404 |
EN300-697519_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCOC5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2405 |
EN300-1915260_4
|
|
COCC(COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2406 |
EN300-2923949_3
|
|
c1ccc(cc1)C(C(C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O)O |
−10.2
± 0.4
|
7.4
± 0.3
|
2407 |
EN300-96544_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5[nH]c(=O)[nH]n5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2408 |
EN300-146051_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc(nc5)CO |
−10.2
± 0.3
|
7.4
± 0.2
|
2409 |
EN300-317555_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5=NCCO5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2410 |
EN300-92656_1
|
|
Cc1cnc2nc(nn2c1)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.2
± 0.3
|
7.4
± 0.2
|
2411 |
EN300-41863_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c[nH]nc5 |
−10.2
± 0.2
|
7.4
± 0.1
|
2412 |
EN300-6764836_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC6C(C(C5O6)O)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2413 |
EN300-103219_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CC(=O)N5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2414 |
EN300-36111_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCCCC5=O |
−10.2
± 0.3
|
7.4
± 0.2
|
2415 |
EN300-36089_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)c5ccncc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2416 |
EN300-127487_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC(=O)NC5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2417 |
EN300-31185_1
|
|
CC(C)C(=O)NCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2418 |
EN300-67073_3
|
|
CC(=O)NC(C)(C1CC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2419 |
EN300-123205_2
|
|
CNS(=O)(=O)CCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2420 |
EN300-245061_3
|
|
Cc1c(cn(n1)C)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2421 |
EN300-134536_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5ccnn5CCO |
−10.2
± 0.3
|
7.4
± 0.2
|
2422 |
EN300-77343_1
|
|
Cc1nnnn1CCNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2423 |
EN300-1073264_2
|
|
Cn1cc(nn1)CC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2424 |
EN300-1178005_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(on5)C#N |
−10.2
± 0.3
|
7.4
± 0.2
|
2425 |
EN300-254840_1
|
|
CC(C1CN(CCO1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2426 |
EN300-66082_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C5CCC5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2427 |
EN300-1587757_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCNS5(=O)=O |
−10.2
± 0.3
|
7.4
± 0.2
|
2428 |
EN300-731622_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5COCCO5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2429 |
EN300-2011576_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5Cc6c(nccn6)C5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2430 |
EN300-47606_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCC5CCS(=O)(=O)C5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2431 |
EN300-259694_1
|
|
CCOC1(CCOC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2432 |
EN300-62166_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCCC5CNC(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|
2433 |
EN300-205110_1
|
|
C[C@H](CO)N(C)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2434 |
EN300-381149_1
|
|
Cn1c(ncn1)C2(CN(C2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2435 |
EN300-18569_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−10.2
± 0.2
|
7.4
± 0.1
|
2436 |
EN300-7443878_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H](C5CCOCC5)O |
−10.2
± 0.4
|
7.4
± 0.3
|
2437 |
EN300-53918_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCN5CCOC5=O |
−10.2
± 0.3
|
7.4
± 0.2
|
2438 |
EN300-2008240_2
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CNC(=O)[C@H]5C[C@@H](C5)n6nncc6)cc1 |
−10.2
± 0.3
|
7.4
± 0.2
|
2439 |
EN300-384027_1
|
|
COC(=O)[C@@H]1C[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2440 |
EN300-77092_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5OCCO5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2441 |
EN300-749499_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(C5(CCOCC5)O)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2442 |
EN300-785910_4
|
|
COCc1c(nn[nH]1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2443 |
EN300-7534935_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CCC(=O)O6 |
−10.2
± 0.3
|
7.4
± 0.2
|
2444 |
EN300-238234_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6c([nH]c5=O)CCCC6O |
−10.2
± 0.3
|
7.4
± 0.2
|
2445 |
EN300-174668_4
|
|
COC1(CCOC1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.5
|
7.4
± 0.4
|
2446 |
EN300-250836_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5c[nH]nc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2447 |
EN300-39961_1
|
|
CCN1CCN(C(=O)C1=O)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2448 |
EN300-69556_1
|
|
Cc1ccc(=O)n(n1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.3
|
2449 |
EN300-60330_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6C(C5)CCC6=O |
−10.2
± 0.3
|
7.4
± 0.2
|
2450 |
EN300-19542_2
|
|
CC(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.2
|
7.4
± 0.1
|
2451 |
EN300-30419_4
|
|
CS(=O)(=O)NCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2452 |
EN300-210110_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)C6CC6 |
−10.2
± 0.2
|
7.4
± 0.2
|
2453 |
EN300-7457160_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5=NOC(C5)CC6(COC6)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2454 |
EN300-19709_1
|
|
CCC(CO)NC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2455 |
EN300-7349829_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(=O)NCC56CCC6 |
−10.2
± 0.3
|
7.4
± 0.2
|
2456 |
BEN-BAS-5c03e89e-1
|
|
CC(C)(C1COc2ccc(cc2C1C(=O)Nc3cncc4c3cccc4)Cl)O |
−10.2
± 0.1
|
7.43
± 0.07
|
2457 |
EN300-233079_1
|
|
Cc1cnn(c1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.2
± 0.3
|
7.4
± 0.2
|
2458 |
EN300-76387_2
|
|
CC(Cc1[nH]nnn1)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2459 |
EN300-1699871_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5CCS(=O)(=O)N5 |
−10.2
± 0.2
|
7.4
± 0.1
|
2460 |
EN300-6472952_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC6(CC5)NC(=O)CO6 |
−10.2
± 0.3
|
7.4
± 0.2
|
2461 |
EN300-1865348_3
|
|
CN(C)CCOCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.6
|
7.4
± 0.5
|
2462 |
EN300-363154_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc([nH]c5=O)CC6CC6 |
−10.2
± 0.3
|
7.4
± 0.2
|
2463 |
EN300-48760_3
|
|
CC(C)(C)NC(=O)CNC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2464 |
EN300-137784_4
|
|
CC1CCN(CC1)C(=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2465 |
EN300-31099_1
|
|
CCC(=O)NCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2466 |
EN300-312662_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]c(nn5)CO |
−10.2
± 0.3
|
7.4
± 0.2
|
2467 |
EN300-171215_1
|
|
CC1CS(=O)(=O)CCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.1
|
2468 |
EN300-6779469_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5C6C5CS(=O)(=O)C6 |
−10.2
± 0.2
|
7.4
± 0.1
|
2469 |
EN300-31210_1
|
|
CC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NS(=O)(=O)C |
−10.2
± 0.4
|
7.4
± 0.3
|
2470 |
EN300-160277_2
|
|
COCCn1ccc(n1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2471 |
EN300-174603_4
|
|
CN(C(=O)CCOCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−10.2
± 0.3
|
7.4
± 0.2
|
2472 |
EN300-1932013_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(CC(F)(F)F)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2473 |
EN300-30458_1
|
|
CN1CCC(CC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2474 |
EN300-107823_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCCn5ncnn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2475 |
EN300-85473_1
|
|
Cc1c(nnn1C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2476 |
EN300-249475_1
|
|
CC(=O)NC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.2
|
7.4
± 0.2
|
2477 |
EN300-1265948_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCS(=O)(=O)CC5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2478 |
EN300-682529_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5(CCOC5)CO |
−10.2
± 0.2
|
7.4
± 0.2
|
2479 |
EN300-50639_1
|
|
CC(C(=O)N(C)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)n5cccn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2480 |
EN300-26031_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5nnc6n5CCC6 |
−10.2
± 0.3
|
7.4
± 0.2
|
2481 |
EN300-33601_4
|
|
CN1CC(CC1=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2482 |
EN300-44993_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(cnc5)C(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|
2483 |
EN300-39033_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCNC(=O)c5ccncc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2484 |
EN300-248521_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C(C5)O)CO |
−10.2
± 0.2
|
7.4
± 0.2
|
2485 |
EN300-178515_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCC(=O)N |
−10.2
± 0.3
|
7.4
± 0.2
|
2486 |
EN300-52768_3
|
|
CCCS(=O)(=O)C(C)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.4
|
7.4
± 0.3
|
2487 |
EN300-114593_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5cccn6 |
−10.2
± 0.3
|
7.4
± 0.2
|
2488 |
EN300-21813_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5c(=O)c6ccccc6nn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2489 |
EN300-6473273_1
|
|
Cn1c(ccn1)C(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.2
± 0.1
|
7.41
± 0.09
|
2490 |
EN300-99161_1
|
|
CC1(CCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.2
± 0.2
|
7.4
± 0.2
|
2491 |
EN300-1265949_3
|
|
CC(C(=O)N1CCS(=O)(=O)CC1)OCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2492 |
EN300-204935_1
|
|
Cn1ncc(n1)C(=O)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2493 |
EN300-154693_3
|
|
CNC(=O)CCCCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.4
|
7.4
± 0.3
|
2494 |
EN300-195756_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5CCC(=O)N5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2495 |
EN300-67439_1
|
|
CCC1C(=O)NCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2496 |
EN300-103144_3
|
|
CSCCC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.3
|
7.4
± 0.2
|
2497 |
EN300-761618_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)Nc5cccnn5 |
−10.2
± 0.3
|
7.4
± 0.2
|
2498 |
EN300-109920_1
|
|
CC1COC(CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.2
± 0.3
|
7.4
± 0.2
|
2499 |
EN300-175608_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CCF)CO |
−10.2
± 0.3
|
7.4
± 0.2
|
2500 |
EN300-217526_1
|
|
CCn1c(c(nn1)C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.4
± 0.2
|