Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2301 |
EN300-6953121_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5C[C@H]5F |
−10.3
± 0.2
|
7.5
± 0.2
|
2302 |
EN300-7443878_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H](C5CCOCC5)O |
−10.3
± 0.3
|
7.5
± 0.2
|
2303 |
EN300-42154_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CS(=O)(=O)C5CCCC5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2304 |
EN300-7494115_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6c(=O)[nH]cnc6nc5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2305 |
EN300-14006_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCS(=O)(=O)C5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2306 |
EN300-123205_1
|
|
CNS(=O)(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.3
|
7.5
± 0.2
|
2307 |
EN300-120068_1
|
|
C[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)OC |
−10.3
± 0.2
|
7.5
± 0.2
|
2308 |
EN300-175474_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c(c(=O)[nH]cn6)C5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2309 |
EN300-7473032_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCNC(=O)C5C(=O)N |
−10.3
± 0.3
|
7.5
± 0.3
|
2310 |
EN300-7473354_1
|
|
Cc1ncn(n1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2311 |
EN300-05277_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCC(=O)N5CCOCC5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2312 |
EN300-244713_1
|
|
CO[C@H]1C[C@H](N(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.3
± 0.3
|
7.5
± 0.2
|
2313 |
EN300-10414_3
|
|
CC1(CCS(=O)(=O)C1)NC(=O)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2314 |
EN300-92664_3
|
|
COCCn1c(ccn1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2315 |
EN300-48902_1
|
|
CNC(=O)C1CCCN1C(=O)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2316 |
EN300-77343_2
|
|
Cc1nnnn1CCNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2317 |
EN300-77464_2
|
|
C[C@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.3
± 0.2
|
7.5
± 0.2
|
2318 |
EN300-7500408_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCCOC5)CO |
−10.3
± 0.2
|
7.5
± 0.1
|
2319 |
EN300-154944_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5OCCO5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2320 |
EN300-7121836_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn[nH]c5F |
−10.3
± 0.2
|
7.5
± 0.2
|
2321 |
EN300-115017_3
|
|
CC(C)[C@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.3
± 0.2
|
7.5
± 0.2
|
2322 |
EN300-207959_2
|
|
CC1(CCNC1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2323 |
EN300-6503811_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@H](Cc5cnc[nH]5)O |
−10.3
± 0.4
|
7.5
± 0.3
|
2324 |
EN300-191915_3
|
|
C[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)n5cnnn5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2325 |
EN300-378343_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC=CC5CO |
−10.3
± 0.2
|
7.5
± 0.2
|
2326 |
EN300-120586_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NCC(F)F |
−10.3
± 0.3
|
7.5
± 0.2
|
2327 |
EN300-31186_1
|
|
CCC(=O)NCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.3
|
7.5
± 0.2
|
2328 |
EN300-624143_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CC56CC(C6)O |
−10.3
± 0.2
|
7.5
± 0.2
|
2329 |
EN300-342226_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cnc[nH]5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2330 |
EN300-370753_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CC[C@H](C5)C(=O)N |
−10.3
± 0.3
|
7.5
± 0.2
|
2331 |
EN300-303908_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@]6(C[C@H]6C5)O |
−10.3
± 0.3
|
7.5
± 0.2
|
2332 |
EN300-30397_4
|
|
CC(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)n5cncn5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2333 |
EN300-299532_2
|
|
CC(C)(C(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−10.3
± 0.2
|
7.5
± 0.2
|
2334 |
EN300-31099_3
|
|
CCC(=O)NCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.3
|
7.5
± 0.2
|
2335 |
EN300-24014_3
|
|
CS(=O)(=O)N1CCCCC1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2336 |
EN300-31845_3
|
|
COCCN1CC(CC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2337 |
EN300-379219_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)CC6CNC(=O)O6 |
−10.3
± 0.3
|
7.5
± 0.2
|
2338 |
EN300-66461_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CNC(=O)N5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2339 |
DAR-DIA-0d514e7d-25
|
|
C[C@H]1COc2c(cc(cc2OC)Cl)[C@]1(C)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.1
|
7.47
± 0.10
|
2340 |
EN300-91905_2
|
|
C[C@@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.3
± 0.2
|
7.5
± 0.2
|
2341 |
EN300-05754_2
|
|
CC(C(=O)N1CCOCC1)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2342 |
EN300-120569_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)CCCC#N |
−10.3
± 0.2
|
7.5
± 0.2
|
2343 |
EN300-39501_4
|
|
COCCS(=O)(=O)CC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.5
|
7.5
± 0.4
|
2344 |
JAG-UCB-706446eb-4
|
|
CCOC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.2
|
7.5
± 0.2
|
2345 |
EN300-224741_3
|
|
CCC(CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.3
± 0.2
|
7.5
± 0.2
|
2346 |
EN300-55498_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)COc5ccc(cc5)C(=O)N |
−10.3
± 0.4
|
7.5
± 0.3
|
2347 |
EN300-97300_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CC5F |
−10.3
± 0.1
|
7.5
± 0.1
|
2348 |
EN300-6491795_1
|
|
CC1C2(CC(C2)(O1)CO)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.3
± 0.3
|
7.5
± 0.2
|
2349 |
EN300-18249_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N |
−10.3
± 0.2
|
7.5
± 0.1
|
2350 |
EN300-72109_1
|
|
CC(C)(C)OC(=O)NC(CO)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.3
|
7.5
± 0.2
|
2351 |
EN300-6745581_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nncn5C6CC6 |
−10.3
± 0.3
|
7.5
± 0.2
|
2352 |
EN300-1270299_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cn5)CO |
−10.3
± 0.3
|
7.5
± 0.2
|
2353 |
EN300-52380_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)CC(=O)N |
−10.3
± 0.3
|
7.5
± 0.2
|
2354 |
EN300-148515_1
|
|
Cn1c(nnn1)CN(C)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2355 |
EN300-386200_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC[C@H]([C@H](CC5)O)O |
−10.3
± 0.3
|
7.5
± 0.2
|
2356 |
EN300-1068239_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5cnon5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2357 |
EN300-73507_1
|
|
CC(=O)NCCNC(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.5
± 0.2
|
2358 |
EN300-6735698_2
|
|
CCNC(=O)C1(CC1)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2359 |
EN300-1719075_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(COC6)C(C5)(CO)F |
−10.2
± 0.3
|
7.5
± 0.2
|
2360 |
EN300-218116_4
|
|
CC(CO)(CO)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.5
|
7.5
± 0.3
|
2361 |
EN300-6497238_1
|
|
C[C@@H]1CS(=O)(=O)CCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.4
|
7.5
± 0.3
|
2362 |
EN300-1726073_3
|
|
Cn1c(cnn1)C(C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)(F)F |
−10.2
± 0.3
|
7.5
± 0.2
|
2363 |
EN300-218116_1
|
|
CC(CO)(CO)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.5
± 0.2
|
2364 |
EN300-154912_4
|
|
COc1nccc(n1)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.4
|
7.5
± 0.3
|
2365 |
EN300-98038_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]c(=O)[nH]n5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2366 |
EN300-221518_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCCO |
−10.2
± 0.1
|
7.46
± 0.08
|
2367 |
EN300-59285_1
|
|
CC(C)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.2
± 0.2
|
7.5
± 0.2
|
2368 |
EN300-70489_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC(C5)C#N |
−10.2
± 0.3
|
7.5
± 0.2
|
2369 |
EN300-6739235_1
|
|
CN([C@H]1C[C@@H](C1)C(=O)N[C@@]2(c3c(ccc(c3)Cl)OCC2)C(=O)Nc4c5c(cnc4)cccc5)C |
−10.2
± 0.3
|
7.5
± 0.3
|
2370 |
EN300-250593_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CC(=O)N5 |
−10.2
± 0.2
|
7.5
± 0.1
|
2371 |
EN300-68747_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCC5)C(=O)N |
−10.2
± 0.3
|
7.5
± 0.2
|
2372 |
EN300-152337_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(=O)NCC5 |
−10.2
± 0.2
|
7.5
± 0.1
|
2373 |
EN300-88656_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCCS5(=O)=O |
−10.2
± 0.3
|
7.5
± 0.2
|
2374 |
EN300-36690_3
|
|
Cn1c(=O)ccn(c1=O)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.4
|
7.5
± 0.3
|
2375 |
EN300-1662365_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCc6ncnn6C5 |
−10.2
± 0.2
|
7.5
± 0.2
|
2376 |
EN300-72896_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCC(=O)N5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2377 |
EN300-6488240_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5nncs5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2378 |
EN300-78753_1
|
|
CC1(COC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.5
± 0.2
|
2379 |
EN300-7463275_1
|
|
CC([C@@H]1C[C@H]1NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.2
± 0.2
|
7.5
± 0.1
|
2380 |
EN300-6743781_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCCNS(=O)(=O)CC5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2381 |
EN300-6491316_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc6cnnn6c5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2382 |
EN300-307008_3
|
|
CN1C(CNC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2383 |
EN300-6503811_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H](Cc5cnc[nH]5)O |
−10.2
± 0.2
|
7.5
± 0.2
|
2384 |
EN300-761209_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn(c5)CCO |
−10.2
± 0.3
|
7.5
± 0.2
|
2385 |
MAK-UNK-3875bbc8-1
|
|
Cc1ccc2c(c1)C(CCO2)C(=O)N(C)c3cncc4c3cccc4 |
−10.23
± 0.09
|
7.45
± 0.07
|
2386 |
EN300-31146_3
|
|
CN(CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)C5CC5 |
−10.2
± 0.4
|
7.5
± 0.3
|
2387 |
EN300-1212475_1
|
|
CC1(CC(=O)NCC1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.2
± 0.2
|
7.5
± 0.1
|
2388 |
EN300-24297_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5csnn5 |
−10.2
± 0.3
|
7.5
± 0.2
|
2389 |
EN300-66461_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CNC(=O)N5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2390 |
EN300-78727_1
|
|
Cc1nc(no1)CNC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2391 |
EN300-128464_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC(=O)NC5CC5 |
−10.2
± 0.4
|
7.4
± 0.3
|
2392 |
EN300-2010167_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc6n5nnc6 |
−10.2
± 0.4
|
7.4
± 0.3
|
2393 |
EN300-33657_3
|
|
CC(=O)N(C)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.3
|
2394 |
EN300-223964_3
|
|
CC[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N(C)C |
−10.2
± 0.3
|
7.4
± 0.2
|
2395 |
EN300-6478561_2
|
|
CN(CCNC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−10.2
± 0.3
|
7.4
± 0.2
|
2396 |
EN300-31242_4
|
|
COCC(=O)NCCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2397 |
EN300-55250_1
|
|
COCCOCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|
2398 |
EN300-195924_1
|
|
CC1(CCC(=O)NC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.2
± 0.2
|
7.4
± 0.2
|
2399 |
EN300-206592_2
|
|
CCCC(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−10.2
± 0.4
|
7.4
± 0.3
|
2400 |
EN300-154693_1
|
|
CNC(=O)CCCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.2
± 0.3
|
7.4
± 0.2
|