Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2101 |
EN300-31183_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)COC |
−10.4
± 0.3
|
7.6
± 0.3
|
2102 |
EN300-6743433_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccn6c(c5)cnn6 |
−10.4
± 0.2
|
7.6
± 0.2
|
2103 |
EN300-1387243_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@H]6[C@H]5COCC6 |
−10.4
± 0.4
|
7.6
± 0.3
|
2104 |
EN300-107435_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCCS5(=O)=O |
−10.4
± 0.2
|
7.6
± 0.2
|
2105 |
EN300-7456499_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCCS(=O)(=O)CCCO |
−10.4
± 0.4
|
7.6
± 0.3
|
2106 |
EN300-1273202_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCNC(=O)C(C5)(F)F |
−10.4
± 0.3
|
7.6
± 0.2
|
2107 |
EN300-1600786_1
|
|
Cn1cc(nn1)CCO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.2
|
7.6
± 0.1
|
2108 |
EN300-306047_3
|
|
Cn1cc(nn1)CCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2109 |
EN300-103187_1
|
|
CCOCCNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.4
± 0.3
|
7.6
± 0.2
|
2110 |
EN300-7442332_3
|
|
Cc1c(n(cn1)OC)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2111 |
EN300-158272_1
|
|
CC(=O)N1C[C@H](C[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC |
−10.4
± 0.4
|
7.6
± 0.3
|
2112 |
EN300-39458_1
|
|
Cc1c(c(n(n1)CCO)C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.4
|
7.6
± 0.3
|
2113 |
EN300-174603_2
|
|
CN(C(=O)CCOC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−10.4
± 0.3
|
7.6
± 0.2
|
2114 |
EN300-41828_1
|
|
CCOC(=O)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.4
± 0.2
|
7.6
± 0.2
|
2115 |
EN300-122340_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCSCC5)O |
−10.4
± 0.3
|
7.6
± 0.2
|
2116 |
EN300-1273019_1
|
|
CCc1[nH]c(=O)c(cn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2117 |
EN300-33398_3
|
|
CC(C)N1CC(CC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2118 |
EN300-86282_2
|
|
C[C@@H](CO)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.4
± 0.3
|
7.6
± 0.2
|
2119 |
EN300-185398_3
|
|
CC(C(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(F)F)O |
−10.4
± 0.3
|
7.6
± 0.2
|
2120 |
EN300-01527_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)NCC5CCCO5 |
−10.4
± 0.4
|
7.6
± 0.3
|
2121 |
EN300-208959_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CNC(=O)CC5C(F)(F)F |
−10.4
± 0.2
|
7.6
± 0.1
|
2122 |
EN300-104746_2
|
|
CCC(C)(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.4
± 0.3
|
7.6
± 0.2
|
2123 |
EN300-304662_2
|
|
Cc1nnc(o1)CCC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.2
|
7.6
± 0.2
|
2124 |
EN300-7465222_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5C[C@H]5N(=O)=O |
−10.4
± 0.3
|
7.6
± 0.2
|
2125 |
EN300-1448603_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CCS(=O)(=O)C5 |
−10.4
± 0.2
|
7.6
± 0.1
|
2126 |
EN300-366299_1
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CC(=O)NC[C@H]5C[C@@H](C5)O)cc1 |
−10.4
± 0.2
|
7.6
± 0.2
|
2127 |
EN300-101505_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(=O)N5 |
−10.4
± 0.2
|
7.6
± 0.1
|
2128 |
EN300-1723663_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCN(C(=O)C5)CCO |
−10.4
± 0.3
|
7.6
± 0.2
|
2129 |
EN300-7431365_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6n(c5)CCCNC6=O |
−10.4
± 0.3
|
7.6
± 0.2
|
2130 |
EN300-7439284_3
|
|
COc1cn[nH]c1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2131 |
ALP-POS-d3acb8cc-1
|
|
C[C@H]1C[C@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.37
± 0.09
|
7.56
± 0.06
|
2132 |
EN300-214552_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6c([nH]c(=O)[nH]6)nc5 |
−10.4
± 0.4
|
7.6
± 0.3
|
2133 |
EN300-18557_3
|
|
CC(=O)N1CCC(CC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.4
|
7.6
± 0.3
|
2134 |
EN300-28340_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCC(=O)N5CCCC5 |
−10.4
± 0.4
|
7.6
± 0.3
|
2135 |
EN300-7536177_3
|
|
Cc1ncnn1CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.4
|
7.6
± 0.3
|
2136 |
EN300-83558_3
|
|
Cc1ccnn1CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2137 |
EN300-153257_2
|
|
CC(C)C(CO)C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.4
± 0.3
|
7.6
± 0.2
|
2138 |
EN300-104395_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5CCCO5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2139 |
EN300-345656_1
|
|
C[C@@H]1C[C@@H](NC(=O)C1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.6
± 0.2
|
2140 |
EN300-217499_3
|
|
CC(C1CCOCC1)(C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.4
± 0.4
|
7.6
± 0.3
|
2141 |
EN300-817811_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)[nH]cn5 |
−10.4
± 0.2
|
7.6
± 0.1
|
2142 |
EN300-69313_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@H](C5)O |
−10.4
± 0.3
|
7.6
± 0.2
|
2143 |
EN300-102864_3
|
|
Cc1cc(cc(=O)n1CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.4
± 0.3
|
7.6
± 0.2
|
2144 |
EN300-7426781_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6cccn6ncn5 |
−10.4
± 0.2
|
7.6
± 0.2
|
2145 |
EN300-77092_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5OCCO5 |
−10.4
± 0.2
|
7.6
± 0.2
|
2146 |
EN300-11714_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5ccccc5=O |
−10.4
± 0.3
|
7.6
± 0.2
|
2147 |
EN300-140383_1
|
|
COC(=O)NC1CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.5
± 0.2
|
2148 |
EN300-59285_3
|
|
CC(C)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.4
± 0.3
|
7.5
± 0.2
|
2149 |
EN300-04073_4
|
|
CC(=O)NCCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.4
± 0.3
|
7.5
± 0.2
|
2150 |
MAK-UNK-8be7dca9-1
|
|
c1cc2c(cc1CN3CCNCC3)cncc2NC(=O)C4CCOc5c4cc(cc5)Cl |
−10.4
± 0.1
|
7.55
± 0.09
|
2151 |
EN300-6486793_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCCC5)S(=O)(=O)N |
−10.4
± 0.5
|
7.5
± 0.4
|
2152 |
EN300-119366_1
|
|
COCC1(CCN(CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.4
± 0.3
|
7.5
± 0.2
|
2153 |
EN300-66494_3
|
|
CNC(=O)NCCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.4
± 0.4
|
7.5
± 0.3
|
2154 |
EN300-260418_1
|
|
Cn1c(nc(n1)C2CC2)CC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.4
± 0.3
|
7.5
± 0.2
|
2155 |
EN300-316679_1
|
|
CCC[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.4
± 0.3
|
7.5
± 0.2
|
2156 |
EN300-31145_1
|
|
CC(C)C(=O)N(C)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.4
± 0.3
|
7.5
± 0.2
|
2157 |
EN300-1705754_4
|
|
CC1(CS(=O)(=O)C1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.5
± 0.2
|
2158 |
EN300-748753_1
|
|
C[C@]12CN(C[C@H]1CS(=O)(=O)C2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.4
± 0.4
|
7.5
± 0.3
|
2159 |
EN300-1699871_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CCS(=O)(=O)N5 |
−10.4
± 0.2
|
7.5
± 0.2
|
2160 |
EN300-120282_2
|
|
Cn1cc(nn1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.2
|
7.5
± 0.2
|
2161 |
VLA-UCB-50c39ae8-7
|
|
C=CC(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−10.4
± 0.2
|
7.5
± 0.1
|
2162 |
EN300-1703825_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@H]6[C@H]5CS(=O)(=O)C6 |
−10.4
± 0.4
|
7.5
± 0.3
|
2163 |
EN300-62574_4
|
|
Cn1c(nnn1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.5
± 0.2
|
2164 |
EN300-98038_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCc5[nH]c(=O)[nH]n5 |
−10.4
± 0.2
|
7.5
± 0.2
|
2165 |
EN300-246333_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H]6[C@H](C5)C(=O)NC6=O |
−10.4
± 0.4
|
7.5
± 0.3
|
2166 |
EN300-146491_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCCC(=O)N5 |
−10.4
± 0.3
|
7.5
± 0.2
|
2167 |
EN300-7444533_3
|
|
CC1CC(C(=O)O1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.4
± 0.3
|
7.5
± 0.2
|
2168 |
EN300-7471076_1
|
|
CC1C(CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.4
± 0.2
|
7.5
± 0.1
|
2169 |
EN300-97758_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCF |
−10.3
± 0.3
|
7.5
± 0.2
|
2170 |
EN300-106023_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(no5)C(=O)N |
−10.3
± 0.2
|
7.5
± 0.2
|
2171 |
EN300-86205_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5c(=O)[nH]cnc5O |
−10.3
± 0.4
|
7.5
± 0.3
|
2172 |
EN300-191771_1
|
|
CS(=O)(=O)C1(CCC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2173 |
EN300-00271_4
|
|
CC(C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−10.3
± 0.3
|
7.5
± 0.2
|
2174 |
EN300-173562_1
|
|
CC1CC(CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.3
± 0.2
|
7.5
± 0.1
|
2175 |
EN300-16091_3
|
|
CCS(=O)(=O)N1CCCC1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2176 |
EN300-67573_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NC5CCOCC5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2177 |
EN300-6487680_4
|
|
Cc1nnn(n1)CC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2178 |
EN300-2977549_2
|
|
CNC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.1
|
7.54
± 0.08
|
2179 |
EN300-6499639_1
|
|
Cc1cc(n(n1)C)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2180 |
EN300-1708882_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C[C@@H]5COC[C@H]5O |
−10.3
± 0.3
|
7.5
± 0.2
|
2181 |
EN300-302290_4
|
|
CS(=O)(=O)N1CC(C1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2182 |
EN300-101291_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(c(=O)[nH]c5=O)CCO |
−10.3
± 0.4
|
7.5
± 0.3
|
2183 |
EN300-6763991_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nnc6n5CCOC6 |
−10.3
± 0.3
|
7.5
± 0.2
|
2184 |
EN300-96175_1
|
|
CC(C)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N5CCOC5=O |
−10.3
± 0.6
|
7.5
± 0.4
|
2185 |
EN300-04492_1
|
|
COCCCNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.3
± 0.3
|
7.5
± 0.2
|
2186 |
EN300-359750_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CCC(=O)O5 |
−10.3
± 0.3
|
7.5
± 0.2
|
2187 |
EN300-1266218_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5c6c([nH]n5)nc[nH]c6=O |
−10.3
± 0.3
|
7.5
± 0.2
|
2188 |
EN300-141628_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc(c5)S(=O)(=O)N |
−10.3
± 0.5
|
7.5
± 0.3
|
2189 |
EN300-10334_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C56CCC(=O)N5CCS6 |
−10.3
± 0.3
|
7.5
± 0.2
|
2190 |
EN300-248618_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CS(=O)(=O)C5CC5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2191 |
EN300-13499_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCCNC(=O)N |
−10.3
± 0.2
|
7.5
± 0.2
|
2192 |
EN300-640503_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5C[C@H](C56CCOCC6)O |
−10.3
± 0.3
|
7.5
± 0.2
|
2193 |
EN300-7547467_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCN(C5=O)c6ccn[nH]6 |
−10.3
± 0.3
|
7.5
± 0.2
|
2194 |
EN300-1911992_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(C5CCOC5)O |
−10.3
± 0.2
|
7.5
± 0.2
|
2195 |
EN300-134855_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(c5cccnc5)O |
−10.3
± 0.3
|
7.5
± 0.2
|
2196 |
EN300-202922_2
|
|
CC(C(C)(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−10.3
± 0.2
|
7.5
± 0.1
|
2197 |
EN300-1706036_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5C(=O)NCCO5 |
−10.3
± 0.2
|
7.5
± 0.2
|
2198 |
EN300-1387104_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCS5(=O)=O |
−10.3
± 0.3
|
7.5
± 0.2
|
2199 |
EN300-48861_1
|
|
CNC(=O)Cn1cc(cn1)NC(=O)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.3
± 0.4
|
7.5
± 0.3
|
2200 |
EN300-270710_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCS(=O)(=O)N |
−10.3
± 0.3
|
7.5
± 0.2
|