Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1701 |
EN300-94900_2
|
|
CS(=O)(=O)Cc1nc(on1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.8
± 0.3
|
1702 |
EN300-246992_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCC(=O)NC5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1703 |
EN300-19242_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CO |
−10.6
± 0.2
|
7.7
± 0.1
|
1704 |
EN300-36089_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)c5ccncc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1705 |
EN300-1715993_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCn5ccnn5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1706 |
EN300-225786_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)Nc5nnnn5C6CC6 |
−10.6
± 0.3
|
7.7
± 0.2
|
1707 |
EN300-317555_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5=NCCO5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1708 |
EN300-305454_2
|
|
Cn1cc(cn1)[C@@H]2CCO[C@@H]2C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.6
± 0.4
|
7.7
± 0.3
|
1709 |
EN300-148421_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCOC5)O |
−10.6
± 0.3
|
7.7
± 0.2
|
1710 |
EN300-6498856_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCC5C(=O)NC(=O)N5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1711 |
EN300-247617_1
|
|
Cc1cc(ncc1C(=O)N)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1712 |
EN300-233678_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C(C5)CO)O |
−10.6
± 0.2
|
7.7
± 0.2
|
1713 |
EN300-2007648_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C56CC(C5)CO6 |
−10.6
± 0.3
|
7.7
± 0.2
|
1714 |
EN300-261365_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CS(=O)(=O)C5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1715 |
EN300-1608992_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)(C#N)C(=O)N |
−10.6
± 0.2
|
7.7
± 0.1
|
1716 |
EN300-20668_3
|
|
COC(=O)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1717 |
EN300-187060_2
|
|
Cn1nc(nn1)CNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1718 |
EN300-2011576_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5Cc6c(nccn6)C5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1719 |
EN300-223187_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5c6c(nn5)CCCC6 |
−10.6
± 0.3
|
7.7
± 0.2
|
1720 |
EN300-7440089_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6nccn6c(=O)[nH]5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1721 |
EN300-294731_1
|
|
Cn1c(c(cn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)N |
−10.6
± 0.3
|
7.7
± 0.2
|
1722 |
EN300-76841_1
|
|
CC(COC)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.6
± 0.3
|
7.7
± 0.2
|
1723 |
EN300-360157_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5(CCOC5)O |
−10.6
± 0.2
|
7.7
± 0.2
|
1724 |
EN300-104592_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCC5CCC(=O)N5 |
−10.6
± 0.3
|
7.7
± 0.3
|
1725 |
EN300-61636_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)C(=O)NC6CC6 |
−10.6
± 0.4
|
7.7
± 0.3
|
1726 |
EN300-121078_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CC5)CCO |
−10.6
± 0.3
|
7.7
± 0.2
|
1727 |
EN300-50631_1
|
|
CN(C)S(=O)(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.4
|
7.7
± 0.3
|
1728 |
EN300-6335413_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5C[C@H]5C(=O)NCCO |
−10.6
± 0.4
|
7.7
± 0.3
|
1729 |
EN300-154179_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6CC6(C5)CO |
−10.6
± 0.2
|
7.7
± 0.2
|
1730 |
EN300-07936_2
|
|
CCN(CC(=O)NC(C)C)C(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.4
|
7.7
± 0.3
|
1731 |
EN300-1703718_3
|
|
CC(=O)N1C[C@@H](C[C@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.6
± 0.4
|
7.7
± 0.3
|
1732 |
EN300-132523_3
|
|
CN(CCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−10.6
± 0.5
|
7.7
± 0.3
|
1733 |
EN300-153668_1
|
|
CC1CNC(=O)CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.7
± 0.3
|
1734 |
EN300-6238494_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)C5COCCO5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1735 |
EN300-250120_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCS(=O)(=O)CC5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1736 |
MAK-UNK-83e0a0b4-4
|
|
CCCCc1ccc2c(c1)C(CCO2)C(=O)N(CCNC3CNC3)c4cncc5c4cccc5 |
−10.6
± 0.5
|
7.7
± 0.3
|
1737 |
EN300-33601_3
|
|
CN1CC(CC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1738 |
EN300-141695_3
|
|
CN1CCC(C1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.7
± 0.3
|
1739 |
EN300-250593_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5CC(=O)N5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1740 |
EN300-92662_1
|
|
Cn1c(ccn1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1741 |
EN300-3143295_1
|
|
Cn1cnnc1[C@@H]2CC[C@@H]2C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.6
± 0.4
|
7.7
± 0.3
|
1742 |
EN300-6494859_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(OC5)Cn6cccn6 |
−10.6
± 0.3
|
7.7
± 0.2
|
1743 |
EN300-95639_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C(C5)O)CO |
−10.6
± 0.3
|
7.7
± 0.2
|
1744 |
EN300-344753_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(CC5)C(=O)NCCO |
−10.6
± 0.4
|
7.7
± 0.3
|
1745 |
EN300-02015_3
|
|
COCCNC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1746 |
EN300-73582_1
|
|
CCS(=O)(=O)NCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1747 |
EN300-194442_1
|
|
CC1(CCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C(=O)N |
−10.6
± 0.3
|
7.7
± 0.2
|
1748 |
EN300-1704404_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CNC(=O)CC56CCC6 |
−10.6
± 0.4
|
7.7
± 0.3
|
1749 |
EN300-74876_1
|
|
CC(=O)N1CC(C1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1750 |
EN300-785910_1
|
|
COCc1c(nn[nH]1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1751 |
EN300-373476_3
|
|
CC1(CCCS1(=O)=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1752 |
EN300-306047_4
|
|
Cn1cc(nn1)CCC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1753 |
EN300-06030_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cc5)n6cnnn6 |
−10.6
± 0.3
|
7.7
± 0.2
|
1754 |
EN300-718785_1
|
|
CCN1C(CCC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1755 |
EN300-202757_1
|
|
CC(CC(=O)N)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.2
|
7.7
± 0.2
|
1756 |
EN300-65050_1
|
|
CC(C)(CO)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1757 |
EN300-325729_1
|
|
COCC1COCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1758 |
EN300-142333_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C6(C5)CC6)O |
−10.6
± 0.2
|
7.7
± 0.2
|
1759 |
EN300-159634_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)[nH]nc5 |
−10.6
± 0.2
|
7.7
± 0.1
|
1760 |
EN300-135735_1
|
|
CN(CCn1cncn1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1761 |
EN300-3044054_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCC(=O)N5C6CC6 |
−10.6
± 0.2
|
7.7
± 0.2
|
1762 |
EN300-1695689_1
|
|
CC1(C(CS1(=O)=O)N(C)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.6
± 0.5
|
7.7
± 0.4
|
1763 |
EN300-21303_1
|
|
CCOCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.2
|
7.7
± 0.1
|
1764 |
EN300-25446_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cnco5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1765 |
EN300-120586_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCC(F)F |
−10.6
± 0.3
|
7.7
± 0.2
|
1766 |
EN300-1071940_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5(CCCOC5)O |
−10.6
± 0.2
|
7.7
± 0.2
|
1767 |
EN300-45049_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCS(=O)(=O)N5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1768 |
EN300-1719143_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]([C@@H](C5)O)CC#N |
−10.6
± 0.3
|
7.7
± 0.2
|
1769 |
EN300-172640_1
|
|
CC1C(NC(=O)O1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.1
|
1770 |
EN300-178829_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC(=O)NCC5CC5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1771 |
EN300-142130_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H](CO)C(F)(F)F |
−10.6
± 0.4
|
7.7
± 0.3
|
1772 |
EN300-97300_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC5F |
−10.6
± 0.1
|
7.72
± 0.08
|
1773 |
EN300-383904_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCNC(=O)CO |
−10.6
± 0.4
|
7.7
± 0.3
|
1774 |
EN300-214038_1
|
|
CC(CN(CCO)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.6
± 0.3
|
7.7
± 0.2
|
1775 |
EN300-300294_1
|
|
CS(=O)(=O)C[C@H]1CCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1776 |
EN300-23317_4
|
|
CC(C(=O)NCCOC)OCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1777 |
EN300-198240_3
|
|
Cn1cc(cn1)C(C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC |
−10.6
± 0.3
|
7.7
± 0.2
|
1778 |
EN300-173023_1
|
|
CC(=O)OC1(CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1779 |
EN300-54304_1
|
|
CCOCCOCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1780 |
EN300-178293_3
|
|
CN1CCN(CC1)C(=O)CCOCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.5
|
7.7
± 0.3
|
1781 |
EN300-76841_3
|
|
CC(COC)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.6
± 0.4
|
7.7
± 0.3
|
1782 |
EN300-61636_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CC5)C(=O)NC6CC6 |
−10.6
± 0.3
|
7.7
± 0.2
|
1783 |
EN300-685492_2
|
|
COCc1[nH]c(=O)c(cn1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.7
± 0.3
|
1784 |
EN300-124052_1
|
|
CC1CN(CC1O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.1
|
1785 |
EN300-248178_1
|
|
Cc1cn[nH]c1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.1
|
1786 |
EN300-6478526_1
|
|
CNC(=O)N1CCC(CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1787 |
EN300-19700_4
|
|
COC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.2
|
7.7
± 0.1
|
1788 |
EN300-1600363_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5C[C@H]5C#N |
−10.6
± 0.2
|
7.7
± 0.2
|
1789 |
EN300-1271924_1
|
|
Cc1cc(=O)c(cn1CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC |
−10.6
± 0.3
|
7.7
± 0.2
|
1790 |
EN300-252721_1
|
|
CS(=O)(=O)c1cccnc1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1791 |
EN300-6505003_3
|
|
CC1CCC(C(=O)N1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1792 |
EN300-27476_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5c(=O)n6ccccc6n5 |
−10.6
± 0.4
|
7.7
± 0.3
|
1793 |
EN300-10402_3
|
|
CS(=O)(=O)N1CCCC1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.7
± 0.3
|
1794 |
EN300-302058_1
|
|
CON1CCC(C1=O)O[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.7
± 0.2
|
1795 |
EN300-126104_3
|
|
Cc1cccn(c1=O)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1796 |
EN300-312450_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(n5)N6CCOCC6 |
−10.6
± 0.3
|
7.7
± 0.2
|
1797 |
EN300-23223_1
|
|
CNC(=O)CNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1798 |
EN300-307053_1
|
|
CC(=O)Nc1cc(c(=O)[nH]c1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.7
± 0.2
|
1799 |
EN300-68889_1
|
|
CCNC(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.7
± 0.2
|
1800 |
PET-UNK-29afea89-1
|
|
C#C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.1
|
7.71
± 0.08
|