Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1601 |
EN300-255496_1
|
|
CN1CCC(S1(=O)=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1602 |
EN300-64536_4
|
|
COCCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.7
± 0.3
|
7.8
± 0.2
|
1603 |
EN300-6740329_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C6CCCC5C(=O)NC6 |
−10.7
± 0.3
|
7.8
± 0.2
|
1604 |
EN300-268198_3
|
|
CC(CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−10.7
± 0.2
|
7.8
± 0.2
|
1605 |
EN300-220194_3
|
|
CC(C(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)OC |
−10.7
± 0.2
|
7.8
± 0.1
|
1606 |
EN300-7470991_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@H](C[C@H]5CO)CO |
−10.7
± 0.4
|
7.8
± 0.3
|
1607 |
EN300-22880_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCCC(C5)C(=O)N |
−10.7
± 0.3
|
7.8
± 0.2
|
1608 |
EN300-51257_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−10.7
± 0.2
|
7.8
± 0.2
|
1609 |
EN300-650518_1
|
|
CO[C@@H]1C[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.2
|
1610 |
EN300-2010167_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cccc6n5nnc6 |
−10.7
± 0.3
|
7.8
± 0.2
|
1611 |
EN300-144606_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn[nH]c5S(=O)(=O)N |
−10.7
± 0.3
|
7.8
± 0.2
|
1612 |
EN300-41425_1
|
|
Cc1cc(n[nH]1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1613 |
EN300-158082_1
|
|
CC1(CN(CC(O1)CO)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.7
± 0.5
|
7.8
± 0.3
|
1614 |
EN300-7102031_1
|
|
COCC(CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)COC |
−10.7
± 0.4
|
7.8
± 0.3
|
1615 |
EN300-158260_1
|
|
CC(=O)N1C[C@@H](C[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.7
± 0.3
|
7.8
± 0.2
|
1616 |
EN300-83691_2
|
|
Cc1c(nn[nH]1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.1
|
1617 |
EN300-6504697_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5CC6(CC6)S(=O)(=O)N5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1618 |
EN300-306047_1
|
|
Cn1cc(nn1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1619 |
EN300-66764_1
|
|
COC(=O)C1CC1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.1
|
1620 |
EN300-4698402_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5C[C@H]5F |
−10.7
± 0.2
|
7.8
± 0.1
|
1621 |
EN300-176877_1
|
|
CN(C)C(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.7
± 0.3
|
7.8
± 0.2
|
1622 |
EN300-185378_2
|
|
CC(COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.7
± 0.2
|
7.8
± 0.1
|
1623 |
EN300-127629_1
|
|
CC1(COCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.7
± 0.3
|
7.8
± 0.2
|
1624 |
EN300-637424_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)[C@@H]6COC[C@H]6O |
−10.7
± 0.3
|
7.8
± 0.2
|
1625 |
EN300-80083_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCCCC(=O)N5 |
−10.7
± 0.4
|
7.8
± 0.3
|
1626 |
EN300-4287199_1
|
|
Cc1cc(cc(=O)n1C)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1627 |
EN300-25960_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCCC5)O |
−10.7
± 0.3
|
7.8
± 0.2
|
1628 |
EN300-195590_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CCCNC(=O)C5 |
−10.7
± 0.2
|
7.8
± 0.1
|
1629 |
EN300-124301_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCCn5ccnn5 |
−10.7
± 0.4
|
7.8
± 0.3
|
1630 |
EN300-127197_4
|
|
COc1cc(on1)CC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1631 |
EN300-218116_3
|
|
CC(CO)(CO)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.7
± 0.4
|
7.8
± 0.3
|
1632 |
EN300-215799_1
|
|
Cc1c(c(no1)CO)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1633 |
EN300-96362_3
|
|
CC(C(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C5CC5)O |
−10.7
± 0.3
|
7.8
± 0.2
|
1634 |
EN300-77464_4
|
|
C[C@H](C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.7
± 0.3
|
7.8
± 0.3
|
1635 |
EN300-321790_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H]6C[C@H]5CO6 |
−10.7
± 0.3
|
7.8
± 0.2
|
1636 |
EN300-785910_2
|
|
COCc1c(nn[nH]1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.2
|
1637 |
EN300-109535_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CC(=O)OC5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1638 |
VLA-UCB-34f3ed0c-10
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCc5cc[nH]n5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1639 |
EN300-395654_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C6(C5)COC6)CO |
−10.7
± 0.3
|
7.8
± 0.2
|
1640 |
EN300-249804_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)C5CCOC(=O)N5 |
−10.7
± 0.4
|
7.8
± 0.3
|
1641 |
EN300-110423_3
|
|
Cc1c(c(=O)[nH]o1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1642 |
EN300-219020_1
|
|
Cn1ncc(n1)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.1
|
1643 |
EN300-201346_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5COC(=O)N5 |
−10.7
± 0.2
|
7.8
± 0.2
|
1644 |
EN300-74448_1
|
|
CCN(CCO)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.7
± 0.2
|
7.8
± 0.1
|
1645 |
EN300-82179_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC(=O)N |
−10.7
± 0.3
|
7.8
± 0.2
|
1646 |
EN300-12929_3
|
|
Cc1cc(no1)OCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1647 |
EN300-746187_1
|
|
Cc1nc2n(n1)CC(CC2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.7
± 0.3
|
7.8
± 0.2
|
1648 |
EN300-246992_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCC(=O)NC5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1649 |
EN300-155823_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CC#N)O |
−10.7
± 0.3
|
7.8
± 0.2
|
1650 |
EN300-2958082_3
|
|
C[C@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)NC |
−10.7
± 0.4
|
7.8
± 0.3
|
1651 |
EN300-16248_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cc5)S(=O)(=O)N |
−10.7
± 0.3
|
7.8
± 0.2
|
1652 |
EN300-116234_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCCO5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1653 |
EN300-2011083_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCC(=O)OCC5 |
−10.7
± 0.2
|
7.8
± 0.2
|
1654 |
EN300-1696043_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cn(nn5)C6COC6 |
−10.7
± 0.2
|
7.8
± 0.2
|
1655 |
EN300-18561_3
|
|
CC(=O)NCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.7
± 0.3
|
7.8
± 0.2
|
1656 |
EN300-51886_1
|
|
CN1CCC(CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.5
|
7.8
± 0.4
|
1657 |
EN300-7434334_1
|
|
Cn1cnc2c1ncnc2C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.7
± 0.3
|
7.8
± 0.2
|
1658 |
EN300-120569_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)CCCC#N |
−10.7
± 0.3
|
7.8
± 0.2
|
1659 |
EN300-101197_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCc5[nH]cnn5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1660 |
EN300-7493255_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(OCC56CC6)CO |
−10.7
± 0.3
|
7.8
± 0.2
|
1661 |
EN300-147397_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc6nccn6c5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1662 |
EN300-256075_1
|
|
CN(C)CCn1c(ccn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1663 |
EN300-155362_3
|
|
CC1CC(=O)NC1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.1
|
1664 |
EN300-158274_1
|
|
CC(=O)N1C[C@H](C[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.7
± 0.3
|
7.8
± 0.2
|
1665 |
EN300-11195_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCC5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1666 |
EN300-63872_1
|
|
Cn1cc(cn1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.2
|
1667 |
EN300-100583_1
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CC(=O)N[C@H]5C[C@H](C5)O)cc1 |
−10.7
± 0.3
|
7.8
± 0.2
|
1668 |
EN300-332838_1
|
|
CN1C(COC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.2
|
7.8
± 0.1
|
1669 |
EN300-310888_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5nnc6n5CCOCC6 |
−10.7
± 0.3
|
7.8
± 0.2
|
1670 |
EN300-704025_2
|
|
COC1(CS(=O)(=O)C1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1671 |
EN300-105110_4
|
|
Cc1cc(n[nH]1)CC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1672 |
EN300-106540_1
|
|
CC(CC(=O)OC)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.7
± 0.2
|
7.8
± 0.1
|
1673 |
DAR-DIA-6a508060-9
|
|
c1ccc2c(c1)cncc2NC(=O)C3(CCOc4c3cc(cc4)Cl)CCC5CCCCC5 |
−10.7
± 0.3
|
7.8
± 0.2
|
1674 |
EN300-259063_1
|
|
CC(=O)N1CCCC(C1)(CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.6
± 0.3
|
7.8
± 0.2
|
1675 |
EN300-23214_3
|
|
CCCNC(=O)C(C)NC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.8
± 0.2
|
1676 |
EN300-244947_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5c[nH]nn5 |
−10.6
± 0.4
|
7.8
± 0.3
|
1677 |
EN300-1241327_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCOCC5 |
−10.6
± 0.2
|
7.8
± 0.1
|
1678 |
EN300-866702_3
|
|
C=CCOC(=O)NCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.4
|
7.8
± 0.3
|
1679 |
EN300-103219_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CC(=O)N5 |
−10.6
± 0.2
|
7.8
± 0.2
|
1680 |
EN300-247343_1
|
|
CC1(CC(C1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.6
± 0.2
|
7.8
± 0.2
|
1681 |
EN300-259694_3
|
|
CCOC1(CCOC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.8
± 0.3
|
1682 |
EN300-1601684_3
|
|
CC1(C(OCCO1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.6
± 0.2
|
7.8
± 0.2
|
1683 |
EN300-65978_3
|
|
Cn1cc(cn1)CN(C)C(=O)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.5
|
7.8
± 0.4
|
1684 |
VLA-UCB-05e51b3f-12
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4OC5CC(=O)N5)Cl)CCC6CCCCC6 |
−10.6
± 0.3
|
7.8
± 0.2
|
1685 |
EN300-203293_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5CNC(=O)O5 |
−10.6
± 0.3
|
7.8
± 0.2
|
1686 |
EN300-393148_3
|
|
CN1C(CCS1(=O)=O)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.3
|
7.8
± 0.2
|
1687 |
EN300-7430501_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCn6c(cnn6)C5 |
−10.6
± 0.2
|
7.8
± 0.2
|
1688 |
EN300-73772_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5[nH]c(=O)[nH]n5 |
−10.6
± 0.3
|
7.8
± 0.3
|
1689 |
EN300-1911992_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(C5CCOC5)O |
−10.6
± 0.2
|
7.8
± 0.2
|
1690 |
EN300-100916_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5nccn5 |
−10.6
± 0.3
|
7.8
± 0.2
|
1691 |
EN300-7433125_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@]56C[C@@H]5[C@@H](C6)O |
−10.6
± 0.2
|
7.8
± 0.2
|
1692 |
EN300-206592_3
|
|
CCCC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−10.6
± 0.3
|
7.8
± 0.2
|
1693 |
EN300-225165_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CC(=O)NC(=O)C5 |
−10.6
± 0.3
|
7.8
± 0.2
|
1694 |
EN300-1932780_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(C(F)F)O |
−10.6
± 0.2
|
7.8
± 0.2
|
1695 |
EN300-102853_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccc6nnnn6c5 |
−10.6
± 0.3
|
7.8
± 0.2
|
1696 |
EN300-704025_3
|
|
COC1(CS(=O)(=O)C1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.8
± 0.3
|
1697 |
EN300-117414_1
|
|
CC(CO)N(C)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.6
± 0.3
|
7.8
± 0.2
|
1698 |
EN300-302290_2
|
|
CS(=O)(=O)N1CC(C1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.4
|
7.8
± 0.3
|
1699 |
EN300-379020_3
|
|
Cn1ccn2c(nnc2c1=O)COCC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.6
± 0.3
|
7.8
± 0.2
|
1700 |
EN300-263395_1
|
|
CN1CCN(CCC1=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.6
± 0.2
|
7.8
± 0.2
|