Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1401 |
EN300-365398_1
|
|
Cn1c(nnn1)CCO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1402 |
EN300-100180_1
|
|
CC(=O)N1CCC(C1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1403 |
EN300-98099_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(cs5)S(=O)(=O)N |
−10.8
± 0.3
|
7.9
± 0.2
|
1404 |
EN300-306316_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5[nH]cnn5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1405 |
EN300-201164_1
|
|
CC(C)(C)C(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−10.8
± 0.3
|
7.9
± 0.2
|
1406 |
EN300-120820_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cn[nH]c5=O |
−10.8
± 0.3
|
7.9
± 0.2
|
1407 |
EN300-125769_3
|
|
COCCCOCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.3
|
7.9
± 0.2
|
1408 |
EN300-23214_2
|
|
CCCNC(=O)C(C)NC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.3
|
7.9
± 0.2
|
1409 |
EN300-263153_3
|
|
Cn1cc(nn1)C(=O)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1410 |
EN300-122579_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCSCC5CO |
−10.8
± 0.3
|
7.9
± 0.2
|
1411 |
EN300-252683_1
|
|
CO[C@@H]1COC[C@@H]1NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1412 |
EN300-20496_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC5CCOC5=O |
−10.8
± 0.2
|
7.9
± 0.2
|
1413 |
EN300-31184_3
|
|
CC(C)C(=O)NC(C)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.3
|
7.9
± 0.2
|
1414 |
EN300-107267_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC5CCCNC5=O |
−10.8
± 0.2
|
7.9
± 0.1
|
1415 |
EN300-2958082_1
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)NC |
−10.8
± 0.3
|
7.9
± 0.2
|
1416 |
EN300-315792_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COCC(F)F |
−10.8
± 0.3
|
7.9
± 0.2
|
1417 |
EN300-7385389_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5cnc(n5)C(F)(F)F |
−10.8
± 0.3
|
7.9
± 0.2
|
1418 |
EN300-6486855_1
|
|
Cn1c(cnn1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.9
± 0.1
|
1419 |
EN300-205047_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6c(c[nH]5)S(=O)(=O)CC6 |
−10.8
± 0.3
|
7.9
± 0.2
|
1420 |
EN300-132613_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c(scn5)S(=O)(=O)N |
−10.8
± 0.2
|
7.9
± 0.2
|
1421 |
EN300-40153_1
|
|
CN(CC(=O)N)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.3
|
7.9
± 0.2
|
1422 |
EN300-20284_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC(C5)O |
−10.8
± 0.2
|
7.9
± 0.1
|
1423 |
EN300-1588617_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5C[C@@H]5C#N |
−10.8
± 0.2
|
7.9
± 0.2
|
1424 |
DAR-DIA-0d514e7d-28
|
|
C[C@H]1COc2ccc(cc2[C@]1(C)C(=O)Nc3cncc4c3cccc4)Cl |
−10.81
± 0.10
|
7.88
± 0.07
|
1425 |
EN300-191495_1
|
|
CS(=O)(=O)C1(CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1426 |
EN300-7540875_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnc6ncnn6c5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1427 |
EN300-370967_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCN5CCOC5=O |
−10.8
± 0.2
|
7.9
± 0.2
|
1428 |
EN300-01527_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCC5CCCO5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1429 |
EN300-1789253_2
|
|
Cn1cc(nn1)c2cc(no2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.8
± 0.2
|
7.9
± 0.2
|
1430 |
EN300-221518_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCCO |
−10.8
± 0.1
|
7.87
± 0.09
|
1431 |
EN300-7423123_1
|
|
Cc1nc(n(n1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.8
± 0.3
|
7.9
± 0.2
|
1432 |
DAR-DIA-5ff57136-9
|
|
COC(=O)/C=C/C(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−10.8
± 0.3
|
7.9
± 0.2
|
1433 |
EN300-342226_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5cnc[nH]5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1434 |
EN300-144970_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@H](C5)CO |
−10.8
± 0.2
|
7.9
± 0.2
|
1435 |
EN300-263392_2
|
|
CS(=O)(=O)Cc1nc(co1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1436 |
EN300-30687_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cccc(c5)OCC(=O)N |
−10.8
± 0.3
|
7.9
± 0.2
|
1437 |
EN300-51961_1
|
|
CCC(C)C(=O)NCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.2
|
7.9
± 0.2
|
1438 |
EN300-1988306_3
|
|
CS(=O)(=O)CCC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.4
|
7.9
± 0.3
|
1439 |
EN300-1718836_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5nnc6n5CCOC6 |
−10.8
± 0.3
|
7.9
± 0.2
|
1440 |
EN300-325738_3
|
|
CN1C(CCCC1=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1441 |
EN300-112757_2
|
|
Cn1cnnc1CCCNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1442 |
EN300-62448_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)C5CCC5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1443 |
EN300-16582_1
|
|
CC(C)C(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−10.8
± 0.3
|
7.9
± 0.2
|
1444 |
EN300-6497975_1
|
|
Cc1c(cnc(n1)CO)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.4
|
7.9
± 0.3
|
1445 |
EN300-259849_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCCCC(C5=O)O |
−10.8
± 0.3
|
7.9
± 0.2
|
1446 |
EN300-22879_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)N5CCCCC5C(=O)N |
−10.8
± 0.4
|
7.9
± 0.3
|
1447 |
EN300-255791_2
|
|
CN(C)CCn1ccc(n1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1448 |
EN300-125140_1
|
|
COCC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.2
|
7.9
± 0.2
|
1449 |
EN300-90293_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCc6c([nH]nn6)C5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1450 |
EN300-179091_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COC(F)F |
−10.8
± 0.2
|
7.9
± 0.2
|
1451 |
EN300-251396_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC(C5)(CO)O |
−10.8
± 0.4
|
7.9
± 0.3
|
1452 |
EN300-21009_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCO5 |
−10.8
± 0.2
|
7.9
± 0.1
|
1453 |
EN300-1719401_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@H](CO)c5[nH]cnn5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1454 |
EN300-222357_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCc5c[nH]nn5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1455 |
EN300-121144_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cc5ccccc5C(=O)N |
−10.8
± 0.3
|
7.9
± 0.2
|
1456 |
EN300-7457159_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5cc(on5)C6(COC6)O |
−10.8
± 0.4
|
7.9
± 0.3
|
1457 |
EN300-10170_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(CO)NC(=O)N |
−10.8
± 0.2
|
7.9
± 0.2
|
1458 |
EN300-79022_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5cccnn5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1459 |
EN300-99983_4
|
|
CNC(=O)Cc1nc(on1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.4
|
7.9
± 0.3
|
1460 |
EN300-1267093_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@H]6C[C@@]6(C5)O |
−10.8
± 0.3
|
7.9
± 0.2
|
1461 |
EN300-321110_2
|
|
C[C@@H]1[C@@H](CCS1(=O)=O)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1462 |
EN300-304771_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5CCN(C5=O)C6CC6 |
−10.8
± 0.3
|
7.9
± 0.2
|
1463 |
EN300-118760_3
|
|
CC(C1CC1)(C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.8
± 0.4
|
7.9
± 0.3
|
1464 |
EN300-1592151_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc6ncnn6c5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1465 |
EN300-96362_1
|
|
CC(C(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C5CC5)O |
−10.8
± 0.2
|
7.9
± 0.1
|
1466 |
EN300-217494_1
|
|
CC(C1CCOC1)(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.8
± 0.2
|
7.9
± 0.2
|
1467 |
EN300-258702_3
|
|
Cn1ccc(n1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1468 |
EN300-146051_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(nc5)CO |
−10.8
± 0.3
|
7.9
± 0.2
|
1469 |
EN300-7429970_1
|
|
CS(=O)(=O)CC1CC(C1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.4
|
7.9
± 0.3
|
1470 |
EN300-125140_4
|
|
COCC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.3
|
7.9
± 0.3
|
1471 |
EN300-313410_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(ncn5)N6CCOCC6 |
−10.8
± 0.3
|
7.8
± 0.2
|
1472 |
EN300-7459768_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CC(C5)(C6(CCC6)O)O |
−10.8
± 0.4
|
7.8
± 0.3
|
1473 |
EN300-395954_1
|
|
CC12CN(CCN1C(=O)OC2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.8
± 0.4
|
7.8
± 0.3
|
1474 |
EN300-126412_1
|
|
CN(Cc1ncon1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.8
± 0.2
|
1475 |
EN300-182913_1
|
|
CC(C)(C(=O)N)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.3
|
7.8
± 0.2
|
1476 |
EN300-317082_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC5COC5 |
−10.8
± 0.2
|
7.8
± 0.1
|
1477 |
EN300-55109_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC5CO |
−10.8
± 0.2
|
7.8
± 0.2
|
1478 |
EN300-92031_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCc5nc(no5)c6[nH]cnn6 |
−10.8
± 0.3
|
7.8
± 0.2
|
1479 |
EN300-1072874_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCNC(=O)CC5 |
−10.8
± 0.4
|
7.8
± 0.3
|
1480 |
EN300-31183_1
|
|
CC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)COC |
−10.8
± 0.3
|
7.8
± 0.2
|
1481 |
EN300-86357_1
|
|
Cn1cc(nn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.8
± 0.1
|
1482 |
EN300-262409_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cn5)n6cnnn6 |
−10.8
± 0.2
|
7.8
± 0.2
|
1483 |
EN300-170463_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCOC5 |
−10.8
± 0.3
|
7.8
± 0.2
|
1484 |
EN300-252961_1
|
|
COCC1CC(CN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.8
± 0.3
|
7.8
± 0.2
|
1485 |
EN300-08065_1
|
|
c1ccc(cc1)c2nnn(n2)CC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.8
± 0.3
|
7.8
± 0.2
|
1486 |
EN300-6742996_1
|
|
COC[C@@H]1CN(CCO1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.8
± 0.2
|
1487 |
EN300-122656_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCSC5)O |
−10.8
± 0.4
|
7.8
± 0.3
|
1488 |
EN300-88417_1
|
|
Cn1cncc1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.8
± 0.2
|
1489 |
EN300-315963_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)Cc5cnoc5 |
−10.8
± 0.3
|
7.8
± 0.2
|
1490 |
EN300-256583_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CS(=O)(=O)C5 |
−10.8
± 0.2
|
7.8
± 0.2
|
1491 |
EN300-42536_1
|
|
Cc1cc([nH]c(=O)n1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.8
± 0.2
|
1492 |
EN300-6736413_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC5CCNC5=O |
−10.8
± 0.2
|
7.8
± 0.1
|
1493 |
EN300-85760_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCO5 |
−10.8
± 0.2
|
7.8
± 0.1
|
1494 |
EN300-44149_3
|
|
Cn1c2c(cn1)c(=O)[nH]c(n2)COCC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.8
± 0.3
|
7.8
± 0.2
|
1495 |
EN300-366687_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCc6nncn6CC5 |
−10.8
± 0.2
|
7.8
± 0.2
|
1496 |
EN300-7003350_1
|
|
CCNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.1
|
7.84
± 0.08
|
1497 |
EN300-22884_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)N5CCNC(=O)C5 |
−10.8
± 0.3
|
7.8
± 0.2
|
1498 |
EN300-6729747_3
|
|
Cc1nnc2n1CC(C2)C(=O)NCC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.8
± 0.3
|
7.8
± 0.2
|
1499 |
EN300-107990_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)c5cccnc5 |
−10.8
± 0.3
|
7.8
± 0.2
|
1500 |
EN300-64297_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cncnc5 |
−10.8
± 0.2
|
7.8
± 0.1
|