Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1301 |
EN300-191904_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCn5cnnn5 |
−10.9
± 0.3
|
7.9
± 0.3
|
1302 |
EN300-1932013_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C(CC(F)(F)F)O |
−10.9
± 0.3
|
7.9
± 0.2
|
1303 |
EN300-257405_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC(C5)(CC#N)O |
−10.9
± 0.2
|
7.9
± 0.2
|
1304 |
EN300-248526_1
|
|
c1ccc(cc1)C(CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)(C(=O)N)O |
−10.9
± 0.4
|
7.9
± 0.3
|
1305 |
EN300-132157_3
|
|
CC1(CC(=O)NC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1306 |
EN300-99391_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)COC5CCOC5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1307 |
EN300-19700_1
|
|
COC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.1
|
7.94
± 0.09
|
1308 |
EN300-1273016_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCCc6n5ncn6 |
−10.9
± 0.2
|
7.9
± 0.1
|
1309 |
EN300-85760_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCO5 |
−10.9
± 0.1
|
7.9
± 0.1
|
1310 |
EN300-2007564_1
|
|
CC1(C(CCS1(=O)=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−10.9
± 0.3
|
7.9
± 0.2
|
1311 |
EN300-36845_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)C5CCCC5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1312 |
EN300-6478526_3
|
|
CNC(=O)N1CCC(CC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1313 |
EN300-103144_1
|
|
CSCCC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.9
± 0.2
|
7.9
± 0.2
|
1314 |
EN300-125409_1
|
|
CC(C(=O)N)N(C)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.3
|
7.9
± 0.2
|
1315 |
DAR-DIA-0d514e7d-6
|
|
C[C@H]1COc2c(cc(cc2OC3CC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.1
|
1316 |
EN300-193679_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCC5(CCCOC5)O |
−10.9
± 0.2
|
7.9
± 0.1
|
1317 |
EN300-33601_1
|
|
CN1CC(CC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1318 |
EN300-370280_3
|
|
C[C@]1(CCC(=O)N1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1319 |
EN300-04614_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(=O)[nH]n5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1320 |
EN300-14006_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCS(=O)(=O)C5 |
−10.9
± 0.4
|
7.9
± 0.3
|
1321 |
EN300-145616_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CCc5cnc[nH]5 |
−10.9
± 0.4
|
7.9
± 0.3
|
1322 |
EN300-25702_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CC5)O |
−10.9
± 0.2
|
7.9
± 0.2
|
1323 |
EN300-863933_3
|
|
CC(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N(C)C(=O)C |
−10.9
± 0.3
|
7.9
± 0.2
|
1324 |
EN300-31553_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCS(=O)(=O)N |
−10.9
± 0.2
|
7.9
± 0.2
|
1325 |
EN300-265285_1
|
|
CC1Cn2c(cc(n2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)C(=O)N1 |
−10.9
± 0.2
|
7.9
± 0.2
|
1326 |
EN300-102347_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5(COC5)CO |
−10.9
± 0.2
|
7.9
± 0.2
|
1327 |
EN300-69162_1
|
|
CC(COC)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
7.9
± 0.2
|
1328 |
EN300-1707774_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)OC(=O)N |
−10.9
± 0.2
|
7.9
± 0.2
|
1329 |
EN300-18564_1
|
|
CC(=O)NCCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.3
|
7.9
± 0.2
|
1330 |
EN300-74089_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCOCC5)C#N |
−10.9
± 0.3
|
7.9
± 0.2
|
1331 |
EN300-154201_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOCC5CO |
−10.9
± 0.2
|
7.9
± 0.1
|
1332 |
EN300-113507_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C(=O)N |
−10.9
± 0.2
|
7.9
± 0.2
|
1333 |
DAR-DIA-5ff57136-15
|
|
C#CC1(CC1)N(c2cncc3c2cccc3)C(=O)[C@@H]4CCOc5c4cc(cc5)Cl |
−10.9
± 0.2
|
7.9
± 0.1
|
1334 |
EN300-6738732_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@]56COC[C@H]5C6(F)F |
−10.9
± 0.3
|
7.9
± 0.2
|
1335 |
EN300-19515_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CCC(=O)N5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1336 |
EN300-189563_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCC5CS(=O)(=O)C5 |
−10.9
± 0.4
|
7.9
± 0.3
|
1337 |
EN300-297451_1
|
|
CC(C)[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−10.9
± 0.2
|
7.9
± 0.2
|
1338 |
EN300-248888_2
|
|
CC(C=C)(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.9
± 0.3
|
7.9
± 0.2
|
1339 |
EN300-113234_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC(=O)OC5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1340 |
EN300-181558_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CC5(CCC(CC5)O)O |
−10.9
± 0.2
|
7.9
± 0.2
|
1341 |
EN300-144606_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5cn[nH]c5S(=O)(=O)N |
−10.9
± 0.3
|
7.9
± 0.2
|
1342 |
EN300-1081277_1
|
|
CNC(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
7.9
± 0.2
|
1343 |
EN300-195590_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCCNC(=O)C5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1344 |
EN300-12247_1
|
|
CC(C)(C)C(=O)NCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.3
|
7.9
± 0.2
|
1345 |
EN300-25865_1
|
|
Cn1c2c(cn1)c(=O)n(cn2)CC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.9
± 0.4
|
7.9
± 0.3
|
1346 |
EN300-174668_2
|
|
COC1(CCOC1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1347 |
EN300-139167_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC5COCCO5 |
−10.9
± 0.1
|
7.92
± 0.09
|
1348 |
EN300-237561_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5c(=O)cccn5 |
−10.9
± 0.4
|
7.9
± 0.3
|
1349 |
EN300-315453_1
|
|
Cc1cncn1CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1350 |
EN300-244122_1
|
|
CC1(CN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.9
± 0.3
|
7.9
± 0.2
|
1351 |
EN300-298552_3
|
|
COC(C1CCOC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.1
|
1352 |
EN300-6238494_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)C5COCCO5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1353 |
EN300-706065_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(C5(CCOCC5)O)(F)F |
−10.9
± 0.3
|
7.9
± 0.2
|
1354 |
EN300-2910941_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cc(nn5)C(F)(F)F |
−10.9
± 0.3
|
7.9
± 0.2
|
1355 |
EN300-249804_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CCOC(=O)N5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1356 |
EN300-151423_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5(CCOCC5)O |
−10.9
± 0.3
|
7.9
± 0.2
|
1357 |
EN300-304378_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H](C[C@H](C5)F)O |
−10.9
± 0.3
|
7.9
± 0.2
|
1358 |
EN300-201553_3
|
|
Cn1cc(cn1)OCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1359 |
EN300-06654_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cn5cncn5 |
−10.9
± 0.2
|
7.9
± 0.1
|
1360 |
EN300-266736_2
|
|
Cc1c(nc[nH]1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.1
|
1361 |
EN300-58880_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(cn5)C(=O)N |
−10.9
± 0.2
|
7.9
± 0.2
|
1362 |
EN300-331828_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCO[C@@H]5COC[C@H]5O |
−10.9
± 0.3
|
7.9
± 0.2
|
1363 |
EN300-132624_3
|
|
CCC(=O)CNC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.4
|
7.9
± 0.3
|
1364 |
EN300-158260_3
|
|
CC(=O)N1C[C@@H](C[C@@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.9
± 0.4
|
7.9
± 0.3
|
1365 |
EN300-64247_3
|
|
CC(C)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N5CCOCC5 |
−10.9
± 0.4
|
7.9
± 0.3
|
1366 |
EN300-109540_1
|
|
CC(c1cn(nn1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−10.9
± 0.3
|
7.9
± 0.2
|
1367 |
EN300-232035_1
|
|
Cc1cnc2nc(nn2c1)CCC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−10.9
± 0.3
|
7.9
± 0.2
|
1368 |
EN300-1072972_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCOC5=O |
−10.9
± 0.4
|
7.9
± 0.3
|
1369 |
EN300-1248250_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CN(C5)C(=O)N |
−10.9
± 0.2
|
7.9
± 0.2
|
1370 |
EN300-264301_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOC[C@@H]5CCC(=O)N5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1371 |
EN300-2983332_2
|
|
CC(C)C1CNC(=O)CN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1372 |
EN300-142432_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)NC(=O)C6CC6 |
−10.8
± 0.3
|
7.9
± 0.2
|
1373 |
EN300-109535_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5CC(=O)OC5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1374 |
EN300-317555_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5=NCCO5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1375 |
EN300-7457160_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5=NOC(C5)CC6(COC6)O |
−10.8
± 0.3
|
7.9
± 0.2
|
1376 |
EN300-77464_1
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−10.8
± 0.2
|
7.9
± 0.1
|
1377 |
EN300-114805_1
|
|
Cn1c(ccn1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.2
|
7.9
± 0.1
|
1378 |
EN300-51411_1
|
|
Cn1cc(cn1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1379 |
EN300-11300_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5cc(=O)[nH]c(=O)[nH]5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1380 |
EN300-220536_1
|
|
CS(=O)(=O)C1(CCOCC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1381 |
EN300-6746918_1
|
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)NC(=O)[C@H]5C[C@](C5)(F)CO)cc1 |
−10.8
± 0.3
|
7.9
± 0.2
|
1382 |
EN300-47500_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCCCn5cccn5 |
−10.8
± 0.4
|
7.9
± 0.3
|
1383 |
EN300-265285_2
|
|
CC1Cn2c(cc(n2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)C(=O)N1 |
−10.8
± 0.3
|
7.9
± 0.2
|
1384 |
EN300-1664603_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCc5ccn[nH]5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1385 |
EN300-249093_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOCC5CC(=O)N |
−10.8
± 0.3
|
7.9
± 0.2
|
1386 |
EN300-364679_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCn5cnnn5 |
−10.8
± 0.2
|
7.9
± 0.2
|
1387 |
EN300-1608590_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCc5nc(on5)N6CCOCC6 |
−10.8
± 0.4
|
7.9
± 0.3
|
1388 |
EN300-36522_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)C5CC5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1389 |
EN300-393341_1
|
|
COc1cc(nc(n1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC |
−10.8
± 0.3
|
7.9
± 0.2
|
1390 |
EN300-64536_1
|
|
COCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.2
|
7.9
± 0.2
|
1391 |
EN300-256174_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N(CCO)c5ccncn5 |
−10.8
± 0.4
|
7.9
± 0.3
|
1392 |
EN300-123205_3
|
|
CNS(=O)(=O)CCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.3
|
7.9
± 0.2
|
1393 |
EN300-36495_2
|
|
CCOC(=O)NCCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.8
± 0.2
|
7.9
± 0.1
|
1394 |
EN300-650518_3
|
|
CO[C@@H]1C[C@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1395 |
EN300-62448_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)C5CCC5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1396 |
EN300-1709410_1
|
|
CC1CC(N1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.8
± 0.2
|
7.9
± 0.1
|
1397 |
EN300-1272865_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@]6(CC[C@]6(C5)CO)CO |
−10.8
± 0.3
|
7.9
± 0.2
|
1398 |
EN300-180875_1
|
|
CN(C)C(=O)C1(CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.3
|
7.9
± 0.2
|
1399 |
EN300-11441_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cc(=O)[nH]c(=O)[nH]5 |
−10.8
± 0.3
|
7.9
± 0.3
|
1400 |
EN300-223491_3
|
|
Cn1cnn(c1=O)CCC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.8
± 0.4
|
7.9
± 0.3
|