Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
1201 |
EN300-269525_1
|
|
Cc1nn(c(=O)n1C)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.3
|
8.0
± 0.3
|
1202 |
EN300-373791_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)c5ccnn5CC#N |
−11.0
± 0.2
|
8.0
± 0.2
|
1203 |
EN300-7493922_3
|
|
Cn1cnc(n1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.4
|
8.0
± 0.3
|
1204 |
EN300-103722_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5OCCC6 |
−11.0
± 0.2
|
8.0
± 0.2
|
1205 |
EN300-1704404_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CNC(=O)CC56CCC6 |
−11.0
± 0.3
|
8.0
± 0.2
|
1206 |
EN300-60831_1
|
|
CS(=O)(=O)C1(CCCC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.5
|
8.0
± 0.3
|
1207 |
EN300-6974806_3
|
|
C[C@H]([C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−11.0
± 0.4
|
8.0
± 0.3
|
1208 |
EN300-6494158_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5CC(CO5)CO |
−11.0
± 0.2
|
8.0
± 0.2
|
1209 |
EN300-74167_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)C5CCOCC5 |
−11.0
± 0.4
|
8.0
± 0.3
|
1210 |
EN300-755161_3
|
|
Cn1ncc(n1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.3
|
8.0
± 0.2
|
1211 |
EN300-245205_1
|
|
COc1nc(co1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.2
|
8.0
± 0.1
|
1212 |
EN300-6356960_1
|
|
Cn1cnnc1CCCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.3
|
8.0
± 0.2
|
1213 |
EN300-204239_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(=O)[nH]c(n5)C6CC6 |
−11.0
± 0.3
|
8.0
± 0.2
|
1214 |
EN300-66770_1
|
|
CNC(=O)C1(CC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.3
|
8.0
± 0.2
|
1215 |
EN300-206592_1
|
|
CCCC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−11.0
± 0.2
|
8.0
± 0.2
|
1216 |
EN300-6498076_3
|
|
Cc1c(c(=O)ccn1CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−11.0
± 0.3
|
8.0
± 0.2
|
1217 |
EN300-55072_3
|
|
CC(CO)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.0
± 0.2
|
8.0
± 0.1
|
1218 |
EN300-46832_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NCC5CCOC5 |
−11.0
± 0.3
|
8.0
± 0.2
|
1219 |
EN300-343474_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCNC5=O |
−11.0
± 0.3
|
8.0
± 0.2
|
1220 |
VLA-UCB-50c39ae8-1
|
|
CC(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−11.0
± 0.2
|
8.0
± 0.1
|
1221 |
EN300-13343_1
|
|
Cc1c(c(n2c(n1)ncn2)C)CC(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−11.0
± 0.4
|
8.0
± 0.3
|
1222 |
EN300-59478_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCCC(=O)N |
−11.0
± 0.3
|
8.0
± 0.2
|
1223 |
EN300-244403_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CNC(=O)O5 |
−11.0
± 0.2
|
8.0
± 0.2
|
1224 |
EN300-658559_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CC5)n6ccnn6 |
−11.0
± 0.3
|
8.0
± 0.2
|
1225 |
EN300-131572_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5cncc6 |
−11.0
± 0.3
|
8.0
± 0.2
|
1226 |
EN300-18074_4
|
|
CC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−11.0
± 0.2
|
8.0
± 0.2
|
1227 |
EN300-220536_3
|
|
CS(=O)(=O)C1(CCOCC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.4
|
8.0
± 0.3
|
1228 |
EN300-102901_3
|
|
CCC[C@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−11.0
± 0.3
|
8.0
± 0.2
|
1229 |
EN300-207873_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5(CC5)O |
−11.0
± 0.3
|
8.0
± 0.2
|
1230 |
EN300-6792206_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H](C5CCOCC5)O |
−11.0
± 0.3
|
8.0
± 0.2
|
1231 |
EN300-214800_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCN5CCNC5=O |
−11.0
± 0.3
|
8.0
± 0.2
|
1232 |
EN300-7444950_1
|
|
COc1cc(ncn1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.3
|
8.0
± 0.2
|
1233 |
EN300-101443_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(COC5)O |
−11.0
± 0.3
|
8.0
± 0.2
|
1234 |
EN300-30768_1
|
|
CC1CC1C(=O)NCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−11.0
± 0.2
|
8.0
± 0.1
|
1235 |
EN300-6743433_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccn6c(c5)cnn6 |
−10.9
± 0.3
|
8.0
± 0.2
|
1236 |
EN300-2010317_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6C[C@@H]5[C@@H](C6)O |
−10.9
± 0.3
|
8.0
± 0.2
|
1237 |
EN300-214800_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCN5CCNC5=O |
−10.9
± 0.3
|
8.0
± 0.2
|
1238 |
EN300-195924_3
|
|
CC1(CCC(=O)NC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
8.0
± 0.2
|
1239 |
EN300-263669_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@]56C[C@H]5COC6 |
−10.9
± 0.2
|
8.0
± 0.2
|
1240 |
EN300-270710_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCS(=O)(=O)N |
−10.9
± 0.3
|
8.0
± 0.2
|
1241 |
EN300-120586_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCC(F)F |
−10.9
± 0.3
|
8.0
± 0.2
|
1242 |
EN300-1688974_2
|
|
CC(CC(=O)N)N(C)C(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
8.0
± 0.1
|
1243 |
EN300-33478_1
|
|
CCN1CC(CC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1244 |
EN300-75875_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnnc5 |
−10.9
± 0.2
|
8.0
± 0.1
|
1245 |
EN300-53677_1
|
|
CS(=O)(=O)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
8.0
± 0.2
|
1246 |
EN300-6736413_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC5CCNC5=O |
−10.9
± 0.1
|
7.97
± 0.09
|
1247 |
EN300-127156_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc(no5)C(=O)N |
−10.9
± 0.3
|
8.0
± 0.2
|
1248 |
EN300-212814_1
|
|
CC1CN(CC(O1)CCO)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
8.0
± 0.2
|
1249 |
EN300-316193_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6COC(=O)[C@H]6C5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1250 |
EN300-69727_1
|
|
CC(C)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)OC |
−10.9
± 0.3
|
8.0
± 0.2
|
1251 |
EN300-249764_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(C5CCC5)O |
−10.9
± 0.2
|
8.0
± 0.2
|
1252 |
EN300-120436_1
|
|
Cn1cnn(c1=O)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.3
|
1253 |
EN300-188356_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCOC5)F |
−10.9
± 0.3
|
8.0
± 0.2
|
1254 |
EN300-137784_1
|
|
CC1CCN(CC1)C(=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1255 |
EN300-378044_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5CC=CCO5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1256 |
EN300-299806_1
|
|
COC1(CCCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−10.9
± 0.4
|
8.0
± 0.3
|
1257 |
EN300-220676_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CCCS(=O)(=O)C5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1258 |
EN300-174603_3
|
|
CN(C(=O)CCOCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−10.9
± 0.3
|
8.0
± 0.2
|
1259 |
EN300-88819_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5c6c(on5)CCOC6 |
−10.9
± 0.2
|
8.0
± 0.2
|
1260 |
EN300-62074_1
|
|
CC(=O)NC(CCOC)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
8.0
± 0.2
|
1261 |
EN300-193399_3
|
|
CC(C)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C5CC5 |
−10.9
± 0.3
|
8.0
± 0.3
|
1262 |
EN300-158292_1
|
|
CC(=O)NC(C1CCOCC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1263 |
EN300-1425677_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCCO5)CO |
−10.9
± 0.2
|
8.0
± 0.2
|
1264 |
EN300-6738732_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@]56COC[C@H]5C6(F)F |
−10.9
± 0.3
|
8.0
± 0.2
|
1265 |
EN300-202757_3
|
|
CC(CC(=O)N)C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.3
|
8.0
± 0.2
|
1266 |
EN300-203940_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5[nH]ccc6=O |
−10.9
± 0.2
|
8.0
± 0.2
|
1267 |
EN300-52325_3
|
|
CCCS(=O)(=O)CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.5
|
8.0
± 0.3
|
1268 |
EN300-92472_1
|
|
Cn1c(ccn1)COCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1269 |
EN300-7355519_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CC5CC6C(O5)CCO6 |
−10.9
± 0.2
|
8.0
± 0.1
|
1270 |
EN300-6759637_1
|
|
C[C@@H]1CN(C[C@H](O1)CO)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1271 |
EN300-1605566_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CN6CCN5CC6 |
−10.9
± 0.3
|
8.0
± 0.2
|
1272 |
EN300-31184_1
|
|
CC(C)C(=O)NC(C)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.3
|
8.0
± 0.2
|
1273 |
EN300-358956_1
|
|
Cc1cc(c(=O)[nH]c1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C#N |
−10.9
± 0.3
|
8.0
± 0.2
|
1274 |
EN300-75342_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCn5ccnc5 |
−10.9
± 0.2
|
8.0
± 0.2
|
1275 |
EN300-36096_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CN5CCCNC5=O |
−10.9
± 0.4
|
8.0
± 0.3
|
1276 |
EN300-160080_3
|
|
CS(=O)(=O)c1nnc(s1)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1277 |
EN300-1253178_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NC5CC5 |
−10.9
± 0.1
|
8.0
± 0.1
|
1278 |
EN300-79022_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cccnn5 |
−10.9
± 0.2
|
8.0
± 0.1
|
1279 |
EN300-250836_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CCc5c[nH]nc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1280 |
EN300-35612_3
|
|
CN(CC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)COC |
−10.9
± 0.3
|
8.0
± 0.2
|
1281 |
EN300-331941_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5C[C@H]5C(=O)N |
−10.9
± 0.3
|
8.0
± 0.2
|
1282 |
EN300-141628_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(c5)S(=O)(=O)N |
−10.9
± 0.4
|
8.0
± 0.3
|
1283 |
EN300-124918_3
|
|
Cn1c(=O)[nH]c(n1)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
8.0
± 0.2
|
1284 |
EN300-322332_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5ccc(nc5)C(=O)N |
−10.9
± 0.4
|
8.0
± 0.3
|
1285 |
EN300-97904_1
|
|
CS(=O)(=O)CC1(CC1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.4
|
8.0
± 0.3
|
1286 |
EN300-1696962_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCCn5cnnn5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1287 |
EN300-36158_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5COCCO5 |
−10.9
± 0.2
|
7.9
± 0.1
|
1288 |
EN300-71558_3
|
|
COC(=O)NCCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.3
|
7.9
± 0.2
|
1289 |
EN300-203293_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5CNC(=O)O5 |
−10.9
± 0.2
|
7.9
± 0.1
|
1290 |
JAG-UCB-706446eb-5
|
|
COCCN(C1CCCOC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.3
|
7.9
± 0.2
|
1291 |
EN300-33513_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CSCC(=O)N |
−10.9
± 0.3
|
7.9
± 0.3
|
1292 |
EN300-18569_1
|
|
CC(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−10.9
± 0.2
|
7.9
± 0.2
|
1293 |
EN300-262745_1
|
|
CCn1cc(nn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−10.9
± 0.2
|
7.9
± 0.1
|
1294 |
EN300-139167_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5COCCO5 |
−10.9
± 0.1
|
7.9
± 0.1
|
1295 |
EN300-125140_2
|
|
COCC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
7.9
± 0.2
|
1296 |
EN300-13000_1
|
|
CN(CC(=O)OC)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
7.9
± 0.2
|
1297 |
EN300-113218_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CSC5CCOC5=O |
−10.9
± 0.2
|
7.9
± 0.2
|
1298 |
EN300-157502_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CC5OCCCO5 |
−10.9
± 0.2
|
7.9
± 0.2
|
1299 |
EN300-101796_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccnc(c5)OCCO |
−10.9
± 0.4
|
7.9
± 0.3
|
1300 |
EN300-50009_1
|
|
COC(=O)NCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−10.9
± 0.2
|
7.9
± 0.2
|