| Rank |
Microstate |
SMILES |
ΔG / kcal M-1 |
| 1401 |
EN300-302058_4_1 |
|
CON1CC[C@@H](C1=O)OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
| 1402 |
EN300-36495_1_1 |
|
CCOC(=O)NCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
| 1403 |
EN300-1707980_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)c6[nH]ncn6 |
−7.3
± 0.4
|
| 1404 |
EN300-159869_1_1 |
|
CN([C@@H]1CCCNC1=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
| 1405 |
EN300-37102_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)C5CC5 |
−7.3
± 0.3
|
| 1406 |
EDJ-MED-e4b030d8-1_1
|
|
C[C@@]1(c2cc(ccc2OCC1=O)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.1
|
| 1407 |
EN300-157776_2_3 |
|
C[C@@H]1CN(C[C@H](O1)CO)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.4
|
| 1408 |
DAR-DIA-6a508060-8_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)C5CC5 |
−7.3
± 0.1
|
| 1409 |
EN300-226314_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)[C@H]5CCS(=O)(=O)C5 |
−7.3
± 0.4
|
| 1410 |
EN300-82457_2_1 |
|
CC[NH+](CC)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.5
|
| 1411 |
EN300-82457_2_1 |
|
CC[NH+](CC)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.5
|
| 1412 |
EN300-100768_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6[C@@H](C5)CNC(=O)C6=O |
−7.3
± 0.3
|
| 1413 |
EN300-7466671_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6CCO[C@]6(C5)CO |
−7.3
± 0.4
|
| 1414 |
EN300-6734334_1_1 |
|
Cc1[nH]c(=O)c(cn1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
| 1415 |
EN300-259847_2_2 |
|
CO[C@H]1CCCCN(C1=O)CC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.4
|
| 1416 |
JOH-SUS-a69c159d-7_2
|
|
c1cc2c(cc1F)c(c(nc2F)F)NC(=O)[C@H]3CCOc4c3cc(cc4)Cl |
−7.3
± 0.2
|
| 1417 |
EN300-23129_4_1 |
|
CC(=O)NCCNC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
| 1418 |
EN300-131093_2_2 |
|
C[C@H](C(=O)NCC(=O)C)OC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.4
|
| 1419 |
EN300-6504697_4_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@H]5CC6(CC6)S(=O)(=O)N5 |
−7.3
± 0.4
|
| 1420 |
EN300-321161_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC[NH+]5CCOCC5 |
−7.3
± 0.6
|
| 1421 |
EN300-321161_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC[NH+]5CCOCC5 |
−7.3
± 0.6
|
| 1422 |
EN300-178293_1_1 |
|
C[NH+]1CCN(CC1)C(=O)CCO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
| 1423 |
EN300-50631_2_1 |
|
CN(C)S(=O)(=O)CCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
| 1424 |
EN300-1448603_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H]5CCS(=O)(=O)C5 |
−7.3
± 0.3
|
| 1425 |
EN300-1448603_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H]5CCS(=O)(=O)C5 |
−7.3
± 0.3
|
| 1426 |
EN300-267469_4_1 |
|
CS(=NC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(=O)C |
−7.3
± 0.3
|
| 1427 |
EN300-47657_3_2 |
|
C[C@H](C(=O)N(C)C)NC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
| 1428 |
EN300-248521_2_4 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]([C@H](C5)O)CO |
−7.3
± 0.3
|
| 1429 |
EN300-1968342_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H](CF)O |
−7.3
± 0.4
|
| 1430 |
EN300-1968342_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H](CF)O |
−7.3
± 0.4
|
| 1431 |
EN300-249475_2_1 |
|
CC(=O)NC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
| 1432 |
EN300-37195_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N[C@H]5CCCCNC5=O |
−7.3
± 0.3
|
| 1433 |
EN300-51889_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCC(=O)N5CCC(CC5)O |
−7.3
± 0.4
|
| 1434 |
EN300-724976_3_1 |
|
C[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)[NH+]5CCC(CC5)O |
−7.3
± 0.5
|
| 1435 |
EN300-1081277_3_1 |
|
CNC(=O)CCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.2
± 0.3
|
| 1436 |
EN300-1629199_2_1 |
|
Cc1c(c(nn1C)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)N |
−7.2
± 0.4
|
| 1437 |
EN300-6486576_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5nnc(o5)N6CCOCC6 |
−7.2
± 0.3
|
| 1438 |
EN300-127629_2_1 |
|
C[C@@]1(COCCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−7.2
± 0.3
|
| 1439 |
EN300-310173_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5[C@H](CCO5)Cn6ccnc6 |
−7.2
± 0.3
|
| 1440 |
EN300-47657_1_2 |
|
C[C@H](C(=O)N(C)C)NC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.2
± 0.3
|
| 1441 |
EN300-6255179_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCn5cncn5 |
−7.2
± 0.4
|
| 1442 |
EN300-6255179_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCn5cncn5 |
−7.2
± 0.4
|
| 1443 |
EN300-250593_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C[C@H]5CC(=O)N5 |
−7.2
± 0.2
|
| 1444 |
EN300-52325_2_1 |
|
CCCS(=O)(=O)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.2
± 0.6
|
| 1445 |
DAR-DIA-5ff57136-19_1
|
|
C[NH+](C)C/C=C/C(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−7.2
± 0.3
|
| 1446 |
EN300-261986_4_1 |
|
CS(=O)(=O)[N@]1CC[C@@H](C1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.2
± 0.4
|
| 1447 |
EN300-261986_4_1 |
|
CS(=O)(=O)[N@]1CC[C@@H](C1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.2
± 0.4
|
| 1448 |
EN300-95639_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@H]([C@@H](C5)O)CO |
−7.2
± 0.3
|
| 1449 |
VLA-UCB-34f3ed0c-19_1
|
|
c1ccc2c(c1)cncc2N(C(=O)c3ccco3)C(=O)[C@@H]4CCOc5c4cc(cc5)Cl |
−7.2
± 0.2
|
| 1450 |
ADA-UCB-dc2b944c-8_1
|
|
c1cc2c(cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl)c(c1)Cl |
−7.17
± 0.07
|
| 1451 |
EN300-6735421_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC5(C[NH+](C5)C6CC6)CO |
−7.2
± 0.5
|
| 1452 |
EN300-378316_4_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCc5nnc6n5cc[nH]c6=O |
−7.2
± 0.4
|
| 1453 |
EN300-6501360_3_2 |
|
CN(C)C(=O)NC[C@H](COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−7.2
± 0.5
|
| 1454 |
EN300-02067_2_1 |
|
C[C@@H](COC)NC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.3
|
| 1455 |
EN300-131093_2_1 |
|
C[C@@H](C(=O)NCC(=O)C)OC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.3
|
| 1456 |
JOH-SUS-a69c159d-6_2
|
|
c1ccc2c(c1)c(c(nc2F)F)NC(=O)[C@H]3CCOc4c3cc(cc4)Cl |
−7.1
± 0.2
|
| 1457 |
EN300-73102_2_2 |
|
C[C@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C5CCOCC5 |
−7.1
± 0.5
|
| 1458 |
EN300-70092_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@H](C5)C(=O)N |
−7.1
± 0.4
|
| 1459 |
EN300-90142_2_4 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5CCC[C@H](C5)C(=O)N |
−7.1
± 0.2
|
| 1460 |
EN300-69215_2_1 |
|
CN(C)C(=O)CCCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.4
|
| 1461 |
EN300-6732769_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)[C@@H]6CC(=O)NC6=O |
−7.1
± 0.3
|
| 1462 |
EN300-1087187_1_4 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6CCC(=O)N[C@H]6C5 |
−7.1
± 0.4
|
| 1463 |
EN300-39005_2_1 |
|
CN(CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)OC |
−7.1
± 0.3
|
| 1464 |
EN300-47657_2_2 |
|
C[C@H](C(=O)N(C)C)NC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.4
|
| 1465 |
EN300-185398_3_1 |
|
C[C@@H](C(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(F)F)O |
−7.1
± 0.2
|
| 1466 |
EN300-16091_2_1 |
|
CCS(=O)(=O)[N@@]1CCC[C@@H]1C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.4
|
| 1467 |
EN300-96886_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@@H](C[C@@H](C5)O)O |
−7.1
± 0.3
|
| 1468 |
EN300-7355737_4_1 |
|
Cn1cc(c(n1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)N |
−7.1
± 0.6
|
| 1469 |
EN300-2009111_2_1 |
|
Cn1c(cc(n1)CO)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.3
|
| 1470 |
EN300-204419_2_1 |
|
C[C@@H](CO)N(C)C(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.3
|
| 1471 |
DAR-DIA-0d514e7d-5_1
|
|
C[C@H]1COc2c(cc(cc2NC3CCCC3)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.2
|
| 1472 |
JOH-SUS-a69c159d-4_1
|
|
c1ccc2c(c1)c(cnc2C(F)(F)F)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−7.1
± 0.1
|
| 1473 |
EN300-135078_2_1 |
|
CCN1CCN(CC1=O)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.3
|
| 1474 |
EN300-1693852_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]([C@@H](C5)F)CO |
−7.1
± 0.3
|
| 1475 |
EN300-218962_2_1 |
|
CC[C@@H](C(=O)N)NC(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.2
|
| 1476 |
EN300-1703852_1_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@H]5COC(=O)N5 |
−7.1
± 0.5
|
| 1477 |
EN300-36850_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCNC(=O)C5CC5 |
−7.1
± 0.2
|
| 1478 |
EN300-306144_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)(CO)CO |
−7.1
± 0.3
|
| 1479 |
EN300-266565_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5CC(C5)C(=O)N |
−7.0
± 0.3
|
| 1480 |
EN300-60035_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCCNC5=O |
−7.0
± 0.3
|
| 1481 |
EN300-60035_2_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCCNC5=O |
−7.0
± 0.3
|
| 1482 |
EN300-250458_2_1 |
|
Cn1c(ccn1)[C@@H](CO)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.4
|
| 1483 |
EN300-2008102_4_2 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@H]5CN6C[C@@H](O5)CCC6=O |
−7.0
± 0.7
|
| 1484 |
EN300-82457_1_1 |
|
CC[NH+](CC)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.3
|
| 1485 |
EN300-82457_1_1 |
|
CC[NH+](CC)CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.3
|
| 1486 |
EN300-66432_1_1 |
|
CN(C)S(=O)(=O)CCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.3
|
| 1487 |
EN300-178293_4_1 |
|
C[NH+]1CCN(CC1)C(=O)CCOCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.5
|
| 1488 |
EN300-31213_2_2 |
|
CCS(=O)(=O)N[C@H](C)C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.5
|
| 1489 |
EN300-384241_2_1 |
|
Cc1[nH]nc(n1)C2CN(C2)C(=O)CC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−7.0
± 0.3
|
| 1490 |
EN300-6497238_2_1 |
|
C[C@@H]1CS(=O)(=O)CCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.4
|
| 1491 |
EN300-82539_1_1 |
|
CCOC(=O)C[C@@H](CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−7.0
± 0.4
|
| 1492 |
EN300-82539_1_1 |
|
CCOC(=O)C[C@@H](CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−7.0
± 0.4
|
| 1493 |
EN300-6491697_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCc5cccc(=O)[nH]5 |
−7.0
± 0.3
|
| 1494 |
EN300-703023_2_1 |
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CCC(=O)N[C@H]5C[C@@H](C5)CO)cc1 |
−7.0
± 0.3
|
| 1495 |
MAK-UNK-83e0a0b4-4_2
|
|
CCCCc1ccc2c(c1)[C@H](CCO2)C(=O)N(CCNC3C[NH2+]C3)c4cncc5c4cccc5 |
−7.0
± 0.4
|
| 1496 |
ADA-UCB-dc2b944c-7_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)F |
−7.00
± 0.06
|
| 1497 |
EN300-6495717_2_1 |
|
C[C@@H]1CC(CN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)(CO)CO |
−7.0
± 0.5
|
| 1498 |
EN300-343103_2_1 |
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCc5[nH]c(=O)c6c(n5)CCOC6 |
−7.0
± 0.3
|
| 1499 |
EN300-6356960_2_1 |
|
Cn1cnnc1CCCC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.4
|
| 1500 |
EN300-311771_2_1 |
|
c1cc2c(c(cnc2)NC(=O)[C@]3(c4c(ccc(c4)Cl)OCC3)CCC(=O)N[C@H]5C[C@@H](C5)C(=O)N)cc1 |
−7.0
± 0.3
|