| Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
| 1001 |
EN300-312850_1
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N(C)C |
−7.7
± 0.4
|
5.6
± 0.3
|
| 1002 |
EN300-258081_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)OCCO |
−7.7
± 0.3
|
5.6
± 0.2
|
| 1003 |
EN300-1448603_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5CCS(=O)(=O)C5 |
−7.7
± 0.2
|
5.6
± 0.2
|
| 1004 |
EN300-70092_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)C(=O)N |
−7.6
± 0.3
|
5.6
± 0.2
|
| 1005 |
EN300-99161_2
|
|
CC1(CCN(C1)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−7.6
± 0.2
|
5.6
± 0.2
|
| 1006 |
EN300-182725_2
|
|
CC(C(C)S(=O)(=O)C)C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.6
± 0.4
|
5.6
± 0.3
|
| 1007 |
JAG-UCB-706446eb-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC5CCCOC5 |
−7.6
± 0.2
|
5.6
± 0.2
|
| 1008 |
EN300-47046_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)N5CCN(CC5)C(=O)C6CC6 |
−7.6
± 0.3
|
5.6
± 0.2
|
| 1009 |
EN300-36522_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CNC(=O)C5CC5 |
−7.6
± 0.3
|
5.6
± 0.2
|
| 1010 |
EN300-7539819_2
|
|
CC1(C[C@H]([C@H](CN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O)O)C |
−7.6
± 0.3
|
5.6
± 0.2
|
| 1011 |
EN300-1717630_2
|
|
CC1(CCN1C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−7.6
± 0.3
|
5.6
± 0.2
|
| 1012 |
EN300-22884_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCNC(=O)C5 |
−7.6
± 0.3
|
5.6
± 0.2
|
| 1013 |
EN300-79588_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCCS(=O)(=O)N |
−7.6
± 0.2
|
5.5
± 0.1
|
| 1014 |
EN300-28113_2
|
|
CC(C(=O)N1CCC(CC1)C(=O)N)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.6
± 0.3
|
5.5
± 0.2
|
| 1015 |
EN300-248521_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C(C5)O)CO |
−7.6
± 0.5
|
5.5
± 0.3
|
| 1016 |
EN300-7435545_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CCO[C@@H]5C(=O)N |
−7.6
± 0.4
|
5.5
± 0.3
|
| 1017 |
EN300-45485_1
|
|
CS(=O)(=O)NCCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.6
± 0.3
|
5.5
± 0.2
|
| 1018 |
EN300-47657_3
|
|
CC(C(=O)N(C)C)NC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.6
± 0.3
|
5.5
± 0.2
|
| 1019 |
EN300-254840_2
|
|
CC(C1CN(CCO1)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−7.6
± 0.4
|
5.5
± 0.3
|
| 1020 |
EDJ-MED-e4b030d8-3
|
|
C[C@H]1C[C@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.57
± 0.07
|
5.51
± 0.05
|
| 1021 |
EN300-302058_4
|
|
CON1CCC(C1=O)OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.6
± 0.3
|
5.5
± 0.2
|
| 1022 |
JOH-UNI-f51e3bbc-4
|
|
COc1c(c2ccccc2cn1)NC(=O)C3CCOc4c3cc(cc4)Cl |
−7.6
± 0.1
|
5.51
± 0.09
|
| 1023 |
EN300-35592_3
|
|
Cn1cc(cc1C(=O)N)C(=O)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.6
± 0.3
|
5.5
± 0.3
|
| 1024 |
EN300-97938_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@H]([C@H](C5)O)O |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1025 |
EN300-741926_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C(C5)F)O |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1026 |
EN300-18292_2
|
|
CN1CCN(CC1)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1027 |
EN300-1722713_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC6(C5)CC(=O)NC6 |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1028 |
EN300-132624_1
|
|
CCC(=O)CNC(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.5
± 0.4
|
5.5
± 0.3
|
| 1029 |
EN300-77520_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COC5CCOCC5 |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1030 |
EN300-48680_2
|
|
CNC(=O)C1CCN(CC1)C(=O)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.5
± 0.4
|
5.5
± 0.3
|
| 1031 |
EN300-7444950_2
|
|
COc1cc(ncn1)CC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.5
± 0.4
|
5.5
± 0.3
|
| 1032 |
EN300-301690_4
|
|
CS(=O)(=O)N1CCC(C1)OCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1033 |
EN300-1072972_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCOC5=O |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1034 |
EN300-23221_3
|
|
CC(C)NC(=O)CNC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1035 |
EN300-28340_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCC(=O)N5CCCC5 |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1036 |
EN300-180575_1
|
|
CC1CCS(=O)(=O)CCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.5
± 0.4
|
5.5
± 0.3
|
| 1037 |
EN300-79588_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCCS(=O)(=O)N |
−7.5
± 0.3
|
5.5
± 0.2
|
| 1038 |
MAK-UNK-8be7dca9-3
|
|
c1ccc2c(c1)cncc2NC(=O)C3c4cc(ccc4OCC3CN)Cl |
−7.5
± 0.1
|
5.47
± 0.08
|
| 1039 |
EN300-59879_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCC(CC5)CO |
−7.5
± 0.4
|
5.5
± 0.3
|
| 1040 |
EN300-216916_1
|
|
CN(C)CC(CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−7.5
± 0.5
|
5.5
± 0.4
|
| 1041 |
EN300-304627_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5[C@H](CCO5)Cn6cccn6 |
−7.5
± 0.4
|
5.5
± 0.3
|
| 1042 |
EN300-08259_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)NCCCN5CCCC5=O |
−7.5
± 0.4
|
5.4
± 0.3
|
| 1043 |
JOH-SUS-a69c159d-1
|
|
Cc1c2ccccc2c(cn1)NC(=O)C3CCOc4c3cc(cc4)Cl |
−7.47
± 0.10
|
5.44
± 0.07
|
| 1044 |
EN300-304771_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCN(C5=O)C6CC6 |
−7.5
± 0.4
|
5.4
± 0.3
|
| 1045 |
EN300-781107_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)(CO)O |
−7.5
± 0.4
|
5.4
± 0.3
|
| 1046 |
EN300-259849_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CN5CCCCC(C5=O)O |
−7.5
± 0.7
|
5.4
± 0.5
|
| 1047 |
EN300-45436_1
|
|
CCS(=O)(=O)NCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.5
± 0.4
|
5.4
± 0.3
|
| 1048 |
EN300-7459916_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COC(=O)CO |
−7.5
± 0.2
|
5.4
± 0.2
|
| 1049 |
EN300-48902_3
|
|
CNC(=O)C1CCCN1C(=O)COCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.5
± 0.6
|
5.4
± 0.4
|
| 1050 |
EN300-95598_1
|
|
Cn1cc(cn1)S(=O)(=O)NCCO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.4
± 0.5
|
5.4
± 0.3
|
| 1051 |
EN300-175487_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCO[C@@H](C5)CO |
−7.4
± 0.4
|
5.4
± 0.3
|
| 1052 |
EN300-67573_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC(=O)NC5CCOCC5 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1053 |
EN300-23223_2
|
|
CNC(=O)CNC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1054 |
EN300-40153_2
|
|
CN(CC(=O)N)C(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1055 |
EN300-761618_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC(=O)Nc5cccnn5 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1056 |
EN300-1724997_2
|
|
CN1CCN(C(C1=O)CO)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1057 |
DAR-DIA-0d514e7d-10
|
|
C[C@H]1COc2c(cc(cc2Nc3cnn(c3)C)Cl)[C@@H]1C(=O)Nc4cncc5c4cccc5 |
−7.4
± 0.2
|
5.4
± 0.2
|
| 1058 |
EN300-97746_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)C5CCOCC5 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1059 |
EN300-256053_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC(C5)CO |
−7.4
± 0.2
|
5.4
± 0.1
|
| 1060 |
EN300-178288_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC6CC6(C5)O |
−7.4
± 0.4
|
5.4
± 0.3
|
| 1061 |
EN300-7438227_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)C5(CCC5)CCS(=O)(=O)N |
−7.4
± 0.5
|
5.4
± 0.4
|
| 1062 |
EN300-73582_2
|
|
CCS(=O)(=O)NCCOC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.3
|
5.4
± 0.3
|
| 1063 |
EN300-45182_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCN5CCOC5=O |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1064 |
EN300-7472244_2
|
|
CO[C@@H]1C[C@H](N(C1)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)CO |
−7.4
± 0.4
|
5.4
± 0.3
|
| 1065 |
EN300-2011083_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5CCC(=O)OCC5 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1066 |
EN300-210084_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CC5CCCC(=O)N5 |
−7.4
± 0.4
|
5.4
± 0.3
|
| 1067 |
EN300-05754_1
|
|
CC(C(=O)N1CCOCC1)O[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1068 |
EN300-42154_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CS(=O)(=O)C5CCCC5 |
−7.4
± 0.5
|
5.4
± 0.4
|
| 1069 |
EN300-7473032_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCNC(=O)C5C(=O)N |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1070 |
EN300-1865348_2
|
|
CN(C)CCOCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.5
|
5.4
± 0.3
|
| 1071 |
EN300-1708620_2
|
|
CN(C)CCSCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.3
|
5.4
± 0.2
|
| 1072 |
EN300-1270211_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5C[C@]6(C[C@]6(C5)CO)CO |
−7.4
± 0.4
|
5.4
± 0.3
|
| 1073 |
EN300-45485_2
|
|
CS(=O)(=O)NCCCOC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.4
|
5.4
± 0.3
|
| 1074 |
EN300-70522_2
|
|
CS(=O)(=O)CCCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.4
|
5.4
± 0.3
|
| 1075 |
EN300-129455_2
|
|
CCNC(=O)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.4
± 0.3
|
5.4
± 0.3
|
| 1076 |
EN300-6482634_1
|
|
CC1CN(CC(=O)N1C)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
5.4
± 0.2
|
| 1077 |
EN300-36495_1
|
|
CCOC(=O)NCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
5.4
± 0.2
|
| 1078 |
EN300-1707980_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC(C5)c6[nH]cnn6 |
−7.3
± 0.4
|
5.3
± 0.3
|
| 1079 |
EN300-159869_1
|
|
CN(C1CCCNC1=O)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1080 |
EN300-37102_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N(CCO)C5CC5 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1081 |
EDJ-MED-e4b030d8-1
|
|
C[C@@]1(c2cc(ccc2OCC1=O)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.1
|
5.34
± 0.09
|
| 1082 |
EN300-157776_2
|
|
CC1CN(CC(O1)CO)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.4
|
5.3
± 0.3
|
| 1083 |
EN300-82457_2
|
|
CCN(CC)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1084 |
EN300-100768_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN6C(C5)CNC(=O)C6=O |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1085 |
EN300-7466671_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6CCO[C@]6(C5)CO |
−7.3
± 0.4
|
5.3
± 0.3
|
| 1086 |
EN300-6734334_1
|
|
Cc1[nH]cc(c(=O)n1)CCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1087 |
DAR-DIA-6a508060-13
|
|
CS(=O)(=O)NCCC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1088 |
EN300-23129_4
|
|
CC(=O)NCCNC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1089 |
EN300-6504697_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCC5CC6(CC6)S(=O)(=O)N5 |
−7.3
± 0.4
|
5.3
± 0.3
|
| 1090 |
EN300-321161_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOCCN5CCOCC5 |
−7.3
± 0.5
|
5.3
± 0.3
|
| 1091 |
EN300-178293_1
|
|
CN1CCN(CC1)C(=O)CCO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1092 |
EN300-113218_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CSC5CCOC5=O |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1093 |
EN300-50631_2
|
|
CN(C)S(=O)(=O)CCC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1094 |
EN300-267469_4
|
|
CS(=NC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(=O)C |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1095 |
EN300-249475_2
|
|
CC(=O)NC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.3
|
5.3
± 0.2
|
| 1096 |
EN300-51889_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCC(=O)N5CCC(CC5)O |
−7.3
± 0.4
|
5.3
± 0.3
|
| 1097 |
VLA-UCB-1dbca3b4-14
|
|
CC1(c2cc(ccc2OCC1=O)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.3
± 0.1
|
5.28
± 0.07
|
| 1098 |
EN300-1081277_3
|
|
CNC(=O)CCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.2
± 0.3
|
5.3
± 0.2
|
| 1099 |
MAK-UNK-8be7dca9-9
|
|
c1cc2c(cc1C(=O)O)cncc2NC(=O)C3CCOc4c3cc(cc4)Cl |
−7.24
± 0.08
|
5.28
± 0.06
|
| 1100 |
EN300-1629199_2
|
|
Cc1c(c(nn1C)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)S(=O)(=O)N |
−7.2
± 0.4
|
5.3
± 0.3
|