Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
5701 |
EN300-29617_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CN5C(=O)N6CCCCCC6N5 |
−6.8
± 0.4
|
5.0
± 0.3
|
5702 |
KAD-UNI-8a629cb0-10
|
|
CC(=O)N1C[C@@H]2C[C@H]1CN2C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.8
± 0.3
|
5.0
± 0.2
|
5703 |
EDJ-MED-4c7486ba-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn[nH]c5S(=O)(=O)N |
−6.8
± 0.3
|
5.0
± 0.2
|
5704 |
EN300-52380_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)CC(=O)N |
−6.8
± 0.2
|
5.0
± 0.2
|
5705 |
MAT-POS-bb423b95-9
|
|
c1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2cccc3Cl |
−6.8
± 0.3
|
5.0
± 0.2
|
5706 |
EDJ-MED-d08626de-3
|
|
CO[C@@]1(CCOc2c1cc(c(c2)Cl)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.8
± 0.4
|
5.0
± 0.3
|
5707 |
RAL-THA-2d450e86-7
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3ccc(cc3)F |
−6.8
± 0.2
|
5.0
± 0.2
|
5708 |
DAR-DIA-0d514e7d-35
|
|
C[C@H]1[C@@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.8
± 0.3
|
5.0
± 0.2
|
5709 |
EN300-23318_2_2
|
|
C[C@H](C(=O)N[C@@H]1CCS(=O)(=O)C1)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.8
± 0.4
|
5.0
± 0.3
|
5710 |
EN300-180532_1_2
|
|
C[C@H]1CN(CCS(=O)(=O)C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.8
± 0.4
|
5.0
± 0.3
|
5711 |
EN300-307008_2_1
|
|
CN1[C@@H](CNC1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.8
± 0.3
|
5.0
± 0.2
|
5712 |
MAT-POS-f9802937-2
|
|
CN1c2ccc(cc2C(CC1=O)(C(=O)Nc3cncc4c3cccc4)O)Cl |
−6.8
± 0.3
|
5.0
± 0.2
|
5713 |
NAU-LAT-a5c7d7cb-2
|
|
CC(=O)N1CCN(CC1)C(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.8
± 0.4
|
5.0
± 0.3
|
5714 |
RAL-THA-2d450e86-23
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cccc(c3F)F |
−6.8
± 0.3
|
5.0
± 0.2
|
5715 |
EN300-393148_2_1
|
|
C[N@]1[C@@H](CCS1(=O)=O)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.8
± 0.3
|
5.0
± 0.2
|
5716 |
EN300-21009_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5CCCO5 |
−6.8
± 0.2
|
5.0
± 0.1
|
5717 |
RAL-THA-2d450e86-3
|
|
Cc1ccc(cc1)CC(=O)Nc2cncc3c2cccc3 |
−6.8
± 0.3
|
4.9
± 0.2
|
5718 |
RAL-THA-05e671eb-3
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3ccc(c4)Cl |
−6.8
± 0.2
|
4.9
± 0.1
|
5719 |
EN300-1448674_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H]5CCn6c(ncn6)C5 |
−6.8
± 0.3
|
4.9
± 0.2
|
5720 |
EN300-341337_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@]56CCO[C@@H]5CCOC6 |
−6.8
± 0.2
|
4.9
± 0.1
|
5721 |
EN300-1709315_2_2
|
|
C[C@]1(CCCNS1(=O)=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.8
± 0.3
|
4.9
± 0.2
|
5722 |
LON-WEI-5e7d1b3e-18
|
|
Cn1cc(c2ccccc2c1=O)NC(=O)Nc3ccc(cc3OC)OC |
−6.8
± 0.6
|
4.9
± 0.4
|
5723 |
EN300-172020_2_1
|
|
Cn1cc(cn1)C[C@@H](C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−6.8
± 0.2
|
4.9
± 0.2
|
5724 |
EN300-74856_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@H]5CCCS(=O)(=O)C5 |
−6.7
± 0.3
|
4.9
± 0.2
|
5725 |
EN300-7456641_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6c(nn5)CCOC6 |
−6.7
± 0.3
|
4.9
± 0.3
|
5726 |
EN300-215852_2_1
|
|
CCn1nc(c(n1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−6.7
± 0.3
|
4.9
± 0.2
|
5727 |
LON-WEI-4d77710c-27
|
|
CC(C)Cn1cc(c2ccccc2c1=O)NC(=O)NC3CCCCCC3 |
−6.7
± 0.4
|
4.9
± 0.3
|
5728 |
RAL-THA-1d44ff04-5
|
|
CNC(=O)c1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2cccc3 |
−6.7
± 0.3
|
4.9
± 0.2
|
5729 |
EDJ-MED-4c7486ba-3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cc5cnc[nH]5 |
−6.7
± 0.3
|
4.9
± 0.2
|
5730 |
JOH-SUS-a69c159d-4
|
|
c1ccc2c(c1)c(cnc2C(F)(F)F)NC(=O)C3CCOc4c3cc(cc4)Cl |
−6.7
± 0.1
|
4.89
± 0.10
|
5731 |
EN300-68735_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@H](C5)[NH+]6CCOCC6 |
−6.7
± 0.4
|
4.9
± 0.3
|
5732 |
EN300-190026_1_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@H](CO)[C@H]5CCCO5 |
−6.7
± 0.4
|
4.9
± 0.3
|
5733 |
EN300-14405_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6n(c5=O)CCS6 |
−6.7
± 0.3
|
4.9
± 0.2
|
5734 |
LAU-MED-88a3970a-6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3CCOc4c3cc(cc4CCCO)Cl |
−6.7
± 0.3
|
4.9
± 0.2
|
5735 |
EN300-57990_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5[nH]nnn5 |
−6.7
± 0.3
|
4.9
± 0.2
|
5736 |
LON-WEI-4d77710c-52
|
|
Cn1cc(c2ccccc2c1=O)NC(=O)NCCc3ccc(cc3)Cl |
−6.7
± 0.4
|
4.9
± 0.3
|
5737 |
LON-WEI-5e7d1b3e-54
|
|
CC(C)Cn1cc(c2ccccc2c1=O)NC(=O)N3CCC(CC3)Cc4ccccc4 |
−6.7
± 0.5
|
4.9
± 0.4
|
5738 |
EN300-246808_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@H]5CCCS5(=O)=O |
−6.7
± 0.6
|
4.9
± 0.4
|
5739 |
JOH-SUS-a69c159d-3
|
|
c1ccc2c(c1)c(cnc2C(F)F)NC(=O)C3CCOc4c3cc(cc4)Cl |
−6.7
± 0.1
|
4.87
± 0.10
|
5740 |
EN300-781107_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@](C5)(CO)O |
−6.7
± 0.4
|
4.9
± 0.3
|
5741 |
RAL-THA-8416115c-11
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCN(c4c3cc(cc4)Cl)Cc5cnc[nH]5 |
−6.7
± 0.3
|
4.9
± 0.2
|
5742 |
EN300-83527_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc6ncccn6n5 |
−6.7
± 0.2
|
4.9
± 0.2
|
5743 |
EN300-345754_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCOC[C@H]5CCO |
−6.7
± 0.3
|
4.9
± 0.2
|
5744 |
NIR-THE-590dedc7-1
|
|
CC(=O)N1CCN(CC1)C(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.7
± 0.4
|
4.9
± 0.3
|
5745 |
ALP-POS-6747fa38-1
|
|
CC(=O)N1CCN(CC1)CC(=O)Nc2cncc3c2cccc3 |
−6.7
± 0.5
|
4.9
± 0.3
|
5746 |
ALP-UNI-0676e700-22
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnc6cc[nH]n6c5=O |
−6.7
± 0.3
|
4.9
± 0.2
|
5747 |
EN300-60862_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCO[C@@H](C5)C(=O)N |
−6.7
± 0.3
|
4.9
± 0.2
|
5748 |
EN300-1071940_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C[C@@]5(CCCOC5)O |
−6.7
± 0.2
|
4.8
± 0.2
|
5749 |
EN300-304695_2_2
|
|
CN1CCCC[C@H](C1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.7
± 0.3
|
4.8
± 0.2
|
5750 |
JOH-UNI-a38a7bdd-1
|
|
c1ccc2c(c1)cncc2N(C(=O)Cc3cccc(c3)Cl)C(=O)C(F)(F)F |
−6.7
± 0.3
|
4.8
± 0.2
|
5751 |
EN300-07676_2_1
|
|
c1ccc(cc1)CC(=O)NCC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.7
± 0.2
|
4.8
± 0.1
|
5752 |
RAL-THA-05e671eb-22
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3cccc4F |
−6.65
± 0.10
|
4.84
± 0.07
|
5753 |
MAT-POS-bb423b95-7
|
|
CN(c1cncc2c1cccc2)C(=O)Cc3cccc(c3)Cl |
−6.64
± 0.09
|
4.84
± 0.07
|
5754 |
EN300-248618_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)CS(=O)(=O)C5CC5 |
−6.6
± 0.4
|
4.8
± 0.3
|
5755 |
EN300-7459545_2_2
|
|
C[NH+](C)C[C@](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(C(F)(F)F)O |
−6.6
± 0.4
|
4.8
± 0.3
|
5756 |
RAL-THA-2d450e86-36
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3ccccc3Cl |
−6.6
± 0.3
|
4.8
± 0.2
|
5757 |
EN300-1587757_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CCCNS5(=O)=O |
−6.6
± 0.3
|
4.8
± 0.2
|
5758 |
MIC-UNK-cdc2493e-17
|
|
CC(=O)N1CCC(CC1)N(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.6
± 0.4
|
4.8
± 0.3
|
5759 |
MAT-POS-2905de8c-3
|
|
CN(C)C1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.6
± 0.5
|
4.8
± 0.3
|
5760 |
EN300-260284_2_1
|
|
Cn1c(c[nH]c1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.6
± 0.2
|
4.8
± 0.1
|
5761 |
MAT-POS-b5746674-37
|
|
Cn1cc(c2ccccc2c1=O)NC(=O)N(Cc3ccco3)CC4CCCO4 |
−6.6
± 0.5
|
4.8
± 0.3
|
5762 |
ALP-POS-d3acb8cc-2
|
|
C[C@@H]1C[C@@H](c2cc(ccc2O1)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.6
± 0.2
|
4.8
± 0.2
|
5763 |
RAL-THA-05e671eb-33
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3c(ccc4)F |
−6.6
± 0.1
|
4.81
± 0.10
|
5764 |
MIC-UNK-cdc2493e-9
|
|
CC(=O)NC1CCC(CC1)N(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.6
± 0.5
|
4.8
± 0.4
|
5765 |
EN300-2908024_4_1
|
|
CC[C@@](C)(C(=O)N)C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.6
± 0.4
|
4.8
± 0.3
|
5766 |
EDJ-MED-d203f206-27
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@H](C5)CNC(=O)N |
−6.6
± 0.3
|
4.8
± 0.2
|
5767 |
EN300-1707879_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CNC(=O)C[C@@]56CCOC6 |
−6.6
± 0.2
|
4.8
± 0.1
|
5768 |
EN300-300825_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(CCOCC5)CCO |
−6.6
± 0.3
|
4.8
± 0.2
|
5769 |
EN300-114526_2_1
|
|
Cc1c(c([nH]n1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−6.6
± 0.2
|
4.8
± 0.1
|
5770 |
EN300-6491795_2_1
|
|
C[C@@H]1C2(CC(C2)(O1)CO)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.6
± 0.3
|
4.8
± 0.2
|
5771 |
MAK-UNK-ffc90da7-4
|
|
CC(CNCC1CCCO1)C(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.6
± 0.3
|
4.8
± 0.2
|
5772 |
MAK-UNK-8be7dca9-6
|
|
c1cc(c2cncc(c2c1)NC(=O)C3CCOc4c3cc(cc4)Cl)CN |
−6.6
± 0.1
|
4.79
± 0.10
|
5773 |
KAD-UNI-8a629cb0-5
|
|
Cn1c(nnn1)C2CCN(CC2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.6
± 0.4
|
4.8
± 0.3
|
5774 |
ALF-EVA-ced740bd-3
|
|
c1cc2cncc(c2cc1F)NC(=O)C3COc4c3cc(cc4)F |
−6.6
± 0.2
|
4.8
± 0.1
|
5775 |
ALP-UNI-4b8a177c-1
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3c(ccc4O)Cl |
−6.6
± 0.2
|
4.8
± 0.1
|
5776 |
MAT-POS-3b92565d-7
|
|
Cn1cc(c2ccccc2c1=O)NC(=O)Cc3cc(ccc3OC)Cl |
−6.6
± 0.3
|
4.8
± 0.2
|
5777 |
RAL-THA-2d450e86-38
|
|
Cc1ccccc1CC(=O)Nc2cncc3c2cccc3 |
−6.5
± 0.2
|
4.8
± 0.2
|
5778 |
MAT-POS-1f3f1a6f-2
|
|
CN(C)C(c1ccc(c(c1)Cl)Cl)C(=O)Nc2cncc3c2cccc3 |
−6.5
± 0.3
|
4.8
± 0.2
|
5779 |
EDJ-MED-40433386-6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@]56CCO[C@H]5CCOC6 |
−6.5
± 0.2
|
4.8
± 0.1
|
5780 |
EN300-188217_4_1
|
|
CC(C)(CS(=O)(=O)C)C(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.5
± 0.4
|
4.8
± 0.3
|
5781 |
ADA-UCB-dc2b944c-13
|
|
C[C@@H]1COc2ccc(cc2[C@H]1C(=O)Nc3cncc4c3cccc4)Cl |
−6.5
± 0.2
|
4.8
± 0.2
|
5782 |
MAK-UNK-919546f0-4
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3ccccc3O |
−6.5
± 0.3
|
4.7
± 0.2
|
5783 |
MAT-POS-8a69d52e-6
|
|
C[C@@H]1COc2ccc(cc2[C@H]1C(=O)Nc3cncc4c3cccc4)Cl |
−6.5
± 0.2
|
4.7
± 0.2
|
5784 |
MIC-UNK-cdc2493e-18
|
|
CC(=O)N1CCC(C1)N(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.5
± 0.2
|
4.7
± 0.2
|
5785 |
EN300-6760451_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5[nH]nc6[n+]5cccc6 |
−6.5
± 0.2
|
4.7
± 0.2
|
5786 |
MAT-POS-b3e365b9-2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3CCOc4c3cc(cc4)Cl |
−6.5
± 0.2
|
4.7
± 0.2
|
5787 |
EN300-386187_1_1
|
|
COC(=O)N[C@H]1CCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.5
± 0.3
|
4.7
± 0.2
|
5788 |
MAT-POS-8e4737f4-1
|
|
C[C@@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.50
± 0.10
|
4.74
± 0.07
|
5789 |
EDG-MED-971238d3-5
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CN |
−6.5
± 0.3
|
4.7
± 0.2
|
5790 |
EN300-7351945_2_1
|
|
CC1(C[C@@H](CNC1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−6.5
± 0.2
|
4.7
± 0.2
|
5791 |
JOH-UNI-f51e3bbc-3
|
|
c1ccc2c(c1)cnc(c2NC(=O)C3CCOc4c3cc(cc4)Cl)O |
−6.5
± 0.1
|
4.7
± 0.1
|
5792 |
RAL-THA-05e671eb-23
|
|
COc1cccc2c1OCCC2C(=O)Nc3cncc4c3cccc4 |
−6.5
± 0.1
|
4.72
± 0.10
|
5793 |
EDJ-MED-8c98ee63-2
|
|
Cn1ccc(n1)CNCC2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.5
± 0.3
|
4.7
± 0.2
|
5794 |
RAL-THA-05e671eb-32
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3c(ccc4)Cl |
−6.5
± 0.1
|
4.72
± 0.08
|
5795 |
EN300-395954_2_2
|
|
C[C@]12CN(CCN1C(=O)OC2)C(=O)CC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−6.5
± 0.3
|
4.7
± 0.2
|
5796 |
EN300-174561_2_1
|
|
Cn1cncc1CCC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.5
± 0.2
|
4.7
± 0.1
|
5797 |
DAR-DIA-076fb6ea-8
|
|
C=C=CC(=O)N(c1cncc2c1cccc2)C(=O)Cc3cccc(c3)Cl |
−6.5
± 0.4
|
4.7
± 0.3
|
5798 |
EDG-MED-90036822-10
|
|
C[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)N |
−6.5
± 0.3
|
4.7
± 0.2
|
5799 |
EN300-366852_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@H](C5)c6[nH]nnn6 |
−6.5
± 0.3
|
4.7
± 0.2
|
5800 |
EDG-MED-5d232de5-5
|
|
CN1CC[C@@H](c2c1ccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.5
± 0.3
|
4.7
± 0.2
|