Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
5601 |
NAU-LAT-2fed8305-9
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(co3)Cl |
−7.1
± 0.2
|
5.2
± 0.2
|
5602 |
MAT-POS-2492181e-4
|
|
CC(C)Cn1cc(c2ccccc2c1=O)NC(=O)NCCc3ccc(cc3)Cl |
−7.1
± 0.6
|
5.2
± 0.4
|
5603 |
EN300-124301_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CCCn5ccnn5 |
−7.1
± 0.2
|
5.2
± 0.2
|
5604 |
EDG-MED-5d232de5-4
|
|
CC(=O)N1CC[C@@H](c2c1ccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.3
|
5.2
± 0.2
|
5605 |
EN300-1706036_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H]5C(=O)NCCO5 |
−7.1
± 0.4
|
5.2
± 0.3
|
5606 |
EN300-84186_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC(CO)CO |
−7.1
± 0.4
|
5.2
± 0.3
|
5607 |
RAL-THA-2d450e86-13
|
|
Cc1cccc(c1)CC(=O)Nc2cncc3c2cccc3 |
−7.1
± 0.2
|
5.2
± 0.2
|
5608 |
PET-UNK-b87f07d0-2
|
|
C[C@H](CCc1cc(cc(c1)Cl)CC(=O)Nc2cncc3c2cccc3)NC(=O)C |
−7.1
± 0.4
|
5.2
± 0.3
|
5609 |
EN300-260760_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NCc5cc(=O)[nH][nH]5 |
−7.1
± 0.2
|
5.2
± 0.2
|
5610 |
EN300-313440_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5C[NH+](C5)C6CCOCC6 |
−7.1
± 0.4
|
5.2
± 0.3
|
5611 |
EDJ-MED-ee07cf00-7
|
|
Cc1c(c(=O)ccn1CC(=O)NC(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−7.1
± 0.4
|
5.2
± 0.3
|
5612 |
EN300-101291_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(c(=O)[nH]c5=O)CCO |
−7.1
± 0.3
|
5.2
± 0.2
|
5613 |
RAL-THA-2d450e86-35
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cnc3)F |
−7.1
± 0.2
|
5.2
± 0.2
|
5614 |
ED_-GRI-5b13fbe2-52
|
|
CC(CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)(c5cn(nn5)CC6CC6)N |
−7.1
± 0.2
|
5.2
± 0.2
|
5615 |
EN300-258702_2_1
|
|
Cn1ccc(n1)CC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.3
|
5.2
± 0.2
|
5616 |
NAU-LAT-30527ac5-4
|
|
CC(=O)NCCc1c[nH]c2c1cc(cc2CC(=O)Nc3cncc4c3cccc4)Cl |
−7.1
± 0.5
|
5.2
± 0.4
|
5617 |
MIC-UNK-5a93dd5f-6
|
|
CC(=O)N(C)C1CCN(CC1)C(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.4
|
5.2
± 0.3
|
5618 |
EN300-70431_2_1
|
|
COc1c(c(ncn1)OC)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.2
|
5.2
± 0.2
|
5619 |
EN300-137784_4_1
|
|
CC1CCN(CC1)C(=O)C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.3
|
5.2
± 0.2
|
5620 |
EN300-124164_2_1
|
|
COCCN1CCN(CC1=O)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.1
± 0.3
|
5.2
± 0.2
|
5621 |
EN300-36911_4_1
|
|
CNC(=O)NCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.3
|
5.2
± 0.2
|
5622 |
ALP-POS-5bb456a5-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCN(CC5)C6CCOC6 |
−7.1
± 0.4
|
5.2
± 0.3
|
5623 |
LON-WEI-4d77710c-59
|
|
Cn1cc(c2ccccc2c1=O)NC(=O)N(Cc3ccco3)CC4CCCO4 |
−7.1
± 0.4
|
5.2
± 0.3
|
5624 |
EN300-1212475_1_2
|
|
CC1(CC(=O)NC[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C |
−7.1
± 0.2
|
5.2
± 0.2
|
5625 |
EDJ-MED-50011917-1
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)CC4CC(=O)N4 |
−7.07
± 0.07
|
5.15
± 0.05
|
5626 |
MIC-UNK-cdc2493e-14
|
|
c1ccc2c(c1)cncc2NC(=O)N(c3cccc(c3)Cl)C4CCC(C4)N5CCCCC5 |
−7.1
± 0.3
|
5.2
± 0.2
|
5627 |
JOH-UNI-ea72002d-6
|
|
C=CS(=O)(=O)NN(c1cncc2c1cccc2)C(=O)C3CCOc4c3cc(cc4)Cl |
−7.1
± 0.2
|
5.2
± 0.1
|
5628 |
LON-WEI-4d77710c-5
|
|
Cn1cc(c2ccccc2c1=O)NC(=O)Nc3ccc(c(c3)OC)OC |
−7.1
± 0.4
|
5.2
± 0.3
|
5629 |
EN300-188377_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5ccnc6c5n[nH]n6 |
−7.1
± 0.3
|
5.1
± 0.2
|
5630 |
EN300-313438_2_1
|
|
Cn1c2c(cn1)c(ncn2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−7.1
± 0.3
|
5.1
± 0.2
|
5631 |
MAK-UNK-ffc90da7-9
|
|
CC1C(CCO1)SCC(C)c2ccc3c(c2)cncc3NC(=O)Cc4cccc(c4)Cl |
−7.1
± 0.2
|
5.1
± 0.1
|
5632 |
EN300-741926_2_3
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@H]([C@H](C5)F)O |
−7.1
± 0.3
|
5.1
± 0.3
|
5633 |
MAT-POS-e9e99895-10
|
|
CC(c1ccc(c(c1)Cl)Cl)(C(=O)Nc2cncc3c2cccc3)NC(=O)CN |
−7.1
± 0.3
|
5.1
± 0.2
|
5634 |
EN300-321053_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@H]5CCOC[C@@H]5O |
−7.1
± 0.2
|
5.1
± 0.1
|
5635 |
MAT-POS-2905de8c-2
|
|
CNC1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.3
|
5.1
± 0.2
|
5636 |
PET-UNK-c9c1e0d8-2
|
|
C#Cc1cccc(c1)CC(=O)Nc2cncc3c2cccc3 |
−7.06
± 0.09
|
5.14
± 0.07
|
5637 |
DAR-DIA-0cde14eb-57
|
|
CC(c1cccc(c1)C2(CC2)F)C(=O)Nc3cncc4c3cccc4 |
−7.1
± 0.2
|
5.1
± 0.2
|
5638 |
MAT-POS-bb423b95-6
|
|
c1ccc2c(c1)c(c[nH]c2=O)NC(=O)Cc3cccc(c3)Cl |
−7.1
± 0.3
|
5.1
± 0.2
|
5639 |
RAL-THA-2d450e86-5
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3ccc(cc3)C#N |
−7.0
± 0.3
|
5.1
± 0.2
|
5640 |
EN300-18074_2_1
|
|
CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.2
|
5.1
± 0.1
|
5641 |
DAR-DIA-5d6f1b43-12
|
|
c1ccc2c(c1)cncc2N3CC4(CCCCC4)CN(C3=O)c5cccc(c5)Cl |
−7.0
± 0.4
|
5.1
± 0.3
|
5642 |
LON-WEI-5e7d1b3e-39
|
|
CC(CCc1ccco1)NC(=O)Nc2cn(c(=O)c3c2cccc3)C |
−7.0
± 0.3
|
5.1
± 0.2
|
5643 |
EN300-7433071_1_2
|
|
C[NH+](C)[C@]1(CCCN(C1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C(=O)N |
−7.0
± 0.3
|
5.1
± 0.2
|
5644 |
MAT-POS-3b92565d-9
|
|
Cn1cc(c2ccccc2c1=O)NC(=O)Cc3cc(cc(c3)Cl)OC4CC(=O)N4 |
−7.0
± 0.4
|
5.1
± 0.3
|
5645 |
EN300-1689158_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(n[nH]5)C(=O)N |
−7.0
± 0.3
|
5.1
± 0.2
|
5646 |
ALP-POS-2da19ca7-4
|
|
Cn1c(nnn1)C2CCN(CC2)C(=O)C[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−7.0
± 0.4
|
5.1
± 0.3
|
5647 |
ALP-UNI-0676e700-24
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5[C@H](CC(=O)N5)C(F)(F)F |
−7.0
± 0.3
|
5.1
± 0.2
|
5648 |
EN300-1716006_1_1
|
|
CN(CC1NC(=O)NN1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.2
|
5.1
± 0.2
|
5649 |
ALP-POS-f13221e1-2
|
|
c1ccc2c(c1)cncc2NC(=O)COc3cccc(c3)Cl |
−7.02
± 0.10
|
5.12
± 0.07
|
5650 |
RAL-THA-05e671eb-21
|
|
c1ccc2c(c1)cncc2NC(=O)C3CCOc4c3cccc4Cl |
−7.0
± 0.2
|
5.1
± 0.1
|
5651 |
EN300-24014_1_2
|
|
CS(=O)(=O)[N@]1CCCC[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.4
|
5.1
± 0.3
|
5652 |
EN300-303519_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnn6c5OCC6 |
−7.0
± 0.3
|
5.1
± 0.2
|
5653 |
JAN-GHE-f375bf5b-1
|
|
CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC2CCNC2=O)C(=O)Nc3cncc4c3cccc4 |
−7.0
± 0.4
|
5.1
± 0.3
|
5654 |
EN300-746187_1_2
|
|
CC1[NH2+]C2CC[C@@H](C[N@]2N1)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−7.0
± 0.7
|
5.1
± 0.5
|
5655 |
JOH-UNI-f51e3bbc-2
|
|
COc1c2ccccc2c(cn1)NC(=O)C3CCOc4c3cc(cc4)Cl |
−7.0
± 0.1
|
5.10
± 0.08
|
5656 |
JOH-UNI-f51e3bbc-1
|
|
c1ccc2c(c1)c(c[nH]c2=O)NC(=O)C3CCOc4c3cc(cc4)Cl |
−7.0
± 0.3
|
5.1
± 0.2
|
5657 |
EN300-315854_2_2
|
|
C[C@]1(CCNC(=O)C1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.4
|
5.1
± 0.3
|
5658 |
EN300-75030_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC[C@@H]5CCC(=O)N5 |
−7.0
± 0.3
|
5.1
± 0.2
|
5659 |
JOH-UNI-ee5ed7c8-5
|
|
CN(c1cncc2c1c(ccc2)C(=O)C#C)C(=O)Cc3cccc(c3)Cl |
−7.0
± 0.3
|
5.1
± 0.2
|
5660 |
EN300-137243_2_1
|
|
CN(C)c1ncc(o1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−7.0
± 0.2
|
5.1
± 0.2
|
5661 |
NAU-LAT-b7d8c353-8_1
|
|
c1cc(c2cncc(c2c1)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl)C[NH3+] |
−7.0
± 0.1
|
5.07
± 0.09
|
5662 |
ALF-EVA-ced740bd-1
|
|
COc1c(ccc2c1c(cnc2)NC(=O)C3CCOc4c3cc(cc4)Cl)Cl |
−6.96
± 0.09
|
5.07
± 0.06
|
5663 |
EN300-118760_4_1
|
|
C[C@@](C1CC1)(C(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−6.9
± 0.4
|
5.1
± 0.3
|
5664 |
EN300-6486793_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCCC5)S(=O)(=O)N |
−6.9
± 0.3
|
5.1
± 0.2
|
5665 |
EN300-76387_1_1
|
|
C[C@@H](Cc1[nH]nnn1)NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.3
|
5.1
± 0.3
|
5666 |
JOH-UNI-ee5ed7c8-10
|
|
CN(c1c2ccccc2cnc1CC(F)(F)F)C(=O)Cc3cccc(c3)Cl |
−6.9
± 0.4
|
5.0
± 0.3
|
5667 |
EN300-31845_2_1
|
|
COCCN1C[C@@H](CC1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.2
|
5.0
± 0.2
|
5668 |
RAL-THA-2d450e86-40
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3ccccc3C#N |
−6.9
± 0.3
|
5.0
± 0.2
|
5669 |
MIC-UNK-6ab519a7-1
|
|
CC(=O)N1CCN(CC1)C(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.4
|
5.0
± 0.3
|
5670 |
EN300-6792206_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H](C5CCOCC5)O |
−6.9
± 0.2
|
5.0
± 0.2
|
5671 |
EN300-1590388_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)Cn5cc(cn5)C#N |
−6.9
± 0.3
|
5.0
± 0.2
|
5672 |
EDJ-MED-2f867453-2
|
|
CC1(CNc2c1cc(c(c2)Cl)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.2
|
5.0
± 0.2
|
5673 |
EDJ-MED-4c7486ba-1
|
|
CN(C)CC(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
5.0
± 0.3
|
5674 |
EN300-31210_1_2
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NS(=O)(=O)C |
−6.9
± 0.3
|
5.0
± 0.2
|
5675 |
EN300-187998_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CC[C@@]6(C5)CC(=O)NC6 |
−6.9
± 0.3
|
5.0
± 0.2
|
5676 |
EN300-51735_2_1
|
|
C[NH+](C)CCN1C[C@@H](CC1=O)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.3
|
5.0
± 0.2
|
5677 |
EN300-99391_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)CO[C@@H]5CCOC5 |
−6.9
± 0.2
|
5.0
± 0.1
|
5678 |
EN300-188915_1_2
|
|
Cc1ccn(c(=O)c1)C[C@](C)(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−6.9
± 0.3
|
5.0
± 0.2
|
5679 |
LON-WEI-4d77710c-48
|
|
CC(C)Cn1cc(c2ccccc2c1=O)NC(=O)NCCc3cc(ccc3OC)OC |
−6.9
± 0.7
|
5.0
± 0.5
|
5680 |
EN300-217494_1_2
|
|
C[C@]([C@@H]1CCOC1)(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−6.9
± 0.3
|
5.0
± 0.2
|
5681 |
EN300-206646_2_1
|
|
CS(=O)(=O)c1cncc(n1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.3
|
5.0
± 0.2
|
5682 |
RAL-THA-05e671eb-14
|
|
COc1ccc2c(c1)OCCC2C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.2
|
5.0
± 0.2
|
5683 |
EN300-51028_4_1
|
|
CC(C)S(=O)(=O)CC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
5.0
± 0.2
|
5684 |
EN300-132615_1_1
|
|
C[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−6.9
± 0.3
|
5.0
± 0.2
|
5685 |
MIC-UNK-cdc2493e-22
|
|
c1ccc2c(c1)cncc2NC(=O)N(CCn3ccnn3)c4cccc(c4)Cl |
−6.9
± 0.4
|
5.0
± 0.3
|
5686 |
EN300-96544_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCCc5[nH]c(=O)[nH]n5 |
−6.9
± 0.2
|
5.0
± 0.2
|
5687 |
EN300-100180_2_1
|
|
CC(=O)N1CC[C@@H](C1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.4
|
5.0
± 0.3
|
5688 |
EN300-114805_2_1
|
|
Cn1c(ccn1)CC(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.3
|
5.0
± 0.2
|
5689 |
FRA-DIA-c7e803f4-1
|
|
c1ccc2c(c1)cncc2NC(=O)C3COc4c3cccc4Cl |
−6.87
± 0.07
|
5.01
± 0.05
|
5690 |
EDJ-MED-9e38fd34-2
|
|
C[C@]1(c2cc(ccc2NC1=O)Cl)C(=O)Nc3cncc4c3cccc4 |
−6.9
± 0.3
|
5.0
± 0.3
|
5691 |
EN300-251396_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@](C5)(CO)O |
−6.9
± 0.5
|
5.0
± 0.3
|
5692 |
NIR-THE-d08c3b48-1
|
|
CC(=O)N1CCN(CC1)CC(=O)Nc2cncc3c2cccc3 |
−6.9
± 0.4
|
5.0
± 0.3
|
5693 |
EN300-378373_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)COC5CC5 |
−6.9
± 0.1
|
5.0
± 0.1
|
5694 |
DAR-DIA-5ff57136-19
|
|
CN(C)C/C=C/C(=O)N(c1cncc2c1cccc2)C(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−6.9
± 0.3
|
5.0
± 0.3
|
5695 |
ALP-POS-2da19ca7-1
|
|
CCNC(=O)CN1CCN(CC1)C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−6.9
± 0.4
|
5.0
± 0.3
|
5696 |
MIC-UNK-bcd487e9-6
|
|
c1ccc2c(c1)cncc2NC(=O)N(CC3CCCS3(=O)=O)c4cccc(c4)Cl |
−6.9
± 0.4
|
5.0
± 0.3
|
5697 |
EN300-6746326_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@H]5CCC(=O)NC5 |
−6.9
± 0.3
|
5.0
± 0.2
|
5698 |
EN300-1178005_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cc(on5)C#N |
−6.9
± 0.2
|
5.0
± 0.1
|
5699 |
RAL-THA-2d450e86-34
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3ccncc3Cl |
−6.9
± 0.2
|
5.0
± 0.2
|
5700 |
DAR-DIA-076fb6ea-3
|
|
COC(=O)/C=C/C(=O)N(c1cncc2c1cccc2)C(=O)Cc3cccc(c3)Cl |
−6.9
± 0.5
|
5.0
± 0.4
|