Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2901 |
EN300-55355_1_2
|
|
CNC(=O)[C@H]1CCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2902 |
EN300-220194_2_1
|
|
C[C@@H]([C@@H](C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)OC |
−9.5
± 0.3
|
6.9
± 0.2
|
2903 |
EN300-182124_2_1
|
|
COC1(CC1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2904 |
EN300-67533_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@H](C5CC5)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2905 |
EN300-6499639_3_1
|
|
Cc1cc(n(n1)C)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2906 |
MAT-POS-de59a476-4
|
|
COCCOC(c1ccc(c(c1)Cl)Cl)C(=O)Nc2cncc3c2cccc3 |
−9.5
± 0.2
|
6.9
± 0.2
|
2907 |
EN300-1268016_1_6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@H]5C[C@@H]6[C@H]5C[C@@H](C6)C(=O)N |
−9.5
± 0.4
|
6.9
± 0.3
|
2908 |
EN300-6494693_1_1
|
|
CCn1c(ncn1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2909 |
EN300-1708899_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5C[C@@H](CCO5)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2910 |
EN300-248352_1_1
|
|
Cn1c(cc(=O)[nH]1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2911 |
MIC-UNK-bcd487e9-9
|
|
Cn1cc(nn1)CN(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.4
|
6.9
± 0.3
|
2912 |
EN300-1608992_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@](C5)(C#N)C(=O)N |
−9.5
± 0.3
|
6.9
± 0.2
|
2913 |
BEN-DND-c852c98b-4_1
|
|
c1cc2cncc(c2cc1O)NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−9.49
± 0.05
|
6.92
± 0.04
|
2914 |
EN300-378722_3_2
|
|
CN1CC[C@H](C1=O)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2915 |
EN300-94900_2_1
|
|
CS(=O)(=O)Cc1nc(on1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.5
|
6.9
± 0.3
|
2916 |
EN300-1387104_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CCS5(=O)=O |
−9.5
± 0.3
|
6.9
± 0.2
|
2917 |
EN300-203118_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@](C5)(CO)F |
−9.5
± 0.3
|
6.9
± 0.2
|
2918 |
EN300-42269_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cnns5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2919 |
EN300-6082676_1_4
|
|
C[C@H]1C[C@H](CCS1(=O)=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2920 |
EN300-105110_4_1
|
|
Cc1cc(n[nH]1)CC(=O)NCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2921 |
ED_-GRI-5b13fbe2-56
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCCc5[nH]nnn5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2922 |
EN300-43047_1_1
|
|
CC(=O)N[C@@H](CC=C)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.3
|
6.9
± 0.2
|
2923 |
EN300-203118_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@](C5)(CO)F |
−9.5
± 0.3
|
6.9
± 0.2
|
2924 |
MAT-POS-281d2ee9-2
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)c4[nH]cnn4 |
−9.5
± 0.3
|
6.9
± 0.2
|
2925 |
LAU-MED-88a3970a-5
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4CCCO)Cl |
−9.5
± 0.2
|
6.9
± 0.1
|
2926 |
EN300-04491_3_1
|
|
COCCN(CCOC)C(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.5
|
6.9
± 0.4
|
2927 |
MAT-POS-fce787c2-7
|
|
CC(c1ccc(c(c1)Cl)Cl)(C(=O)Nc2cncc3c2cccc3)N |
−9.5
± 0.3
|
6.9
± 0.3
|
2928 |
EDJ-MED-fcba3f31-4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H](CF)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2929 |
EN300-210552_1_1
|
|
CC(=O)N1CCC[C@@](C1)(C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2930 |
EN300-73507_1_1
|
|
CC(=O)NCCNC(=O)CCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.3
|
6.9
± 0.2
|
2931 |
ALP-UNI-dbbfd3db-4
|
|
Cc1nc2n(n1)C[C@@H](CC2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.5
± 0.3
|
6.9
± 0.2
|
2932 |
EN300-221518_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCCO |
−9.5
± 0.2
|
6.9
± 0.1
|
2933 |
EN300-202922_2_2
|
|
C[C@H]([C@@](C)(C(=O)NC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2934 |
EN300-23317_3_1
|
|
C[C@@H](C(=O)NCCOC)OCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.4
|
6.9
± 0.3
|
2935 |
EN300-149975_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5(CCC5)CO |
−9.5
± 0.3
|
6.9
± 0.2
|
2936 |
EN300-1987964_1_1
|
|
CS(=O)(=O)Cc1cc(no1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.4
|
6.9
± 0.3
|
2937 |
EN300-1664865_3_1
|
|
Cn1c2c(nn1)CCC[C@@H]2C(=O)NCC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.5
± 0.4
|
6.9
± 0.3
|
2938 |
EN300-6494158_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@H]5C[C@@H](CO5)CO |
−9.5
± 0.3
|
6.9
± 0.2
|
2939 |
EN300-295515_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@H](C5)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2940 |
EN300-55087_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@@H](C5)N6CCNC6=O |
−9.5
± 0.2
|
6.9
± 0.2
|
2941 |
EN300-265285_2_2
|
|
C[C@H]1Cn2c(cc(n2)C(=O)NC[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6)C(=O)N1 |
−9.5
± 0.3
|
6.9
± 0.2
|
2942 |
EN300-132157_2_2
|
|
C[C@]1(CC(=O)NC1)C(=O)NC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2943 |
EN300-741822_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@H]5CC[C@H]([C@H](C5)O)O |
−9.5
± 0.2
|
6.9
± 0.2
|
2944 |
EN300-92605_1_1
|
|
Cn1cc(cn1)C2C[C@H](ON2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.5
± 0.4
|
6.9
± 0.3
|
2945 |
EN300-188582_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCC[C@@H](C5)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2946 |
EN300-28871_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCn5ccnn5 |
−9.5
± 0.2
|
6.9
± 0.1
|
2947 |
EN300-6478432_1_1
|
|
Cn1c(nn(c1=O)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)C6CC6 |
−9.5
± 0.4
|
6.9
± 0.3
|
2948 |
EN300-264301_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]5CCC(=O)N5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2949 |
EN300-190283_3_1
|
|
Cn1cncc1[C@@H](C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.5
± 0.4
|
6.9
± 0.3
|
2950 |
MAT-POS-e9e99895-12
|
|
CC(c1ccc(c(c1)Cl)Cl)(C(=O)Nc2cncc3c2cccc3)NC(=O)CCN(C)C |
−9.5
± 0.5
|
6.9
± 0.3
|
2951 |
EN300-6082676_1_3
|
|
C[C@@H]1C[C@H](CCS1(=O)=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2952 |
EN300-214038_2_2
|
|
C[C@H](CN(CCO)C(=O)CC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2953 |
PET-UNK-b87f07d0-4
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)CCCNc4nnco4 |
−9.5
± 0.5
|
6.9
± 0.4
|
2954 |
EN300-7457160_3_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCOCC5C[C@@H](ON5)CC6(COC6)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2955 |
EN300-1604607_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C56CC(C5)OC6 |
−9.5
± 0.3
|
6.9
± 0.2
|
2956 |
EN300-185378_1_1
|
|
C[C@@H](CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2957 |
EN300-43939_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CNC(=O)CC(F)(F)F |
−9.5
± 0.3
|
6.9
± 0.2
|
2958 |
EN300-14006_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@H]5CCS(=O)(=O)C5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2959 |
EN300-70033_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N5CCC[C@H]5CO |
−9.5
± 0.3
|
6.9
± 0.2
|
2960 |
EN300-100741_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)c5[nH]ncn5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2961 |
EN300-96362_1_2
|
|
C[C@H]([C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C5CC5)O |
−9.5
± 0.3
|
6.9
± 0.2
|
2962 |
EN300-305996_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5COC(=O)N5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2963 |
EN300-332601_1_2
|
|
CC[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C |
−9.5
± 0.2
|
6.9
± 0.2
|
2964 |
EN300-23019_2_1
|
|
CC(C)(C)NC(=O)CN(C)C(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.3
|
6.9
± 0.2
|
2965 |
EN300-34542_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCCC[C@H]5C(=O)N |
−9.5
± 0.4
|
6.9
± 0.3
|
2966 |
ED_-GRI-5b13fbe2-49
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(CN)c5cn(nn5)CC6CC6 |
−9.5
± 0.3
|
6.9
± 0.2
|
2967 |
EN300-76205_3_1
|
|
CC(C)(C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)C |
−9.5
± 0.5
|
6.9
± 0.3
|
2968 |
MIC-UNK-5a93dd5f-3
|
|
c1ccc2c(c1)cncc2NC(=O)C(c3cccc(c3)Cl)N4CCC5CCCCC5C4 |
−9.5
± 0.2
|
6.9
± 0.2
|
2969 |
EN300-31184_1_2
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)C(C)C |
−9.5
± 0.3
|
6.9
± 0.2
|
2970 |
EN300-83558_3_1
|
|
Cc1ccnn1CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2971 |
EN300-129424_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H]5CC[C@@H]5O |
−9.5
± 0.2
|
6.9
± 0.2
|
2972 |
EN300-262204_3_1
|
|
CS(=O)(=O)CC1(COC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.5
|
6.9
± 0.3
|
2973 |
EN300-182084_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)CNC(=O)c5cscn5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2974 |
EN300-54922_2_1
|
|
CS(=O)(=O)[N@]1CCC[C@@H](C1)NC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2975 |
ALF-EVA-5b152d2f-3
|
|
c1cc2cncc(c2cc1Cl)NC(=O)[C@@H]3CCCOc4c3cc(cc4)Cl |
−9.5
± 0.2
|
6.9
± 0.2
|
2976 |
EN300-66770_3_1
|
|
CNC(=O)C1(CC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2977 |
ALP-POS-5bb456a5-3
|
|
Cn1c(nnn1)C2=CCN(CC2)C(=O)CC3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.5
± 0.3
|
6.9
± 0.2
|
2978 |
EN300-68203_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@H]5CCC(=O)N5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2979 |
EN300-6494158_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC[C@@H]5C[C@@H](CO5)CO |
−9.5
± 0.4
|
6.9
± 0.3
|
2980 |
JAG-UCB-706446eb-8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)Cc5cccc(c5)CN |
−9.5
± 0.3
|
6.9
± 0.2
|
2981 |
EN300-14437_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CCS(=O)(=O)C5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2982 |
EN300-6482296_3_8
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@H]5CO[C@H]6[C@H]5COC6 |
−9.5
± 0.3
|
6.9
± 0.2
|
2983 |
EN300-259063_1_1
|
|
CC(=O)N1CCC[C@@](C1)(CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.5
± 0.3
|
6.9
± 0.3
|
2984 |
EN300-6482296_2_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@H]5CO[C@H]6[C@@H]5COC6 |
−9.5
± 0.3
|
6.9
± 0.2
|
2985 |
ED_-GRI-5b13fbe2-15
|
|
CN(CCN)CCOCCO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.4
|
6.9
± 0.3
|
2986 |
EN300-70487_2_1
|
|
Cc1[nH]nc(n1)CNC(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.2
|
6.9
± 0.2
|
2987 |
EN300-30768_1_3
|
|
C[C@@H]1C[C@H]1C(=O)NCC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2988 |
EN300-160080_2_1
|
|
CS(=O)(=O)C1NNC(S1)COC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.5
± 0.4
|
6.9
± 0.3
|
2989 |
EN300-238405_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@@H]5CC(=O)NC5 |
−9.5
± 0.3
|
6.9
± 0.2
|
2990 |
EN300-30419_3_1
|
|
CS(=O)(=O)NCC(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.5
± 0.4
|
6.9
± 0.3
|
2991 |
EN300-198240_1_1
|
|
Cn1cc(cn1)[C@@H](C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)OC |
−9.5
± 0.3
|
6.9
± 0.2
|
2992 |
EN300-6970573_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC5(COC5)CF |
−9.5
± 0.3
|
6.9
± 0.2
|
2993 |
EN300-1253122_1_1
|
|
CCN(C)C(=O)CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.4
± 0.2
|
6.9
± 0.1
|
2994 |
MAT-POS-de59a476-6
|
|
c1ccc2c(c1)cncc2NC(=O)C(c3ccc(c(c3)Cl)Cl)OCC(=O)NC4CC4 |
−9.4
± 0.3
|
6.9
± 0.2
|
2995 |
EDJ-MED-d203f206-32
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H]6COCCN6C(=O)C5 |
−9.4
± 0.3
|
6.9
± 0.2
|
2996 |
DAR-DIA-6be260fc-4
|
|
CC(C)[C@H]1CN(C(=O)C12CNc3c2cc(cc3)Cl)c4cncc5c4cccc5 |
−9.4
± 0.3
|
6.9
± 0.2
|
2997 |
EN300-317082_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC5COC5 |
−9.4
± 0.2
|
6.9
± 0.2
|
2998 |
EN300-255795_1_2
|
|
CN1C[C@H](NC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.4
± 0.2
|
6.9
± 0.2
|
2999 |
EN300-122656_2_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@]5(CCSC5)O |
−9.4
± 0.4
|
6.9
± 0.3
|
3000 |
MAK-UNK-c749d764-6
|
|
CC(CNCCCO)C(c1cccc(c1)Cl)C(=O)Nc2cncc3c2cccc3 |
−9.4
± 0.5
|
6.9
± 0.3
|