Rank |
Compound |
SMILES |
ΔG / kcal M-1 |
pIC50 |
2701 |
EN300-181492_1_1
|
|
C=C[C@@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.3
|
7.0
± 0.2
|
2702 |
EDG-MED-90036822-100
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCF |
−9.6
± 0.2
|
7.0
± 0.1
|
2703 |
EN300-270710_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCCS(=O)(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
2704 |
EN300-21303_4_1
|
|
CCOCC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
2705 |
EN300-55250_1_1
|
|
COCCOCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.2
|
2706 |
MAT-POS-cc05818f-1
|
|
c1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)C#N |
−9.6
± 0.3
|
7.0
± 0.2
|
2707 |
EN300-384234_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(c6cn[nH]n6)O |
−9.6
± 0.4
|
7.0
± 0.3
|
2708 |
EN300-131219_1_1
|
|
Cc1nc(no1)Cn2cc(cn2)C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2709 |
EN300-6497238_1_1
|
|
C[C@@H]1CS(=O)(=O)CCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.4
|
7.0
± 0.3
|
2710 |
EN300-1073320_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@@H](C5(CCC5)O)O |
−9.6
± 0.4
|
7.0
± 0.3
|
2711 |
EN300-396146_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)(CO)CO |
−9.6
± 0.3
|
7.0
± 0.2
|
2712 |
EN300-174668_3_2
|
|
CO[C@]1(CCOC1)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.4
|
7.0
± 0.3
|
2713 |
EN300-138953_1_2
|
|
CC(C)N(C[C@H](CO)O)C(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.5
|
7.0
± 0.4
|
2714 |
EN300-68203_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[C@@H]5CCC(=O)N5 |
−9.6
± 0.2
|
7.0
± 0.1
|
2715 |
EN300-317082_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCOC5COC5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2716 |
EN300-82616_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5CCCNC5=O |
−9.6
± 0.3
|
7.0
± 0.2
|
2717 |
EN300-17184_4_1
|
|
C=CCNC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
2718 |
EN300-133788_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)N[C@@]5(CCOC5)CO |
−9.6
± 0.4
|
7.0
± 0.3
|
2719 |
EN300-2972220_3_1
|
|
CC(C)[C@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
2720 |
EN300-761209_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn(c5)CCO |
−9.6
± 0.2
|
7.0
± 0.2
|
2721 |
EN300-154201_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC[C@H]5CO |
−9.6
± 0.4
|
7.0
± 0.3
|
2722 |
EN300-59487_4_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCCNC(=O)[C@@H]5CC(=O)NC5 |
−9.6
± 0.4
|
7.0
± 0.3
|
2723 |
EN300-7003350_4_1
|
|
CCNC(=O)COCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.1
|
2724 |
EN300-154179_1_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6C[C@]6(C5)CO |
−9.6
± 0.3
|
7.0
± 0.2
|
2725 |
EN300-7463161_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C5CC(C5)n6cnnc6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2726 |
EN300-332838_1_1
|
|
CN1[C@@H](COC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2727 |
EN300-08259_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OCC(=O)NCCCN5CCCC5=O |
−9.6
± 0.4
|
7.0
± 0.3
|
2728 |
EN300-124918_1_1
|
|
CN1C(=O)NC(N1)CO[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2729 |
EN300-195790_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N[C@@H](CCO)CO |
−9.6
± 0.3
|
7.0
± 0.2
|
2730 |
EN300-66764_1_1
|
|
COC(=O)[C@@H]1C[C@@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
2731 |
ALF-EVA-0b412456-6
|
|
CNc1ccc2c(c1)cncc2NC(=O)Cc3cc(cc(c3)Cl)OC4CC(=O)N4 |
−9.6
± 0.3
|
7.0
± 0.2
|
2732 |
EN300-97758_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCF |
−9.6
± 0.2
|
7.0
± 0.1
|
2733 |
EN300-73662_1_1
|
|
COC(=O)C[C@H](CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.4
|
7.0
± 0.3
|
2734 |
EN300-6480588_1_1
|
|
COc1ccnc(n1)CC(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.3
|
2735 |
EN300-90206_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6C[C@@H](C5)C6O |
−9.6
± 0.3
|
7.0
± 0.2
|
2736 |
EN300-1644723_1_6
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5[C@@H]6[C@H]5COCC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2737 |
ALP-UNI-dbbfd3db-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)Cn5cnc(n5)C(F)(F)F |
−9.6
± 0.3
|
7.0
± 0.2
|
2738 |
EN300-70064_1_1
|
|
CNC(=O)C1(CCC1)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
2739 |
EN300-120282_4_1
|
|
Cn1cc(nn1)COCCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2740 |
EN300-141809_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H]5CC56CCS(=O)(=O)CC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2741 |
EN300-7355979_1_1
|
|
Cn1cnc2c(c1=O)[nH]nc2C(=O)N[C@]3(CCOc4c3cc(cc4)Cl)C(=O)Nc5cncc6c5cccc6 |
−9.6
± 0.2
|
7.0
± 0.2
|
2742 |
EN300-1241327_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COCC(=O)N5CCOCC5 |
−9.6
± 0.2
|
7.0
± 0.2
|
2743 |
EN300-1720418_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NCC5CCON5 |
−9.6
± 0.2
|
7.0
± 0.2
|
2744 |
EN300-55072_1_2
|
|
C[C@H](CO)C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.2
|
7.0
± 0.2
|
2745 |
EN300-705381_1_1
|
|
COC[C@H]1C[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
2746 |
EN300-6734977_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCC(=O)NC56CC(C5)OC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2747 |
EDJ-MED-40433386-7
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)[C@]5(CCSC5)O |
−9.6
± 0.3
|
7.0
± 0.2
|
2748 |
PET-UNK-29afea89-2_1
|
|
CO[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.1
|
6.99
± 0.10
|
2749 |
EN300-66518_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC(C5)n6cncn6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2750 |
EN300-43206_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C[N@]5CCCS5(=O)=O |
−9.6
± 0.3
|
7.0
± 0.2
|
2751 |
EN300-6493060_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@H]6[C@@H]([C@@H]5CO6)O |
−9.6
± 0.3
|
7.0
± 0.2
|
2752 |
EN300-6501360_2_1
|
|
CN(C)C(=O)NC[C@@H](COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.4
|
7.0
± 0.3
|
2753 |
EN300-318341_2_1
|
|
CN(C1CS(=O)(=O)C1)C(=O)CC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2754 |
KAD-UNI-8a629cb0-47
|
|
Cn1cc(nn1)CC(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2755 |
KAD-UNI-8a629cb0-34
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)[C@@H]5[C@@H]6[C@@H]5COCC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2756 |
EN300-02067_3_1
|
|
C[C@@H](COC)NC(=O)COCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.3
|
2757 |
EN300-1600517_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)OC[C@@H](CO)F |
−9.6
± 0.2
|
7.0
± 0.2
|
2758 |
EN300-305282_3_1
|
|
COC[C@@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−9.6
± 0.4
|
7.0
± 0.3
|
2759 |
EN300-35612_1_1
|
|
CN(CC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)C(=O)COC |
−9.6
± 0.3
|
7.0
± 0.2
|
2760 |
EN300-67439_1_1
|
|
CC[C@@H]1C(=O)NCCN1C(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2761 |
EN300-155362_1_4
|
|
C[C@H]1CC(=O)N[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2762 |
EN300-28113_2_2
|
|
C[C@H](C(=O)N1CCC(CC1)C(=O)N)OC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2763 |
EN300-23214_2_2
|
|
CCCNC(=O)[C@H](C)NC(=O)COC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.4
|
7.0
± 0.3
|
2764 |
EN300-68875_3_1
|
|
CNS(=O)(=O)CCCOCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
2765 |
EN300-1608992_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@](C5)(C#N)C(=O)N |
−9.6
± 0.2
|
7.0
± 0.2
|
2766 |
EN300-249764_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@H](C5CCC5)O |
−9.6
± 0.2
|
7.0
± 0.2
|
2767 |
EN300-51257_3_2
|
|
C[C@H](C(=O)NCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)OC |
−9.6
± 0.3
|
7.0
± 0.2
|
2768 |
EN300-332838_1_2
|
|
CN1[C@H](COC1=O)C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.2
|
7.0
± 0.2
|
2769 |
MIC-UNK-bcd487e9-1
|
|
c1ccc(cc1)CN(c2cccc(c2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
2770 |
MAK-UNK-83e0a0b4-3
|
|
c1ccc2c(c1)cncc2N(CCNC3CNC3)C(=O)C4CCOc5c4cc(cc5)Cl |
−9.6
± 0.3
|
7.0
± 0.2
|
2771 |
EN300-6746631_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5nnc6n5CCCC6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2772 |
EN300-128463_4_1
|
|
CNC(=O)CC(=O)NCCC[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
2773 |
EN300-4698402_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5C[C@H]5F |
−9.6
± 0.2
|
7.0
± 0.1
|
2774 |
EN300-255496_3_1
|
|
C[N@@]1CC[C@@H](S1(=O)=O)C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.4
|
7.0
± 0.3
|
2775 |
EN300-6487407_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)COC[C@@H]5[C@H](CC(=O)O5)O |
−9.6
± 0.3
|
7.0
± 0.2
|
2776 |
EN300-128277_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)C(=O)NCC(F)F |
−9.6
± 0.3
|
7.0
± 0.2
|
2777 |
EN300-1179673_3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CCNC(=O)Cc5cccc(c5)C(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
2778 |
EN300-103979_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cc6c(nc5)OCC(=O)N6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2779 |
EN300-333677_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5C[C@@H]([C@@H](C5)CO)CO |
−9.6
± 0.3
|
7.0
± 0.2
|
2780 |
EN300-123623_1_1
|
|
C[C@@H](CNC(=O)C[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)S(=O)(=O)N |
−9.6
± 0.3
|
7.0
± 0.2
|
2781 |
EN300-126389_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)[C@@H]5COC(=O)N5 |
−9.6
± 0.2
|
7.0
± 0.2
|
2782 |
EN300-25960_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)C5(CCCC5)O |
−9.6
± 0.4
|
7.0
± 0.3
|
2783 |
EN300-00271_1_2
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)NC(=O)N |
−9.6
± 0.2
|
7.0
± 0.2
|
2784 |
EN300-6759512_2_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CNC(=O)c5cn(nn5)[C@@H]6COC[C@@H]6F |
−9.6
± 0.3
|
7.0
± 0.2
|
2785 |
EN300-7463275_1_2
|
|
C[C@H]([C@@H]1C[C@H]1NC(=O)C[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.6
± 0.3
|
7.0
± 0.2
|
2786 |
EN300-146051_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5ccc(nc5)CO |
−9.6
± 0.2
|
7.0
± 0.2
|
2787 |
EN300-114593_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)c5cnn6c5cccn6 |
−9.6
± 0.2
|
7.0
± 0.2
|
2788 |
EN300-155362_3_4
|
|
C[C@H]1CC(=O)N[C@H]1C(=O)NCC[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2789 |
EN300-193679_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)NC[C@]5(CCCOC5)O |
−9.6
± 0.4
|
7.0
± 0.3
|
2790 |
JOH-UNI-f51e3bbc-4
|
|
COc1c(c2ccccc2cn1)NC(=O)C3CCOc4c3cc(cc4)Cl |
−9.6
± 0.1
|
6.97
± 0.10
|
2791 |
EDG-MED-90036822-29
|
|
C[C@H](C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.2
|
7.0
± 0.2
|
2792 |
EN300-122849_1_2
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CCOC[C@H]5c6ncon6 |
−9.6
± 0.3
|
7.0
± 0.2
|
2793 |
MAK-UNK-8be7dca9-2_1
|
|
c1cc2c(cc1CC(=O)N)cncc2NC(=O)[C@@H]3CCOc4c3cc(cc4)Cl |
−9.57
± 0.09
|
6.97
± 0.06
|
2794 |
EN300-10729_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)NC(=O)CCNC(=O)N |
−9.6
± 0.2
|
7.0
± 0.2
|
2795 |
EN300-154693_1_1
|
|
CNC(=O)CCCCC(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4 |
−9.6
± 0.3
|
7.0
± 0.2
|
2796 |
EN300-6729572_1_8
|
|
C[C@H]([C@H]1C[C@H]1C(=O)N[C@]2(CCOc3c2cc(cc3)Cl)C(=O)Nc4cncc5c4cccc5)O |
−9.6
± 0.2
|
7.0
± 0.2
|
2797 |
EN300-104746_1_2
|
|
CC[C@](C)(C(=O)N[C@]1(CCOc2c1cc(cc2)Cl)C(=O)Nc3cncc4c3cccc4)O |
−9.6
± 0.2
|
7.0
± 0.2
|
2798 |
FRA-DIA-b66f7109-3_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@H]3CCOc4c3cc(cc4Cl)O[C@@H]5CC(=O)N5 |
−9.6
± 0.3
|
7.0
± 0.2
|
2799 |
EN300-365993_1_4
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@H]6CS(=O)(=O)C[C@H]6C5 |
−9.6
± 0.4
|
7.0
± 0.3
|
2800 |
EN300-741926_1_1
|
|
c1ccc2c(c1)cncc2NC(=O)[C@@]3(CCOc4c3cc(cc4)Cl)CC(=O)N5CC[C@@H]([C@@H](C5)F)O |
−9.6
± 0.2
|
7.0
± 0.2
|